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WO2009054244A1 - Aggregate of semiconductor nanoparticle phosphor and method for observing single molecule - Google Patents

Aggregate of semiconductor nanoparticle phosphor and method for observing single molecule Download PDF

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Publication number
WO2009054244A1
WO2009054244A1 PCT/JP2008/067916 JP2008067916W WO2009054244A1 WO 2009054244 A1 WO2009054244 A1 WO 2009054244A1 JP 2008067916 W JP2008067916 W JP 2008067916W WO 2009054244 A1 WO2009054244 A1 WO 2009054244A1
Authority
WO
WIPO (PCT)
Prior art keywords
aggregate
semiconductor nanoparticle
nanoparticle phosphor
single molecule
observing single
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/067916
Other languages
French (fr)
Japanese (ja)
Inventor
Kazuyoshi Goan
Makoto Mochizuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Konica Minolta Medical and Graphic Inc
Original Assignee
Konica Minolta Medical and Graphic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Konica Minolta Medical and Graphic Inc filed Critical Konica Minolta Medical and Graphic Inc
Publication of WO2009054244A1 publication Critical patent/WO2009054244A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Luminescent Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

This invention provides an aggregate of a semiconductor nanoparticle phosphor which has been improved in biomolecule recognition performance by utilizing a photoresponsive material as a photoresponsive surface modifying agent, and a method for observing a single molecule using the aggregate of a semiconductor nanoparticle phosphor as a labeling agent. The aggregate of a semiconductor nanoparticle phosphor is characterized in that the surface of the aggregate is modified with the photoresponsive surface modifying agent.
PCT/JP2008/067916 2007-10-26 2008-10-02 Aggregate of semiconductor nanoparticle phosphor and method for observing single molecule Ceased WO2009054244A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-278696 2007-10-26
JP2007278696 2007-10-26

Publications (1)

Publication Number Publication Date
WO2009054244A1 true WO2009054244A1 (en) 2009-04-30

Family

ID=40579350

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/067916 Ceased WO2009054244A1 (en) 2007-10-26 2008-10-02 Aggregate of semiconductor nanoparticle phosphor and method for observing single molecule

Country Status (1)

Country Link
WO (1) WO2009054244A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020246297A1 (en) * 2019-06-04 2020-12-10 株式会社村田製作所 Luminous body, method for manufacturing luminous body, and biological-substance labeling agent

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002544488A (en) * 1999-05-07 2002-12-24 クアンタム ドット コーポレイション Methods for detecting analytes using semiconductor nanocrystals

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002544488A (en) * 1999-05-07 2002-12-24 クアンタム ドット コーポレイション Methods for detecting analytes using semiconductor nanocrystals

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BINDER W.H. ET AL.: "''Surface-modified nanoparticles via thermal and Cu(I)-mediated ''click'' chemistry: Generation of luminescent CdSe nanoparticles with polar ligands guiding supramolecular recognition''", JOURNAL OF MATERIALS CHEMISTRY, vol. 17, no. 20, 28 May 2007 (2007-05-28), pages 2125 - 2132 *
HAHN M.A. ET AL.: "Detection of Single Bacterial Pathogens with Semiconductor Quantum dots", ANALYTICAL CHEMISTRY, vol. 77, no. 15, 1 August 2005 (2005-08-01), pages 4861 - 4869 *
MIKAMI R. ET AL.: "Reversible Photo-Switching of the Magnetization of Iron Oxide Nanoparticles at Room Temperature", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 43, no. 45, 17 November 2004 (2004-11-17), pages 6135 - 6139, Retrieved from the Internet <URL:doi:10.1002/anie.200460964> *
ZHU L. ET AL.: "Light-Controlled Molecular Switches Modulate Nanocrystal Fluorescence", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 127, no. 25, 29 June 2005 (2005-06-29), pages 8968 - 8970 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020246297A1 (en) * 2019-06-04 2020-12-10 株式会社村田製作所 Luminous body, method for manufacturing luminous body, and biological-substance labeling agent
JPWO2020246297A1 (en) * 2019-06-04 2021-12-23 株式会社村田製作所 Luminescent body, manufacturing method of luminescent material, and biomaterial labeling agent
JP7201083B2 (en) 2019-06-04 2023-01-10 株式会社村田製作所 Light-emitting body, method for producing light-emitting body, and biosubstance labeling agent
US12180404B2 (en) 2019-06-04 2024-12-31 Murata Manufacturing Co., Ltd. Light-emitting body, method for producing light-emitting body, and biological material labeling agent

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