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WO2009058380A3 - Biomarkers predictive of acute coronary syndromes - Google Patents

Biomarkers predictive of acute coronary syndromes Download PDF

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Publication number
WO2009058380A3
WO2009058380A3 PCT/US2008/012399 US2008012399W WO2009058380A3 WO 2009058380 A3 WO2009058380 A3 WO 2009058380A3 US 2008012399 W US2008012399 W US 2008012399W WO 2009058380 A3 WO2009058380 A3 WO 2009058380A3
Authority
WO
WIPO (PCT)
Prior art keywords
acute coronary
coronary syndromes
biomarkers predictive
reagents
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/012399
Other languages
French (fr)
Other versions
WO2009058380A2 (en
Inventor
Benjamin Horne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IHC Intellectual Asset Management LLC
Original Assignee
IHC Intellectual Asset Management LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IHC Intellectual Asset Management LLC filed Critical IHC Intellectual Asset Management LLC
Publication of WO2009058380A2 publication Critical patent/WO2009058380A2/en
Publication of WO2009058380A3 publication Critical patent/WO2009058380A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to single nucleotide polymorphisms (SNPs) useful in assessing acute coronary syndromes and identifying related cardiovascular risks in humans. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, reagents for detecting the polymorphic nucleic acid molecules and methods of using the nucleic acids as well as methods of using reagents for their detection.
PCT/US2008/012399 2007-10-31 2008-10-31 Biomarkers predictive of acute coronary syndromes Ceased WO2009058380A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98408807P 2007-10-31 2007-10-31
US60/984,088 2007-10-31

Publications (2)

Publication Number Publication Date
WO2009058380A2 WO2009058380A2 (en) 2009-05-07
WO2009058380A3 true WO2009058380A3 (en) 2009-06-25

Family

ID=40591701

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/012399 Ceased WO2009058380A2 (en) 2007-10-31 2008-10-31 Biomarkers predictive of acute coronary syndromes

Country Status (1)

Country Link
WO (1) WO2009058380A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019122340A1 (en) * 2017-12-22 2019-06-27 Université D'aix-Marseille In vitro method for predicting a predisposition to acute coronary syndrome
ES2984299A1 (en) * 2023-03-27 2024-10-29 Fundacion Para La Formacion E Investig Sanitarias De La Region De Murcia [Ffis ACUTE CORONARY SYNDROME BIOMARKER (Machine-translation by Google Translate, not legally binding)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070161031A1 (en) * 2005-12-16 2007-07-12 The Board Of Trustees Of The Leland Stanford Junior University Functional arrays for high throughput characterization of gene expression regulatory elements

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070161031A1 (en) * 2005-12-16 2007-07-12 The Board Of Trustees Of The Leland Stanford Junior University Functional arrays for high throughput characterization of gene expression regulatory elements

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE SNP NCBI; 25 May 2006 (2006-05-25), retrieved from http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs=rs3120784 Database accession no. rs3120784. *
HORNE ET AL.: "Identification and Replication of a Genetic Locus for Myocardial Infarction on Chromosome 1q32.2.", CIRCULATION, vol. 118, 2008, pages 1101 *

Also Published As

Publication number Publication date
WO2009058380A2 (en) 2009-05-07

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