WO2009060486A1 - Method for drawing in a liquid product from a bottle by means of a syringe - Google Patents
Method for drawing in a liquid product from a bottle by means of a syringe Download PDFInfo
- Publication number
- WO2009060486A1 WO2009060486A1 PCT/IT2007/000791 IT2007000791W WO2009060486A1 WO 2009060486 A1 WO2009060486 A1 WO 2009060486A1 IT 2007000791 W IT2007000791 W IT 2007000791W WO 2009060486 A1 WO2009060486 A1 WO 2009060486A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- bottle
- product
- cannula
- closing membrane
- syringe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/162—Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2072—Venting means for internal venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2075—Venting means for external venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/162—Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
- A61M2005/1623—Details of air intake
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/1782—Devices aiding filling of syringes in situ
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
Definitions
- the present invention relates to a method for drawing in a liquid product from a bottle using a syringe.
- the present invention finds particularly advantageous application in drawing in liquid pharmaceutical products, to • which the following description will make explicit reference, without loosing generality.
- Figures 1-4 are schematic illustrations, in side elevation, of four different operating steps of a preferred embodiment of the method of the present invention.
- the bottle 2 has a given longitudinal axis 4 ' and is closed, at an open end thereof, by a perforable elastic membrane 5, whilst the syringe 3 has a given longitudinal axis 6 and comprises a containment cylinder 7, a piston 8 slidably engaged in the cylinder 7, and a suction needle 9 engaged to the cylinder 7 itself.
- the needle 9 comprises an engagement element 10, which is connected to the cylinder 7, and is provided with a- plurality of air-relief channels 11, which extend parallel to the axis 6, are uniformly distributed about the axis 6, and are made on an outer surface of the element 10 itself.
- the needle 9 moreover comprises a suction cannula 12 fitted on the element 10 parallel to the axis 6.
- drawing in the pharmaceutical product from the bottle 2 is performed by setting- the bottle 2 with the membrane 5 facing downwards, orienting the axis 4 of the bottle 2 parallel to a direction 13 set according to an angle different from 0° with respect to a substantially vertical direction 14, setting the syringe 3 with the needle 9 facing upwards, orienting the axis 6 of the syringe 3 according to an angle different from 0° with respect to the direction 14, in the case in point parallel to the direction 13, and displacing the bottle 2 and the syringe 3 with respect to one another in the direction 13 at a relatively high speed to enable the cannula 12 to perforate the membrane ' 5.
- the speed of perforation of the membrane 5 is in any case higher than the average speed normally used for displacing the syringe 3 and for displacing the cylinder 7 and the piston 8 with respect to one another.
- the inclination of the axes 4 and 6 with respect to the vertical direction 14 and the relatively high speed of perforation of the membrane 5 guarantee a relatively high seal between the cannula 12 and the membrane 5 itself and enable prevention of dripping and leakage of pharmaceutical product from the bottle 2.
- the inclination of the axes 4 and 6 with respect to the vertical direction 14 moreover enables orientation of possible air bubbles present within the bottle 2 along a path substantially parallel to the direction 14 and . hence prevention of their suction into the needle 9 and the cylinder 7.
- the piston 8 is displaced along the cylinder 7 so as to enable the needle 9 to draw in a first amount of pharmaceutical product from the bottle 2.
- the pressure within the bottle 2 decreases so as to be, at the. end of the first suction step, lower than the pressure within the cylinder 7.
- the bottle 2 and the syringe 3 are then displaced with respect to one another in the direction 13 so . as to enable the element 10 to traverse the membrane 5 and enable the channels 11 to connect the inside of the bottle 2 to the external environment .
- drawing in the second amount of pharmaceutical product from the bottle 2 must be interrupted at the latest when the level of the pharmaceutical product in the bottle 2 substantially corresponds to an inlet hole (not illustrated) of the cannula 12 so as to prevent the needle 9 from sucking air into the cylinder 7.
- the bottle 2 and the syringe 3 are displaced with respect to one another in the direction 13 for disengaging the element 10 again from the membrane 5, the cannula 12 is kept inside the bottle 2, the axis 4 of the bottle 2 is oriented parallel to the direction 14, and the axis 6 of the syringe 3 is kept parallel to the direction 13.
- the piston 8 is displaced again along the cylinder 7 to enable the needle 9 to draw in a third amount of pharmaceutical product from the bottle 2.
- the orientation of the axes 4 and 6 enables guaranteeing of a high seal between the membrane 5 and the cannula 12 and hence prevention of dripping and leakage of pharmaceutical product from the bottle 2.
- drawing-in of the third amount of pharmaceutical product from the bottle 2 must be interrupted at the latest., when the level of the pharmaceutical product in the bottle 2 substantially corresponds to the aforesaid inlet hole (not illustrated) of the cannula 12 so as to prevent the needle 9 from sucking air into the cylinder 7.
- the axis 4 of the bottle 2 is oriented again parallel to the direction 13 , the axis 6 of the syringe 3 is kept parallel to the direction 13 , and the bottle 2 and the syringe 3 are displaced with respect to one another in the direction 13 with a relatively low speed for disengaging the cannula 12 from the membrane 5 and from the bottle 2.
- the relatively low speed of extraction of the cannula 12 from the membrane 5, which is in any case lower than the speed of perforation of the membrane 5 itself, enables the bottle 2 to be set in communication with the external environment so as to bring about ah increase in the pressure within the bottle 2 up to a value substantially equal to atmospheric pressure.
- the piston 8 is displaced again along the cylinder 7 to draw the pharmaceutical product contained in the needle 9 into the cylinder 7, thus preventing any possible dripping of pharmaceutical product from the needle 9 itself.
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Drawing in a liquid product from a bottle (2) is performed by means of a syringe (3) provided with a needle (9) defined by a suction cannula (12) fitted on an engagement element (10) having at least one air-relief channel (11), and envisages perforation of a membrane (5) for closing the bottle (2), keeping the bottle (2) and the syringe (3) inclined with respect to a vertical reference direction (14), and drawing in the liquid product according to at least three distinct suction steps, in which the air-relief channel (11) is displaced, respectively, outside, inside, and again outside the bottle (2).
Description
"METHOD FOR DRAWING IN A LIQUID PRODUCT FROM A BOTTLE BY MEANS OF A SYRINGE"
TECHNICAL FIELD The present invention relates to a method for drawing in a liquid product from a bottle using a syringe.
The present invention- finds particularly advantageous application in drawing in liquid pharmaceutical products, to • which the following description will make explicit reference, without loosing generality.
BACKGROUND ART
For drawing in a pharmaceutical product from a bottle provided with a perforable closing membrane, it is known to set the bottle in a substantially vertical upside-down position and to draw in a given amount of pharmaceutical product by means of a syringe set in a substantially vertical position, with a suction needle thereof facing upwards .
The known methodology of drawing in a liquid product of the type described above presents some drawbacks principally deriving from the fact that the vertical orientation of the bottle and- of the syringe can lead, following upon perforation of the closing- membrane, . both to. dripping,, and hence leakage of pharmaceutical product from the bottle, and to imprecise dosage of the pharmaceutical product within the syringe caused by phenomena of cavitation and/or by phenomena of suction within the needle, and hence within the syringe, of air bubbles present inside the bottle.
DISCLOSURE OF INVENTION '
It is ' an object of the present invention to provide a method for drawing in a liquid product from a bottle by means of a syringe that will be free from the drawbacks described above and that will be simple and economically advantageous to
produce .
According to the present invention there is provided a method for drawing in a liquid product from a bottle by means' of a syringe according to what is claimed in the annexed claims .
BRIEF DESCRIPTION OF THE DRAWINGS
The present invention will now be- described with reference to the annexed drawings, which illustrates a non-limiting example of embodiment thereof and in which:
Figures 1-4 are schematic illustrations, in side elevation, of four different operating steps of a preferred embodiment of the method of the present invention.
BEST MODE FOR CARRYING OUT THE INVENTION
With reference to Figures 1-4, designated as a whole by 1 is a station for drawing in a pharmaceutical liquid product from a bottle 2 by means of a syringe 3.
The bottle 2 has a given longitudinal axis 4 ' and is closed, at an open end thereof, by a perforable elastic membrane 5, whilst the syringe 3 has a given longitudinal axis 6 and comprises a containment cylinder 7, a piston 8 slidably engaged in the cylinder 7, and a suction needle 9 engaged to the cylinder 7 itself.
The needle 9 comprises an engagement element 10, which is connected to the cylinder 7, and is provided with a- plurality of air-relief channels 11, which extend parallel to the axis 6, are uniformly distributed about the axis 6, and are made on an outer surface of the element 10 itself. The needle 9 moreover comprises a suction cannula 12 fitted on the element 10 parallel to the axis 6.
According to what is illustrated in Figure 1, drawing in the pharmaceutical product from the bottle 2 is performed by
setting- the bottle 2 with the membrane 5 facing downwards, orienting the axis 4 of the bottle 2 parallel to a direction 13 set according to an angle different from 0° with respect to a substantially vertical direction 14, setting the syringe 3 with the needle 9 facing upwards, orienting the axis 6 of the syringe 3 according to an angle different from 0° with respect to the direction 14, in the case in point parallel to the direction 13, and displacing the bottle 2 and the syringe 3 with respect to one another in the direction 13 at a relatively high speed to enable the cannula 12 to perforate the membrane '5. In particular, it should be pointed out that the speed of perforation of the membrane 5 is in any case higher than the average speed normally used for displacing the syringe 3 and for displacing the cylinder 7 and the piston 8 with respect to one another.
The inclination of the axes 4 and 6 with respect to the vertical direction 14 and the relatively high speed of perforation of the membrane 5 guarantee a relatively high seal between the cannula 12 and the membrane 5 itself and enable prevention of dripping and leakage of pharmaceutical product from the bottle 2.
The inclination of the axes 4 and 6 with respect to the vertical direction 14 moreover enables orientation of possible air bubbles present within the bottle 2 along a path substantially parallel to the direction 14 and. hence prevention of their suction into the needle 9 and the cylinder 7.
Once the membrane 5 is perforated, the piston 8 is displaced along the cylinder 7 so as to enable the needle 9 to draw in a first amount of pharmaceutical product from the bottle 2. On account of the high seal between the cannula 12 and the membrane 5, the pressure within the bottle 2 decreases so as to be, at the. end of the first suction step, lower than the
pressure within the cylinder 7.
With reference to Figure 2, the bottle 2 and the syringe 3 are then displaced with respect to one another in the direction 13 so .as to enable the element 10 to traverse the membrane 5 and enable the channels 11 to connect the inside of the bottle 2 to the external environment .
Consequently, the pressure within the bottle 2 increases until it reaches a value substantially equal to atmospheric pressure, and the piston 8 is displaced again along the cylinder 7 to enable the needle 9 to draw in a second amount of pharmaceutical product from the bottle 2.
In connection with what is set forth above, it should be pointed out that drawing in the second amount of pharmaceutical product from the bottle 2 must be interrupted at the latest when the level of the pharmaceutical product in the bottle 2 substantially corresponds to an inlet hole (not illustrated) of the cannula 12 so as to prevent the needle 9 from sucking air into the cylinder 7.
Next (see Figure 3), the bottle 2 and the syringe 3 are displaced with respect to one another in the direction 13 for disengaging the element 10 again from the membrane 5, the cannula 12 is kept inside the bottle 2, the axis 4 of the bottle 2 is oriented parallel to the direction 14, and the axis 6 of the syringe 3 is kept parallel to the direction 13.
At this point, the piston 8 is displaced again along the cylinder 7 to enable the needle 9 to draw in a third amount of pharmaceutical product from the bottle 2. The orientation of the axes 4 and 6 enables guaranteeing of a high seal between the membrane 5 and the cannula 12 and hence prevention of dripping and leakage of pharmaceutical product from the bottle 2.
In a way similar to what has been described as regards drawing-in of the second amount of pharmaceutical product, also drawing-in of the third amount of pharmaceutical product from the bottle 2 must be interrupted at the latest., when the level of the pharmaceutical product in the bottle 2 substantially corresponds to the aforesaid inlet hole (not illustrated) of the cannula 12 so as to prevent the needle 9 from sucking air into the cylinder 7.
Finally, with reference to Figure 4, the axis 4 of the bottle 2 is oriented again parallel to the direction 13 , the axis 6 of the syringe 3 is kept parallel to the direction 13 , and the bottle 2 and the syringe 3 are displaced with respect to one another in the direction 13 with a relatively low speed for disengaging the cannula 12 from the membrane 5 and from the bottle 2. The relatively low speed of extraction of the cannula 12 from the membrane 5, which is in any case lower than the speed of perforation of the membrane 5 itself, enables the bottle 2 to be set in communication with the external environment so as to bring about ah increase in the pressure within the bottle 2 up to a value substantially equal to atmospheric pressure.
During the step of extraction of the cannula 12 from the bottle 2, the piston 8 is displaced again along the cylinder 7 to draw the pharmaceutical product contained in the needle 9 into the cylinder 7, thus preventing any possible dripping of pharmaceutical product from the needle 9 itself.
Claims
1.-' A method for drawing in a liquid product from a bottle (2) by means of a syringe (3), the bottle (2) having a first given longitudinal axis (4) and a perforable closing membrane (5) , and the syringe (3) having a second given longitudinal axis
(6) and comprising a containment cylinder (7) , a piston (8) slidably engaged in the containment cylinder (7), and a suction needle (9) , which in turn comprises an engagement element (10) provided with at least one air-relief channel (11) and a cannula (12) fitted on the engagement element (10) itself; the method being characterized in that it comprises the steps of: orienting each of said first and second longitudinal axes (4, 6) according to a first angle and, respectively, a second angle both different from 0° with respect to a substantially vertical reference direction (14) ; perforating the closing membrane (5) via the cannula (12) ; displacing the piston (8) along the containment cylinder (7) to draw in a first amount of product from the bottle (2) ; advancing- the engagement element (10) and hence part of the air-relief channel (11) through the closing membrane (5) ; displacing the piston (8) along the containment cylinder (7) to draw in a second amount of product from the bottle (2) ; extracting the engagement element (10) from the closing membrane ( 5 ) ; and displacing the piston (8) along the containment cylinder .(7) to draw in a third amount of product from the bottle (2) .
2.- The method according to Claim 1 and moreover comprising the step of: maintaining said' first and second angles during suction of said first and second amounts of product.
3. - The method according to Claim 1 or 2 and moreover comprising the step of: - -
orienting the first axis (4) parallel to said reference direction (14) and maintaining said second angle during' the suction of said third amount of product .
4.- The method according to any one of the preceding claims, in which said first and second axes (4, 6) are substantially parallel to one another during perforation of the closing membrane ( 5 ) .
■ 5. - The method according to any one of the preceding claims , in which said first and second axes (4, 6) are substantially parallel to one another during suction of said first and second amounts of product.
6. - The method according to any one of the preceding claims and moreover comprising at the end of the step of drawing-in of the third amount of product, the steps of: orienting the first axis (4) according to said first angle; maintaining said second angle; and extracting the cannula (12) from the closing membrane (5) .
7.- The method according to Claim 6, in which said first and second axes (4, 6) are substantially parallel to one another during extraction of the cannula (12) from the closing membrane (5) .
8.- The method according to Claim 6 or 7, in which the bottle (2) and the syringe (3) are displaced with respect to one another at a first speed during perforation of the closing membrane (5) and at a second speed during extraction of the cannula (12) from the closing membrane (5) itself; the first speed being greater than the second speed.
9.- The method according to any one of the preceding claims, in which the suction of said second and third amounts of product is interrupted at the most when the level of the product in .the bottle (2) substantially corresponds to an inlet hole of the cannula (12) .
10.- The method according to any one of the preceding' claims and 'moreover comprising, during the step of extraction of the cannula (12) from the closing membrane (5), the step of: displacing the piston (8) along the containment cylinder (7)' to draw in a fourth amount of liquid product contained in the suction needle (9) and prevent dripping of the liquid product on the outside of the cannula (12) .
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IT2007/000791 WO2009060486A1 (en) | 2007-11-08 | 2007-11-08 | Method for drawing in a liquid product from a bottle by means of a syringe |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IT2007/000791 WO2009060486A1 (en) | 2007-11-08 | 2007-11-08 | Method for drawing in a liquid product from a bottle by means of a syringe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2009060486A1 true WO2009060486A1 (en) | 2009-05-14 |
Family
ID=39595615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IT2007/000791 Ceased WO2009060486A1 (en) | 2007-11-08 | 2007-11-08 | Method for drawing in a liquid product from a bottle by means of a syringe |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2009060486A1 (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2409343A (en) * | 1943-04-05 | 1946-10-15 | Macalaster Bicknell Company | Fluid inlet-outlet device, particularly for clinical purposes |
| US2541272A (en) * | 1947-04-24 | 1951-02-13 | John T Murphy | Needle for filling or exhausting ampoules |
| US3063451A (en) * | 1959-09-28 | 1962-11-13 | Arthur J Kowalk | Self-venting type needle |
| US6135172A (en) * | 1997-08-20 | 2000-10-24 | Junior Instruments | Device for sampling and/or injecting inside a plugged sample tube |
| WO2002076374A1 (en) * | 2001-03-27 | 2002-10-03 | Eli Lilly And Company | Kit including side firing syringe needle for preparing a drug in an injection pen cartridge |
| WO2004096114A1 (en) * | 2003-04-28 | 2004-11-11 | Glaxosmithkline Biologicals S.A. | Device for introducing a liquid into a pharmaceutical container |
-
2007
- 2007-11-08 WO PCT/IT2007/000791 patent/WO2009060486A1/en not_active Ceased
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2409343A (en) * | 1943-04-05 | 1946-10-15 | Macalaster Bicknell Company | Fluid inlet-outlet device, particularly for clinical purposes |
| US2541272A (en) * | 1947-04-24 | 1951-02-13 | John T Murphy | Needle for filling or exhausting ampoules |
| US3063451A (en) * | 1959-09-28 | 1962-11-13 | Arthur J Kowalk | Self-venting type needle |
| US6135172A (en) * | 1997-08-20 | 2000-10-24 | Junior Instruments | Device for sampling and/or injecting inside a plugged sample tube |
| WO2002076374A1 (en) * | 2001-03-27 | 2002-10-03 | Eli Lilly And Company | Kit including side firing syringe needle for preparing a drug in an injection pen cartridge |
| WO2004096114A1 (en) * | 2003-04-28 | 2004-11-11 | Glaxosmithkline Biologicals S.A. | Device for introducing a liquid into a pharmaceutical container |
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