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WO2008016666A3 - Certain chemical entities, compositions, and methods - Google Patents

Certain chemical entities, compositions, and methods Download PDF

Info

Publication number
WO2008016666A3
WO2008016666A3 PCT/US2007/017231 US2007017231W WO2008016666A3 WO 2008016666 A3 WO2008016666 A3 WO 2008016666A3 US 2007017231 W US2007017231 W US 2007017231W WO 2008016666 A3 WO2008016666 A3 WO 2008016666A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
chemical entities
compositions
certain chemical
muscle myosin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/017231
Other languages
French (fr)
Other versions
WO2008016666A2 (en
Inventor
Xiangping Qian
Jeffrey T Finer
Pu-Ping Lu
Chihyuan Grace Chuang
Bradley P Morgan
David J Morgans Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytokinetics Inc
Original Assignee
Cytokinetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytokinetics Inc filed Critical Cytokinetics Inc
Publication of WO2008016666A2 publication Critical patent/WO2008016666A2/en
Publication of WO2008016666A3 publication Critical patent/WO2008016666A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
PCT/US2007/017231 2006-08-02 2007-08-01 Certain chemical entities, compositions, and methods Ceased WO2008016666A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83523706P 2006-08-02 2006-08-02
US60/835,237 2006-08-02

Publications (2)

Publication Number Publication Date
WO2008016666A2 WO2008016666A2 (en) 2008-02-07
WO2008016666A3 true WO2008016666A3 (en) 2008-07-24

Family

ID=38997710

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/017231 Ceased WO2008016666A2 (en) 2006-08-02 2007-08-01 Certain chemical entities, compositions, and methods

Country Status (1)

Country Link
WO (1) WO2008016666A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ589825A (en) 2008-06-19 2012-11-30 Takeda Pharmaceutical Heterocyclic compound and use thereof
EP3193600A4 (en) * 2014-09-10 2018-05-23 Epizyme, Inc. Smyd inhibitors
WO2020097398A1 (en) 2018-11-07 2020-05-14 Dana-Farber Cancer Institute, Inc. Benzothiazole derivatives and 7-aza-benzothiazole derivatives as janus kinase 2 inhibitors and uses thereof
CN115151540A (en) 2019-12-02 2022-10-04 风暴治疗有限公司 Polyheterocyclic compounds as METTL3 inhibitors
US11691963B2 (en) 2020-05-06 2023-07-04 Ajax Therapeutics, Inc. 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors
US12043632B2 (en) 2020-12-23 2024-07-23 Ajax Therapeutics, Inc. 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors
EP4430042A1 (en) 2021-11-09 2024-09-18 Ajax Therapeutics, Inc. 6-he tero aryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors
TW202325289A (en) 2021-11-09 2023-07-01 美商雅捷可斯治療公司 Forms and compositions of inhibitors of jak2

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070135435A1 (en) * 2005-11-02 2007-06-14 Xiangping Qian Certain chemical entities, compositions, and methods
US20070293530A1 (en) * 2006-06-14 2007-12-20 Methylgene Inc. Sulfamide and sulfamate derivatives as histone deacetylase inhibitors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070135435A1 (en) * 2005-11-02 2007-06-14 Xiangping Qian Certain chemical entities, compositions, and methods
US20070293530A1 (en) * 2006-06-14 2007-12-20 Methylgene Inc. Sulfamide and sulfamate derivatives as histone deacetylase inhibitors

Also Published As

Publication number Publication date
WO2008016666A2 (en) 2008-02-07

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