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WO2008146883A1 - 睡眠改善剤 - Google Patents

睡眠改善剤 Download PDF

Info

Publication number
WO2008146883A1
WO2008146883A1 PCT/JP2008/059925 JP2008059925W WO2008146883A1 WO 2008146883 A1 WO2008146883 A1 WO 2008146883A1 JP 2008059925 W JP2008059925 W JP 2008059925W WO 2008146883 A1 WO2008146883 A1 WO 2008146883A1
Authority
WO
WIPO (PCT)
Prior art keywords
sleep
improving agent
improving
sedative agent
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/059925
Other languages
English (en)
French (fr)
Inventor
Yoshihiro Urade
Zhi-Li Huang
Masashi Wada
Nahoko Uchiyama
Tenji Konishi
Norio Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osaka Bioscience Institute
Doshisha Co Ltd
KUREI OKINAWA CO Ltd
Original Assignee
Osaka Bioscience Institute
Doshisha Co Ltd
KUREI OKINAWA CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osaka Bioscience Institute, Doshisha Co Ltd, KUREI OKINAWA CO Ltd filed Critical Osaka Bioscience Institute
Priority to US12/602,013 priority Critical patent/US20100286415A1/en
Priority to CN2008800176603A priority patent/CN101711240B/zh
Priority to JP2009516358A priority patent/JP5354741B2/ja
Priority to EP08776987.3A priority patent/EP2168955B1/en
Publication of WO2008146883A1 publication Critical patent/WO2008146883A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

　本発明は新規な睡眠改善剤および鎮静剤を提供することを課題とする。 　上記課題は、以下の化学式（Ｉ）： ［化１］ で表されるオキシピナタニンまたはその誘導体を有効成分として含む睡眠改善剤および鎮静剤を提供することにより解決される。
PCT/JP2008/059925 2007-05-29 2008-05-29 睡眠改善剤 Ceased WO2008146883A1 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US12/602,013 US20100286415A1 (en) 2007-05-29 2008-05-29 Sleep-improving agent
CN2008800176603A CN101711240B (zh) 2007-05-29 2008-05-29 睡眠改善剂
JP2009516358A JP5354741B2 (ja) 2007-05-29 2008-05-29 睡眠改善剤
EP08776987.3A EP2168955B1 (en) 2007-05-29 2008-05-29 Sleep-improving agent

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-141608 2007-05-29
JP2007141608 2007-05-29

Publications (1)

Publication Number Publication Date
WO2008146883A1 true WO2008146883A1 (ja) 2008-12-04

Family

ID=40075116

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/059925 Ceased WO2008146883A1 (ja) 2007-05-29 2008-05-29 睡眠改善剤

Country Status (5)

Country Link
US (1) US20100286415A1 (ja)
EP (2) EP2168955B1 (ja)
JP (1) JP5354741B2 (ja)
CN (2) CN101711240B (ja)
WO (1) WO2008146883A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021112176A1 (ja) * 2019-12-03 2021-06-10 株式会社クレイ沖縄 睡眠の質向上用組成物

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100286415A1 (en) * 2007-05-29 2010-11-11 Osaka Bioscience Institute Sleep-improving agent
US20140248383A1 (en) * 2011-10-06 2014-09-04 Lion Corporation Sleep quality improving agent
CN105455140A (zh) * 2015-10-30 2016-04-06 上海善力健生物科技有限公司 一种用于改善睡眠的生物制剂及其制备方法
JP7381000B2 (ja) * 2016-05-26 2023-11-15 株式会社アミノアップ 睡眠改善剤

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11158077A (ja) * 1997-12-02 1999-06-15 Nissei Marine Kogyo Kk ストレス軽減効果のある組成物
WO2001058435A1 (en) * 2000-02-10 2001-08-16 Kao Corporation Autonomic controlling agents
JP2005206597A (ja) * 2003-12-26 2005-08-04 Osaka Industrial Promotion Organization 鎮静・安眠用組成物、鎮静・安眠材、及びそれを用いた付香製品
JP2006062998A (ja) 2004-08-25 2006-03-09 Ryukyu Bio Resource Kaihatsu:Kk 睡眠改善剤
WO2007013581A1 (ja) * 2005-07-28 2007-02-01 Kobayashi Pharmaceutical Co., Ltd. 鎮静用組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955495A (en) * 1996-05-03 1999-09-21 Hoffmann-La Roche Inc. Method of treating diseases of the CNS
US20100286415A1 (en) * 2007-05-29 2010-11-11 Osaka Bioscience Institute Sleep-improving agent

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11158077A (ja) * 1997-12-02 1999-06-15 Nissei Marine Kogyo Kk ストレス軽減効果のある組成物
WO2001058435A1 (en) * 2000-02-10 2001-08-16 Kao Corporation Autonomic controlling agents
JP2005206597A (ja) * 2003-12-26 2005-08-04 Osaka Industrial Promotion Organization 鎮静・安眠用組成物、鎮静・安眠材、及びそれを用いた付香製品
JP2006062998A (ja) 2004-08-25 2006-03-09 Ryukyu Bio Resource Kaihatsu:Kk 睡眠改善剤
WO2007013581A1 (ja) * 2005-07-28 2007-02-01 Kobayashi Pharmaceutical Co., Ltd. 鎮静用組成物

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
GANENKO T., SEMENOV A.A., ZINCHENKO S.V.: "Oxypinnatanine from roots of Stellaria dichotoma L", RASTITEL'NYE RESURSY, vol. 38, no. 3, 2002, pages 67 - 70 *
GREBNEVA N.Y., LESIOVSKAYA E.E, KHARITONOVA N.P.: "Some pharmacologcial properties of aqueous extracts of roots of Stellaria dichotoma", RASTITEL'NYE RESURSY, vol. 32, no. 4, 1996, pages 53 - 59 *
HUANG Z. L. ET AL., J. NEUROSCI., vol. 23, no. 14, 2003, pages 5975 - 83
INOUE TOMOHIRO ET AL.: "Novel 2,5-dihydrofuryl-gamma-lactam derivatives from Hemerocallis fulva L. var. kwanzo Regel", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 38, no. 11, 1990, pages 3187 - 3189, XP008127343 *
KRUGER G.J. ET AL.: "The Structure of N5-(3-Hydroxymethyl-2,5-Dihydro-2-Furyl)-L-Allo-gamma-Hydroxyglutamine, A New Amino Acif from HEMEROCALLIS FULVA L. (DAY LILY)", JOURNAL OF THE SOUTH AFRICAN CHEMICAL INSTITUTE, vol. XXIX, 1976, pages 24 - 29, XP008127345 *
OKADA T. ET AL., BIOCHEM. BIOPHYS. RES. COMMUN., vol. 312, no. 1, 2003, pages 29 - 34
UEZU, E.: "Effect of Hemerocallis on sleep in mice", PSYCHIATRY CLIN. NEUROSCI., vol. 52, no. 2, 1998, pages 136 - 137, XP008141350, DOI: doi:10.1111/j.1440-1819.1998.tb00992.x

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021112176A1 (ja) * 2019-12-03 2021-06-10 株式会社クレイ沖縄 睡眠の質向上用組成物
JPWO2021112176A1 (ja) * 2019-12-03 2021-06-10
JP2024150771A (ja) * 2019-12-03 2024-10-23 株式会社クレイ沖縄 睡眠の質向上用組成物

Also Published As

Publication number Publication date
CN103284991B (zh) 2015-09-09
CN103284991A (zh) 2013-09-11
EP2168955B1 (en) 2014-03-05
US20100286415A1 (en) 2010-11-11
JPWO2008146883A1 (ja) 2010-08-19
EP2168955A1 (en) 2010-03-31
EP2168955A4 (en) 2010-07-28
CN101711240B (zh) 2013-06-05
JP5354741B2 (ja) 2013-11-27
CN101711240A (zh) 2010-05-19
EP2650288A1 (en) 2013-10-16

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