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WO2009001915A1 - Substituted imidazole compound and use thereof - Google Patents

Substituted imidazole compound and use thereof Download PDF

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Publication number
WO2009001915A1
WO2009001915A1 PCT/JP2008/061693 JP2008061693W WO2009001915A1 WO 2009001915 A1 WO2009001915 A1 WO 2009001915A1 JP 2008061693 W JP2008061693 W JP 2008061693W WO 2009001915 A1 WO2009001915 A1 WO 2009001915A1
Authority
WO
WIPO (PCT)
Prior art keywords
substituted imidazole
imidazole compound
formula
disclosed
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/061693
Other languages
French (fr)
Japanese (ja)
Inventor
Takanobu Kuroita
Yoshiyuki Fukase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Publication of WO2009001915A1 publication Critical patent/WO2009001915A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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Abstract

Disclosed is a novel substituted imidazole compound having excellent renin inhibitory activity, which is sufficiently practical for use as a pharmaceutical product. Specifically disclosed is a compound represented by the formula (I) below or a salt thereof. (In the formula, the symbols are as defined in the description.)
PCT/JP2008/061693 2007-06-28 2008-06-27 Substituted imidazole compound and use thereof Ceased WO2009001915A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007-171244 2007-06-28
JP2007171244 2007-06-28
JP2007-207096 2007-08-08
JP2007207096 2007-08-08

Publications (1)

Publication Number Publication Date
WO2009001915A1 true WO2009001915A1 (en) 2008-12-31

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US8329691B2 (en) 2007-10-15 2012-12-11 Takeda Pharmaceutical Company Limited Amide compounds and use of the same
US8466282B2 (en) 2008-06-19 2013-06-18 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof

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JP2006528677A (en) * 2003-01-31 2006-12-21 バーテックス　ファーマシューティカルズ　インコーポレイテッド Gyrase inhibitor and use thereof
WO2007120718A2 (en) * 2006-04-14 2007-10-25 Merck & Co., Inc. Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators

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JP2004518684A (en) * 2000-12-15 2004-06-24 バーテックス　ファーマシューティカルズ　インコーポレイテッド Bacterial gyrase inhibitors and uses thereof
JP2006528677A (en) * 2003-01-31 2006-12-21 バーテックス　ファーマシューティカルズ　インコーポレイテッド Gyrase inhibitor and use thereof
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8329691B2 (en) 2007-10-15 2012-12-11 Takeda Pharmaceutical Company Limited Amide compounds and use of the same
US8466282B2 (en) 2008-06-19 2013-06-18 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
US8664380B2 (en) 2008-06-19 2014-03-04 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
US9045436B2 (en) 2008-06-19 2015-06-02 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
US9221836B2 (en) 2008-06-19 2015-12-29 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof

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