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WO2009054845A1 - Appareil et procédés utilisant des polymères excités par ultrasons pour le soulagement d'une douleur topique - Google Patents

Appareil et procédés utilisant des polymères excités par ultrasons pour le soulagement d'une douleur topique Download PDF

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Publication number
WO2009054845A1
WO2009054845A1 PCT/US2007/082207 US2007082207W WO2009054845A1 WO 2009054845 A1 WO2009054845 A1 WO 2009054845A1 US 2007082207 W US2007082207 W US 2007082207W WO 2009054845 A1 WO2009054845 A1 WO 2009054845A1
Authority
WO
WIPO (PCT)
Prior art keywords
polymer
approximately
ultrasonic waves
further characterized
delivered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/082207
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English (en)
Inventor
Eliaz Babaev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to PCT/US2007/082207 priority Critical patent/WO2009054845A1/fr
Publication of WO2009054845A1 publication Critical patent/WO2009054845A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain

Definitions

  • the present invention relates to pain relief. More particularly, the present invention relates to apparatus and methods using ultrasonically energized polymers for topical pain relief.
  • Treating persistent lingering pain, often but not exclusively associated with arthritis, muscles soreness, headache, etc, with various forms of energy is well known to the art. Most often the energy chosen is a variant of thermal energy, which in particular is heat or cold applied via a portable pad or pack.
  • Applying thermal energy to a portable pack or pad is generally accomplished by means of a chemical reaction or energy transfer by placing the pad or pack in hot environment, such as boiling water or a microwave oven, or a cold environment, such as a fridge or freezer. Transferring thermal energy to a portable pad or pack often results in the pad or pack becoming overheated or overcooled. When placed on the user, an overheated pad or pack can cause the user discomfort or bum the user's skin.
  • an overcooled pad or pack when placed on the user's body can cause the user discomfort or freeze bum the user's skin.
  • Supplying thermal energy to a portable pad or pack can also be accomplished by placing two or more chemicals that are temporarily separated within the pack or pad - these chemicals can be combined to create an endothermic or exothermic chemical reaction.
  • the user activates the pad or pack by removing the barrier separating the reactive chemicals.
  • the use of chemicals in portable packs or pads is hazardous in that the chemicals employed can injure the user's skin if the chemicals were to leak out of the pad or pack.
  • Imparting thermal energy to a location of persistent lingering pain is also accomplished by applying chemicals and creams to the affected area and allowing them to evaporate. Though not effective at generating heat, the evaporation of chemicals applied to the skin can generate a local cooling at the location of the user's body experiencing persistent lingering pain.
  • the use of creams and chemicals is disadvantaged by the fact that such creams and chemicals are often messy to apply and can cause severe irritation if they come in contact with the user's eyes or mucosal membranes, Generating and applying therapeutic energy to a location of the body experiencing persistent lingering pain is also accomplished by electrical stimulation.
  • TENS Transcutaneous Electrical Nerve Stimulation
  • portable versions of TENS, and similar devices have been created and marketed. Requiring batteries or an external power source and often being bulky, TENS devices are not truly portable. Furthermore, the device is worthless if the user of the device is without batteries or an electrical outlet.
  • a method for energizing polymers and using energized polymers for pain relief comprises generating ultrasonic waves having a frequency between 15 kHz and 40 MHz and amplitude of at least 1 micron, and delivering ultrasonic waves to a polymer with an intensity of at least 0.001 watts/cm2 for at least 0, 1 seconds. For example, one could generate ultrasonic waves with a frequency of 30 IcHz and amplitude of 60 'microns and deliver these ultrasonic waves to a crystalline polymer for about 30 seconds, thereby energizing the polymer.
  • a polymer energized in the above described manner may be capable of providing topical pain relief when placed on a patient's skin.
  • crystalline polymers as used herein, means a polymer presenting three-dimensional order on the level of atomic dimensions.
  • the group of crystalline polymers includes semi-crystalline polymers which contain one or more amorphous regions.
  • Ultrasonic waves may be delivered to a polymer through direct contact, a coupling medium, or without contacting the polymer. Direct contact indicates that an ultrasound apparatus delivering ultrasonic waves touches a polymer. Alternatively, or in combination, ultrasonic waves may be delivered to a polymer through a coupling medium such as, but not limited to, gel, liquid, or an additional polymer. It is also possible to deliver ultrasonic waves without touching an ultrasound apparatus to a polymer.
  • An energized polymer may be applied immediately to a patient's skin to provide pain relief, or it may be stored for future use. If the polymer is not to be immediately used, then it may be sealed in a plastic encasement, such as a plastic bag. Darkly colored plastic may retain the energy of the energized polymer better than a clear plastic. At a later time, the plastic encasement may be opened and the energized polymer may be used. A polymer may be exposed to ultrasonic waves more than once, rendering it reusable.
  • a base material such as, but not limited to, metals, polymers, or ceramics.
  • Figure 1 depicts a perspective view of an ultrasound apparatus energizing a polymer.
  • Figure 2 depicts a detailed view of an ultrasound apparatus energizing a polymer.
  • FIG. 1 depicts an ultrasound apparatus capable of energizing a polymer.
  • the ultrasound apparatus comprises an ultrasound power generator 101, a power supply cord 102, an ultrasound transducer 103, an ultrasound horn 104, and an ultrasound tip 105.
  • the power supply cord 102 electrically connects the ultrasound power generator 101 to the ultrasound transducer 103.
  • the ultrasound horn 104 is attached to the distal end of the ultrasound transducer 103.
  • the ultrasound tip 105 is attached to the distal end of the ultrasound horn. Once powered, the ultrasound tip 105 delivers ultrasonic waves to a polymer 106 wliich may be located on a base material ⁇ 07.
  • a method for energizing polymers with the apparatus depicted in Figure 1 comprises generating ultrasonic waves having a frequency between 15 kHz and 40 MHz and amplitude of at least 1 micron, and delivering ultrasonic waves to a polymer with an intensity of at least 0.001 watts/cm2 for at least 0.1 seconds. For example, one could generate ultrasonic waves with a frequency of 30 IcHz and amplitude of 60 microns and deliver these ultrasonic waves to a crystalline polymer for about 30 seconds, thereby energizing the polymer.
  • a polymer energized in the above described manner may be capable of providing topical pain relief when placed on a patient's skin.
  • Figure 1 illustrates delivery of ultrasonic waves without contacting the ultrasound tip 105 to the polymer 106.
  • direct contact may be created by touching the ultrasound tip 105 to the polymer 106.
  • FIG. 2 depicts a detailed view of an ultrasound apparatus energizing a polymer.
  • the ultrasound tip 205 delivers ultrasonic waves to a polymer 206 which may be located on a base material 207. If the base material 207 is reflective in nature, then the ultrasonic waves may be reflected 208 back toward the polymer 206 causing the polymer 206 to be "multipKcatively exposed" to ultrasonic waves.
  • Industrial Applicability :
  • the present invention relates to pain relief. More particularly, the present invention relates to apparatus and methods using ultrasonically energized polymers for topical pain relief.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Percussion Or Vibration Massage (AREA)

Abstract

La présente invention porte sur le soulagement de la douleur. Plus particulièrement, la présente invention porte sur un appareil et des procédés utilisant des polymères excités par ultrasons pour le soulagement d'une douleur topique. Des ondes ultrasonores peuvent être distribuées à un polymère par l'intermédiaire d'un contact direct, d'un milieu de couplage ou sans contact. Un polymère excité peut être appliqué immédiatement à la peau d'un patient pour fournir le soulagement de la douleur, ou ledit polymère excité peut être stocké dans un boîtier en matière plastique pour une utilisation future.
PCT/US2007/082207 2007-10-23 2007-10-23 Appareil et procédés utilisant des polymères excités par ultrasons pour le soulagement d'une douleur topique Ceased WO2009054845A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2007/082207 WO2009054845A1 (fr) 2007-10-23 2007-10-23 Appareil et procédés utilisant des polymères excités par ultrasons pour le soulagement d'une douleur topique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/082207 WO2009054845A1 (fr) 2007-10-23 2007-10-23 Appareil et procédés utilisant des polymères excités par ultrasons pour le soulagement d'une douleur topique

Publications (1)

Publication Number Publication Date
WO2009054845A1 true WO2009054845A1 (fr) 2009-04-30

Family

ID=40579806

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/082207 Ceased WO2009054845A1 (fr) 2007-10-23 2007-10-23 Appareil et procédés utilisant des polymères excités par ultrasons pour le soulagement d'une douleur topique

Country Status (1)

Country Link
WO (1) WO2009054845A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10792495B2 (en) 2016-12-01 2020-10-06 Thimble Bioelectronics, Inc. Neuromodulation device and method for use

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5505932A (en) * 1993-03-26 1996-04-09 Vivorx Pharmaceuticals, Inc. Method for the preparation of fluorocarbon-containing polymeric shells for medical imaging
US6007499A (en) * 1997-10-31 1999-12-28 University Of Washington Method and apparatus for medical procedures using high-intensity focused ultrasound
US6146732A (en) * 1996-12-31 2000-11-14 The Procter & Gamble Company Thermal pack having a plurality of individual heat cells
US6451044B1 (en) * 1996-09-20 2002-09-17 Board Of Regents, The University Of Texas System Method and apparatus for heating inflammed tissue
US20070219481A1 (en) * 2006-03-16 2007-09-20 Eilaz Babaev Apparatus and methods for the treatment of avian influenza with ultrasound

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5505932A (en) * 1993-03-26 1996-04-09 Vivorx Pharmaceuticals, Inc. Method for the preparation of fluorocarbon-containing polymeric shells for medical imaging
US6451044B1 (en) * 1996-09-20 2002-09-17 Board Of Regents, The University Of Texas System Method and apparatus for heating inflammed tissue
US6146732A (en) * 1996-12-31 2000-11-14 The Procter & Gamble Company Thermal pack having a plurality of individual heat cells
US6007499A (en) * 1997-10-31 1999-12-28 University Of Washington Method and apparatus for medical procedures using high-intensity focused ultrasound
US20070219481A1 (en) * 2006-03-16 2007-09-20 Eilaz Babaev Apparatus and methods for the treatment of avian influenza with ultrasound

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10792495B2 (en) 2016-12-01 2020-10-06 Thimble Bioelectronics, Inc. Neuromodulation device and method for use
US11801383B2 (en) 2016-12-01 2023-10-31 Hinge Health, Inc. Neuromodulation device and method for use

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