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WO2009075334A1 - Uterine fibroid cell growth inhibitor, and prophylactic or therapeutic agent for uterine fibroid comprising the inhibitor - Google Patents

Uterine fibroid cell growth inhibitor, and prophylactic or therapeutic agent for uterine fibroid comprising the inhibitor Download PDF

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Publication number
WO2009075334A1
WO2009075334A1 PCT/JP2008/072571 JP2008072571W WO2009075334A1 WO 2009075334 A1 WO2009075334 A1 WO 2009075334A1 JP 2008072571 W JP2008072571 W JP 2008072571W WO 2009075334 A1 WO2009075334 A1 WO 2009075334A1
Authority
WO
WIPO (PCT)
Prior art keywords
uterine fibroid
inhibitor
cell growth
prophylactic
therapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/072571
Other languages
French (fr)
Japanese (ja)
Inventor
Takashi Takeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Osaka NUC
Original Assignee
Osaka University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osaka University NUC filed Critical Osaka University NUC
Publication of WO2009075334A1 publication Critical patent/WO2009075334A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The object aims to provide: a uterine fibroid cell growth inhibitor which is free from the risk of causing an adverse side effect including ovarian dysfunction and bone loss, and which can be administered over a long period; and a prophylactic or therapeutic agent for uterine fibroid. Disclosed are: a uterine fibroid cell growth inhibitor comprising an aldosterone receptor inhibitor as an active ingredient; and a prophylactic or therapeutic agent for uterine fibroid, which comprises the uterine fibroid cell growth inhibitor.
PCT/JP2008/072571 2007-12-12 2008-12-11 Uterine fibroid cell growth inhibitor, and prophylactic or therapeutic agent for uterine fibroid comprising the inhibitor Ceased WO2009075334A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-321299 2007-12-12
JP2007321299A JP2011037713A (en) 2007-12-12 2007-12-12 Uterine myoma cell growth inhibitor and prophylactic or therapeutic agent for uterine myoma comprising the same

Publications (1)

Publication Number Publication Date
WO2009075334A1 true WO2009075334A1 (en) 2009-06-18

Family

ID=40755573

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/072571 Ceased WO2009075334A1 (en) 2007-12-12 2008-12-11 Uterine fibroid cell growth inhibitor, and prophylactic or therapeutic agent for uterine fibroid comprising the inhibitor

Country Status (2)

Country Link
JP (1) JP2011037713A (en)
WO (1) WO2009075334A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011029782A1 (en) 2009-09-11 2011-03-17 Bayer Schering Pharma Aktiengesellschaft Substituted (heteroarylmethyl) thiohydantoins as anticancer drugs

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AKIRA ISOBE ET AL.: "Aldosterone ni yoru Shikyu Kinshu Saibo Zoshoku Sayo no Kento", ACTA OBSTETRICA ET GYNAECOLOGICA JAPONICA, vol. 60, no. 2, February 2008 (2008-02-01), pages 784 *
SATOH, T. ET AL.: "On the inhibitory action of 29 drugs having side effect gynecomastia on estrogen production", J STEROID BIOCHEM MOL BIOL, vol. 82, no. 2-3, 2002, pages 209 - 16 *
YUMIKO NISHIDA: "Shikyu Kinshu Kanja no Shinkekko Dotai ni Kansuru Rinshoteki Kenkyu Tokuni Hinketsu o Gappei shinai Kanja no Jutsumae Jutsugo Henka", JOURNAL OF THE MEDICAL SOCIETY OF TOHO UNIVERSITY, vol. 28, no. 5/6, 1981, pages 831 - 845 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011029782A1 (en) 2009-09-11 2011-03-17 Bayer Schering Pharma Aktiengesellschaft Substituted (heteroarylmethyl) thiohydantoins as anticancer drugs

Also Published As

Publication number Publication date
JP2011037713A (en) 2011-02-24

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