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WO2008130380A2 - Procédé et appareil d'obtention d'une carte de pointage de rayonnement - Google Patents

Procédé et appareil d'obtention d'une carte de pointage de rayonnement Download PDF

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Publication number
WO2008130380A2
WO2008130380A2 PCT/US2007/022564 US2007022564W WO2008130380A2 WO 2008130380 A2 WO2008130380 A2 WO 2008130380A2 US 2007022564 W US2007022564 W US 2007022564W WO 2008130380 A2 WO2008130380 A2 WO 2008130380A2
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Prior art keywords
radiation
dose
exposure
patient
program
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WO2008130380A3 (fr
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Bruce Reiner
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5294—Devices using data or image processing specially adapted for radiation diagnosis involving using additional data, e.g. patient information, image labeling, acquisition parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/54—Control of apparatus or devices for radiation diagnosis
    • A61B6/542—Control of apparatus or devices for radiation diagnosis involving control of exposure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/54—Control of apparatus or devices for radiation diagnosis
    • A61B6/545—Control of apparatus or devices for radiation diagnosis involving automatic set-up of acquisition parameters
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q10/00—Administration; Management
    • G06Q10/06—Resources, workflows, human or project management; Enterprise or organisation planning; Enterprise or organisation modelling
    • G06Q10/063—Operations research, analysis or management
    • G06Q10/0637—Strategic management or analysis, e.g. setting a goal or target of an organisation; Planning actions based on goals; Analysis or evaluation of effectiveness of goals
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00—ICT specially adapted for the handling or processing of medical references
    • G16H70/20—ICT specially adapted for the handling or processing of medical references relating to practices or guidelines
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/20—ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS

Definitions

  • the present invention relates to a radiation scorecard which measures, records, analyzes, and reports cumulative radiation exposure to the patient population and provides automated feedback and recommendations to ordering clinicians and consultant radiologists ' and technologists.
  • the data provided from this "radiation scorecard” would in turn be automatically recorded into a centralized data repository (radiation database), which would be independent to the acquisition site, technology employed, and individual end-user.
  • diagnostic medical imaging procedures can expose the patient population to radiation in several different ways including external fixed sources (e.g., radiography or mammography), external moving source (e.g., computed tomography), or internal source (e.g., injected radionuclides).
  • external fixed sources e.g., radiography or mammography
  • external moving source e.g., computed tomography
  • internal source e.g., injected radionuclides
  • Other medical imaging procedures which deliver ionizing radiation to the patient include general radiography, fluoroscopy, interventional fluorography and angiography. Each different procedure had its own unique set of data points that must be recorded and analyzed, in order to calculate the radiation exposure associated with that event.
  • an effective dose In order to compare doses from these different types of imaging procedures, an effective dose must be calculated, which is calculated as the average dose absorbed by body organs and tissues. This effective dose provides a generic equivalent in determining relative radiation risk between different exams but is not specific to the individual patient. In order to accurately track patient-specific radiation dose exposures for a given exam, each individual patient's profile (e.g., body habitus), should be taken into account for accurate quantification of the generic effective dose relative the individual patient - but this is currently not performed.
  • the present invention relates to a prospective, longitudinal technology that would measure, record, analyze, and report cumulative radiation exposure to the patient population and provide automated feedback and recommendations to ordering clinicians and consultant radiologists.
  • the data provided from this "radiation scorecard” would in turn be automatically recorded into a centralized data repository (radiation database), which would be independent to the acquisition site, technology employed, and individual end-user.
  • retrospective analysis can also be performed using a set of pre-defined scorecard data points tied to the individual patient's historical medical imaging database, thereby allowing for comprehensive (both retrospective and prospective) medical radiation exposure quantitative analysis.
  • ionizing radiation e.g., radiation therapy for cancer treatment
  • the corresponding radiation data from these therapeutic procedures would also be incorporated into the Radiation Scorecard, thereby providing cumulative radiation data from all medical procedures (both diagnostic and therapeutic).
  • Scorecard would in turn be used to improve patient safety by a combination of radiation dose reduction, exposure optimization, rigorous equipment quality control (QC), education and training of medical imaging professionals, and integration with computerized physician order entry (CPOE). This data could also be used in the development of new technologies and aimed at reducing environmental, occupational, and medical radiation dose exposures; as well as for medical treatments for radiation- induced disease.
  • QC rigorous equipment quality control
  • CPOE computerized physician order entry
  • the comprehensive anonymized meta-data from large patient populations can be used to track individual risk factors associated with iatrogenic complications (e.g., radiation carcinogenesis).
  • iatrogenic complications e.g., radiation carcinogenesis
  • FIG. 1 is a schematic diagram of the apparatus used in one embodiment consistent with the present invention.
  • FIG. 2 is a flow chart of how to achieve an effective dose according to one embodiment consistent with the present invention.
  • FIG. 3 is a flow chart of how the radiation scorecard is achieved with respect to a clinician's participation, according to one embodiment consistent with the present invention.
  • FIG. 4 is a flow chart of how a technologist performs an imaging examination and utilizes the radiation scorecard and radiation databases, according to one embodiment consistent with the present invention.
  • FIG. 5 is a flow chart of how the radiation scorecard is compiled by analysis of the images taken, of how the analysis of the information is performed, the feedback provided to the stakeholders, and how quality assurance performed, according to one embodiment consistent with the present invention.
  • FIG. 6 is a flow chart of an image analysis procedure to achieve a radiologist's and technologist's scorecard, according to one embodiment consistent with the present invention.
  • a system 100 of the invention is designed to interface with existing information systems such as a Hospital Information System (HIS) 10, a Radiology Information System (RIS) 20, and a Picture Archiving and Communication System (PACS) 30, a radiological or other imaging system 50, among other systems.
  • the system 100 may be configured to conform with the relevant standards, such as the Digital Imaging and Communications in Medicine (DICOM) standard, DICOM Structured Reporting (SR) standard, the Radiological Society of North America's Integrating the Healthcare Enterprise (IHE) initiative, and/or other standards.
  • DICOM Digital Imaging and Communications in Medicine
  • SR DICOM Structured Reporting
  • IHE Integrating the Healthcare Enterprise
  • the electronic consultation system 100 may include a client computer 101, such as a PC, which may or may not be interfaced or integrated with the PACS 30.
  • the invention includes an imaging display device 102 that is capable of providing high resolution of digital images in 2-D or 3-D, for example.
  • the client computer 101 may include a mobile terminal, such as a mobile computing device, or a mobile data organizer (PDA), that is operated by the user accessing the program remotely from the client computer 101.
  • PDA mobile data organizer
  • methods and systems consistent with the invention may be carried out by providing an input mechanism 104 (see FIG. 1), or user selection device, including hot clickable icons etc., or selection buttons, in a menu, dialog box, or a roll-down window of an interface that is provided at the client computer 101.
  • commands may be input through a programmable stylus, keyboard, mouse, speech processing system, laser pointer, touch screen, or other input mechanism 104.
  • the input or selection mechanism 104 may be constituted by a dedicated piece of hardware. Alternatively, the functions of the input or selection mechanism 104 may be executed by code instructions that may be executed on the client processor 106. According to one embodiment, the display unit 102 may display the selection window and a stylus or keyboard for entering a selection, for example.
  • a multi-functional programmable stylus 104 may be provided to enable input of gestures, symbols, and/or icons through the imaging display device 102.
  • other actions may be performed by the multi-functional programmable stylus 104 that are intrinsic to the image display device 102, such as navigation, interpretation, and electronic consultation processes.
  • the actions performed by the multi-functional programmable stylus 104 on the image display device 102 may be superior to actions that are performed using traditional computer keyboard or mouse methods, both within the PACS and Electronic Medical Report (EMR).
  • the client computer 101 typically includes a processor 106 that operates as a client data processing device.
  • the processor 106 may include a central processing unit (CPU) 107 or parallel processor and an input/output (I/O) interface 108, a memory 109 with a program 110 having a data structure 111, wherein all of the components are connected by a bus 112.
  • the client computer 101 may include an input device or means 104, a display 102, and may also include one or more secondary storage devices 113.
  • the bus 112 may be internal to the client computer 101 and may include an adapter for receiving a keyboard or input device 104 or may include external connections.
  • the imaging display device 102 may include a high resolution touch screen computer monitor.
  • the imaging display device 102 may be configured to allow images, such as x-rays, to be readable and for the gestures or symbols to be applied easily and accurately.
  • the imaging display device 102 can be other touch sensitive devices including tablet, pocket PC, and plasma screens.
  • the touch screen would be pressure sensitive and responsive to the input of the stylus 104, which may be used to draw the gestures or symbols of the present invention, directly onto the image displaying device 102.
  • high resolution goggles may be used to provide end users with the ability to review images without the physical constraints of an external computer.
  • a surgeon may wear specialized high resolution goggles to display the cross-sectional radiological image of a brain tumor in 3- D format and may note the gestures on the image, to highlight the pathology in question and to report pertinent characteristics (i.e., anatomic localization, size, etc.), to serve as a guide during surgery.
  • These goggles may be used for image-guided surgery and gesture- based reporting and may serve to provide consultation on pertinent findings during the course of surgery.
  • an internal medicine physician may use these specialized goggles to review images with embedded gestures or symbols.
  • the images could be downloaded using wireless technology and displayed on the goggles, thereby eliminating the need for a computer screen for image display.
  • the graphical user interface associated with the client computer 101 may be a client application that is written to run on existing computer operating systems.
  • the client application may be ported to other personal computer (PC) software, personal digital assistants (PDAs), and cell phones, and any other digital device that has a screen or visual component and appropriate storage capability.
  • the processor 106 at the client computer 101 may be located internal or external thereto, and may execute a program 110 that is configured to include predetermined operations.
  • the processor 106 may access the memory 109 in which may be stored at least one sequence of code instructions comprising the program 110 and the data structure 111 for performing predetermined operations.
  • the memory 109 and program 110 may be located within the client computer 101 or may be located external thereto.
  • the program 110 that runs the electronic consultation method and system may include a separate program code for performing a desired operation or may be a plurality of modules that perform sub- operations of an operation, or may be part of a single module of a larger program 110 providing the operation.
  • the modular construction facilitates adding, deleting, updating and/or amending modules therein and/or features within the modules.
  • the processor 106 may be adapted to access and/or execute a plurality of programs 110 that correspond to a plurality of operations.
  • An operation rendered by the program 110 may include, for example, supporting the user interface, performing data mining functions, performing e-mail applications, etc.
  • the data structure 111 may include a plurality of entries, each entry including at least a first storage area that stores the databases or libraries of gesture symbols, or image files, for example.
  • the storage device 113 may store at least one data file, such as image files, text files, data files, audio, video files, etc., in providing a particular operation.
  • the data storage device may include, for example, a database, such as a distributed database that is connected via a network, for example.
  • the database may be a computer searchable database.
  • the database may be a relational database.
  • the storage device 113 may be connected to the server 120 and/or the client computer 101, either directly or through a communication network, such as a LAN or WAN.
  • a communication network such as a LAN or WAN.
  • an internal storage device 113, or an external storage device 114 is optional, and data may also be received via a network and directly processed.
  • the client computer 101 may be connected to other client computers 101 and/or servers 120, and other medical equipment such as X-ray machines 50 or other imaging equipment.
  • the client computer 101 may also be connected to administration, billing or other systems.
  • the connections may be provided via a communication link 116 as a client communication means, using a communication end port specified by an address or a port.
  • the communication link 116 may include a mobile communication link, a switched circuit communication link, or may involve a network of data processing devices such as a LAN, WAN, the Internet, or combinations thereof.
  • the communication link may be to e-mail systems, fax, telephone, wireless communications systems such as pagers and cell phones, wireless PDA's and other communication systems.
  • the communication link 116 may be an adapter unit capable of executing various communication protocols in order to establish and maintain communication with the server 120, for example.
  • the communication link 116 may be constituted by a specialized piece of hardware or may be realized by a general CPU that executes corresponding program instructions.
  • the communication link 116 may be at least partially included in the processor 106 to execute corresponding program instructions.
  • the server 120 may include a processor 121 having a CPU 122 or parallel processor, which is a server data processing means, and an I/O interface 123.
  • the server 120 may be constituted by a distributed CPU 122, including a plurality of individual processors 121 that are located on one or a plurality of machines.
  • the processor 121 of the server 120 may be a general data processing unit.
  • the processor 121 may include a data processing unit having large resources (i.e., high processing capabilities and a large memory for storing large amounts of data).
  • the server 120 may include a memory 124 with program 125 having a data structure 126, wherein all of the components may be connected by a bus 127.
  • the bus 127 or similar connection line may include external connections, if the server 120 is constituted by a distributed system.
  • the server processor 121 may have access to a storage device 128 for storing preferably large numbers of programs for providing various operations to the users.
  • the data structure 126 may include a plurality of entries, each entry including at least a first storage area which stores image files, for example. According to an alternative embodiment, the data structure 126 may include other stored information as one of ordinary skill in the art would appreciate. [0046] According to one embodiment, the server 120 may be a single unit.
  • the server 120 may be a distributed system of a plurality of servers 120 or data processing units, and may be shared by multiple users in direct or indirect connection to each other.
  • the server 120 may execute at least one server program for a desired operation, which may be needed in serving a request from the client computer 101.
  • the communication link 129 from the server 120 may be adapted to communicate with a plurality of clients .
  • the invention may be implemented in software that may be provided in a client and server environments.
  • the invention may be implemented in software that can be provided in a distributed system over a computerized network across a number of client systems.
  • a particular operation may be performed either at the client or the server, at the edge of a network or at the center, or both. Therefore, at either the client or the server, or both, corresponding programs for a desired operation/service are available.
  • At least one client computer 101 and at least one server 120 are each connected to a network 220 such as a Local Area Network (LAN), Wide Area Network (WAN), and/or the Internet, over communication links 116, 129.
  • a network 220 such as a Local Area Network (LAN), Wide Area Network (WAN), and/or the Internet
  • LAN Local Area Network
  • WAN Wide Area Network
  • imaging equipment 50 are shown as directly connected to the client computer 101, it is known that these systems may be connected to the client over a LAN, WAN, and/or the Internet via communication links.
  • interaction with users may be through secure and non-secure internet connectivity.
  • the steps in the methods consistent with the present invention are carried out at the client computer 101 or at the server 120, or at both.
  • the server 120 may be accessible by the client computer 101 over for example, the Internet using a browser application or the like.
  • the client computer 101 may communicate via a wireless service connection.
  • the server system 120 may communicate with network/security features, via a wireless server, which connects to, for example, voice recognition.
  • voice recognition a system for example, voice recognition.
  • the client computer 101 may be a basic system and the server 120 may include all of the components necessary to support the software platform of the invention. Further, the present client-server system may be arranged such that the client computer 101 may operate independently of the server system 120, but that the server system can be optionally connected. In the former situation, additional modules may be connected to the client computer 101. In another embodiment consistent with the present invention, the client computer 101 and server system 120 may be disposed in one system, rather being separated into two systems.
  • Each new site may maintain "state" with its neighbors so that in the event of a catastrophic failure, other server systems can continue to keep the application running, and allow the system to load-balance the application geographically as required.
  • other computer-readable media such as secondary storage devices, like hard disks, floppy disks, CD-ROM, a carrier wave received from a network such as the Internet, or other forms of ROM or RAM either currently known or later developed.
  • the electronic consultation system 100 and method as used in an exemplary radiology method and system includes a client computer 101 with image displaying device 102, and an input device 104 which is a programmable stylus.
  • the programmable stylus 104 may be used as input mechanism.
  • the programmable stylus 104 may be used to perform other tasks that are intrinsic to the image display, navigation, interpretation, and reporting processes of the invention.
  • the Radiation Scorecard of the present invention is designed to track, record, and analyze all different forms of radiation including (but not limited to) diagnostic and therapeutic medical procedures, environmental, and occupational exposures. Each of these different radiation sources will have its own unique signature, based on the specific characteristics of the radiation (i.e., energy profile), geographic location, and time/duration of exposure.
  • the goal of each imaging acquisition is to collect objective and reproducible radiation data, minimize radiation exposure (and its inherent detrimental effects), maximize the quality of the medical data, and provide data mining to improve healthcare outcomes.
  • the primary strategy is to collect data from the radiation source, which would consist of the medical imaging device (e.g., CT scanner) or therapeutic device (e.g., linear accelerator) 50, for example. Collection strategies are as follows. a. Radiation Dose Calculations
  • CR computed radiography
  • DR direct radiography
  • SED source to image distance
  • SOD source to object distance
  • CR using passive detectors
  • most of these DICOM data fields are not automatically recorded and therefore require manual data inputs (from the technologist acquiring the image), in order to assure the corresponding data is routinely captured and stored for radiation dose calculation.
  • This lack of automated acquisition data tracking also exists with the traditional film-screen radiography.
  • CR systems do however typically provide an exposure index for each individual image, which provides critical information regarding the effective speed class of the image (contained within the DICOM metadata), which can be used to indirectly calculate radiation dose, in the form of entrance skin exposure.
  • This methodology can also be used to retrospectively estimate radiation dose associated with historical radiographic examinations by using reference data including kVp, mAs, and SID specific to each individual exam type.
  • the radiologist may turn on the client computer 101, which may be a stand-alone PC, or a computer connected to a client workstation known in the radiological field as the PACS workstation 30.
  • the client computer 101 may be the PACS 30, and some or all of the present invention, with respect to imaging display device 102, computer memory 109 and program 110 etc., may be contained within the PACS 30 instead of being provided separately.
  • the user may log onto the PACS system 30 once the client computer 101 is operational. Once logged in, the user would bring up the files on the patient in step 301, and would enter and save the specific parameters in step 302, required to accurately estimate the entrance skin dose and effective dose for each patient's particular medical procedure.
  • these requisite parameters include acquisition parameters (e.g., kVp, mAs), location and size of beam, geometrical projection (e.g., AP, lateral, oblique), and patient size/girth.
  • An alternative and system-independent dose calculation can also be derived by using a calibrated dose-area-product (DAP) device installed on the imaging equipment 50 (i.e., x-ray system) within the collimator assembly.
  • entrance skin dose can also be estimated by the user or the program 110 with knowledge of the screen-film speed or exposure index values provided by digital radiography systems (which are contained within the DICOM header), in conjunction with reference values estimated for the specific exam type. Adjustment of the average dose level for a given exam is achieved by the user or the program 110 by taking into account the speed class of the detector and body habitus of the patient.
  • the "matched" reference value (a function of examination, projection, body habitus, detector speed, and patient size/type, e.g., neonate, pediatric, young adult, adult) is the entrance surface dose estimate that is modified by the ratio of the actual measured speed class of the detector (SC D ) determined from the DICOM header information to the speed class of the detector used in Reference Value measurements (SC RV ) to adjust for under or over exposures (SC RV is typically a 400 speed-class value).
  • SC D actual measured speed class of the detector
  • SC RV Reference Value measurements
  • SC RV is typically a 400 speed-class value
  • the area of irradiation (in terms of critical organs) is determined automatically in step 304 by the program 110.
  • the effective dose in mSv
  • the program 110 can automatically calculate the program 110 as the summation of the product of the entrance surface dose times the fractional organ doses times the critical organ dose weighting factors (publicly available in the recently released ICRP-101 (International Commission on Radiation Protection) documentation.)
  • fractional critical organ doses for each different type of radiographic exam performed can be obtained by the program 110 from tabular data that exists within the scientific literature that can be prestored in the computer databases 113, 114, for both adult and pediatric patient populations, based upon Monte Carlo simulations. These fractional values (specific to each individual exam type) can be stored in the computerized database 113, 114 etc. Accordingly, in step 305, the fractional values can be automatically queried by the program 110 at the time of entry of the entrance skin dose into the imaging and information systems databases 113, 114 (e.g., radiology information system (RIS), picture archival and communication system (PACS), and electronic medical record (EMR)), and the effective dose calculated by the program 110 in step 306.
  • RIS radiology information system
  • PES picture archival and communication system
  • EMR electronic medical record
  • the effective dose for each individual exam of each patient is automatically calculated by the program 110 in step 306, the effective dose is downloaded into the patient-specific and universal radiation databases 113, 114 in step 307 and stored by the program 110.
  • An updated patient-specific cumulative radiation dose estimate can then be automatically derived (i.e., cumulative effective dose estimate) by the program 110 in step 308, for user information, as well as the transfer of dose-related data made, in step 309, to the universal radiation database 114 to use for retrieval for research, new technology development, and meta-data analysis.
  • Mammography is somewhat unique in that all significant radiation exposure is confined to the breast.
  • Mean glandular dose is calculated based upon the estimate of the glandular/adipose tissue fraction, compressed breast thickness, and acquisition parameters (kVp, mAs, target/filter, tube output).
  • an estimate of the mean glandular dose is provided with the DICOM metadata, which if validated, can be used in lieu of the calculated entrance surface dose. Since the mean glandular dose is directly associated with radiation carcinogenesis, these values are reported and accumulated for each beast independently.
  • the total effective dose determined by the program 110 is the sum of the individually calculated effective dose estimates for each image acquired. Cumulative dose calculation is critically important for mammography, since guidelines recommend annual screening studies throughout the lifetime of the adult female patient beyond the age of 40.
  • Fluoroscopic procedures present a technical challenge for the calculation of radiation dose exposure due to the dynamic nature of fluoroscopy, the non-stationary x-ray beam, varying techniques resulting from attenuation differences on the changing anatomy being imaged, and the geometrical projections changing with motion over a volume area of the patient. Due to these practical constraints, the only existing way to measure radiation dose levels with fluoroscopy is through the use of a DAP meter and/or point dosimeter, as previously described. While these devices are currently not available in many conventional digital fluoroscopic devices, installation can be easily accomplished, in addition to inclusion of the pertinent data elements into the DICOM image header.
  • GI series e.g., upper GI series, or barium enema
  • An additional crude estimate of radiation dose exposure can be derived by the program 110 from the recorded fluoroscopy time, with a general rule of thumb of 2 R per minute of tabletop exposure per mA at 8OkVp.
  • Estimating effective doses for interventional angiographic exams is calculated by the program in step 306 using the basic requirement that all systems have built-in DAP and point dose measurement devices, and distance measurements including SID and SOD. Similar to fluoroscopy, interventional exams are dynamic in nature and prone to variability. As a result, the recorded DAP and point dose measurements are often not representative of the actual dose received by the patient. For all systems manufactured after June 2006, this data is available in the DICOM XA IOD (information object descriptor) for each acquisition sequence. Using published data values of absorbed organ dose per entrance surface dose and absorbed organ dose per DAP measurements (separate tables for men and women), the effective dose can be calculated by the program 110 using the calculated estimate of the entrance surface dose.
  • ESA entrance surface area
  • IA image area
  • SOD/SID point dosimetry measurements.
  • the Entrance surface dose (mGy) point dose reported value x (30/SOD) 2 , where SOD is expressed in units of cm and 30 (cm) is the distance at which the point dosimeter is calibrated in mGy units.
  • the effective dose is then estimated in the standard way as previously described
  • CTDIw milliGrays
  • mGy milliGrays
  • DLP Dose Length Product
  • ImPACT Scanners
  • CT scanners provide post-scan radiation dose information (CTDI and DLP) in the DICOM metadata (described by the CT IOD).
  • MIRD Medical Internal Radiation Dosimetry
  • This radiation exposure data in nuclear medicine may be captured in the
  • DICOM header and could easily be mandated to accommodate automated dose calculations (see step 628 of Figure 5).
  • This data can in turn be automatically transferred into medical information technologies (e.g., PACS, EMR) by the program 110, for the purposes of creating centralized local, regional, or national radiation databases 114 (see step 309 of Figure 2).
  • medical information technologies e.g., PACS, EMR
  • these calculated data are automatically downloaded by the program 110 into a series of databases 113, 114, which are accessible to the patient and any designated healthcare providers involved in that patient's medical care.
  • retrospective dose exposures can be estimated by the program 110, for example in step 302 (see Figure 2) using historical data points (depending on accuracy) from the patient's medical records contained within a variety of information systems including the EMR, RIS, and PACS. With the recent advent of digital imaging and data storage, retrievability of pertinent data has become far easier and more complete than in the past with analog imaging and paper-based medical records.
  • data may be collected from the radiation source 50 in step 310, which would consist of the medical imaging (e.g., CT scanner) or therapeutic device (e.g., linear accelerator).
  • This data can in turn be automatically transferred into medical information technologies (e.g., PACS, EMR) by the program 110, in step 626 (see Figure 5), for the purposes of creating the centralized local, regional, or national radiation databases 114, for example.
  • medical information technologies e.g., PACS, EMR
  • radiation exposure can be obtained by externally recording all ionizing radiation through an external (or implantable device (e.g., diode)) that would record all radiation exposure to the patient in step 626.
  • the external radiation data monitoring sources 51 can be imbedded within the medical imaging/therapeutic devices 50 or attached to the patient in a number of forms including (but not limited to) jewelry (e.g., bracelet, necklace), implantable computer chips, or physically embedded within clothing, for example.
  • This external radiation monitoring sources 51 can be directly tied to biometrics technology 52 (see for example, U.S. Patent Application No. 11/790,843, filed April 27, 2007, the contents of which are herein incorporated by reference in its entirety) to ensure proper linkage of the radiation data and patient-specific radiation database 113, 114 by the methods described therein.
  • the patient's identification may be established and authenticated using biometrics directly integrated into the imaging device 50 (i.e., CT scanner), as in step 615 (see Figure 4) and then all patient-specific radiation data may be simultaneously transferred by the program 110 to the DICOM header (contained within each individual image), RIS, PACS, and EMR, for example, immediately after exam completion in step 628 (see Figure 5).
  • the data recorded in step 626 by the radiation monitoring sources 51 may include, for example, the date and time of exposure, the duration of exposure, the amount of the dose, the geographic location (using GPS technology), the anatomic area of exposure, the energy profile of the radiation (each radiation source has its own unique profile), as well as the geographic location (longitude/latitude, altitude) of the exposure, during a given interval.
  • the radiation monitoring sources 51 can transfer data to the radiation databases 113, 114 in several ways.
  • scanners/readers 52 can be used, for example, in a hospital, to download information from the radiation monitoring sources 51 and transfer the patient-specific radiation data to the centralized database 113, 114, regionally, nationally, or internationally, at predetermined intervals, using a biometrics tag in the monitoring sources 51, that is specific to the patient.
  • the patient-specific radiation data can be read by wireless devices 53 and stored locally in computers embedded within everyday appliances (e.g., PDA) 54 at the patient's home or office, or downloaded directly, via the internet, into a centralized database 113, 114.
  • the local database in the everyday appliances 54 may be automatically updated each time a new radiation exposure is recorded by the radiation monitoring sources 51. Then the data can be transferred/downloaded by the program 110 from the appliances 54 over the internet, using patient-specific biometrics, into the centralized databases 113, 114 at predetermined intervals (e.g., daily, weekly, monthly).
  • the databases 113, 114 maybe regional, national, and international and would include information from the patient's EMR.
  • the program 110 can cross-reference the downloaded and stored information with each individual patient's calendar, to create a time-stamped radiation profile, that could categorize the radiation source in detail.
  • the combined geographic location e.g., Hospital medical imaging department
  • radiation profile ionizing radiation fitting the profile of a screening mammogram
  • date/time of exposure would be recorded by the radiation monitoring device 51 in step 310, recorded, or read and downloaded by the scanner/reader 52, and saved in a radiation database 113, 114.
  • the program 110 would receive radiation exposure information for a particular anatomic region/critical organ, and would compare it to a maximize radiation exposure for that anatomic region/organ.
  • the program 110 can also analyze the relative quantitative differences in simultaneous exposure when the information is downloaded into the databases 113, 114, and a topographical 3-dimensional anatomic map may be created by the program 110 that illustrates the epicenter of maximal radiation exposure (i.e., anatomic region/organ), as well as the relative decay in radiation exposure as one travels in a 3-dimensional fashion away form this point.
  • This would in effect, create a real-time anatomical, temporal, and quantitative map of radiation exposure that could longitudinally track a patient's radiation exposure over time, with an in-depth analysis of whole body, organ specific, and individual points of exposure. This would be of critical importance when excessively high exposure levels are experienced within a specific, highly sensitive anatomic region.
  • Radiation Scorecard database 113, 114 is principally designed for tracking medically related radiation data, environmental and occupational radiation exposure is also recorded and analyzed, hi the current environment of potential nuclear warfare and terrorism, the Radiation Scorecard also provides a means to define external radiation sources and their associated morbidity and mortality. In a previous section of this document, a number of external (and internal) radiation sensors were described that serve to measure, record, and analyze radiation exposures.
  • external sensors or monitoring devices 51 can serve to continuously monitor environmental radiation levels and identify any unexplained incremental increases in radiation beyond baseline.
  • These sensors 51 can be distributed in a manner similar to ubiquitous computing and linked as individual nodes on a comprehensive network. The location of each sensor 51 would be established using GPS software and any deviations beyond normal baseline can direct an emergency response and early intervention.
  • the epicenter of the radiation exposure can be quickly identified and directionality of the exposure can be immediately established and correlated with environmental factors (e.g., wind speed and direction) to accurately predict extent and direction of contamination.
  • individual sensors can determine sudden changes in radiation exposure to correlate with the external environmental sensors; rapidly identifying those individuals in need of emergent medical care and prophylaxis.
  • an occupational or environmental hazard e.g., radioactive spill, dirty bomb
  • the extent of whole body exposure, as well as critical organ exposure could be calculated using the method and apparatus of the present invention.
  • the program 110 will utilize the information in the radiation scorecard and databases 113, 114 to identify at-risk areas, direct first responders, and facilitate treatment in the event of large-scale radiation contamination.
  • the Radiation Scorecard is designed to track, record, and analyze all different forms of radiation including (but not limited to) diagnostic and therapeutic medical procedures, environmental, and occupational exposures, for example. Each of these different radiation sources will have its own unique signature, based on the specific characteristics of the radiation (i.e., energy profile), geographic location, and time/duration of exposure. c. Radiation Scorecard Implementation
  • the patient presents to the medical imaging department for a new imaging exam, and identification can be established by either using biometrics analysis (integrated directly into the imaging modality) or by using a patient- specific unique identifier in step 612 (see Figure 4). Once the patient is identified within the database 109, 113, 114, the examination can continue.
  • the effective dose is calculated using steps 301-309, and the radiation exposure data inherent to the new imaging study is collected in step 626 and downloaded directly by the program 110 into the centralized database(s) 113, 114 in step 627 for future analysis.
  • the program 110 will then derive standardized information for the
  • the Radiation Scorecard becomes a prospective means to monitor radiation exposure, predict radiation-induced illness, provide prospective feedback on technology utilization (for radiation dose optimization), guide the development of new technologies (e.g., nanotechnology), and treat medical disease (e.g., through new and existing forms of radiation therapy).
  • the databases 113, 114 will include a series of prospective patient and context-specific data as it relates to imaging exam appropriateness criteria, comparative radiation dose exposures (and costs) of different imaging exam options, individualized patient radiation profile, and industrywide standards, which the program 110 will utilize in its analysis.
  • periodic intervals e. g.
  • the program 110 will perform an analysis of the exam ordering, and the clinical, economic, and patient safety concerns based on the clinical indication and patient profile, and provide this information to the clinician in step 609 in the form of a scorecard or "report card grade".
  • This information can in turn, by analyzed by the program 110, for notifying the user in step 610, of issues where remedial education and training may be necessary, with the goals of improving patient safety and diagnostic efficacy of medical imaging.
  • Third-party payers can in turn partially tie physician reimbursement (i.e., Pay for Performance (P4P)) to these objective data contained within the Radiation Scorecard.
  • P4P Pay for Performance
  • Radiologists by training are considered to be de facto experts in the topic of medical imaging radiation and are often deferred to when clinical questions arise as to radiation exposure and patient safety as it relates to ionizing radiation associated with medical imaging. Unfortunately, most radiologists have little if any impact when it comes to the ordering of medical imaging studies. Most imaging departments operate using standardized imaging protocols, which positively impact workflow and operational efficiency, yet has a potentially detrimental effect on the ability to perform dose optimization (which balances the often competing demands for dose reduction and image quality).
  • radiologists By automating radiation dose and medical imaging data collection and analysis as in the present invention, radiologists have the opportunity to become more proactive participants in exam selection, protocol optimization, image processing, image quality analysis, dose reduction, and education and training (clinicians, technologists, and patients). Since radiologists are ultimately responsible for interpretation of medical imaging studies, their input into image quality is essential in the overall Quality Assurance (QA) program.
  • QA Quality Assurance
  • the program 110 may provide an automated procedure which will perform an image analysis of each image taken by the imaging equipment 50, so that a quality analysis can be automatically derived by the program 110 in step 701 (see Figure 6), and electronic feedback of image quality provided for each individual exam to the radiologist in step 702.
  • This image quality can be stored by the program in step in the databases 113, 114, and the program 110 can use this information to create an electronic QA database (see step 703) (as part of or separate from the radiation databases 113, 114).
  • This data can in turn be correlated by the program 110 in step 704, with local, regional, and national reference databases 113, 114 to provide radiologists (individual and groups) with similar report card grades as the clinicians in step 705, which can be updated on a quarterly basis by the program 110 to provide performance feedback. See copending U.S. Patent Application No. 11/412,884.
  • this report card/scorecard information can in turn, by analyzed by the program 110 to notify the user of issues where remedial education and training may be necessary, with the goals of improving radiologist or technologist education and training (similarly to that of the clinician above).
  • This data can also be made available to the public, to facilitate continued educational efforts and informed decision-making.
  • a portion of radiologist (professional component) reimbursement can be tied to these performance metrics (P4P) and continued medical education, thereby creating added incentive to become proactive participants in radiation safety.
  • the program 110 takes into account a number of factors which require consideration including (but not limited to) productivity, exam quality, retake/reject analysis, exposure parameters, image processing employed, and patient adverse outcomes.
  • the program 110 utilizes the radiologist feedback on QA as described above (contained within the QA database 113, 114), to prepare a scorecard or report card for the technologist, which is provided by the program 110 in step 705, in quarterly updates, for example.
  • the technologists have the opportunity to receive regular updates as to QA limitations and the perceived image quality associated with different technical parameters. Technologists who access this data on a regular basis and demonstrate quality improvement, dose reduction, and improved patient safety measures can be recognized and receive financial incentives and promotional opportunities tied to objective performance review.
  • the combination of multiple data points within the Radiation Scorecard provide objective means for analysis at the levels of the individual patient, technologist, technology utilized, department, referring clinician, and peer groups (i.e., institutions) at local, regional, national, and international levels. This provides an administrator with the abilities to not only evaluate performance and adherence to community-wide standards, but also integrate new and existing technologies into workflow to facilitate improved safety and quality measures. The added ability to use this data for education and training purposes (for all stakeholders) (see step 631) creates an added mechanism to incentivize improved measures of performance and provide feedback to outliers.
  • One of the greatest challenges facing administrators is determining "best practice guidelines", determining the optimal balance (between economics, patient safety, and image quality), and integrating disparate technologies.
  • the Radiation Scorecard data provides an effective means to track these parameters (through statistical analysis) in a customized fashion depending upon the unique variables and preferences of each institutional provider.
  • Imaging provider A is developing a new application (e.g., cardiac CT angiography) for its clinical service population.
  • the administrator overseeing implementation must determine what technology to purchase and how it will be integrated into existing technology (e.g., CT scanner, PACS, EMR).
  • the administrator When obtaining quotes from prospective vendors through an RFP (request for proposal), the administrator creates a spreadsheet for comparative analysis that typically compares economic measures and technical specifications (specs) of the technology. Using national data contained within the Radiation and QA Scorecards (that can be fractionated based in institutional demographics to match the host institution), the administrator can identify how the various vendors' technologies differ in quality, workflow, and radiation metrics.
  • the administrator can incorporate additional variables into the comprehensive spreadsheet for analysis that take into account these safety and quality variables and create "weighted" measures according to their own list of priorities.
  • the administrator can identify what specific technology options (e.g., 3-D reconstruction software) and supplemental technologies (e.g., specialized image processing algorithms) that can further improve safety and quality.
  • the Radiation Scorecard provides an objective means to quantify this risk, provide education and feedback as to alternative technologies and new imaging applications, and comparative data as to medical imaging providers' overall performance.
  • all radiation dose exposures (related to medical diagnostic procedures and treatment, occupational, and environmental) are recorded into the master database 113, 114 in step 626. This longitudinal analysis can also provide estimates of previous exposures in step 627 based on the historical data contained within the EMR, PACS, and RIS.
  • the patient profile is then created by the program 110 in step 201 (see
  • Figure 2 after consultation with the patient, which can take into a number of variables including (but not limited to) the following: a) Patient medical problem list (i.e., list of past and current medical problems requiring treatment). b) Family history c) Patient-specific predisposition to new diseases. (These items are derived from genetic (DNA) analysis of the individual patient to identify the relative risk factors which predispose each individual patient to radiation injury and predisposition to new medical/surgical disease processes.) d) Patient susceptibility to radiation-induced injury/illness. (Same as c)). e) Subjective perceptions (of the patient) to radiation, quality, and economics. f) Estimation of non-medical (environmental and occupational) radiation exposures. g) Prospective analysis (as it relates to radiation utilization patterns) of practice patterns of primary and secondary caregivers (i.e., primary care physician, medical/ surgical consultants).
  • a) Patient medical problem list i.e., list of past and current medical problems requiring treatment.
  • This comprehensive data is then reviewed in step 202 with the patient and a multi-disciplinary radiation consultation team (which can consist of medical physicist, primary care physician, radiologist, radiologic technologist, information technology (IT) specialist, and geneticist) to create a customized patient profile.
  • a multi-disciplinary radiation consultation team which can consist of medical physicist, primary care physician, radiologist, radiologic technologist, information technology (IT) specialist, and geneticist
  • the patient can be provided with periodic data tabulations on radiation profiles related to their medical/surgical providers (i.e., their Radiation and QA Scorecard "grades"), different imaging providers, and environmental exposures in step 306 (see Figure 2).
  • the ultimate goal is to create an educated patient population which understands the dangers of radiation and can actively participate in their own healthcare decisions (based on their own preferences and perspectives).
  • the centralized database 113, 114 provides a detailed record of patient imaging exams, thereby reducing the potential for unnecessary and repeat medical imaging exams.
  • Physicists In most community medical imaging facilities, physicists participation in radiation safety is limited to periodic inspection and data collection (on a consulting basis), in order to comply with community standards (e.g., JCAHO, MQSA). This cursory level of involvement satisfies the bare minimum, but does not take advantage of the expertise and specialty training of medical physicists, as it relates to a number of patient-safety radiation concerns such as quality control (QC) and equipment monitoring, dose calibration, and image quality and dose optimization.
  • QC quality control
  • radiation safety measures specific to the technology employed can become integrated into patient safety and provide an objective means to include technology (image display, acquisition, and processing devices) into the overall analysis of patient safety.
  • the medical physicist is an integral part of the multi-disciplinary consultation team. Their job is to create quality control (QC) and quality assurance (QA) programs that take into account quality and safety measures as it relates to the technology being used (both hardware and software). These measures can include the periodic determination of whether equipment used complies with industry and community-wide regulations for safety (i.e., radiation emissions, image quality), integration of phantoms into the modalities for calibration and recording of quality/radiation data, and identification of new technologies (e.g., CAD program specially designed for ultra low-dose CT acquisition parameters) that can further improve the quality/safety profile of the imaging provider and individual patient. [0145] This in effect inserts the medical physicist into the comprehensive evaluation of technology, patient safety, quality measures, prospective data collection and analysis, and physician/patient consultation.
  • QC quality control
  • QA quality assurance
  • the individual Scorecards (patient, radiologist, clinician, physicist, and administrative) are automatically delivered by the program 110 to the respective parties by e-mail, facsimile, etc., in steps 609 and 705, for example.
  • the program 110 provides the scorecards with trending analyses and highlighted areas of outliers (beyond two standard deviations of the mean) in each of the presented metrics (see U.S. Patent Application Nos. 11/699,349, 11/699,350, 11/699,344, 11/699,351, and 11/699,348).
  • Each respective scorecard contains information for the stakeholder that outlines how each measured variable relates to the local, regional, and national counterparts (from data within the respective databases 113, 114). This information is in turn made available to the public and third party payers for P4P programs that tie radiation safety and image quality to reimbursement.
  • the resulting Radiation Scorecard databases 113, 114 can be used for a number of clinical applications pertaining to the individual patient's treatment of existing disease and preventive medicine.
  • the data from a large number of individual patients' databases 113, 114 can be pooled for research purposes to determine new and improved ways to utilize radiation for medical diagnosis and treatment, determine the relationship between specific genetic traits and therapeutic response (relative to radiation), and correlating radiation carcinogenesis risks with genetic profiles.
  • an individual patient with newly diagnosed lung cancer undergoes a series of tests for diagnosis, staging, and treatment planning.
  • the patient has chest radiographs, chest CT, and a nuclear medicine bone scan for staging resulting in a defined radiation exposure for each exam, which is recorded in the Radiation Scorecard database 113, 114 by the program 110 in step 626.
  • the patient also undergoes fluoroscopic biopsy of the lung tumor for diagnosis and the radiation exposure during this procedure is also recorded by the program 110 in step 626.
  • the genetic markers for both the tumor and the individual patient are reviewed and cross-referenced by the program in step 634 with existing databases 113, 114 to determine the aggressiveness of the tumor, response to different types of treatment (e.g., chemotherapy, radiation therapy), and predilection of the patient to incur treatment-related complications (e.g., radiation fibrosis).
  • treatment planning can be optimized using the program 110 in step 202, as well as future screening studies (e.g., serial chest CT exams) scheduled and the data analyzed by the program 110 in step 634, to detect tumor recurrence.
  • future screening studies e.g., serial chest CT exams
  • the cumulative whole body and organ-specific radiation exposure data can be used by the program 110 in step 619 (along with the specific clinical indication) to optimize the test selection, frequency of screening, protocol, and acquisition parameters.
  • the program 110 determines that screening CT exams should be performed on a serial 6 month basis for the next 3 years.
  • Radiation Scorecard of the present invention Another important feature of the Radiation Scorecard of the present invention is the standardization of data elements contained within databases 113, 114, which provides a mechanism for large-scale data mining by the program 110.
  • radiation data such as, exposure parameters utilized for acquisition (kilivoltage (kv) and milliamps (ma)
  • dose optimization techniques employed e.g.
  • the present invention is a Radiation Scorecard including several different components, which individually record data for the user, relative to the patient's individual radiation history (i.e., diagnostic medical imaging performed, such as general radiation, mammography, CT, fluoroscopy, interventional fluorography, and angiography, and nuclear medicine); technical components of the exam performed (i.e., current exam type and dose calculation; specialized dose reduction techniques employed, radiation dose "savings" (comparison of current dose with reference dose), mean dose for alternative imaging exam (based on clinical indication), mean dose of alternative technology for same exam type (e.g., film/screen mammography), mean dose of local, regional, and national reference standards, itemized medical imaging and radiation dose history, cumulative lifetime radiation dose calculation, calculation of lifetime carcinogenesis risk, clinical profile (including current and past medical history); and QA ramifications (such as, exposure parameters utilized for acquisition (kilivoltage (kv) and milliamps (ma)), dose optimization techniques employed (e.g., real-time dose modulation, exposure
  • the individual patient radiation history is intended to provide an educational tool for patients and referring clinicians, for the program 110 to track current and historical radiation exposures, and the relative risk of radiation-induced carcinogenesis. (This is a derived calculation using reference data from the medical literature correlated with the patient's lifetime radiation exposure.)
  • the program 110 In addition for the program 110 to record the current and longitudinal dose measurements incurred to the patient, radiation "savings" will be calculated and reported by the program 110 in the Patient Radiation History Scorecard, by comparing radiation dose measurements associated with the current exam performed with a number of reference dose measurements.
  • Scorecard and will include multiple exam and patient-specific data points used in the calculation of the radiation dose as described previously. Many of these data can be directly acquired from the DICOM (Digital Imaging and Communication in Medicine) header (which is intrinsic to all digital medical images), individual imaging modality, dose area product (DAP) meter, or radiology information system (RIS). g. Quality Assurance and Dose Optimization
  • the QA information is analyzed by the program 110 in step 631 and 632, to correlate radiation dose and image quality and provide valuable feedback to technologists, administrators, physicists, and radiologists as described above, in their combined quest to maximize radiation dose reduction and image quality. As new imaging technologies, applications, and techniques are introduced into clinical practice, this QA database becomes instrumental in providing educational feedback and assist with training.
  • the program 110 creates image quality standards and then adjusts image acquisition parameters for a given medical imaging exam, so that these image quality thresholds are not exceeded (see step 629). By doing so, QA standards are maintained prospectively (while being documented and continuously analyzed by the program 110), and the patient receives the "lowest possible" radiation dose for a given exam.
  • the input data collected by the program 110 and analyzed to define these QA standards takes into account multiple factors including (but not limited to) the clinical indication, anatomic region, imaging modality, patient body habitus, patient medical history, technology utilized, and previous imaging data (in the forms of previous imaging exams, reports, and acquisition parameters).
  • the program 110 can incorporate individual preferences of the interpreting radiologist or clinician (e.g., image processing, display parameters) to ensure that the individual "reader's" preferences are taken into account when determining optimal acquisition parameters.
  • PSNR peak signal to noise ratio
  • JND just-noticeable-difference metric
  • the program 110 optimizes exposure parameters and reduces radiation dose as follows:
  • step 620 an initial ("QA Scout") image is obtained in the customary fashion, but using l/10 th of the conventional dose by the program 110.
  • step 621 this QA Scout image is then reviewed by the program 110 using an objective image quality measuring tool (PSNR or JND), which can quantify the amount of noise contained within the pixels of the Scout image.
  • PSNR objective image quality measuring tool
  • the program 110 then performs a statistical analysis of noise contained within the ultra low dose acquisition image (l/20 th of normal dose), and then automatically queries the comprehensive database 113, 114 in step 622 to determine optimum exposure parameters (i.e., radiation dose) based on a number of factors including (but not limited to): a) Patient preferences (previously described) b) Patient body habitus c) Clinical indication d) Pathology in question e) Pre-defined threshold of image quality.
  • optimum exposure parameters i.e., radiation dose
  • the database 113, 114 is also queried by the program 110 in step 622 to determine how other related technologies (e.g., CAD, specialized image processing algorithms) can be integrated into the process to further reduce image exposure parameters while maintaining the pre-defined image quality threshold.
  • the program 110 can also factor into the equation the performance of the individual radiologist or clinician who will be interpreting the imaging dataset. Based on the QA ad Radiation Scorecard data analysis, each individual "reader" will have a distinct profile as to their own diagnostic accuracy and performance for different degrees of radiation exposure. Some readers may have better performance than others at extremely low dose exposures. This data needs to be factored into the analysis when selecting "optimized" exposure parameters a priori (see steps 623 and 624).
  • Another important application for the QA Scout is the ability of the program 110 to selectively deliver different exposure parameters to different areas of a single exam. For instance, if the exam performed is to re-examine a documented lung nodule, then the specific anatomic area of interest (and pathology) can be identified by the program 110 to insure maximum dose is delivered to that specific region, while lower exposure levels are delivered elsewhere. This in effect can decrease the cumulative radiation exposure without sacrificing the critical diagnostic information and diagnostic accuracy of interpretation.
  • the program 110 of the QA Scout can identify the area of concern and calculate differential exposure parameters in step 624 to ensure detectability of the area of interest, while maintaining lower (yet acceptable) quality parameters in the remaining portion of the imaging exam. If the program 110 was to use the JNDmetric as the visual discrimination model for quantification of image quality (see step 621), they could set the quality threshold of 1 JND (just noticeable difference) in the right upper lobe (where the nodule was previously detected) and set a separate quality threshold of 2 JND for the remaining areas. This data can then be longitudinally tracked by the program 110 (in conjunction with the QA Scorecard) to ensure that diagnostic accuracy is not compromised. By doing so, this becomes an iterative tool to balance the competing demands of optimizing image quality and radiation dose simultaneously.
  • the program 110 then recommends the optimum exposure parameters by determining the lowest exposure parameters which maintain the desired threshold of image quality.
  • a patient has had serial chest radiographic studies with documented pulmonary edema and now has a newly inserted central venous catheter.
  • the current exam was performed to assess catheter placement.
  • the image quality requirements for this exam are not as high as another radiographic exam (performed for the first time), on a patient with cough and suspected lung cancer.
  • image quality requirements may vary according to a number of factors including (but not limited to) the modality, anatomic region being evaluated, clinical indication, past history, and historical imaging exams, which are determined by the program 110.
  • the above technique of the present invention will reduce the radiation exposure by 30-50% over conventional methods and improve overall image quality.
  • the fractional dose of the "QA Scout" image is so low, that it would have a negligible impact on total dose.
  • the ability of the program 110 to dynamically query, retrieve, and analyze data from the Radiation Scorecard (and QA Scorecard) database 113, 114 prior to exam performance improves workflow, image quality, and dose reduction.
  • a query can be automatically generated by the program 110 that reviews a number of parameters including: i) Patient imaging exam history (including prior exposure parameters and corresponding QA ratings) ii) Patient medical history iii) Clinical indication iv) Body habitus (BMI) - available in both the RIS and EMR v) Anatomic region vi) Modality vii) Technology Utilized.
  • the data obtained from this QA/radiation dose optimization process would be stored by the program 110 in the Radiation Scorecard and QA databases 113, 114, and be used in the future by the program 110 for decision support.
  • the program 110 can use this data to perform the following: i) Schedule follow-up exams on the same patient. ii) Formulate a reference database for different patients (who fit the same or similar clinical profiles). iii) Formulate a reference for development of software algorithms (e.g., image processing, CAD) to enhance the detection of pathology using ultra-low dose techniques. iv) Formulate an identification of "disease specific" exposure parameters (e.g., pneumonia versus cancer versus trauma). [0181] While this approach can be utilized for digital radiography and mammography, a modified strategy would be used for CT, which consists of multiple volumetric images (as opposed to a small finite number) within a single exam.
  • a series of ultra- low dose Scout images would be obtained which would create a cross-sectional (i.e., 3 -dimensional) QA Scout image using the following steps.
  • the program 110 determines the amount of noise within pixels of each individual CT QA Scout image.
  • the program 110 determines, in step 621, the optimum exposure parameters to maintain a pre-determined quality threshold and achieve the lowest radiation dose possible.
  • the program 110 will adjust the exposure parameters according to the specific anatomic region being evaluated. For example, in an abdominal/pelvic CT, the optimized exposure parameters would be different when imaging through the liver as opposed to imaging through the bony pelvis, and the program 110 will adjust the parameters accordingly.
  • the combined imaging and Q A/Radiation data is stored and analyzed by the program 110 so that it can be correlated with radiologist/clinician subjective perceptions of image quality to ensure that perceived quality is maintained. Due to differences in visual perception, education, and clinical experience; some radiologists or clinicians may be able to accommodate to a larger degree at increasing levels of noise within an image without compromising diagnostic accuracy.
  • the individual reader performance and subjective perceptions (which are tracked in the Radiologist QA Scorecard) must be correlated with this Radiation Dose Optimization technology (above) to provide the required customization.
  • CAD algorithms will be refined by the program 110 to maximize performance using the ultra-low dose techniques of the present invention.
  • EMR part of the QA/Radiation Scorecard metrics
  • the program 110 identifies a comparable exam and patient profile from an image quality/ radiation dose optimized exam in the database 113, 114 (also, see Decision Support, below) in step 622. If a direct match is not found in the patient's own database 113, 114, then the query by the program 110 tries to identify a "match" from the local, regional, or national databases 113, 114. The technical parameters from this "optimized” exam would be integrated into the patient's imaging file by the program 110 (and stored at the levels of the imaging modality, RIS, and PACS), so that when the technologist prepares to begin the exam these default parameters are displayed by the program 110 in step 707.
  • the various parameters identified by the program 110 would pertain to exposure, collimation, reconstruction and image processing algorithms.
  • the technologist can proceed in one of three ways: i) Use the default parameters. ii) Over-ride the default parameters through manual input. iii) Elect to use the aforementioned "QA Scout" technology to determine optimized parameters based on PSNR/JND analysis of the ultra-low dose scout image.
  • This concept of sequential dose adjustment also applies to serial images within a multi-image exam dataset (e.g., CT) or images that are performed in a temporal fashion for reassessment of previous pathology.
  • a multi-image exam dataset e.g., CT
  • An example of this would be an apical lordotic chest radiograph to evaluate a suspicious nodular density overlying the right apex, visualized on the conventional chest radiographic exam.
  • the critical data contained within the follow-up image is localized to the right apex.
  • QA responsibilities are largely attributed to technologists who acquire the imaging data at the modality, additional QA responsibilities reside within other stakeholders including administrators, radiologists, and clinicians as noted above. A portion of these QA responsibilities deal with ensuring that radiation dose optimization is maintained by utilizing appropriate technology (administrators) (see step 633), appropriate protocols (radiologists) (see step 705), and exam ordering (clinicians) (see step 601). [0196] When the program 110 analyzes corresponding data from the QA and
  • the DQI is a defined as the ratio of radiation dose (as defined by the effective dose) divided by an objective image quality measure (as defined by PSNR or JNDmetric).
  • This index provides a universal mechanism to compare a multitude of factors (e.g., different imaging providers, different types of technology, different patient populations) in radiation dose optimization and for the program 110 to correlate it with clinical outcome measures (e.g., interpretation accuracy). Note that this index can take into account both objective and subjective measures of image quality, with the subjective measures provided by radiologists and clinicians. ⁇ . Decision Support
  • Radiation Scorecard One of the most important benefits of the Radiation Scorecard is its ability to provide guidance to medical imaging multiple stakeholders in the various processes relating to exam optimization, such as: diagnostic medical imaging, institution/facility where exam is performed, technologist performing exam, ordering clinician, interpreting radiologist, room location, equipment specifications, type of exam, technique employed, clinical indication (relevant disease states and diagnoses), equipment quality control (QC) measurements and calibration, mean image quality (QA) score, and calculated dose area product.
  • diagnostic medical imaging institution/facility where exam is performed, technologist performing exam, ordering clinician, interpreting radiologist, room location, equipment specifications, type of exam, technique employed, clinical indication (relevant disease states and diagnoses), equipment quality control (QC) measurements and calibration, mean image quality (QA) score, and calculated dose area product.
  • therapeutic procedure performed the following is collated: therapeutic procedure performed, date, time, and duration of treatment, technology utilized, radiation source, incremental and cumulative radiation dose, physician performing procedure, critical organ doses, 3 -dimensional anatomic reference map of radiation dose exposures, relevant medical/surgical data, side effects/complications of therapy, and list of medications.
  • a genetic profile is collated, using: genetic (DNA) and proteinomic analysis, predisposition to disease states, prediliction to radiation injury, and molecular imaging profile (diagnostic, therapeutic).
  • DNA genetic
  • proteinomic analysis predisposition to disease states
  • prediliction to radiation injury prediliction to radiation injury
  • molecular imaging profile diagnostic, therapeutic
  • CPOE computerized physician order entry
  • the program 110 provides educational feedback to the ordering physician to assist with exam selection.
  • CPOE technology utilizes the clinical information provided to determine the single 'best" medical imaging exam based on a series of appropriateness criteria (see step 602).
  • An exemplary case is where a family practice physician is evaluating a youngster for ankle trauma and suspected fracture. If the physician was to request a CT exam as the initial imaging exam, the program 110 of the CPOE system would instead advise digital radiography as the preliminary screening study based on statistical analysis of large patient populations presenting with similar symptoms and clinical findings.
  • the program 110 of the present invention thus, would take into account the "radiation" ramifications of these medical imaging studies, and will make recommendations for exam selection in step 606. Important factors are taken into account by the program 110 including the patient's pre-existing medical history, prior radiation exposure, and susceptibility to radiation injury, pediatrics, past history of therapeutic radiation, and those patients with genetic profiles placing them at greater risk to radiation-induced injury.
  • the program 110 can cross-reference the clinical history and physical exam findings with these radiation data to provide objective data to the ordering clinician as to the "relative value' of different medical imaging exams for each particular patient.
  • This relative value data can also take into account different exam protocols and allow the referring clinician to select the specific exam of choice after being presented comparative radiation data.
  • a pregnant patient in her second trimester
  • acute onset of shortness of breath and suspected pulmonary embolus blood clot
  • 3 exams commonly ordered which include a pulmonary angiogram (PA), CT angiography of the chest (CTA), and ventilation- perfusion lung scan (VQ).
  • PA pulmonary angiogram
  • CTA CT angiography of the chest
  • VQ ventilation- perfusion lung scan
  • the program 110 can assess that the single "best" exam (from a radiation dose perspective) is ultrasound, followed by CT and then FVP.
  • the standard 3- view abdominal series would add approximately 0.15 rads, which, if the program 110 assesses to be important, could easily be reduced to 0.05 rads by selecting a single supine abdominal radiograph in lieu of the 3-view series.
  • a 6 mm right renal calculus was reported on an outside abdominal radiograph performed two weeks earlier. This was not available in the hospital PACS archive due to the fact it was performed outside of the host institution. When presented with this compilation of data, the clinician elected to go straight to ultrasound with the presumptive diagnosis of right renal calculus.
  • the standard chest radiographic series produces a radiation dose on the order of approximately 0.2 mSv, compared with 5 mSv for a standard chest CT. Due to the fact that the patient had a recently performed "conventional " chest CT, which was reportedly normal; a repeat "conventional" chest CT may not be required. Instead, the program 110 may recommend that an ultra-low dose CT be performed to address the clinical question at hand, and only have an associated radiation dose of 0.1 mSv (less than the standard chest radiograph).
  • This ultra-low dose CT is determined by the program 110 to be efficacious when considering a number of factors including the patient's body habitus (6 feet tall, 140 lbs.), imaging history, presumptive diagnosis (pneumonia), available technology (64-channel CT scanner, specialized image processing algorithms to reduce noise).
  • Scorecard can also function to provide decision support to the technologist.
  • the technologist and radiologist
  • the program 110 presents the option of employing a specialized protocol for the requested chest CT exam, thereby reducing the radiation dose from 5 mSv to 0.1 mSv (see steps 623-625) [0216]
  • the program 110 would present optimized acquisition parameters to the technologist, along with recommendations for specialized image processing algorithms to assist with noise reduction.
  • the present invention simultaneously maximizes image quality and reduces radiation dose within acceptable levels to maintain diagnostic efficacy of the imaging exam.
  • the program 110 can be used to assist in this process.
  • the first is for the program 110 to query the database 113, 114 for exposure parameters used for the same exam type and patients of comparable size (height and weight), and cross reference this with the image quality ratings of those exams (QA
  • Scorecard patent (see step 618).
  • the program 110 would identify those comparable exams (e.g., low dose chest CT), performed on patients of similar body habitus, with the highest image quality ratings. From this list of database candidates, the program 110 would then identify those exams performed for similar clinical indications and on comparable technology, hi the event that specialized software algorithms were utilized for image processing on these high quality exams, the program 110 could offer to provide these to the technologist (downloaded via the Internet) at the time of exam acquisition.
  • comparable exams e.g., low dose chest CT
  • the program 110 would then identify those exams performed for similar clinical indications and on comparable technology, hi the event that specialized software algorithms were utilized for image processing on these high quality exams, the program 110 could offer to provide these to the technologist (downloaded via the Internet) at the time of exam acquisition.
  • An alternative approach to the statistical model would be integration of body habitus measurements into the protocol and acquisition selection process by the program 110.
  • the patient's body mass index (BMI) can be calculated by the program 110 by inputting the height (in inches) and weight (in pounds), along with a subjective measure of muscle mass.
  • the program 110 can then derive optimized acquisition parameters based on a combination of the patient BMI, clinical indication, and exam type from the databases 113, 114.
  • An additional feature of the Radiation Scorecard would be educational/training programs to assist different end-users (technologists, clinicians, administrators) and the patients in understanding the various factors that contribute to radiation and associated healthcare implications.
  • Educational information can also take the form of quantitative predictions of radiation dose associated with a given procedure. These estimated exposure doses would take into account the anatomic region, modality, protocol employed, number of images, and acquisition parameters.
  • program 110 providing this data "up front”, both ordering clinicians and the patients can make educated decisions as to how differences in exam type or technology utilized could impact radiation dose exposure. These real-life quantitative measures will produce more highly educated consumers, reduce radiation exposure, and potentially stimulate new technology development.
  • a number of factors can contribute to increased radiation exposure during a person's lifetime including the increased utilization of non-invasive medical imaging studies for diagnosis and disease prevention, increased patient life expectancy, development of new imaging techniques and applications (e.g., molecular imaging), and the increased use of radiation for therapeutic purposes.
  • the advent of molecular imaging creates the unique possibility of diagnosing disease at the molecular level, which can further add to the cumulative radiation burden over the lifetime of a patient.
  • the program 110 that produces the Radiation Scorecard creates a mechanism to prospectively record, track, and analyze radiation exposure which can arise from medical applications, as well as environmental and occupational exposures. To date, these myriad of radiation sources are not uniformly tracked despite the well documented adverse effects of radiation.
  • the acquired data at the level of the imaging modality is simultaneously archived within multiple information technologies including the RIS, PACS, EMR. All pertinent data is downloaded into a comprehensive Radiation Scorecard database 113, 114 which can be stored at local, regional, national, and international levels. At any time, data can be accessed or added to by the patient or appropriately credentialed healthcare professionals through biometrics authentication.
  • the Radiation Scorecard data is in turn correlated with the individual patient's genetic profile and medical record by the program 110 to determine their underlying risk factors for disease occurrence and morbidity/mortality. As a new medical diagnosis is determined, the genetic profile can be used to predict disease expression. In addition, the Radiation Scorecard database 113, 114 can be queried and analyzed to predict the radiation exposure one would expect for that newly diagnosed disease (based on existing patterns of utilization for screening, diagnosis, and treatment planning) within the designated patient profile.
  • a patient has newly diagnosed lung cancer. Based on the patient's genetic profile and tumor staging (including DNA analysis), an estimate of future radiation exposure (both organ specific and whole body) for this new diagnosis is made based on expected use of medical imaging studies for diagnosis, treatment planning, and surveillance; along with any potential use of radiation for therapy. These disease- specific radiation estimates are continuously updated by the program 110 in accordance with changes in medical/imaging practice, the patient's specific disease state, and new technology developments.
  • new trending analysis is provided by the program 110 to the patient and all designated healthcare providers, along with a calculated carcinogenesis risk based on actuarial analysis.
  • the accuracy of these carcinogenesis measures would improve over time, as more accurate radiation data and outcomes analysis is realized, which is one benefit of the Radiation Scorecard.
  • an emergent notification (with receipt confirmation) would be sent to the healthcare providers by the program 110, along with recommendations for suggested mechanisms to reduce future radiation dose.
  • step 601 the physician places an order for a medical imaging exam using the PACS or RIS or other physician-related apparatus.
  • the Radiation is performed using the PACS or RIS or other physician-related apparatus.
  • Scorecard program 110 will query the Radiation Scorecard Database 113, 114 to determine the exam appropriateness based on the patient's medical history etc.
  • step 603 the program 110 will query the database 113, 114 to determine if comparable imaging data is already present in order to provide a comparison of the type of imaging quality and results should be received.
  • step 604 the program 110 will review the data on the patient, and their scorecard, to calculate the additional radiation burden from the proposed imaging study.
  • This information will be compared by the program in step 605, against a maximum exposure amount that is considered safe for the patient, and the results provided to the clinician in step 606 with recommendations for exam type, protocol, and required interventions using decision support.
  • step 607 the program 110 will provide information on technology options to minimize dose exposure to the patient.
  • step 608 the program 110 will compile a radiation scorecard for the clinician based on the proposed imaging study, taking into account the patient's scorecard
  • the program 110 will provide educational feedback to the clinician (as needed), based on the results of the clinician's scorecard. When educational steps are taken to reduce scorecard issues, the program 110 will take them into account and amend the clinician's scorecard to reflect the positive changes.
  • the exam confirmation is sent to the patient by the program 110 by electronic means (i.e., facsimile, e-mail etc.).
  • the exam confirmation may include optimized exam data, which includes recommendations for dose reduction (based on individual patient and national database analysis from the program 110 query in steps 603 and 605, for example).
  • the program 110 will estimate the radiation dose of the ordered exam and potential alternative studies, and perform a historical review of cumulative dose exposure, and retrieve any associated educational data, and include them in the Radiation Scorecard for clinician, radiologist, technologist, and patient review.
  • the program 110 will retrieve the patient-specific Radiation Scorecard from the patient-specific database 113, 114 in step 613
  • step 614 the program 110 will display the ordered exam specifics and radiation dose data, and the radiologist and clinician will approve the ordered exam and predicted radiation dose.
  • the technologist will prepare the patient for the exam, and in step 615, the program 110 will receive the biometrics from the patient at modality for authentication and access to the Radiation Scorecard database.
  • the program 110 will display the exam profile (exam type, anatomic region, clinical indication, ordering clinician) in step 616, for technologist review and radiologist consultation if needed.
  • step 617 the program 110 will submit an automated query of the
  • Radiation Scorecard database 113, 114 to retrieve patient-specific radiation data, prior exam history, body mass index (BMI), and historic exposure parameters and image quality scores from the national Radiation Scorecard database 113, 114, to obtain comparable data from similar patient and technology profiles in step 618.
  • Variables include: clinical indication, anatomic region, modality, patient body habitus (BMI), documented pathology, past medical history, genetic profile (DNA analysis), technology utilized.
  • the program 110 will determine the optimized exposure parameters and corresponding radiation dose calculations, and identify supporting technologies to enhance dose reduction (e.g., specialized image processing, use of grids/filters), and display the same for the technologist review.
  • supporting technologies to enhance dose reduction e.g., specialized image processing, use of grids/filters
  • step 620 the QA Scout of the program 110 obtains an ultra-low dose scout image obtained (at multiple levels for CT), and in step 621, correlates the scout image with the visual discrimination model (e.g., JNDmetric) to quantify the amount and location of the noise, and calculate the exposure parameters based on noise and predefined image quality threshold.
  • the program 110 queries the Radiation Scorecard database 113,
  • step 623 the program 110 generates options for maximized dose reduction based on selective anatomic regions/pathology of interest, for the radiologist to review and to provide assistance with optimization of the protocol and exposure parameters (ensuring image quality threshold maintained).
  • step 624 the program queries the Radiation Scorecard database 113,
  • This analysis includes a QA Scout quantitative analysis of the image, and will include radiologist/technologist input.
  • step 625 the technologist inputs the exposure parameters with links to the Radiation Scorecard database 113, 114, and conducts the exam.
  • step 626 the exam is acquired and the data collected, and automated calculations of the organ specific dose, effective dose, and comparative dose calculations
  • step 628 the exposure parameters that are recorded are transferred to the DICOM header, along with all pertinent data (patient profile, technology profile, exposure parameters, dose calculations, etc.), which is also transferred to multiple
  • the Patient -specific Radiation Scorecard database 113, 114 is then updated by the program 110 to reflect the current exam. If any predefined thresholds are realized (relative to deficiencies in technology, protocol, acquisition parameters), automated alerts are sent to the respective parties (patient, referring clinician, radiologist administrator) by the program 110 in step 629.
  • the critical threshold is realized (determined by genetic profile of patient, single and cumulative radiation dose exposures, and underlying medical condition of patient)
  • emergent notification is sent by the program 110 in step 630 to a multi- disciplinary Radiation Consultation Team (consisting of medical physicist, IT specialist, technologist, radiologist, administrator, primary care physician).
  • the Radiation Consultation Team serves as a patient advocate to ensure compliance to community- wide standards and make recommendations for required intervention to improve radiation safety. It also serves to ensure physician, radiologist, and technologist performance meets accepted standards.
  • the sources of radiation exposure data could be provided by external (or implantable) sensors which monitor a patient's radiation exposure.
  • Physicist Technology QA/QC metrics, Quality/Dose Indices, Occupational/Environmental Exposures; Administrator: Technologist performance, Patient safety, Medico-legal risk, Departmental compliance; Radiologist: Comparative radiation data (based on local, regional, and national data), Supporting Technologies, Clinician compliance; Clinician: Radiation CME, CPOE compliance, Peer to peer comparative data; IT Specialist: Database integrity, technology integration, data security; and Patient: Cumulative dose exposure, Carcinogenesis risk, Educational Programs. [0259] The program 110 provides the above feedback to each of the stakeholders in step 631 to improve quality assurance.

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Abstract

La présente invention concerne un procédé pour mesurer, enregistrer, analyser et rapporter une exposition cumulative à un rayonnement de la population de patients et transmettre un retour d'informations automatisé et des recommandations automatisées aux cliniciens et radiologues- conseils responsables. Les données transmises par cette « carte de pointage de rayonnement » sont à leur tour automatiquement enregistrées dans un référentiel de données centralisé (base de données de rayonnement), qui est indépendant du site d'acquisition, de la technologie employée et de l'utilisateur final individuel. Une analyse rétrospective peut également être effectuée en utilisant un ensemble de points de données de carte de pointage prédéfinis liés à la base de données d'imagerie médicale historique du patient individuel, permettant ainsi une analyse quantitative complète de l'exposition à un rayonnement médical (à la fois rétrospective et prospective). La sécurité du patient peut être améliorée par une combinaison d'une réduction de la dose de rayonnement, d'une optimisation de l'exposition, d'un contrôle qualité (QC) rigoureux du matériel, de la formation et de l'entraînement des professionnels de l'imagerie médicale et de l'intégration d'une saisie d'ordonnances médicales informatisées (CPOE).
PCT/US2007/022564 2006-10-25 2007-10-25 Procédé et appareil d'obtention d'une carte de pointage de rayonnement Ceased WO2008130380A2 (fr)

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