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WO2009152270A1 - Dispositif de fixation de fracture, outils et procédés - Google Patents

Dispositif de fixation de fracture, outils et procédés Download PDF

Info

Publication number
WO2009152270A1
WO2009152270A1 PCT/US2009/046949 US2009046949W WO2009152270A1 WO 2009152270 A1 WO2009152270 A1 WO 2009152270A1 US 2009046949 W US2009046949 W US 2009046949W WO 2009152270 A1 WO2009152270 A1 WO 2009152270A1
Authority
WO
WIPO (PCT)
Prior art keywords
bone
fixation device
elongate body
clavicle
gripper
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2009/046949
Other languages
English (en)
Inventor
Trung Ho Pham
Stephen R. Mcdaniel
Charles L. Nelson
Heber Saravia
Nathan Brown
Thomas R. Hackett
Lonnie Paulos
Robert G. Coleman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sonoma Orthopedic Products Inc
Original Assignee
Sonoma Orthopedic Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sonoma Orthopedic Products Inc filed Critical Sonoma Orthopedic Products Inc
Priority to PCT/US2009/046949 priority Critical patent/WO2009152270A1/fr
Publication of WO2009152270A1 publication Critical patent/WO2009152270A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary devices, e.g. pins or nails
    • A61B17/7233—Intramedullary devices, e.g. pins or nails with special means of locking the nail to the bone
    • A61B17/7258—Intramedullary devices, e.g. pins or nails with special means of locking the nail to the bone with laterally expanding parts, e.g. for gripping the bone
    • A61B17/7266—Intramedullary devices, e.g. pins or nails with special means of locking the nail to the bone with laterally expanding parts, e.g. for gripping the bone with fingers moving radially outwardly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/16—Instruments for performing osteoclasis; Drills or chisels for bones; Trepans
    • A61B17/17—Guides or aligning means for drills, mills, pins or wires
    • A61B17/1717—Guides or aligning means for drills, mills, pins or wires for applying intramedullary nails or pins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary devices, e.g. pins or nails
    • A61B17/7208—Flexible pins, e.g. ENDER pins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary devices, e.g. pins or nails
    • A61B17/7216—Intramedullary devices, e.g. pins or nails for bone lengthening or compression
    • A61B17/7225—Intramedullary devices, e.g. pins or nails for bone lengthening or compression for bone compression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary devices, e.g. pins or nails
    • A61B17/7291—Intramedullary devices, e.g. pins or nails for small bones, e.g. in the foot, ankle, hand or wrist
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/16—Instruments for performing osteoclasis; Drills or chisels for bones; Trepans
    • A61B17/17—Guides or aligning means for drills, mills, pins or wires
    • A61B17/1739—Guides or aligning means for drills, mills, pins or wires specially adapted for particular parts of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary devices, e.g. pins or nails
    • A61B17/7233—Intramedullary devices, e.g. pins or nails with special means of locking the nail to the bone
    • A61B17/7241—Intramedullary devices, e.g. pins or nails with special means of locking the nail to the bone the nail having separate elements through which screws pass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/06—Measuring instruments not otherwise provided for
    • A61B2090/062—Measuring instruments not otherwise provided for penetration depth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/08—Accessories or related features not otherwise provided for
    • A61B2090/0801—Prevention of accidental cutting or pricking
    • A61B2090/08021—Prevention of accidental cutting or pricking of the patient or his organs

Definitions

  • Osteoporosis and osteoarthritis occur in a substantial portion of the human population over the age of fifty.
  • the National Osteoporosis Foundation estimates that as many as 44 million Americans are affected by osteoporosis and low bone mass, leading to fractures in more than 300,000 people over the age of 65.
  • the estimated cost for osteoporosis related fractures was $13 billion. That figure increased to $ 17billion in 2002 and is projected to increase to $210-240 billion by 2040.
  • Osteoporosis is the most important underlying cause of fracture in the elderly.
  • a conventional IM nail procedure requires a similar, but possibly larger, opening to the space, a long metallic nail being placed across the fracture, and either subsequent removal, and or when the nail is not removed, a long term implant of the IM nail.
  • the outer diameter of the IM nail must be selected for the minimum inside diameter of the space. Therefore, portions of the IM nail may not be in contact with the canal. Further, micromotion between the bone and the IM nail may cause pain or necrosis of the bone. In still other cases, infection can occur.
  • the IM nail may be removed after the fracture has healed. This requires a subsequent surgery with all of the complications and risks of a later intrusive procedure.
  • the bone fixation device may include an elongate body with a longitudinal axis, having a flexible state and a rigid state.
  • the device further may include a plurality of grippers disposed at longitudinally-spaced locations along the elongated body, a rigid hub connected to the elongated body, and an actuator that is operably-connected to the grippers to deploy the grippers from a first shape to an expanded second shape.
  • the elongate body and the rigid hub may or may not be collinear or parallel.
  • a bone fixation device is provided with an elongate body having a longitudinal axis and having a first state in which at least a portion of the body is flexible and a second state in which the body is generally rigid, an actuatable bone engaging mechanism disposed on the elongate body, and an actuator operably connected to the bone engaging mechanism to actuate the bone engaging mechanism from a disengaged configuration to an engaged configuration.
  • Methods of repairing a fracture of a bone are also disclosed.
  • One such method comprises inserting a bone fixation device into an intramedullary space of the bone to place at least a portion of an elongate body of the fixation device in a flexible state on one side of the fracture and at least a portion of a hub on another side of the fracture, and operating an actuator to deploy at least one gripper of the fixation device to engage an inner surface of the intramedullary space to anchor the fixation device to the bone.
  • Another such method of repairing a fracture of a clavicle, the clavicle having a lateral segment adjacent to the acromion of a scapula and a medial segment adjacent to the manubrium of a sternum comprises creating an intramedullary channel, such that the channel traverses the fracture of the clavicle and comprises at least one segment that substantially follows a curved anatomical contour of the clavicle; and inserting a bone fixation device into the intramedullary channel and across the fracture of the clavicle, such that at least a portion of an elongate body of the fixation device in a flexible state is placed within the curved segment of the channel.
  • the method comprises creating an intramedullary channel, such that the channel traverses the fracture of the bone and comprises at least one segment that substantially follows a curved anatomical contour of the bone; and inserting a bone fixation device into the intramedullary channel and across the fracture of the bone, such that at least a portion of an elongate body of the fixation device in a flexible state is placed within the curved segment of the channel.
  • One embodiment of the present invention provides a low weight to volume mechanical support for fixation, reinforcement and reconstruction of bone or other regions of the musculoskeletal system in both humans and animals.
  • the method of delivery of the device is another aspect of the invention.
  • the method of delivery of the device in accordance with the various embodiments of the invention reduces the trauma created during surgery, decreasing the risks associated with infection and thereby decreasing the recuperation time of the patient.
  • the framework may in one embodiment include an expandable and contractible structure to permit re-placement and removal of the reinforcement structure or framework.
  • An aspect of the invention discloses a removable bone fixation device that uses a single port of insertion and has a single-end of remote actuation wherein a bone fixation device stabilizes bone after it has traversed the fracture.
  • the bone fixation device is adapted to provide a single end in one area or location where the device initiates interaction with bone.
  • the device can be deployed such that the device interacts with bone.
  • Single portal insertion and single-end remote actuation enables the surgeon to insert and deploy the device, deactivate and remove the device, reduce bone fractures, displace or compress the bone, and lock the device in place.
  • the single-end actuation enables the device to grip bone, compresses the rigidizable flexible body, permits axial, torsional and angular adjustments to its position during surgery, and releases the device from the bone during its removal procedure.
  • a removable extractor can be provided in some embodiments of the device to enable the device to be placed and extracted by deployment and remote actuation from a single end.
  • the device of the invention can be adapted and configured to provide at least one rigidizable flexible body or sleeve. Further the body can be configured to be flexible in all angles and directions. The flexibility provided is in selective planes and angles in the Cartesian, polar, or cylindrical coordinate systems. Further, in some embodiments, the body is configured to have a remote actuation at a single end.
  • the body can be configured to have apertures, windings, etc.
  • the device may be configured to function with non-flexible bodies for use in bones that have a substantially straight segment or curved segments with a constant radius of curvature.
  • Another aspect of the invention includes a bone fixation device in that has mechanical geometry that interacts with bone by a change in the size of at least one dimension of a Cartesian, polar, or spherical coordinate system.
  • bioabsorbable materials can be used in conjunction with the devices, for example by providing specific subcomponents of the device configured from bioabsorbable materials.
  • a sleeve can be provided in some embodiments where the sleeve is removable, has deployment, remote actuation, and a single end.
  • the sleeve can be adapted to provide a deployable interdigitation process or to provide an aperture along its length through which the deployable interdigitation process is adapted to engage bone.
  • the deployable interdigitation process is further adapted to engage bone when actuated by the sleeve.
  • the bone fixation device further comprises a cantilever adapted to retain the deployable bone fixation device within the space.
  • the sleeve can further be adapted to be expanded and collapsed within the space by a user.
  • One end of the device can be configured to provide a blunt obturator surface adapted to advance into the bone.
  • a guiding tip may also be provided that facilitates guiding the device through the bone.
  • Figure 1 depicts the skeletal system of the pectoral girdles.
  • Figure 2 show the superior surface of a left clavicle.
  • Figure 3 is a side view of an embodiment of a bone repair device constructed according to aspects of the invention.
  • Figure 4 shows the device of Figure 3 in a deployed state.
  • Figures 19 and 20 are a side view and a cross-section view, respectively, of an alternative embodiment.
  • a cannulated reaming tool or drill bit may be advanced into the bone over one of the guidewires described above.
  • the cannulated tool may be used to expand the diameter of the channel to a diameter large enough to accept the fixation device.
  • the cannulated tool may be stiff or flexible. For example, if the tool is flexible, it may be advanced over the guidewire and follow the curve of the channel to create a contoured and anatomically matching channel.
  • the cannulated tool may also function as a sheath or trocar-like device.
  • the cannulated tool may remain at least partially within the bone, and one or a series of guidewires may be inserted and removed through the cannulated tool.
  • the guidewire may be removed, and a tool (cannulated or not) may be moved through the bone independently.
  • a driver tool such as one with a hexagonal tip (not shown) may be inserted axially into the proximal end of the device until the tool tip is received within keyed socket 130' of drive member 128'.
  • the driver tool is axially rotated, threadably engaged drive member and the distal end of the actuator are drawn together such that they apply a compressive force to the flexible-to-rigid portion the elongate body along the longitudinal axis thereby changing the elongate body from its flexible state to its rigid state.
  • Figures 19 and 20 also show another alternative embodiment similar to device 100 described above.
  • Device 1900 like device 100, includes a distal gripper 108 and a proximal gripper 109.
  • a guide wire 1350 ( Figure 13) may be used to penetrate the bone prior to inserting device 100'.
  • a canulated reamer and/or drill can be used over the guide wire to create an intramedullary space for the device.
  • Device 100' can then be guided into place over guide wire 1350.
  • the intramedullary space may be prepared and device 100' inserted without the use of a guidewire.
  • the inventive implantable device, tools and methods may be used in many locations within the body.
  • the proximal end of a device in the anatomical context is the end closest to the body midline and the distal end in the anatomical context is the end further from the body midline, for example, on the humerus, at the head of the humerus (located proximal, or nearest the midline of the body) or at the lateral or medial epicondyle (located distal, or furthest away from the midline); on the radius, at the head of the radius (proximal) or the radial styloid process(distal); on the ulna, at the head of the ulna (proximal) or the ulnar styloid process (distal); for the femur, at the greater trochanter (proximal) or the lateral epicondyle or medial epicondyle (distal); for the tibia

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  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgical Instruments (AREA)

Abstract

Le dispositif de fixation osseuse selon l'invention comprend un corps allongé ayant un axe longitudinal et ayant un premier état où au moins une partie du corps est flexible et un second état où le corps est généralement rigide, un préhenseur actionnable agencé en un emplacement distal sur le corps allongé, et un actionneur connecté fonctionnellement au préhenseur pour déployer le préhenseur et le faire passer d'une configuration rétractée à une configuration expansée. Des procédés pour réparer une fracture osseuse sont également décrits. Un de ces procédés comprend l'insertion d'un dispositif de fixation osseuse dans un espace intramédullaire de l'os pour mettre au moins une partie d'un corps allongé du dispositif de fixation dans un état flexible d'un côté de la fracture et au moins une partie d'un corps d'un autre côté de la fracture, et l'actionnement d'un actionneur pour déployer au moins un préhenseur du dispositif de fixation pour qu'il vienne au contact d'une surface interne de l'espace intramédullaire afin d'ancrer le dispositif de fixation à l'os.
PCT/US2009/046949 2008-06-10 2009-06-10 Dispositif de fixation de fracture, outils et procédés Ceased WO2009152270A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2009/046949 WO2009152270A1 (fr) 2008-06-10 2009-06-10 Dispositif de fixation de fracture, outils et procédés

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US6044508P 2008-06-10 2008-06-10
US6045008P 2008-06-10 2008-06-10
US6044008P 2008-06-10 2008-06-10
US61/060,450 2008-06-10
US61/060,440 2008-06-10
US61/060,445 2008-06-10
US10065208P 2008-09-26 2008-09-26
US10063508P 2008-09-26 2008-09-26
US61/100,652 2008-09-26
US61/100,635 2008-09-26
US11790108P 2008-11-25 2008-11-25
US61/117,901 2008-11-25
US12256308P 2008-12-15 2008-12-15
US61/122,563 2008-12-15
US13892008P 2008-12-18 2008-12-18
US61/138,920 2008-12-18
PCT/US2009/046949 WO2009152270A1 (fr) 2008-06-10 2009-06-10 Dispositif de fixation de fracture, outils et procédés

Publications (1)

Publication Number Publication Date
WO2009152270A1 true WO2009152270A1 (fr) 2009-12-17

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PCT/US2009/046949 Ceased WO2009152270A1 (fr) 2008-06-10 2009-06-10 Dispositif de fixation de fracture, outils et procédés

Country Status (1)

Country Link
WO (1) WO2009152270A1 (fr)

Cited By (31)

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WO2012107913A2 (fr) 2011-02-13 2012-08-16 Carbofix Orthopedics Ltd. Implant osseux transparent flexible
US8287538B2 (en) 2008-01-14 2012-10-16 Conventus Orthopaedics, Inc. Apparatus and methods for fracture repair
WO2013063145A1 (fr) * 2011-10-28 2013-05-02 Sonoma Orthopedic Products, Inc. Dispositifs de fixation de fracture intramédullaire segmentés
US8709055B2 (en) 2009-01-16 2014-04-29 Carbofix Orthopedics Ltd. Composite material bone implant
US8906022B2 (en) 2010-03-08 2014-12-09 Conventus Orthopaedics, Inc. Apparatus and methods for securing a bone implant
US8961518B2 (en) 2010-01-20 2015-02-24 Conventus Orthopaedics, Inc. Apparatus and methods for bone access and cavity preparation
CN104783881A (zh) * 2015-05-20 2015-07-22 陈伟 一种锁骨骨折微创髓内固定装置
US9101427B2 (en) 2010-06-07 2015-08-11 Carbofix Orthopedics Ltd. Self tapping insert
EP2990002A1 (fr) * 2014-09-01 2016-03-02 Wittenstein AG Clou medullaire
US9351771B2 (en) 2013-02-08 2016-05-31 Robert Gorsline Systems, methods, and apparatuses for fusion, stabilization, or fixation of bones
US9526549B2 (en) 2012-01-16 2016-12-27 Carbofix Orthopedics Ltd. Bone screw with insert
US9603907B2 (en) 2012-02-01 2017-03-28 Protalix Ltd. Dry powder formulations of dNase I
US9730739B2 (en) 2010-01-15 2017-08-15 Conventus Orthopaedics, Inc. Rotary-rigid orthopaedic rod
US9855063B2 (en) 2013-02-28 2018-01-02 Jonathan Feibel Systems, methods, and apparatuses for reaming bone elements
US10022132B2 (en) 2013-12-12 2018-07-17 Conventus Orthopaedics, Inc. Tissue displacement tools and methods
US10039556B2 (en) 2011-11-10 2018-08-07 David Michael Burt Arthroscopic total shoulder arthroplasty
US10136929B2 (en) 2015-07-13 2018-11-27 IntraFuse, LLC Flexible bone implant
US10154867B2 (en) 2010-06-07 2018-12-18 Carbofix In Orthopedics Llc Multi-layer composite material bone screw
US10154863B2 (en) 2015-07-13 2018-12-18 IntraFuse, LLC Flexible bone screw
EP3419535A4 (fr) * 2016-02-26 2019-10-09 Activortho, Inc. Appareil de compression active, procédés d'assemblage et procédés d'utilisation
US10485595B2 (en) 2015-07-13 2019-11-26 IntraFuse, LLC Flexible bone screw
US10499960B2 (en) 2015-07-13 2019-12-10 IntraFuse, LLC Method of bone fixation
US10617458B2 (en) 2015-12-23 2020-04-14 Carbofix In Orthopedics Llc Multi-layer composite material bone screw
US10729478B1 (en) * 2019-11-22 2020-08-04 Retrofix Screws, Llc Cannulated orthopedic screw and method of reducing a fracture of the lateral malleolus
CN111670016A (zh) * 2017-12-04 2020-09-15 艾缇沃托公司 主动压缩装置，组装方法和使用方法
US10918426B2 (en) 2017-07-04 2021-02-16 Conventus Orthopaedics, Inc. Apparatus and methods for treatment of a bone
US10952780B1 (en) 2019-11-22 2021-03-23 Retrofix Screws, Llc Method of reducing a fracture of the lateral malleolus
US11224467B2 (en) 2016-02-26 2022-01-18 Activortho, Inc. Active compression apparatus, methods of assembly and methods of use
WO2022051016A1 (fr) * 2020-06-26 2022-03-10 Retrofix Screws, Llc Procédé de réduction d'une fracture de la malléole latérale
US11857236B1 (en) 2023-06-05 2024-01-02 Retrofix Screws, Llc Orthopedic screw
CN118303961A (zh) * 2024-03-25 2024-07-09 中国人民解放军总医院第四医学中心 一种弹性髓内固定装置

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Cited By (52)

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Publication number Priority date Publication date Assignee Title
US9060820B2 (en) 2005-05-18 2015-06-23 Sonoma Orthopedic Products, Inc. Segmented intramedullary fracture fixation devices and methods
US8287538B2 (en) 2008-01-14 2012-10-16 Conventus Orthopaedics, Inc. Apparatus and methods for fracture repair
US9517093B2 (en) 2008-01-14 2016-12-13 Conventus Orthopaedics, Inc. Apparatus and methods for fracture repair
US10603087B2 (en) 2008-01-14 2020-03-31 Conventus Orthopaedics, Inc. Apparatus and methods for fracture repair
US9788870B2 (en) 2008-01-14 2017-10-17 Conventus Orthopaedics, Inc. Apparatus and methods for fracture repair
US11399878B2 (en) 2008-01-14 2022-08-02 Conventus Orthopaedics, Inc. Apparatus and methods for fracture repair
US8709055B2 (en) 2009-01-16 2014-04-29 Carbofix Orthopedics Ltd. Composite material bone implant
US9101417B2 (en) 2009-01-16 2015-08-11 Carbofix Orthopedics Ltd. Composite material bone implant
US10028777B2 (en) 2009-01-16 2018-07-24 Carbofix Orthopedics Ltd. Composite material bone implant
US9730739B2 (en) 2010-01-15 2017-08-15 Conventus Orthopaedics, Inc. Rotary-rigid orthopaedic rod
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