WO2008140546A2 - Ensemble à réutilisation limitée destiné à un dispositif d'injection ophtalmique - Google Patents
Ensemble à réutilisation limitée destiné à un dispositif d'injection ophtalmique Download PDFInfo
- Publication number
- WO2008140546A2 WO2008140546A2 PCT/US2007/080666 US2007080666W WO2008140546A2 WO 2008140546 A2 WO2008140546 A2 WO 2008140546A2 US 2007080666 W US2007080666 W US 2007080666W WO 2008140546 A2 WO2008140546 A2 WO 2008140546A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- assembly
- actuator
- controller
- interface
- limited reuse
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14526—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons the piston being actuated by fluid pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14546—Front-loading type injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
- A61M5/445—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media the media being heated in the reservoir, e.g. warming bloodbags
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3368—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6027—Electric-conductive bridges closing detection circuits, with or without identifying elements, e.g. resistances, zener-diodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0612—Eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1413—Modular systems comprising interconnecting elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
Definitions
- Figure 2 is one view of an ophthalmic medical device including a disposable tip segment and a limited reuse assembly according to an embodiment of the present invention.
- controller 305 controls the operation of actuator 515.
- actuator 515 When actuator 515 is actuated, actuator shaft 510 is moved upward toward needle 210.
- mechanical linkage interface 545 which is mated with plunger interface 420, moves plunger 415 upward toward needle 210. A substance located in dispensing chamber 405 is then expelled through needle 210.
- disposable tip segment 205 includes housing 215, needle 210, plunger 415, plunger interface 420, dispensing chamber 405, dispensing chamber housing 425, assembly 555, temperature control device 450, thermal sensor 460, optional luer 430, tip interface connectors 451, 452, and 453, and interfaces 461, 462, and 463. Disposable tip segment 205 operates as a disposable injection device.
- temperature control device In various embodiments of the present invention, temperature control device
- any other type of wireless system can be used to transfer information between a limited reuse assembly 250 and tip segment 205.
- a Bluetooth protocol maybe used to establish a communications link between a limited reuse assembly 250 and tip segment 205.
- Information can then be transferred between a limited reuse assembly 250 and a tip segment 205 over this communication link.
- Other embodiments used to transfer information include an infrared protocol, 802.11, fire wire, or other wireless protocol.
- a number of different drug delivery tip segments 205 maybe manufactured and loaded with a drug at the factory. Dosage information can also be loaded onto RFID tag 1110 (or assembly 555) at the factory. In such a case, a number of different tip segments each
- Figure 1OB shows one of many different configurations for thermal sensor 460.
- thermal sensor 460 is connected to connectors 451 and 454. Signals are received from thermal sensor 460 through connectors 451 and 454.
- FIG. 1OC shows one of many different configurations for a fuse 1011.
- Fuse 1011 may be contained within assembly 555 or may be implemented as shown in Figure 1OC.
- fuse 1011 is connected between connectors 453 and 456.
- fuse 1011 acts to ensure that the tip assembly is a single-use device.
- Fuse 1011 is blown when the heat button is activated or after disposable tip segment 205 is used.
- a controller in a limited reuse assembly detects when the connected tip segment has been used and directs an increased current to pass through fuse 1011 thus blowing the fuse. When fuse 1011 is blown, the tip segment is no longer operable and must be discarded.
- Figure 1OD shows one of many different configurations for assembly 555.
- assembly 555 is connected to connectors 453 and 456.
- Power and/or control signals are provided to assembly 555 through connectors 453 and 456.
- connectors 451, 452 453, 454, 455, and 456 may be implemented.
- six connectors are shown, any number of connectors may be implemented.
- any combination of different circuits may be contained in a tip segment.
- INCORPORATED BY REFERENCE (RULE 20.6) measure the distance that actuator shaft 510 travels and a device to detect if actuator 515 stalls.
- controller 444 includes circuitry that may perform any of a number of different functions related to the charging, monitoring, and maintenance of power source 505. In other embodiments, power source controller 444 may be implemented in or integrated into controller 305.
- Figure 20 is a flow chart of one method relating to injecting a substance into an eye according to the principles of the present invention.
- Figure 20 relates to the situation in which the actuator shaft has stalled.
- the actuator is controlled based on a dosage and dosage rate information.
- the actuator moves the plunger to deliver the substance.
- data is received from a stall sensor.
- this data is used to determine if the actuator shaft has stalled. If the shaft has stalled, then in 2040, an indication of the stall condition is provided.
- data is received from a displacement sensor indicating the distance that the actuator shaft moved.
- an indication of the delivered dosage is provided based on the distance information. If the shaft has not stalled, then in 2070, an indication is provided that the proper dosage has been delivered.
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Ophthalmology & Optometry (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Prostheses (AREA)
Abstract
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2009003719A MX2009003719A (es) | 2006-10-16 | 2007-10-08 | Ensamble de reuso limitado para dispositivo de inyeccion oftalmica. |
| EP07874212A EP2068792A2 (fr) | 2006-10-16 | 2007-10-08 | Ensemble à réutilisation limitée destiné à un dispositif d'injection ophtalmique |
| CA002665377A CA2665377A1 (fr) | 2006-10-16 | 2007-10-08 | Ensemble a reutilisation limitee destine a un dispositif d'injection ophtalmique |
| AU2007353378A AU2007353378A1 (en) | 2006-10-16 | 2007-10-08 | Limited reuse assembly for ophthalmic injection device |
| JP2009533440A JP2010535040A (ja) | 2007-08-01 | 2008-06-17 | 眼科用注射器具のための再使用制限アセンブリ |
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92149806P | 2006-10-16 | 2006-10-16 | |
| US92149706P | 2006-10-16 | 2006-10-16 | |
| US92149906P | 2006-10-16 | 2006-10-16 | |
| US60/921,498 | 2006-10-16 | ||
| US11/581,630 | 2006-10-16 | ||
| US60/921,497 | 2006-10-16 | ||
| US11/581,591 | 2006-10-16 | ||
| US60/921,499 | 2006-10-16 | ||
| US11/832,364 | 2007-08-01 | ||
| US11/832,364 US20070270744A1 (en) | 2006-05-17 | 2007-08-01 | Limited Reuse Assembly For Ophthalmic Injection Device |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| WO2008140546A2 true WO2008140546A2 (fr) | 2008-11-20 |
| WO2008140546A3 WO2008140546A3 (fr) | 2009-07-23 |
| WO2008140546A8 WO2008140546A8 (fr) | 2010-07-22 |
Family
ID=44771591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2007/080666 Ceased WO2008140546A2 (fr) | 2006-10-16 | 2007-10-08 | Ensemble à réutilisation limitée destiné à un dispositif d'injection ophtalmique |
Country Status (2)
| Country | Link |
|---|---|
| TW (1) | TW200824662A (fr) |
| WO (1) | WO2008140546A2 (fr) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010017430A3 (fr) * | 2008-08-08 | 2010-06-17 | Mallinckrodt Inc. | Retour au repos automatique d'un injecteur |
| US9770562B2 (en) | 2011-05-06 | 2017-09-26 | Sanofi-Aventis Deutschland Gmbh | Lock out member with different cross sections |
| GB2565904A (en) * | 2017-11-03 | 2019-02-27 | Surgical Dynamics Ltd | Obstetric forceps |
| WO2019099322A1 (fr) * | 2017-11-16 | 2019-05-23 | Amgen Inc. | Auto-injecteur avec détection de décrochage et de point d'extrémité |
| WO2019162222A1 (fr) * | 2018-02-26 | 2019-08-29 | Haselmeier Ag | Détermination de dosage à l'aide de la conductivité électrique dans un dispositif d'injection |
| US20220096744A1 (en) * | 2020-09-29 | 2022-03-31 | Enclear Therapies, Inc. | Subarachnoid fluid management method and system |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10182939B2 (en) * | 2015-09-16 | 2019-01-22 | Novartis Ag | Hydraulic injector and methods for intra-ocular lens insertion |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5066276A (en) * | 1988-06-21 | 1991-11-19 | Alcon Laboratories, Inc. | Method and apparatus for injecting viscous fluid into the eye to lift pre-retinal and post-retinal membrane with linear pressure control |
| CA2129284C (fr) * | 1993-11-24 | 1999-03-09 | Kenneth J. Niehoff | Regulation de l'entrainement du plongeur pour l'injection de liquides a des animaux |
| US5733256A (en) * | 1996-09-26 | 1998-03-31 | Micro Medical Devices | Integrated phacoemulsification system |
| AU4565299A (en) * | 1998-06-15 | 2000-01-05 | Medrad, Inc. | Encoding of syringe information |
| US6595979B1 (en) * | 2001-07-10 | 2003-07-22 | Myocardial Therapeutics, Inc. | Methods for sterile aspiration/reinjection of bodily fluid |
| US7507221B2 (en) * | 2004-10-13 | 2009-03-24 | Mallinckrodt Inc. | Powerhead of a power injection system |
-
2007
- 2007-10-08 WO PCT/US2007/080666 patent/WO2008140546A2/fr not_active Ceased
- 2007-10-15 TW TW096138456A patent/TW200824662A/zh unknown
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2327432A1 (fr) * | 2008-08-08 | 2011-06-01 | Mallinckrodt, Inc. | Auto-direction de vérin d'injecteur automatique |
| US9044538B2 (en) | 2008-08-08 | 2015-06-02 | Liebel-Flarsheim Company Llc | Automatic injector ram homing |
| WO2010017430A3 (fr) * | 2008-08-08 | 2010-06-17 | Mallinckrodt Inc. | Retour au repos automatique d'un injecteur |
| US9770562B2 (en) | 2011-05-06 | 2017-09-26 | Sanofi-Aventis Deutschland Gmbh | Lock out member with different cross sections |
| GB2565904A (en) * | 2017-11-03 | 2019-02-27 | Surgical Dynamics Ltd | Obstetric forceps |
| GB2565904B (en) * | 2017-11-03 | 2020-01-29 | Obs One Ltd | Obstetric forceps |
| IL273636B1 (en) * | 2017-11-16 | 2025-06-01 | Amgen Inc | Autoinjector with stall and end point detection |
| WO2019099322A1 (fr) * | 2017-11-16 | 2019-05-23 | Amgen Inc. | Auto-injecteur avec détection de décrochage et de point d'extrémité |
| US11213626B2 (en) | 2017-11-16 | 2022-01-04 | Amgen Inc. | Autoinjector with stall and end point detection |
| IL273636B2 (en) * | 2017-11-16 | 2025-10-01 | Amgen Inc | Automatic injector with delay and end point sensing |
| AU2018368338B2 (en) * | 2017-11-16 | 2024-07-25 | Amgen Inc. | Autoinjector with stall and end point detection |
| WO2019162222A1 (fr) * | 2018-02-26 | 2019-08-29 | Haselmeier Ag | Détermination de dosage à l'aide de la conductivité électrique dans un dispositif d'injection |
| US12329930B2 (en) * | 2020-09-29 | 2025-06-17 | Enclear Therapies, Inc. | Subarachnoid fluid management method and system |
| US12337140B2 (en) | 2020-09-29 | 2025-06-24 | Enclear Therapies, Inc. | Subarachnoid fluid management method and system with varying rates |
| US20220096744A1 (en) * | 2020-09-29 | 2022-03-31 | Enclear Therapies, Inc. | Subarachnoid fluid management method and system |
Also Published As
| Publication number | Publication date |
|---|---|
| TW200824662A (en) | 2008-06-16 |
| WO2008140546A3 (fr) | 2009-07-23 |
| WO2008140546A8 (fr) | 2010-07-22 |
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| EP2068792A2 (fr) | Ensemble à réutilisation limitée destiné à un dispositif d'injection ophtalmique | |
| TW200824664A (en) | Ophthalmic injection system |
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