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WO2009117112A3 - Appareil de dispersion de poudre, procédé de fabrication et d’utilisation de l’appareil, composants pouvant être utilisés sur l’appareil et d’autres dispositifs, et divers agents actifs - Google Patents

Appareil de dispersion de poudre, procédé de fabrication et d’utilisation de l’appareil, composants pouvant être utilisés sur l’appareil et d’autres dispositifs, et divers agents actifs Download PDF

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Publication number
WO2009117112A3
WO2009117112A3 PCT/US2009/001716 US2009001716W WO2009117112A3 WO 2009117112 A3 WO2009117112 A3 WO 2009117112A3 US 2009001716 W US2009001716 W US 2009001716W WO 2009117112 A3 WO2009117112 A3 WO 2009117112A3
Authority
WO
WIPO (PCT)
Prior art keywords
apparatuses
apparatu
devices
powder dispersion
receptacle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2009/001716
Other languages
English (en)
Other versions
WO2009117112A2 (fr
Inventor
Mark Glusker
William W. Alston
George S. Axford
John Palmer-Felgate
Jonathan Wilkins
Willard R. Foss
Nagaraja Rao
Mark Postich
Neeraj R. Pakala
David S. Maltz
Jeffry G. Weers
Gal Cohen
Keith Try Ung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Priority to EP09722897A priority Critical patent/EP2257326A2/fr
Publication of WO2009117112A2 publication Critical patent/WO2009117112A2/fr
Publication of WO2009117112A3 publication Critical patent/WO2009117112A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016—Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0038—Cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne des procédés et des appareils pour la libération pulmonaire d’une composition, tels que des procédés et des appareils pour disperser des médicaments sous forme de poudre sèche pour une inhalation par un patient. L’invention concerne également des éléments ou des aspects des appareils, comprenant des mécanismes de perforation de réceptacle, des dispositifs d’ouverture, des dispositifs de percussion sur réceptacle et des dispositifs ou des systèmes de verrouillage de réceptacle.
PCT/US2009/001716 2008-03-21 2009-03-18 Appareil de dispersion de poudre, procédé de fabrication et d’utilisation de l’appareil, composants pouvant être utilisés sur l’appareil et d’autres dispositifs, et divers agents actifs Ceased WO2009117112A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09722897A EP2257326A2 (fr) 2008-03-21 2009-03-18 Appareil de dispersion de poudre

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7026008P 2008-03-21 2008-03-21
US61/070,260 2008-03-21
US12607808P 2008-04-30 2008-04-30
US61/126,078 2008-04-30

Publications (2)

Publication Number Publication Date
WO2009117112A2 WO2009117112A2 (fr) 2009-09-24
WO2009117112A3 true WO2009117112A3 (fr) 2010-04-22

Family

ID=40792785

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/001716 Ceased WO2009117112A2 (fr) 2008-03-21 2009-03-18 Appareil de dispersion de poudre, procédé de fabrication et d’utilisation de l’appareil, composants pouvant être utilisés sur l’appareil et d’autres dispositifs, et divers agents actifs

Country Status (2)

Country Link
EP (1) EP2257326A2 (fr)
WO (1) WO2009117112A2 (fr)

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DK2230934T3 (da) 2007-12-14 2012-11-26 Aerodesigns Inc Afgivelse af aerosoliserbare næringsmiddelprodukter
SG2014007389A (en) 2009-01-29 2014-04-28 Forsight Vision4 Inc Posterior segment drug delivery
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
WO2013022801A1 (fr) 2011-08-05 2013-02-14 Forsight Vision4, Inc. Administration de petites molécules à l'aide d'un dispositif thérapeutique implantable
PT105065B (pt) 2010-04-26 2012-07-31 Hovione Farmaciencia S A Um inalador simples de cápsulas
WO2012019139A1 (fr) 2010-08-05 2012-02-09 Forsight Vision4, Inc. Procédés et appareils d'administration combinée de médicament
HRP20211909T1 (hr) 2010-08-05 2022-03-18 Forsight Vision4, Inc. Uređaj za liječenja oka
CN105435338B (zh) 2010-08-05 2019-03-26 弗赛特影像4股份有限公司 用于药物输送的注入器装置和方法
US8689439B2 (en) 2010-08-06 2014-04-08 Abbott Laboratories Method for forming a tube for use with a pump delivery system
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
US8377000B2 (en) 2010-10-01 2013-02-19 Abbott Laboratories Enteral feeding apparatus having a feeding set
US8377001B2 (en) 2010-10-01 2013-02-19 Abbott Laboratories Feeding set for a peristaltic pump system
CA2818612C (fr) 2010-11-19 2020-12-29 Forsight Vision4, Inc. Formulations d'agents therapeutiques pour des dispositifs implantes
JOP20120023B1 (ar) 2011-02-04 2022-03-14 Novartis Ag صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية
US10398592B2 (en) 2011-06-28 2019-09-03 Forsight Vision4, Inc. Diagnostic methods and apparatus
DK2755600T3 (da) 2011-09-16 2021-05-03 Forsight Vision4 Inc Fluidudvekslingsindretning
WO2013116061A1 (fr) 2012-02-03 2013-08-08 Forsight Vision4, Inc. Procédés et instrument pour l'insertion et le retrait de dispositifs thérapeutiques
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
JP6363616B2 (ja) 2012-12-19 2018-07-25 ノバルティス アーゲー オートタキシン阻害剤
CA2905496A1 (fr) 2013-03-14 2014-09-25 Forsight Vision4, Inc. Systemes pour l'administration intra-oculaire entretenue de composes a faible solubilite provenant d'un implant de systeme de pose d'orifice
US9526654B2 (en) 2013-03-28 2016-12-27 Forsight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
SG11201600241RA (en) 2013-07-18 2016-02-26 Novartis Ag Autotaxin inhibitors comprising a heteroaromatic ring-benzyl-amide-cycle core
WO2015008229A1 (fr) 2013-07-18 2015-01-22 Novartis Ag Inhibiteurs de l'autotaxine
US20170037030A1 (en) 2014-04-24 2017-02-09 Novartis Ag Autotaxin inhibitors
KR102416726B1 (ko) 2014-07-15 2022-07-05 포사이트 비젼4, 인크. 안구 이식물 전달 디바이스 및 방법
SG11201700943TA (en) 2014-08-08 2017-03-30 Forsight Vision4 Inc Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
CN114587774B (zh) 2014-11-10 2024-07-19 弗赛特影像4股份有限公司 治疗眼睛的系统
JP6926063B2 (ja) * 2015-04-15 2021-08-25 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 乾燥粉末吸入器及び使用方法
WO2017087902A1 (fr) 2015-11-20 2017-05-26 Forsight Vision4, Inc. Structures poreuses pour dispositifs d'administration de médicament à libération prolongée
WO2017176886A1 (fr) 2016-04-05 2017-10-12 Forsight Vision4, Inc. Dispositifs implantables d'administration de médicaments par voie oculaire
EP3452170A4 (fr) * 2016-05-05 2020-04-01 Liquidia Technologies, Inc. Poudre sèche de tréprostinil pour le traitement de l'hypertension pulmonaire
WO2019103906A1 (fr) 2017-11-21 2019-05-31 Forsight Vision4, Inc. Appareil d'échange de fluide pour système d'administration à port extensible et méthodes d'utilisation
CN111834656B (zh) * 2020-07-25 2022-03-22 山东交通学院 一种优化的单相掺杂镓酸镧电解质制备装置及方法
USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device
WO2025096521A1 (fr) * 2023-10-30 2025-05-08 Insmed Incorporated Dispositif d'administration de médicament, couvercle et procédés d'administration de médicament

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888253A (en) * 1972-08-04 1975-06-10 Beecham Group Ltd Device for administration of medicines
WO1999039760A1 (fr) * 1998-02-05 1999-08-12 Unisia Jecs Corporation Inhalateur de medicaments
US6668827B2 (en) * 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
WO2006054021A2 (fr) * 2004-11-16 2006-05-26 Valois Sas Dispositif de distribution de produit fluide
WO2008051621A2 (fr) * 2006-10-25 2008-05-02 Novartis Ag Appareil de dispersion de poudre, procédé de fabrication et d'utilisation de l'appareil et composant pouvant être utilisé sur l'appareil et d'autres dispositifs

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888253A (en) * 1972-08-04 1975-06-10 Beecham Group Ltd Device for administration of medicines
WO1999039760A1 (fr) * 1998-02-05 1999-08-12 Unisia Jecs Corporation Inhalateur de medicaments
US6668827B2 (en) * 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
WO2006054021A2 (fr) * 2004-11-16 2006-05-26 Valois Sas Dispositif de distribution de produit fluide
WO2008051621A2 (fr) * 2006-10-25 2008-05-02 Novartis Ag Appareil de dispersion de poudre, procédé de fabrication et d'utilisation de l'appareil et composant pouvant être utilisé sur l'appareil et d'autres dispositifs

Also Published As

Publication number Publication date
WO2009117112A2 (fr) 2009-09-24
EP2257326A2 (fr) 2010-12-08

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