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WO2010018438A3 - Tetrazole glycosides - Google Patents

Tetrazole glycosides Download PDF

Info

Publication number
WO2010018438A3
WO2010018438A3 PCT/IB2009/006497 IB2009006497W WO2010018438A3 WO 2010018438 A3 WO2010018438 A3 WO 2010018438A3 IB 2009006497 W IB2009006497 W IB 2009006497W WO 2010018438 A3 WO2010018438 A3 WO 2010018438A3
Authority
WO
WIPO (PCT)
Prior art keywords
tetrazole
glycosides
sglt2
sglt
transporter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2009/006497
Other languages
French (fr)
Other versions
WO2010018438A2 (en
Inventor
Bandi Parthasaradhi Reddy
Kura Rathnakar Reddy
Vedula Manohar Sharma
Musku Madhanmohan Reddy
Poshala Ramesh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hetero Research Foundation
Original Assignee
Hetero Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hetero Research Foundation filed Critical Hetero Research Foundation
Publication of WO2010018438A2 publication Critical patent/WO2010018438A2/en
Publication of WO2010018438A3 publication Critical patent/WO2010018438A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to the tetrazole glycosides derivatives, which are inhibitors of Sodium dependent glucose co transporter (SGLT), particularly SGLT2 and method of treating diseases, conditions and/or disorders inhibited by SGLT2 with them, and processes for preparing them.
PCT/IB2009/006497 2008-08-11 2009-08-05 Tetrazole glycosides Ceased WO2010018438A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1934/CHE/2008 2008-08-11
IN1934CH2008 2008-08-11

Publications (2)

Publication Number Publication Date
WO2010018438A2 WO2010018438A2 (en) 2010-02-18
WO2010018438A3 true WO2010018438A3 (en) 2011-01-20

Family

ID=41669393

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/006497 Ceased WO2010018438A2 (en) 2008-08-11 2009-08-05 Tetrazole glycosides

Country Status (1)

Country Link
WO (1) WO2010018438A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108358863A (en) * 2018-03-08 2018-08-03 湖北佰智昂生物化工有限公司 A kind of method that zinc lewis acid Surfactant-Catalyzed prepares 5 '-substituted tetrazole compounds

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221865B1 (en) * 1995-11-06 2001-04-24 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
WO2004073594A2 (en) * 2003-02-12 2004-09-02 L'oreal Use of an inhibitor of 15-hydroxyprostaglandin dehydrogenase in order to stimulate pigmentation of the skin or skin appendages
WO2004099230A1 (en) * 2003-05-12 2004-11-18 Fujisawa Pharmaceutical Co., Ltd. Monosaccharide compounds
WO2004106293A2 (en) * 2003-05-21 2004-12-09 Bristol-Myers Squibb Company Oxazolyl - and thiazolyl - purine based tricyclic compounds.
WO2005021566A2 (en) * 2003-08-26 2005-03-10 Boehringer Ingelheim International Gmbh Glucopyranosyloxy- pirazoles, drugs containing said compounds the use and production method thereof
EP1637539A1 (en) * 2003-06-20 2006-03-22 Kissei Pharmaceutical Co., Ltd. Pyrazole derivative, drug composition containing the same and production intermediate therefor
WO2006033001A1 (en) * 2004-09-23 2006-03-30 Pfizer Products Inc. Quinoline compounds

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221865B1 (en) * 1995-11-06 2001-04-24 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
WO2004073594A2 (en) * 2003-02-12 2004-09-02 L'oreal Use of an inhibitor of 15-hydroxyprostaglandin dehydrogenase in order to stimulate pigmentation of the skin or skin appendages
WO2004099230A1 (en) * 2003-05-12 2004-11-18 Fujisawa Pharmaceutical Co., Ltd. Monosaccharide compounds
WO2004106293A2 (en) * 2003-05-21 2004-12-09 Bristol-Myers Squibb Company Oxazolyl - and thiazolyl - purine based tricyclic compounds.
EP1637539A1 (en) * 2003-06-20 2006-03-22 Kissei Pharmaceutical Co., Ltd. Pyrazole derivative, drug composition containing the same and production intermediate therefor
WO2005021566A2 (en) * 2003-08-26 2005-03-10 Boehringer Ingelheim International Gmbh Glucopyranosyloxy- pirazoles, drugs containing said compounds the use and production method thereof
WO2006033001A1 (en) * 2004-09-23 2006-03-30 Pfizer Products Inc. Quinoline compounds

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANDREINI, F. ET AL: "Modification of the 1,2,3-triazole ring present in an effective in vitro inhibitor of prostaglandin synthesis", FARMACO , 44(9), 831 -41 CODEN: FRMCE8; ISSN: 0014-827X, 1989, XP002610493 *
HUISGEN, ROLF ET AL: "Ring opening of azoles. II. The formation of 1,3,4-oxadiazoles in the acylation of 5-substituted tetrazoles", CHEMISCHE BERICHTE , 93, 2106 -24 CODEN: CHBEAM; ISSN: 0009-2940, 1960, XP002610492 *
JEFFERSON W TILLEY ET AL: "Carboxylic Acids and Tetrazoles as Isosteric Replacements for Sulfate in Cholecystokinin Analogues", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US, vol. 34, no. 3, 1 March 1991 (1991-03-01), pages 1125 - 1136, XP002413472, ISSN: 0022-2623, DOI: DOI:10.1021/JM00107A037 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108358863A (en) * 2018-03-08 2018-08-03 湖北佰智昂生物化工有限公司 A kind of method that zinc lewis acid Surfactant-Catalyzed prepares 5 '-substituted tetrazole compounds

Also Published As

Publication number Publication date
WO2010018438A2 (en) 2010-02-18

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