WO2009084069A4 - Ocular solution with organic lycopene - Google Patents
Ocular solution with organic lycopene Download PDFInfo
- Publication number
- WO2009084069A4 WO2009084069A4 PCT/IT2008/000793 IT2008000793W WO2009084069A4 WO 2009084069 A4 WO2009084069 A4 WO 2009084069A4 IT 2008000793 W IT2008000793 W IT 2008000793W WO 2009084069 A4 WO2009084069 A4 WO 2009084069A4
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compositions according
- derivatives
- hyaluronic acid
- weight
- lycopene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Topical ocular solution comprising carotenoids, liposomes, plant lipids/cerasomes, phospholipids and viscosifying agents.
Claims
AMENDED CLAIMS [received by the International Bureau on 14 September 2009 (14.09.2009)]
1) Topical ocular compositions comprising organic antioxidant agents such as carotenoids, cerasomes, plant lipids and viscosifying agents.
2) Compositions according to claim 1, wherein the carotenoids comprise organic lycopene.
3) Compositions according to claim 2, wherein the lycopene is present in concentrations in the range of 0.01% - 0.5% by weight.
4) Compositions according to claim 2 or 3, characterised in that they protect from UVA/UVB radiations.
5) Compositions according to one of the preceding claims, characterised in that it contains linear and/or cross-linked hyaluronic acid and/or its salts with moistening and lubricating effect, as well as viscosifying agent.
6) Compositions according to claim 5, wherein the hyaluronic acid is present in concentrations in the range of 0.001% - 10% by weight.
7) Compositions according to claim 5 or 6, wherein the hyaluronic acid has a molecular weight from 200 kDalton to 30 MDalton.
8) Compositions according to one of the claims from 1 to 4, containing viscoelastic substances such as polyvinyl alcohol and derivatives, polyvinylpyrrolidone and derivatives, hydroxypropylmethylcellulose and derivatives,
carboxymethylcellulose and its derivatives, polyacrylic acids, xanthan and its derivatives, beta glucan and its derivatives, on their own or mixed with hyaluronic acid or its salts.
9) Compositions according to one of the preceding claims, wherein the plant lipids are present in concentrations in the range of 0.001% - 4% by weight.
10) Compositions according to one of the preceding claims, also comprising other antioxidant agents selected from among Vitamin A, Vitamin E, Vitamin C, Resveratrol, honey, royal jelly, antibiotics, anti-inflammatory agents, cortisones, extracts of Aloe vera and the like, all of them being synergic.
11) Compositions according to one of the preceding claims, characterised by the presence of a buffer solution.
12) Compositions according to one of the preceding claims, wherein said buffer solution is citrate, phosphate or borate.
13) Compositions according to one of the preceding claims, for use as adjuvant in the treatment of Age-related Macular Degeneration, diabetic and hypertensive retinopathy, cornea repairing/cicatrising processes, degenerative processes of the eye surface and as carriers, stabilisers and preservatives for active ingredients.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000003A ITMI20080003A1 (en) | 2008-01-02 | 2008-01-02 | COMPOSITIONS FOR OPHTHALMIC USE |
| ITMI2008A000003 | 2008-01-02 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| WO2009084069A2 WO2009084069A2 (en) | 2009-07-09 |
| WO2009084069A3 WO2009084069A3 (en) | 2009-09-17 |
| WO2009084069A4 true WO2009084069A4 (en) | 2009-11-05 |
Family
ID=40290036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IT2008/000793 Ceased WO2009084069A2 (en) | 2008-01-02 | 2008-12-23 | Ocular solution with organic lycopene |
Country Status (2)
| Country | Link |
|---|---|
| IT (1) | ITMI20080003A1 (en) |
| WO (1) | WO2009084069A2 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3085365A3 (en) * | 2009-01-19 | 2017-01-04 | Lycored Ltd. | Synergistic combinations of carotenoids and polyphenols |
| US8802075B2 (en) | 2009-02-18 | 2014-08-12 | Eyeon Particle Sciences Llc | Bi-functional co-polymer use for opthalmic and other topical and local applications |
| WO2011138228A1 (en) * | 2010-05-04 | 2011-11-10 | Trb Chemedica Ag | Aqueous composition for ophthalmic or dermal use |
| ITMI20110849A1 (en) * | 2011-05-13 | 2012-11-14 | Farmila Thea Farmaceutici Spa | OPHTHALMIC PREPARATIONS IN THE FORM OF COLLIRIUM AND THEIR USE |
| WO2013096173A1 (en) * | 2011-12-21 | 2013-06-27 | Novartis Ag | Contact lenses containing carotenoid and method for making same |
| US9173915B1 (en) * | 2014-10-10 | 2015-11-03 | Peter F. Kador | Antioxidant eye drops |
| JP2017538728A (en) * | 2014-12-19 | 2017-12-28 | ケミン、インダストリーズ、インコーポレーテッドＫｅｍｉｎ Ｉｎｄｕｓｔｒｉｅｓ， Ｉｎｃ． | Intraocular delivery of bioactive molecules using iontophoresis |
| CA3029391C (en) | 2016-07-06 | 2024-01-02 | Eyeon Particle Sciences Llc | Bi-functional co-polymer use for ophthalmic and other topical and local applications |
| TW202027733A (en) * | 2019-01-16 | 2020-08-01 | 臺北醫學大學 | Lutein-containing ophthalmic composition |
| US11754753B2 (en) * | 2020-04-27 | 2023-09-12 | Coopervision International Limited | Antioxidant contact lens |
| RU2745124C1 (en) * | 2020-07-02 | 2021-03-22 | Общество с ограниченной ответственностью "МедикалСайнс" | Bioactive composition based on a crosslinked hyaluronic acid salt containing resveratrol and a method of its preparation |
| IT202100006839A1 (en) * | 2021-03-22 | 2022-09-22 | Omisan Farm S R L | WATER-SOLUBLE OPHTHALMIC TOPICAL PREPARATION CONTAINING LUTEIN AND RELATED PRODUCTION METHOD |
| EP4218717A1 (en) | 2022-02-01 | 2023-08-02 | Laboratoires THEA | Ophthalmic composition comprising resveratrol for treating dry eye syndrome |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0391909B1 (en) * | 1987-09-03 | 1994-08-17 | The University Of Georgia Research Foundation, Inc. | Ocular cyclosporin composition |
| US5596011A (en) * | 1995-04-06 | 1997-01-21 | Repine; Karen M. | Method for the treatment of macular degeneration |
| US6573299B1 (en) * | 1999-09-20 | 2003-06-03 | Advanced Medical Instruments | Method and compositions for treatment of the aging eye |
| US20050065091A1 (en) * | 2003-09-18 | 2005-03-24 | Gholam Peyman | Stabilized ocular solutions |
| FR2895257A1 (en) * | 2005-12-22 | 2007-06-29 | Oreal | ACTIVE FOR THE TREATMENT OF EYE CONTOUR. |
-
2008
- 2008-01-02 IT IT000003A patent/ITMI20080003A1/en unknown
- 2008-12-23 WO PCT/IT2008/000793 patent/WO2009084069A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009084069A3 (en) | 2009-09-17 |
| ITMI20080003A1 (en) | 2009-07-03 |
| WO2009084069A2 (en) | 2009-07-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2009084069A4 (en) | Ocular solution with organic lycopene | |
| US20070207116A1 (en) | Antioxidant compositions for the eye | |
| EP3017808B1 (en) | Water-soluble hyaluronic acid gel and method for producing same | |
| EP3713540B1 (en) | Plant based oil-in-water oral emulsions and methods of use | |
| EP3355848B1 (en) | Alcohol-based skin sanitizer having microbicidal properties | |
| EP2775838B1 (en) | Aqueous antimicrobial composition containing coniferous resin acids | |
| ES2689740T3 (en) | Topical composition without preservative comprising hyaluronic acid | |
| DE102014116903A1 (en) | Cineole-containing composition for nasal administration | |
| JP2021006518A (en) | Ophthalmic product with antioxidative function | |
| EP1883391B1 (en) | Epidermal growth factor composition, a process therefor and its application | |
| KR20210114438A (en) | Pharmaceutical delivery compositions and uses thereof | |
| CA2937213A1 (en) | Composition comprising xylitol and cholecalciferol for topical treatment of skin and mucous membranes | |
| US9364512B1 (en) | Aloe vera based vaping compositions | |
| CN102342890B (en) | Oil-in-water (O/W) skin protecting emulsion and preparation method thereof | |
| CN112237559A (en) | Disinfecting composition and preparation method thereof | |
| JP2009203184A (en) | Anti-aging cosmetic composition | |
| US20190365676A1 (en) | Oral compositoins and methods of use | |
| EP2552195B1 (en) | Antimicrobial oil-in-water emulsion | |
| CN103800939B (en) | A kind of antibacterial healing functional dressing and preparation method thereof | |
| US9931428B2 (en) | Ophthalmic compositions | |
| NZ596035A (en) | METHOD AND COMPOSITION FOR TREATING MACULAR DEGENERATION using 15-keto-prostaglandin such as 13,14-dihydro-15-keto-20-ethyl-prostagladin F2-alpha isopropyl ester | |
| WO2020241681A1 (en) | Antibacterial composition | |
| AU2015294663B2 (en) | Composition comprising an ester of alpha-tocopherol for prevention and treatment of allergic rhinitis | |
| CN114886788A (en) | A wet towel containing thymol and its preparation method | |
| KR102831184B1 (en) | Cosmetic composition containing sodium hexametaphosphate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NENP | Non-entry into the national phase in: |
Ref country code: DE |
|
| WPC | Withdrawal of priority claims after completion of the technical preparations for international publication |
Ref document number: MI2008A000003 Country of ref document: IT Date of ref document: 20100701 Free format text: WITHDRAWN AFTER TECHNICAL PREPARATION FINISHED |
|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 08868584 Country of ref document: EP Kind code of ref document: A2 |
|
| 122 | Ep: pct application non-entry in european phase |
Ref document number: 08868584 Country of ref document: EP Kind code of ref document: A2 |