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WO2008111446A1 - ２，５－ジヒドロフランの連続的な製造方法 - Google Patents

２，５－ジヒドロフランの連続的な製造方法 Download PDF

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Publication number
WO2008111446A1
WO2008111446A1 PCT/JP2008/053917 JP2008053917W WO2008111446A1 WO 2008111446 A1 WO2008111446 A1 WO 2008111446A1 JP 2008053917 W JP2008053917 W JP 2008053917W WO 2008111446 A1 WO2008111446 A1 WO 2008111446A1
Authority
WO
WIPO (PCT)
Prior art keywords
dihydrofuran
continuously producing
alumina
acetal
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/053917
Other languages
English (en)
French (fr)
Inventor
Junichi Fuji
Shigeru Okano
Katsushi Nagareda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuraray Co Ltd
Original Assignee
Kuraray Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co Ltd filed Critical Kuraray Co Ltd
Priority to JP2009503986A priority Critical patent/JP5357750B2/ja
Priority to EP08721337.7A priority patent/EP2133344B1/en
Priority to CN2008800066637A priority patent/CN101622237B/zh
Priority to US12/529,548 priority patent/US8039645B2/en
Priority to ES08721337.7T priority patent/ES2494850T3/es
Publication of WO2008111446A1 publication Critical patent/WO2008111446A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/28—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)

Abstract

アルミナの存在下にシス－２－ブテン－１，４－ジオールを液相にて脱水環化反応させる際、反応系内に存在するカルボニル化合物およびアセタール化合物の反応混合液中における濃度（但し、アセタール化合物の濃度は、アセタール基換算での濃度とする。）の合計を０．１～２ｍｏｌ／Ｌの範囲内に制御することにより、医農薬原料、ポリマー原料などの原料・中間体などとして有用な２，５－ジヒドロフランを連続的に製造する方法であり、γ－アルミナの失活を抑制でき、長期的な工業的生産に有利な製造方法である。
PCT/JP2008/053917 2007-03-06 2008-03-05 ２，５－ジヒドロフランの連続的な製造方法 Ceased WO2008111446A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2009503986A JP5357750B2 (ja) 2007-03-06 2008-03-05 ２，５−ジヒドロフランの連続的な製造方法
EP08721337.7A EP2133344B1 (en) 2007-03-06 2008-03-05 Method for continuously producing 2,5-dihydrofuran
CN2008800066637A CN101622237B (zh) 2007-03-06 2008-03-05 2,5-二氢呋喃的连续制造方法
US12/529,548 US8039645B2 (en) 2007-03-06 2008-03-05 Method for continuously producing 2,5-dihydrofuran
ES08721337.7T ES2494850T3 (es) 2007-03-06 2008-03-05 Método de producción continua de 2,5-dihidrofurano

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-055140 2007-03-06
JP2007055140 2007-03-06

Publications (1)

Publication Number Publication Date
WO2008111446A1 true WO2008111446A1 (ja) 2008-09-18

Family

ID=39759389

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/053917 Ceased WO2008111446A1 (ja) 2007-03-06 2008-03-05 ２，５－ジヒドロフランの連続的な製造方法

Country Status (6)

Country Link
US (1) US8039645B2 (ja)
EP (1) EP2133344B1 (ja)
JP (1) JP5357750B2 (ja)
CN (1) CN101622237B (ja)
ES (1) ES2494850T3 (ja)
WO (1) WO2008111446A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102633754B (zh) * 2012-03-28 2014-02-05 南开大学 用改性纳米氧化铝催化剂制备高纯度2,5-二氢呋喃的方法
CN106397372B (zh) * 2015-07-27 2019-01-08 浙江捷达科技有限公司 一种3-甲胺四氢呋喃的制备方法
CN106496164B (zh) * 2016-09-30 2019-01-29 浙江捷达科技有限公司 一种二氢呋喃连续化合成及异构体分离的方法
CN106432143B (zh) * 2016-09-30 2019-02-19 浙江捷达科技有限公司 一种二氢呋喃连续化生产及分离的装置
CN107935970B (zh) * 2017-12-27 2020-04-28 浙江先锋科技股份有限公司 一种高纯度低含水量3-甲胺四氢呋喃的制备方法
CN117138713A (zh) * 2023-10-30 2023-12-01 天津凯莱英医药科技发展有限公司 呋喃类化合物的连续化合成系统及方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3165536A (en) * 1965-01-12 Certificate of correction
DE1211219B (de) 1961-06-29 1966-02-24 Basf Ag Verfahren zur Herstellung von 2, 5-Dihydrofuran
US4196130A (en) * 1977-04-11 1980-04-01 Basf Aktiengesellschaft Manufacture of cyclic ethers
JPS5673080A (en) 1979-07-25 1981-06-17 Basf Ag Manufacture of cyclic ether
JPH09110850A (ja) 1995-10-24 1997-04-28 Mitsui Toatsu Chem Inc ２，５−ジヒドロフランの製造法
JPH10502363A (ja) 1994-07-06 1998-03-03 ビーエーエスエフ アクチェンゲゼルシャフト ブチンジオールからブテンジオールへの選択的水素添加のための方法並びに触媒
JPH11349581A (ja) * 1998-06-02 1999-12-21 Mitsubishi Chemical Corp ジヒドロフラン類の製造法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3165536A (en) * 1965-01-12 Certificate of correction
DE1211219B (de) 1961-06-29 1966-02-24 Basf Ag Verfahren zur Herstellung von 2, 5-Dihydrofuran
US4196130A (en) * 1977-04-11 1980-04-01 Basf Aktiengesellschaft Manufacture of cyclic ethers
JPS5673080A (en) 1979-07-25 1981-06-17 Basf Ag Manufacture of cyclic ether
JPH10502363A (ja) 1994-07-06 1998-03-03 ビーエーエスエフ アクチェンゲゼルシャフト ブチンジオールからブテンジオールへの選択的水素添加のための方法並びに触媒
JPH09110850A (ja) 1995-10-24 1997-04-28 Mitsui Toatsu Chem Inc ２，５−ジヒドロフランの製造法
JPH11349581A (ja) * 1998-06-02 1999-12-21 Mitsubishi Chemical Corp ジヒドロフラン類の製造法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"Organic Structure", vol. 13, article "Shin-Jikken Kagaku Koza", pages: 57 - 58
INDUSTRIAL ENG. CHEM. PRODUCT RES.& DEV., vol. 12, no. 3, 1973, pages 184 - 189
See also references of EP2133344A4 *

Also Published As

Publication number Publication date
JP5357750B2 (ja) 2013-12-04
CN101622237B (zh) 2012-07-18
EP2133344B1 (en) 2014-06-18
US20100087665A1 (en) 2010-04-08
ES2494850T3 (es) 2014-09-16
CN101622237A (zh) 2010-01-06
JPWO2008111446A1 (ja) 2010-06-24
US8039645B2 (en) 2011-10-18
EP2133344A4 (en) 2010-07-07
EP2133344A1 (en) 2009-12-16

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