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WO2008137549A3 - Methods and compositions for diagnosing osteoarthritis in a feline - Google Patents

Methods and compositions for diagnosing osteoarthritis in a feline Download PDF

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Publication number
WO2008137549A3
WO2008137549A3 PCT/US2008/062225 US2008062225W WO2008137549A3 WO 2008137549 A3 WO2008137549 A3 WO 2008137549A3 US 2008062225 W US2008062225 W US 2008062225W WO 2008137549 A3 WO2008137549 A3 WO 2008137549A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
feline
compositions
osteoarthritis
diagnosing osteoarthritis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/062225
Other languages
French (fr)
Other versions
WO2008137549A2 (en
Inventor
Samer Waleed Khedheyer Al-Murrani
William David Schoenherr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hills Pet Nutrition Inc
Original Assignee
Hills Pet Nutrition Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CN200880022902A priority Critical patent/CN101688247A/en
Application filed by Hills Pet Nutrition Inc filed Critical Hills Pet Nutrition Inc
Priority to US12/600,064 priority patent/US8759258B2/en
Priority to CA2685875A priority patent/CA2685875C/en
Priority to JP2010506638A priority patent/JP5603232B2/en
Priority to EP08747349A priority patent/EP2155904A2/en
Priority to RU2009144277/10A priority patent/RU2504586C2/en
Priority to BRPI0810775-0A2A priority patent/BRPI0810775A2/en
Priority to AU2008247705A priority patent/AU2008247705B2/en
Publication of WO2008137549A2 publication Critical patent/WO2008137549A2/en
Publication of WO2008137549A3 publication Critical patent/WO2008137549A3/en
Anticipated expiration legal-status Critical
Priority to US14/132,187 priority patent/US20140179552A1/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/105Osteoarthritis, e.g. cartilage alteration, hypertrophy of bone
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Methods, compositions and kits for diagnosing osteoarthritis in a feline are disclosed. The methods of the invention comprise detecting differential expression of at least one biomarker in a body sample, preferably a blood sample, where the biomarker is differentially expressed in osteoarthritis.
PCT/US2008/062225 2007-05-01 2008-05-01 Methods and compositions for diagnosing osteoarthritis in a feline Ceased WO2008137549A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
AU2008247705A AU2008247705B2 (en) 2007-05-01 2008-05-01 Methods and compositions for diagnosing osteoarthritis in a feline
US12/600,064 US8759258B2 (en) 2007-05-01 2008-05-01 Methods and compositions for diagnosing osteoarthritis in a feline
CA2685875A CA2685875C (en) 2007-05-01 2008-05-01 Methods and compositions for diagnosing osteoarthritis in a feline
JP2010506638A JP5603232B2 (en) 2007-05-01 2008-05-01 Methods and compositions for diagnosing osteoarthritis in cats
EP08747349A EP2155904A2 (en) 2007-05-01 2008-05-01 Methods and compositions for diagnosing osteoarthritis in a feline
CN200880022902A CN101688247A (en) 2007-05-01 2008-05-01 methods and compositions for diagnosing osteoarthritis in a feline
BRPI0810775-0A2A BRPI0810775A2 (en) 2007-05-01 2008-05-01 METHOD AND KIT FOR DIAGNOSING OSTEOARTHRITIS IN A FELINE, COMPOSITION, AND METHOD FOR IDENTIFYING A COMPONENT TO BE TESTED FOR AN ABILITY TO TREAT OR IMPROVE OSTEOARTHRITIS IN A FELINE.
RU2009144277/10A RU2504586C2 (en) 2007-05-01 2008-05-01 Methods and compositions for diagnostics of osteoarthritis at cat family
US14/132,187 US20140179552A1 (en) 2007-05-01 2013-12-18 Methods and compositions for diagnosing osteoarthritis in a feline

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92716707P 2007-05-01 2007-05-01
US60/927,167 2007-05-01

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/600,064 A-371-Of-International US8759258B2 (en) 2007-05-01 2008-05-01 Methods and compositions for diagnosing osteoarthritis in a feline
US14/132,187 Division US20140179552A1 (en) 2007-05-01 2013-12-18 Methods and compositions for diagnosing osteoarthritis in a feline

Publications (2)

Publication Number Publication Date
WO2008137549A2 WO2008137549A2 (en) 2008-11-13
WO2008137549A3 true WO2008137549A3 (en) 2009-04-16

Family

ID=39944201

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/062225 Ceased WO2008137549A2 (en) 2007-05-01 2008-05-01 Methods and compositions for diagnosing osteoarthritis in a feline

Country Status (9)

Country Link
US (2) US8759258B2 (en)
EP (2) EP2540841B1 (en)
JP (1) JP5603232B2 (en)
CN (1) CN101688247A (en)
AU (1) AU2008247705B2 (en)
BR (1) BRPI0810775A2 (en)
CA (1) CA2685875C (en)
RU (1) RU2504586C2 (en)
WO (1) WO2008137549A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2568823B1 (en) * 2010-05-12 2016-04-27 Hill's Pet Nutrition, Inc. Methods of diagnosis, control and prophylaxis of inflammation and mitigation of inflammatory conditions in felines
BR112013032354A2 (en) * 2011-06-15 2017-01-03 Hills Pet Nutrition Inc COMPOSITIONS AND METHODS FOR DIAGNOSIS AND MONITORING HYPERTHYROIDISM IN A FELINE
AU2012355775B2 (en) 2011-12-19 2015-10-08 Hill's Pet Nutrition, Inc. Compositions and methods for diagnosing and treating hyperthyroidism in companion animals
CN105803085B (en) * 2016-04-27 2019-07-19 范彧 A kind of molecular marked compound and application thereof detecting osteoarthritis
KR102288646B1 (en) * 2020-01-30 2021-08-11 충남대학교산학협력단 Glycan Biomarker for Diagnosing Osteoarthritis of Pets and Method for Diagnosing Osteoarthritis of Pets Using the Same
CN111549144B (en) * 2020-05-07 2023-02-14 深圳有哈科技有限公司 SNP locus for cat strain identification

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001020018A2 (en) * 1999-09-15 2001-03-22 Mitokor Diagnosing and treating arthritic disorders
US20030054426A1 (en) * 2001-08-31 2003-03-20 Welsch Dean J. Peptide biomarker and method of identification
US20050118625A1 (en) * 2003-10-02 2005-06-02 Mounts William M. Nucleic acid arrays for detecting gene expression associated with human osteoarthritis and human proteases
US20050221383A1 (en) * 2003-08-08 2005-10-06 Choong-Chin Liew Osteoarthritis biomarkers and uses thereof
WO2006014013A1 (en) * 2004-08-04 2006-02-09 Riken Bone/joint disease sensitivity gene and use thereof
WO2006138646A2 (en) * 2005-06-17 2006-12-28 The Brigham And Women's Hospital, Inc. Protein profile for osteoarthritis

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4843155A (en) 1987-11-19 1989-06-27 Piotr Chomczynski Product and process for isolating RNA
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5789650A (en) * 1990-08-29 1998-08-04 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5661016A (en) * 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5770429A (en) 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
CA2089661C (en) 1990-08-29 2007-04-03 Nils Lonberg Transgenic non-human animals capable of producing heterologous antibodies
US5633425A (en) * 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5157378A (en) 1991-08-06 1992-10-20 North-South Corporation Integrated firefighter safety monitoring and alarm system
US5932448A (en) * 1991-11-29 1999-08-03 Protein Design Labs., Inc. Bispecific antibody heterodimers
US5545580A (en) * 1995-09-19 1996-08-13 United Microelectronics Corporation Multi-state read-only memory using multiple polysilicon selective depositions
US6506785B2 (en) * 1998-05-22 2003-01-14 Pfizer, Inc. Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives
US20040018188A9 (en) * 1999-01-20 2004-01-29 Incyte Genomics, Inc. Sparc-related proteins
AU2001227526A1 (en) 2000-01-18 2001-07-31 Pharmacia Corporation Osteoarthritis tissue derived nucleic acids, polypeptides, vectors, and cells
US7065236B2 (en) * 2001-09-19 2006-06-20 Tripath Imaging, Inc. Method for quantitative video-microscopy and associated system and computer software program product
AU2002952086A0 (en) 2002-10-16 2002-11-07 The University Of Queensland Treatment of osteoarthritis
JP2004279334A (en) 2003-03-18 2004-10-07 St Marianna Univ School Of Medicine Assay method for osteoarthritis
US20070009899A1 (en) * 2003-10-02 2007-01-11 Mounts William M Nucleic acid arrays for detecting gene expression in animal models of inflammatory diseases
CA2575439A1 (en) 2004-08-18 2006-03-02 The Government Of The United States Of America As Represented By The Sec Retary Of The Department Of Health And Human Services Biomarkers for osteoarthritis
AU2005322887B2 (en) 2004-12-30 2010-03-11 Hill's Pet Nutrition, Inc. Methods for enhancing the quality of life of a senior animal
WO2006086242A2 (en) * 2005-02-07 2006-08-17 Genenews, Inc. Mild osteoarthritis biomarkers and uses thereof
RU2416399C2 (en) 2005-06-29 2011-04-20 Хилл'С Пет Ньютришн, Инк. Methods and compositions for prevention and treatment of inflammatory disease
RU2313096C1 (en) * 2006-05-22 2007-12-20 Государственное образовательное учреждение дополнительного профессионального образования "Новокузнецкий государственный институт усовершенствования врачей Федерального агентства по здравоохранению и социальному развитию" Method for setting differential diagnosis of rheumatoid arthritis cases
MA34939B1 (en) * 2010-05-08 2014-03-01 Bayer Ip Gmbh SUBSTITUTED HETEROCYCLYLBENZYL-PYRAZOLES AND THEIR USE

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001020018A2 (en) * 1999-09-15 2001-03-22 Mitokor Diagnosing and treating arthritic disorders
US20030054426A1 (en) * 2001-08-31 2003-03-20 Welsch Dean J. Peptide biomarker and method of identification
US20050221383A1 (en) * 2003-08-08 2005-10-06 Choong-Chin Liew Osteoarthritis biomarkers and uses thereof
US20050118625A1 (en) * 2003-10-02 2005-06-02 Mounts William M. Nucleic acid arrays for detecting gene expression associated with human osteoarthritis and human proteases
WO2006014013A1 (en) * 2004-08-04 2006-02-09 Riken Bone/joint disease sensitivity gene and use thereof
EP1780276A1 (en) * 2004-08-04 2007-05-02 Riken Bone/joint disease sensitivity gene and use thereof
WO2006138646A2 (en) * 2005-06-17 2006-12-28 The Brigham And Women's Hospital, Inc. Protein profile for osteoarthritis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BLUTEAU G ET AL: "DIFFERENTIAL GENE EXPRESSION ANALYSIS IN A RABBIT MODEL OF OSTEOARTHRITIS INDUCED BY ANTERIOR CRUCIATE LIGAMENT (ACL) SECTION", BIORHEOLOGY, ELSEVIER SCIENCE LTD., OXFORD, GB, vol. 39, no. 1/02, 1 January 2002 (2002-01-01), pages 247 - 258, XP009048751, ISSN: 0006-355X *
DATABASE Geneseq [online] 18 October 2007 (2007-10-18), "Human protease/osteoarthritis gene DNA sequence - SEQ ID 1002.", retrieved from EBI accession no. GSN:AFU75575 Database accession no. AFU75575 *
DATABASE NCBI NUCLEOTIDES [online] NCBI; "Canis familiaris similar to SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON)(Basement-membrane protein 40) (BM-40) (LOC612159), mRNA.", XP002504639, retrieved from NCBI Database accession no. XM_849889 *

Also Published As

Publication number Publication date
CN101688247A (en) 2010-03-31
JP2010526299A (en) 2010-07-29
JP5603232B2 (en) 2014-10-08
US20140179552A1 (en) 2014-06-26
WO2008137549A2 (en) 2008-11-13
AU2008247705A1 (en) 2008-11-13
EP2540841B1 (en) 2015-12-09
CA2685875A1 (en) 2008-11-13
EP2540841A1 (en) 2013-01-02
RU2504586C2 (en) 2014-01-20
BRPI0810775A2 (en) 2014-10-29
CA2685875C (en) 2015-10-06
EP2155904A2 (en) 2010-02-24
US20100323908A1 (en) 2010-12-23
AU2008247705B2 (en) 2012-02-09
US8759258B2 (en) 2014-06-24
RU2009144277A (en) 2011-06-20

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