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WO2008035192A3 - Method of preparation of amorphous rabeprazole sodium - Google Patents

Method of preparation of amorphous rabeprazole sodium Download PDF

Info

Publication number
WO2008035192A3
WO2008035192A3 PCT/IB2007/002739 IB2007002739W WO2008035192A3 WO 2008035192 A3 WO2008035192 A3 WO 2008035192A3 IB 2007002739 W IB2007002739 W IB 2007002739W WO 2008035192 A3 WO2008035192 A3 WO 2008035192A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
rabeprazole sodium
amorphous rabeprazole
sodium
amorphous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2007/002739
Other languages
French (fr)
Other versions
WO2008035192A8 (en
WO2008035192A2 (en
Inventor
Indravadan Ambalal Modi
Brijesh Nitinbhai Kapadia
Amar Kiritbhai Parekh
Sanjay Natvarlal Parikh
Amarsingh L Rajput
Ravi Ponnaiah
Bakulesh Mafatlal Khamar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cadila Pharmaceuticals Ltd
Original Assignee
Cadila Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Pharmaceuticals Ltd filed Critical Cadila Pharmaceuticals Ltd
Publication of WO2008035192A2 publication Critical patent/WO2008035192A2/en
Publication of WO2008035192A8 publication Critical patent/WO2008035192A8/en
Anticipated expiration legal-status Critical
Publication of WO2008035192A3 publication Critical patent/WO2008035192A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to preparation of amorphous rabeprazole sodium from rabeprazole using sodium tertiary butoxide in tertiary butyl alcohol. The preparation further avoids the use of halogenated solvents, and freeze drying.
PCT/IB2007/002739 2006-09-22 2007-09-21 Method of preparation of amorphous rabeprazole sodium Ceased WO2008035192A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1518/MUM/2006 2006-09-22
IN1518MU2006 2006-09-22

Publications (3)

Publication Number Publication Date
WO2008035192A2 WO2008035192A2 (en) 2008-03-27
WO2008035192A8 WO2008035192A8 (en) 2008-05-29
WO2008035192A3 true WO2008035192A3 (en) 2009-04-23

Family

ID=39200897

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/002739 Ceased WO2008035192A2 (en) 2006-09-22 2007-09-21 Method of preparation of amorphous rabeprazole sodium

Country Status (1)

Country Link
WO (1) WO2008035192A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060135565A1 (en) * 2004-12-21 2006-06-22 Dipharma S.P.A. Crystalline form of rabeprazole sodium

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060135565A1 (en) * 2004-12-21 2006-06-22 Dipharma S.P.A. Crystalline form of rabeprazole sodium

Also Published As

Publication number Publication date
WO2008035192A8 (en) 2008-05-29
WO2008035192A2 (en) 2008-03-27

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