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WO2008126401A1 - Appareil pour le repliement d'une protéine - Google Patents

Appareil pour le repliement d'une protéine Download PDF

Info

Publication number
WO2008126401A1
WO2008126401A1 PCT/JP2008/000878 JP2008000878W WO2008126401A1 WO 2008126401 A1 WO2008126401 A1 WO 2008126401A1 JP 2008000878 W JP2008000878 W JP 2008000878W WO 2008126401 A1 WO2008126401 A1 WO 2008126401A1
Authority
WO
WIPO (PCT)
Prior art keywords
protein
refolding
column
refolding protein
zeolite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/000878
Other languages
English (en)
Japanese (ja)
Inventor
Masayuki Kawakami
Tatsuo Tsunoda
Hideaki Togashi
Takayuki Nara
Shun-Ichi Matsuura
Chisato Sekikawa
Akiko Kawai
Akiyoshi Kawata
Fujio Mizukami
Kengo Sakaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute of Advanced Industrial Science and Technology AIST
Fujifilm Corp
Original Assignee
National Institute of Advanced Industrial Science and Technology AIST
Fujifilm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Institute of Advanced Industrial Science and Technology AIST, Fujifilm Corp filed Critical National Institute of Advanced Industrial Science and Technology AIST
Priority to JP2009508912A priority Critical patent/JP5083840B2/ja
Publication of WO2008126401A1 publication Critical patent/WO2008126401A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

On vise à proposer un appareil pour le repliement d'une protéine efficace pour le repliement (à savoir la potentialisation fonctionnelle) d'une protéine produite par Escherichia coli, etc. qui est inactive en raison du manque de structure d'ordre supérieur ou d'une protéine inactivée dont la structure stérique a été modifiée pour une certaine raison. A savoir, l'invention porte sur un appareil pour le repliement d'une protéine doté d'au moins une colonne pour le repliement d'une protéine garnie avec un garnissage de colonne pour le repliement d'une protéine contenant une zéolite granulée de structure BEA (zéolite bêta).
PCT/JP2008/000878 2007-04-05 2008-04-04 Appareil pour le repliement d'une protéine Ceased WO2008126401A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009508912A JP5083840B2 (ja) 2007-04-05 2008-04-04 タンパク質リフォールディング装置

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007099285 2007-04-05
JP2007-099285 2007-04-05

Publications (1)

Publication Number Publication Date
WO2008126401A1 true WO2008126401A1 (fr) 2008-10-23

Family

ID=39863561

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/000878 Ceased WO2008126401A1 (fr) 2007-04-05 2008-04-04 Appareil pour le repliement d'une protéine

Country Status (2)

Country Link
JP (1) JP5083840B2 (fr)
WO (1) WO2008126401A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010050485A1 (fr) * 2008-10-28 2010-05-06 学校法人関西学院 Agent de repliement et procédé de repliement de protéine
CN113453777A (zh) * 2019-02-28 2021-09-28 思拓凡瑞典有限公司 在优化色谱系统的操作方面以及涉及此的改进
WO2024143439A1 (fr) * 2022-12-28 2024-07-04 富士フイルム株式会社 Procédé de fabrication de support régénéré, solution de lavage, kit, et procédé de fabrication de vésicules extracellulaires

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004330113A (ja) * 2003-05-08 2004-11-25 Pentax Corp 吸着剤の製造方法および吸着剤
WO2005005459A1 (fr) * 2003-07-09 2005-01-20 National Institute Of Advanced Industrial Science And Technology Materiaux de repliement de proteine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004330113A (ja) * 2003-05-08 2004-11-25 Pentax Corp 吸着剤の製造方法および吸着剤
WO2005005459A1 (fr) * 2003-07-09 2005-01-20 National Institute Of Advanced Industrial Science And Technology Materiaux de repliement de proteine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"Amersham Pharmacia Biotech", LIFE SCIENCE NEWS (JAPAN ED.), vol. 2, 2001, pages 13 - 14 *
CHIKU H. ETA L.: "A novel protein refolding method using a zeolite", ANAL. BIOCHEM., vol. 348, no. 2, 2006, pages 307 - 314, XP005217382 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010050485A1 (fr) * 2008-10-28 2010-05-06 学校法人関西学院 Agent de repliement et procédé de repliement de protéine
CN113453777A (zh) * 2019-02-28 2021-09-28 思拓凡瑞典有限公司 在优化色谱系统的操作方面以及涉及此的改进
CN113453777B (zh) * 2019-02-28 2024-03-08 思拓凡瑞典有限公司 在优化色谱系统的操作方面以及涉及此的改进
WO2024143439A1 (fr) * 2022-12-28 2024-07-04 富士フイルム株式会社 Procédé de fabrication de support régénéré, solution de lavage, kit, et procédé de fabrication de vésicules extracellulaires

Also Published As

Publication number Publication date
JPWO2008126401A1 (ja) 2010-07-22
JP5083840B2 (ja) 2012-11-28

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