[go: up one dir, main page]

WO2008007359A3 - Rapid diagnostic devices based on molecular imprinted polymers - Google Patents

Rapid diagnostic devices based on molecular imprinted polymers Download PDF

Info

Publication number
WO2008007359A3
WO2008007359A3 PCT/IL2007/000851 IL2007000851W WO2008007359A3 WO 2008007359 A3 WO2008007359 A3 WO 2008007359A3 IL 2007000851 W IL2007000851 W IL 2007000851W WO 2008007359 A3 WO2008007359 A3 WO 2008007359A3
Authority
WO
WIPO (PCT)
Prior art keywords
imprinted polymers
devices based
diagnostic devices
rapid diagnostic
molecular imprinted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2007/000851
Other languages
French (fr)
Other versions
WO2008007359A2 (en
Inventor
Raphael Levi
Ido Margalit
Yarden Dloomy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INFIGO DIAGNOSTICS Ltd
Original Assignee
INFIGO DIAGNOSTICS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INFIGO DIAGNOSTICS Ltd filed Critical INFIGO DIAGNOSTICS Ltd
Priority to EP07766881A priority Critical patent/EP2041567A4/en
Publication of WO2008007359A2 publication Critical patent/WO2008007359A2/en
Priority to IL196223A priority patent/IL196223A0/en
Anticipated expiration legal-status Critical
Publication of WO2008007359A3 publication Critical patent/WO2008007359A3/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54391—Immunochromatographic test strips based on vertical flow

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention pertains generally to sensitive diagnostic assay devices, methods and kits for determining the presence, absence and/or amount of analytes in fluid samples The devices (figures 3a & 3b) are based on molecularly imprinted polymers (MlPs) for use in real¬ time measurements of levels of analytes, particularly small molecules, in fluid samples One such device is a device for determination of B12 (cobalamin) deficiency or methylmalonic aciduria by measuring methylmalonic acid (MVA) in either blood or urine.
PCT/IL2007/000851 2006-07-09 2007-07-08 Rapid diagnostic devices based on molecular imprinted polymers Ceased WO2008007359A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07766881A EP2041567A4 (en) 2006-07-09 2007-07-08 Rapid diagnostic devices based on molecular imprinted polymers
IL196223A IL196223A0 (en) 2006-07-09 2008-12-25 Rapid diagnostic devices based on molecular imprinted polymers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80678306P 2006-07-09 2006-07-09
US60/806,783 2006-07-09

Publications (2)

Publication Number Publication Date
WO2008007359A2 WO2008007359A2 (en) 2008-01-17
WO2008007359A3 true WO2008007359A3 (en) 2009-05-07

Family

ID=38923664

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2007/000851 Ceased WO2008007359A2 (en) 2006-07-09 2007-07-08 Rapid diagnostic devices based on molecular imprinted polymers

Country Status (2)

Country Link
EP (1) EP2041567A4 (en)
WO (1) WO2008007359A2 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101945990A (en) * 2007-12-27 2011-01-12 尹菲戈诊断有限公司 Small molecules and protein analysis devices based on molecular imprinted polymers
US20130137117A1 (en) * 2009-07-23 2013-05-30 Raphael Levi Method for preparing protein imprinted polymers and use thereof
US10451598B2 (en) 2010-09-10 2019-10-22 The Trustees Of Dartmouth College Devices for detecting airborne contaminants, and associated methods
US9429536B2 (en) 2010-09-10 2016-08-30 Trustees Of Dartmouth College Airborne contaminant sensor device and method for using the same
WO2012034115A1 (en) * 2010-09-10 2012-03-15 Trustees Of Dartmouth College Airborne contaminant sensor device and method for using the same
US11366077B2 (en) 2010-09-10 2022-06-21 The Trustees Of Dartmouth College Systems, sensing devices and methods for detection of airborne contaminants
CN102478575A (en) * 2010-11-29 2012-05-30 内蒙古蒙牛乳业（集团）股份有限公司 Method for evaluating effectiveness of kanamycin test strip in dairy product detection
CN102478574A (en) * 2010-11-29 2012-05-30 内蒙古蒙牛乳业（集团）股份有限公司 Method for evaluating effectiveness of streptomycin test strip in dairy product detection
CN102331503A (en) * 2011-08-31 2012-01-25 内蒙古科慧生物科技有限责任公司 Quantitative testosterone (T) measurement kit and detection method thereof
CN102426251A (en) * 2011-08-31 2012-04-25 内蒙古科慧生物科技有限责任公司 Quantitative determination kit for progesterone and detection method thereof
WO2013033383A2 (en) 2011-08-31 2013-03-07 The Trustees Of Dartmouth College Molecularly imprinted polymers for detection of contaminants
CN102393448B (en) * 2011-10-20 2015-06-03 东北大学 Method for selectively and quantitatively collecting Cd in water environment
CN102507261B (en) * 2011-10-20 2015-06-03 东北大学 Method for selectively and quantitatively collecting arsenic in water environment
CN102520193B (en) * 2011-12-29 2014-08-13 深圳康美生物科技股份有限公司 Fluorescence immunochromatographic assay and kit for quantitative detection of human cardiac troponin I (cTnI)
WO2016080998A1 (en) * 2014-11-20 2016-05-26 Monolythix, Inc. Monoliths
US9464969B2 (en) 2014-11-20 2016-10-11 Monolythix, Inc. Monoliths
US9782771B2 (en) 2015-01-16 2017-10-10 Xerox Corporation Method for making hydrophobic barriers requiring UV-light treatment
US10570439B2 (en) 2015-08-18 2020-02-25 Monolythix, Inc. Sample concentration devices
WO2017111692A1 (en) * 2015-12-21 2017-06-29 Stockholm University A solid form sampling tablet and its use for determining the amount of a specific analyte in a liquid sample.
CN108107223A (en) * 2016-11-24 2018-06-01 温州科技职业学院 Detect method and its enzyme linked immunological kit used of estradiol and/or oestradiol benzoate
DE102017129476B4 (en) * 2017-12-11 2024-04-18 Bundesrepublik Deutschland, vertreten durch die Bundesministerin für Wirtschaft und Energie, diese vertreten durch den Präsidenten der Bundesanstalt für Materialforschung und-prüfung (BAM) Label-free optical detection in capture zones immobilized on strips for lateral flow assays
CN112485430B (en) * 2020-11-13 2023-08-11 北京勤邦科技股份有限公司 Application of alachlor artificial antigen in ELISA kit
CN114689847B (en) * 2022-03-07 2023-07-18 西南大学 A novel lateral flow chromatography test strip based on molecular imprinting, its preparation method and its application in the detection of small molecule thiodiglycol

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573921A (en) * 1992-09-04 1996-11-12 Dragerwerk Aktiengesellschaft Immunochemical displacement for determining an analyte
US5786220A (en) * 1995-04-28 1998-07-28 Quidel Corporation Assays and devices for distinguishing between normal and abnormal pregnancy
US6660176B2 (en) * 2001-01-24 2003-12-09 Virginia Commonwealth University Molecular imprinting of small particles, and production of small particles from solid state reactants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2092523T3 (en) * 1990-05-09 1996-12-01 Abbott Lab TRIALS USING LINKS WITH CONJUGATE RECOVERY.
US5874216A (en) * 1996-02-23 1999-02-23 Ensys Environmental Products, Inc. Indirect label assay device for detecting small molecules and method of use thereof
CA2309384A1 (en) * 1997-11-06 1999-05-20 Mosaic Technologies Multiple sequential polynucleotide displacement reactions for signal amplification and processing
SE0001877D0 (en) * 2000-05-22 2000-05-22 Klaus Mosbach Molecular imprinting

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573921A (en) * 1992-09-04 1996-11-12 Dragerwerk Aktiengesellschaft Immunochemical displacement for determining an analyte
US5786220A (en) * 1995-04-28 1998-07-28 Quidel Corporation Assays and devices for distinguishing between normal and abnormal pregnancy
US6660176B2 (en) * 2001-01-24 2003-12-09 Virginia Commonwealth University Molecular imprinting of small particles, and production of small particles from solid state reactants

Also Published As

Publication number Publication date
EP2041567A4 (en) 2011-04-13
WO2008007359A2 (en) 2008-01-17
EP2041567A2 (en) 2009-04-01

Similar Documents

Publication Publication Date Title
WO2008007359A3 (en) Rapid diagnostic devices based on molecular imprinted polymers
WO2008070865A3 (en) Materials and methods for efficient and accurate detection of analytes
EP1359417A3 (en) Devices and methods for analyte concentration determination
WO2008014132A3 (en) Combination analyte measurement device and method of use
WO2008021290A3 (en) Organ-specific proteins and methods of their use
WO2009058902A3 (en) Methods and devices for analyte detection
ATE438853T1 (en) DIAGNOSTIC TEST APPARATUS
NO20076656L (en) Improved immunoassay methods
WO2008075217A3 (en) Lateral flow assay device and absorbent article containing same
SG169968A1 (en) Adhesive composition for use in an immunosensor
RU2010136021A (en) SYSTEM FOR DETECTING ANALYTES IN BODY LIQUID
CY1113686T1 (en) BIO-SENSOR DEVICE AND ITS METHODS OF USE
WO2007127749A3 (en) Predicting mortality and detecting severe disease
NZ590930A (en) Improving the calibration accuracy of a fluidic system by comparing test readings with a calibration curve and then adjusting the signal output
EP1957989A4 (en) DEVICE FOR DETECTING THE PRESENCE OR QUANTITY OF AN ANALYTE IN A FLUID SAMPLE, AND ASSOCIATED METHOD
WO2006079049A3 (en) Methods and compositions for increased dynamic range detection of nucleic acid molecules
WO2004063713A3 (en) Non-invasive determination of direction and rate of change of an analyte
MX2009006159A (en) Test element with referencing.
WO2008131361A3 (en) Biosensors for measuring analytes in the interstitial fluid
MY162697A (en) Methods, devices and kits for detecting or monitoring acute kidney injury
WO2006105110A3 (en) Assay device and methods
MX369024B (en) Reducing optical interference in a fluidic device.
WO2005093414A3 (en) Assay devices utilizing chemichromic dyes
ATE532063T1 (en) ELECTROCHEMICAL BIOSENSOR
BR112015011040A2 (en) test calibration using reaction time

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07766881

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 196223

Country of ref document: IL

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2007766881

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: RU