[go: up one dir, main page]

WO2008130591A3 - Using trefoil polypeptides to treat eye lesions associated with ophthalmic procedures - Google Patents

Using trefoil polypeptides to treat eye lesions associated with ophthalmic procedures Download PDF

Info

Publication number
WO2008130591A3
WO2008130591A3 PCT/US2008/004950 US2008004950W WO2008130591A3 WO 2008130591 A3 WO2008130591 A3 WO 2008130591A3 US 2008004950 W US2008004950 W US 2008004950W WO 2008130591 A3 WO2008130591 A3 WO 2008130591A3
Authority
WO
WIPO (PCT)
Prior art keywords
lesions associated
trefoil
ophthalmic procedures
treat eye
eye lesions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/004950
Other languages
French (fr)
Other versions
WO2008130591A2 (en
Inventor
Chee-Wai Woon
Nicholas P Barker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GI Co Inc
Original Assignee
GI Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GI Co Inc filed Critical GI Co Inc
Publication of WO2008130591A2 publication Critical patent/WO2008130591A2/en
Publication of WO2008130591A3 publication Critical patent/WO2008130591A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

A pharmaceutical composition containing a trefoil polypeptide may be used to treat a patient having a lesion of the eye, or pain associated therewith, caused by or associated with an ophthalmic procedure. Trefoil peptides useful for such a composition are disclosed.
PCT/US2008/004950 2007-04-18 2008-04-17 Using trefoil polypeptides to treat eye lesions associated with ophthalmic procedures Ceased WO2008130591A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91249207P 2007-04-18 2007-04-18
US60/912,492 2007-04-18

Publications (2)

Publication Number Publication Date
WO2008130591A2 WO2008130591A2 (en) 2008-10-30
WO2008130591A3 true WO2008130591A3 (en) 2008-12-24

Family

ID=39876124

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/004950 Ceased WO2008130591A2 (en) 2007-04-18 2008-04-17 Using trefoil polypeptides to treat eye lesions associated with ophthalmic procedures

Country Status (2)

Country Link
AR (1) AR066217A1 (en)
WO (1) WO2008130591A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3500255T (en) 2016-08-19 2023-01-10 Orasis Pharmaceuticals Ltd OPHTHALMIC PHARMACEUTICAL COMPOSITIONS AND USES RELATED THERETO
WO2023285878A1 (en) * 2021-07-13 2023-01-19 Aviation-Ophthalmology Methods for detecting, treating, and preventing gpr68-mediated ocular diseases, disorders, and conditions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030186886A1 (en) * 1996-04-12 2003-10-02 Podolsky Daniel K. Treating eye disorders using intestinal trefoil proteins
US20070042951A1 (en) * 2003-10-08 2007-02-22 Allergan, Inc. Pharmaceutical compositions comprising alpha-2-adrenergics and trefoil factor family peptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030186886A1 (en) * 1996-04-12 2003-10-02 Podolsky Daniel K. Treating eye disorders using intestinal trefoil proteins
US20070042951A1 (en) * 2003-10-08 2007-02-22 Allergan, Inc. Pharmaceutical compositions comprising alpha-2-adrenergics and trefoil factor family peptides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GOKE ET AL.: "Trefoil peptides promote restitution of wounded corneal epithelial cells", EXP. CELL RES., vol. 264, no. 2, 1 April 2001 (2001-04-01), pages 337 - 344, Retrieved from the Internet <URL:http://www.sciencedirect.com/science> *

Also Published As

Publication number Publication date
AR066217A1 (en) 2009-08-05
WO2008130591A2 (en) 2008-10-30

Similar Documents

Publication Publication Date Title
WO2008087190A3 (en) Use of peptides in combination with surgical intervention for the treatment of obesity
WO2008087186A3 (en) Peptides for use in the treatment of obesity
WO2007009894A3 (en) Peptides for use in the treatment of obesity
WO2006071778A3 (en) Treatment of parkinson&#39;s disease and related disorders using postpartum derived cells
NZ611108A (en) Methods of treating fgf21-associated disorders
WO2010010551A3 (en) Angiopoietin derived peptides
WO2010114824A8 (en) Substituted azoanthracene derivatives, pharmaceutical compositions, and methods of use thereof
WO2011036445A3 (en) Polypeptides and uses thereof
WO2011020319A8 (en) Fusion protein regulating plasma glucose and lipid, its preparation method and use
NZ596805A (en) Meningococcal fHBP polypeptides
WO2008095177A3 (en) Methods and devices for treating tissue
WO2007120557A3 (en) Method and apparatus of low strengh electric field network-mediated delivery
SG10201912182UA (en) Improved modalities for the treatment of degenerative diseases of the retina
HK1210422A1 (en) Compositions and methods for treating cutaneous scarring
WO2011036442A3 (en) Thrombin c- terminal polypeptides and uses thereof for treating inflammation coagulation disorders
UA99167C2 (en) Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells
WO2008106429A3 (en) Methods and compositions for the treatment of heart failure and other disorders
WO2008087188A3 (en) Peptides for use in the treatment of obesity
WO2012090150A3 (en) New cell-penetrating peptides and uses thereof
WO2009059325A8 (en) Multitype hpv peptide compositions and methods for treatment or prevention of human papillomavirus infection
WO2012083302A3 (en) Compositions and methods for the treatment or prevention of human adenovirus-36 infection
WO2011044443A3 (en) Matricryptic ecm peptides for tissue reconstruction
WO2009111611A3 (en) Compounds, compositions and methods for the treatment of islet amyloid polypeptide (iapp) accumulation in diabetes
WO2011069037A3 (en) Stabilization and storage of biological pharmaceutical compositions
WO2008040190A8 (en) Small peptides for anti-angiogenesis and use thereof

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08754090

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08754090

Country of ref document: EP

Kind code of ref document: A2