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WO2009084023A3 - Amorphous ramelteon and process for the preparation thereof - Google Patents

Amorphous ramelteon and process for the preparation thereof Download PDF

Info

Publication number
WO2009084023A3
WO2009084023A3 PCT/IN2008/000679 IN2008000679W WO2009084023A3 WO 2009084023 A3 WO2009084023 A3 WO 2009084023A3 IN 2008000679 W IN2008000679 W IN 2008000679W WO 2009084023 A3 WO2009084023 A3 WO 2009084023A3
Authority
WO
WIPO (PCT)
Prior art keywords
ramelteon
amorphous
preparation
dissolving
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2008/000679
Other languages
French (fr)
Other versions
WO2009084023A2 (en
Inventor
Khan Mubeen Ahmed
Arvindbhai Patel Dharmesh Kumar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glenmark Generics Ltd
Original Assignee
Glenmark Generics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Generics Ltd filed Critical Glenmark Generics Ltd
Publication of WO2009084023A2 publication Critical patent/WO2009084023A2/en
Anticipated expiration legal-status Critical
Publication of WO2009084023A3 publication Critical patent/WO2009084023A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

The present invention provides ramelteon substantially in an amorphous form and a process for its preparation, by preparing solution of ramelteon by dissolving in one or more solvents capable of dissolving the ramelteon; and substantially removing the solvent from the solution to provide amorphous ramelteon
PCT/IN2008/000679 2007-10-19 2008-10-16 Amorphous ramelteon and process for the preparation thereof Ceased WO2009084023A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2081MU2007 2007-10-19
IN2081/MUM/2007 2007-10-19

Publications (2)

Publication Number Publication Date
WO2009084023A2 WO2009084023A2 (en) 2009-07-09
WO2009084023A3 true WO2009084023A3 (en) 2011-09-22

Family

ID=40824838

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2008/000679 Ceased WO2009084023A2 (en) 2007-10-19 2008-10-16 Amorphous ramelteon and process for the preparation thereof

Country Status (1)

Country Link
WO (1) WO2009084023A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008151170A2 (en) 2007-05-31 2008-12-11 Teva Pharmaceutical Industries Ltd. Process for the synthesis of ramelteon and its intermediates
WO2011009102A1 (en) * 2009-07-16 2011-01-20 Vanda Pharmaceuticals Inc. Use of a melatonin agonist for the treatment of sleep disorders including primary insomnia
US11918557B2 (en) 2012-01-26 2024-03-05 Vanda Pharmaceuticals Inc. Treatment of circadian rhythm disorders
WO2013112949A2 (en) 2012-01-26 2013-08-01 Vanda Pharmaceuticals Inc. Treatment of circadian rhythm disorders
BR112015014619A2 (en) 2012-12-18 2017-07-11 Vanda Pharmaceuticals Inc treatment of circadian rhythm disorders
US11090285B2 (en) 2013-11-12 2021-08-17 Vanda Pharmaceuticals Inc Treatment of circadian rhythm disorders
US10376487B2 (en) 2013-11-12 2019-08-13 Vanda Pharmaceuticals Inc. Method of treatment
JP7407364B2 (en) * 2019-02-12 2024-01-04 日本ジェネリック株式会社 Ramelteon-containing solid preparation
WO2025211383A1 (en) * 2024-04-03 2025-10-09 株式会社ダイセル Functional material containing 8-prenylnaringenin, oral composition, food and drink, atrogin-1 expression inhibitor, and functional material composition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2612090A1 (en) * 2005-06-22 2006-12-28 Takeda Pharmaceutical Company Limited Tablet containing hardly soluble active ingredient
WO2007020337A1 (en) * 2005-08-19 2007-02-22 Sanofi-Aventis Combination of a long-acting hypnotic agent and a short-acting hypnotic agent and therapeutic use of same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2612090A1 (en) * 2005-06-22 2006-12-28 Takeda Pharmaceutical Company Limited Tablet containing hardly soluble active ingredient
WO2007020337A1 (en) * 2005-08-19 2007-02-22 Sanofi-Aventis Combination of a long-acting hypnotic agent and a short-acting hypnotic agent and therapeutic use of same

Also Published As

Publication number Publication date
WO2009084023A2 (en) 2009-07-09

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