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WO2008156638A3 - Method of treating disorders that would benefit from increased levels of bilirubin in a subject - Google Patents

Method of treating disorders that would benefit from increased levels of bilirubin in a subject Download PDF

Info

Publication number
WO2008156638A3
WO2008156638A3 PCT/US2008/007340 US2008007340W WO2008156638A3 WO 2008156638 A3 WO2008156638 A3 WO 2008156638A3 US 2008007340 W US2008007340 W US 2008007340W WO 2008156638 A3 WO2008156638 A3 WO 2008156638A3
Authority
WO
WIPO (PCT)
Prior art keywords
bilirubin
benefit
subject
increased levels
treating disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/007340
Other languages
French (fr)
Other versions
WO2008156638A2 (en
Inventor
Fritz H Bach
Martin C Carey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Beth Israel Deaconess Medical Center Inc
Original Assignee
Brigham and Womens Hospital Inc
Beth Israel Deaconess Medical Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham and Womens Hospital Inc, Beth Israel Deaconess Medical Center Inc filed Critical Brigham and Womens Hospital Inc
Publication of WO2008156638A2 publication Critical patent/WO2008156638A2/en
Publication of WO2008156638A3 publication Critical patent/WO2008156638A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Methods of treating diseases or disorders that would benefit from increased levels of bilirubin are described.
PCT/US2008/007340 2007-06-15 2008-06-12 Method of treating disorders that would benefit from increased levels of bilirubin in a subject Ceased WO2008156638A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93468607P 2007-06-15 2007-06-15
US60/934,686 2007-06-15

Publications (2)

Publication Number Publication Date
WO2008156638A2 WO2008156638A2 (en) 2008-12-24
WO2008156638A3 true WO2008156638A3 (en) 2009-05-28

Family

ID=39952270

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/007340 Ceased WO2008156638A2 (en) 2007-06-15 2008-06-12 Method of treating disorders that would benefit from increased levels of bilirubin in a subject

Country Status (1)

Country Link
WO (1) WO2008156638A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4968495A (en) * 1987-08-28 1990-11-06 Amano Pharmaceutical Co., Ltd. Chemically modified bilirubin oxidase
WO2002004501A1 (en) * 2000-06-14 2002-01-17 Biowindow Gene Development Inc. Shanghai A novel polypeptide - human beta-glucuronidase 11.88 and a polynucleotide encoding the same
EP1228767A1 (en) * 2001-01-31 2002-08-07 S.A.R.M. S.r.l. Use of beta-Glucuronidase for the treatment of immune or allergic diseases

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4968495A (en) * 1987-08-28 1990-11-06 Amano Pharmaceutical Co., Ltd. Chemically modified bilirubin oxidase
WO2002004501A1 (en) * 2000-06-14 2002-01-17 Biowindow Gene Development Inc. Shanghai A novel polypeptide - human beta-glucuronidase 11.88 and a polynucleotide encoding the same
EP1228767A1 (en) * 2001-01-31 2002-08-07 S.A.R.M. S.r.l. Use of beta-Glucuronidase for the treatment of immune or allergic diseases

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200214, Derwent World Patents Index; AN 2002-106607, XP002520427 *

Also Published As

Publication number Publication date
WO2008156638A2 (en) 2008-12-24

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