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WO2008127640A3 - Substituted benzimidazoles - Google Patents

Substituted benzimidazoles Download PDF

Info

Publication number
WO2008127640A3
WO2008127640A3 PCT/US2008/004689 US2008004689W WO2008127640A3 WO 2008127640 A3 WO2008127640 A3 WO 2008127640A3 US 2008004689 W US2008004689 W US 2008004689W WO 2008127640 A3 WO2008127640 A3 WO 2008127640A3
Authority
WO
WIPO (PCT)
Prior art keywords
substituted benzimidazoles
substituted
processes
formula
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/004689
Other languages
French (fr)
Other versions
WO2008127640A2 (en
Inventor
Thomas G Gant
Sepehr Sarshar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Auspex Pharmaceuticals Inc
Original Assignee
Auspex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Auspex Pharmaceuticals Inc filed Critical Auspex Pharmaceuticals Inc
Publication of WO2008127640A2 publication Critical patent/WO2008127640A2/en
Publication of WO2008127640A3 publication Critical patent/WO2008127640A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Disclosed herein are substituted benzimidazole-based proton pump modulators of Formula I, processes of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
PCT/US2008/004689 2007-04-11 2008-04-11 Substituted benzimidazoles Ceased WO2008127640A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91126407P 2007-04-11 2007-04-11
US60/911,264 2007-04-11

Publications (2)

Publication Number Publication Date
WO2008127640A2 WO2008127640A2 (en) 2008-10-23
WO2008127640A3 true WO2008127640A3 (en) 2008-12-04

Family

ID=39768958

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/004689 Ceased WO2008127640A2 (en) 2007-04-11 2008-04-11 Substituted benzimidazoles

Country Status (1)

Country Link
WO (1) WO2008127640A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006299424A1 (en) 2005-10-06 2007-04-12 Auspex Pharmaceuticals, Inc. Deuterated inhibitors of gastric H+, K+-ATPase with enhanced therapeutic properties
CN103364546B (en) * 2012-04-05 2016-03-30 北京勤邦生物技术有限公司 A kind of kit and method detecting Furaxone metabolite

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007012650A1 (en) * 2005-07-26 2007-02-01 Nycomed Gmbh Isotopically substituted proton pump inhibitors
WO2007041630A1 (en) * 2005-10-06 2007-04-12 Auspex Pharmaceuticals, Inc. Deuterated inhibitors of gastric h+, k+-atpase with enhanced therapeutic properties

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007012650A1 (en) * 2005-07-26 2007-02-01 Nycomed Gmbh Isotopically substituted proton pump inhibitors
WO2007041630A1 (en) * 2005-10-06 2007-04-12 Auspex Pharmaceuticals, Inc. Deuterated inhibitors of gastric h+, k+-atpase with enhanced therapeutic properties

Also Published As

Publication number Publication date
WO2008127640A2 (en) 2008-10-23

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