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WO2008021981A3 - Local treatment of epidermal and dermal hyperproliferative lesions - Google Patents

Local treatment of epidermal and dermal hyperproliferative lesions Download PDF

Info

Publication number
WO2008021981A3
WO2008021981A3 PCT/US2007/075624 US2007075624W WO2008021981A3 WO 2008021981 A3 WO2008021981 A3 WO 2008021981A3 US 2007075624 W US2007075624 W US 2007075624W WO 2008021981 A3 WO2008021981 A3 WO 2008021981A3
Authority
WO
WIPO (PCT)
Prior art keywords
epidermal
local treatment
lesion
dermal hyperproliferative
hyperproliferative lesions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/075624
Other languages
French (fr)
Other versions
WO2008021981A2 (en
Inventor
Ruihong Chen
Allan E Rubenstein
Xiaodong Shen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nexgenix Pharmaceuticals LLC
Original Assignee
Nexgenix Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexgenix Pharmaceuticals LLC filed Critical Nexgenix Pharmaceuticals LLC
Publication of WO2008021981A2 publication Critical patent/WO2008021981A2/en
Publication of WO2008021981A3 publication Critical patent/WO2008021981A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A method for treating at least one epidermal or dermal hyperproliferative lesion in a subject in need of such treatment is disclosed. The method comprises locally applying a composition to a lesion either topically or intralesionally or via local delivery to the region in proximity to the lesion. Compositions useful for such treatments and methods of preparing the compositions are disclosed.
PCT/US2007/075624 2006-08-09 2007-08-09 Local treatment of epidermal and dermal hyperproliferative lesions Ceased WO2008021981A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83636606P 2006-08-09 2006-08-09
US60/836,366 2006-08-09

Publications (2)

Publication Number Publication Date
WO2008021981A2 WO2008021981A2 (en) 2008-02-21
WO2008021981A3 true WO2008021981A3 (en) 2008-08-28

Family

ID=39082975

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/075624 Ceased WO2008021981A2 (en) 2006-08-09 2007-08-09 Local treatment of epidermal and dermal hyperproliferative lesions

Country Status (1)

Country Link
WO (1) WO2008021981A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ587207A (en) 2008-02-01 2012-05-25 Takeda Pharmaceutical Oxim derivatives as hsp90 inhibitors
US9592188B2 (en) 2014-05-22 2017-03-14 Yansong Liu Method of treating or reducing the severity of dermatological conditions
MX2018001073A (en) 2015-08-06 2018-06-12 Chimerix Inc Pyrrolopyrimidine nucleosides and analogs thereof useful as antiviral agents.
EP3681494A4 (en) * 2017-09-15 2021-08-04 Ampersand Biopharmaceuticals, Inc. Inhibition of spontaneous metastasis via protein inhibitors of cysteine proteases
WO2019055880A2 (en) 2017-09-15 2019-03-21 Ampersand Biopharmaceuticals, Inc. Method of administration and treatment
EP3684771B1 (en) 2017-09-21 2024-11-27 Chimerix, Inc. Morphic forms of 4-amino-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methyl-7h-pyrrolo(2,3-d)pyrimidine-5-carboxamide and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040253228A1 (en) * 2003-02-20 2004-12-16 Srivastava Pramod K. Methods for using compositions comprising heat shock proteins or alpha-2-macroglobulin in the treatment of cancer and infectious disease
US20060077601A1 (en) * 2004-09-30 2006-04-13 Hiroyuki Ikeda Semiconductor device
US20060165710A1 (en) * 2003-02-20 2006-07-27 University Of Connecticut Health Center Methods and compositions for the treatment of cancer and infectious disease using alpha (2) macroglobulin-antigenic molecule complexes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040253228A1 (en) * 2003-02-20 2004-12-16 Srivastava Pramod K. Methods for using compositions comprising heat shock proteins or alpha-2-macroglobulin in the treatment of cancer and infectious disease
US20060165710A1 (en) * 2003-02-20 2006-07-27 University Of Connecticut Health Center Methods and compositions for the treatment of cancer and infectious disease using alpha (2) macroglobulin-antigenic molecule complexes
US20060077601A1 (en) * 2004-09-30 2006-04-13 Hiroyuki Ikeda Semiconductor device

Also Published As

Publication number Publication date
WO2008021981A2 (en) 2008-02-21

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