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WO2008137031A3 - Panels of genetically diverse samples and methods of use thereof - Google Patents

Panels of genetically diverse samples and methods of use thereof Download PDF

Info

Publication number
WO2008137031A3
WO2008137031A3 PCT/US2008/005620 US2008005620W WO2008137031A3 WO 2008137031 A3 WO2008137031 A3 WO 2008137031A3 US 2008005620 W US2008005620 W US 2008005620W WO 2008137031 A3 WO2008137031 A3 WO 2008137031A3
Authority
WO
WIPO (PCT)
Prior art keywords
genetically diverse
panels
methods
samples
diverse samples
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/005620
Other languages
French (fr)
Other versions
WO2008137031A2 (en
Inventor
Michael Wiles
Kenneth Paigen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jackson Laboratory
Original Assignee
Jackson Laboratory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jackson Laboratory filed Critical Jackson Laboratory
Publication of WO2008137031A2 publication Critical patent/WO2008137031A2/en
Publication of WO2008137031A3 publication Critical patent/WO2008137031A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Provided herein are panels of genetically diverse biological samples and methods of use thereof. Exemplary biological samples are those that include cells or tissue. Panels comprise at least 5 genetically diverse samples. The samples may be used for a variety of purposes including examination of the toxicity, effectiveness and/or selectivity of a compound on a genetically diverse population.
PCT/US2008/005620 2007-05-04 2008-05-01 Panels of genetically diverse samples and methods of use thereof Ceased WO2008137031A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92763907P 2007-05-04 2007-05-04
US60/927,639 2007-05-04

Publications (2)

Publication Number Publication Date
WO2008137031A2 WO2008137031A2 (en) 2008-11-13
WO2008137031A3 true WO2008137031A3 (en) 2009-05-07

Family

ID=39944165

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/005620 Ceased WO2008137031A2 (en) 2007-05-04 2008-05-01 Panels of genetically diverse samples and methods of use thereof

Country Status (1)

Country Link
WO (1) WO2008137031A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2564192A1 (en) 2010-04-30 2013-03-06 Universität für Bodenkultur Wien Panels of immortalized mammalian cells and their use
US20220128541A1 (en) * 2019-02-14 2022-04-28 Research Institute At Nationwide Children's Hospital Use of plasma membrane particles, liposomes, and exosomes to assay immune cell potency
CN110910959B (en) * 2019-11-04 2022-08-30 中国水稻研究所 Population genetic evolution map and construction method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002044422A2 (en) * 2000-12-01 2002-06-06 University Of North Carolina - Chapel Hill Method for ultra-high resolution mapping of genes and determination of genetic networks among genes underlying phenotypic traits
WO2008002662A2 (en) * 2006-06-28 2008-01-03 The Univeristy Of Kansas Differentiation of stem cells from umbilical cord matrix into hepatocyte lineage cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002044422A2 (en) * 2000-12-01 2002-06-06 University Of North Carolina - Chapel Hill Method for ultra-high resolution mapping of genes and determination of genetic networks among genes underlying phenotypic traits
WO2008002662A2 (en) * 2006-06-28 2008-01-03 The Univeristy Of Kansas Differentiation of stem cells from umbilical cord matrix into hepatocyte lineage cells

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BROWMAN KAITLIN E ET AL: "Quantitative trait loci affecting ethanol sensitivity in BXD recombinant inbred mice", ALCOHOLISM CLINICAL AND EXPERIMENTAL RESEARCH, vol. 24, no. 1, January 2000 (2000-01-01), pages 17 - 23, XP002507017, ISSN: 0145-6008 *
CANIATO F F ET AL: "Genetic diversity for aluminum tolerance in sorghum", THEORETICAL AND APPLIED GENETICS, vol. 114, no. 5, March 2007 (2007-03-01), pages 863 - 876, XP002507020, ISSN: 0040-5752 *
CANN HOWARD M ET AL: "A human genome diversity cell line panel", SCIENCE (WASHINGTON D C), vol. 296, no. 5566, 12 April 2002 (2002-04-12), pages 261 - 262, XP008099405, ISSN: 0036-8075 *
COBURN J R ET AL: "Design and application of microsatellite marker panels for semiautomated genotyping of rice (Oryza sativa L.).", CROP SCIENCE, vol. 42, no. 6, November 2002 (2002-11-01), pages 2092 - 2099, XP002507015, ISSN: 0011-183X *
SWANSON ET AL: "Performance of the automated Abbott RealTime(TM) HIV-1 assay on a genetically diverse panel of specimens from London: Comparison to VERSANT HIV-1 RNA 3.0, AMPLICOR HIV-1 MONITOR v1.5, and LCx<(>R) HIV RNA Quantitative assays", JOURNAL OF VIROLOGICAL METHODS, ELSEVIER BV, NL, vol. 137, no. 2, 1 November 2006 (2006-11-01), pages 184 - 192, XP005657967, ISSN: 0166-0934 *
TEN ASBROEK ANNELOOR L M A ET AL: "Genetic variation in mRNA coding sequences of highly conserved genes", PHYSIOLOGICAL GENOMICS, vol. 5, June 2001 (2001-06-01), pages 113 - 118, XP002507019, ISSN: 1094-8341 *
TIEDEMANN RODGER E ET AL: "Chemical library screening identifies novel inhibitors of cyclin D2 (CCND2) transactivation that selectively induce apoptosis in multiple myeloma cells.", BLOOD, vol. 108, no. 11, Part 1, November 2006 (2006-11-01), & 48TH ANNUAL MEETING OF THE AMERICAN-SOCIETY-OF-HEMATOLOGY; ORLANDO, FL, USA; DECEMBER 09 -12, 2006, pages 977A, XP008099369, ISSN: 0006-4971 *
YU LI J ET AL: "P450 enzyme expression patterns in the NCI human tumor cell line panel", DRUG METABOLISM AND DISPOSITION, vol. 29, no. 3, March 2001 (2001-03-01), pages 304 - 312, XP002507016, ISSN: 0090-9556 *

Also Published As

Publication number Publication date
WO2008137031A2 (en) 2008-11-13

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