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WO2008005016A1 - timbre de surveillance cardiaque jetable à port prolongé - Google Patents

timbre de surveillance cardiaque jetable à port prolongé Download PDF

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Publication number
WO2008005016A1
WO2008005016A1 PCT/US2006/026249 US2006026249W WO2008005016A1 WO 2008005016 A1 WO2008005016 A1 WO 2008005016A1 US 2006026249 W US2006026249 W US 2006026249W WO 2008005016 A1 WO2008005016 A1 WO 2008005016A1
Authority
WO
WIPO (PCT)
Prior art keywords
patch
ecg
electrodes
cardiac
processor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/026249
Other languages
English (en)
Inventor
Adnan Shennib
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CardioVu Inc
Original Assignee
CardioVu Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CardioVu Inc filed Critical CardioVu Inc
Priority to PCT/US2006/026249 priority Critical patent/WO2008005016A1/fr
Publication of WO2008005016A1 publication Critical patent/WO2008005016A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/251—Means for maintaining electrode contact with the body
    • A61B5/257—Means for maintaining electrode contact with the body using adhesive means, e.g. adhesive pads or tapes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/333—Recording apparatus specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/333—Recording apparatus specially adapted therefor
    • A61B5/338—Recording by printing on paper
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6832—Means for maintaining contact with the body using adhesives
    • A61B5/6833—Adhesive patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0492—Patch electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0406—Constructional details of apparatus specially shaped apparatus housings
    • A61B2560/0412—Low-profile patch shaped housings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/046—Specially adapted for shock therapy, e.g. defibrillation

Definitions

  • the invention relates to electrocardiogram (ECG) detection. More particularly, this invention relates to non-invasive monitoring and detection of heart abnormalities.
  • Cardiovascular diseases are pervasive, contributing to over 2.4 million deaths annually in the United States alone. Patients suffering from heart disease often have no symptoms until a heart attack develops. Other symptoms are intermittent and often ignored after the resolution of the cardiac event. Delay in recognition and treatment of a heart disease leads to more damage to the heart, higher cost of hospitalization and lower quality of life for the survivors.
  • Certain heart abnormalities may be detected by standard ECG equipment available in hospitals and clinical settings. However, many other abnormalities are so intermittent and cannot be detected with typical in-clinic evaluations. Certain arrhythmias occur only a few times followed by a fatal heart attack. Syncope, or temporary loss of consciousness, is another common problem accounting for 3 percent of emergency room visits according to hospital reports. These cardiac abnormalities are illusive and may not be detected with current ECG systems, including Holter and cardiac event monitors.
  • Holter monitors are used for ambulatory monitoring and recording of
  • ECG ECG.
  • ECG ECG
  • These instruments typically use 5 or more ECG electrodes attached to the chest at one end and connected to a portable device at the other end.
  • the electronic device is worn or strapped to the body and records ECG signals in its memory.
  • Holter monitors may also incorporate an alarm to warn the patient of an adverse cardiac event. After typically 24 or 48 hours of monitoring, the Holter monitor is returned to the clinic, where the recorded ECG data are downloaded for review, record keeping, and for further analysis.
  • Sizable memory is typically required to record many hours of continuous ECG.
  • Cardiac event monitors record a few minutes of ECG that occur during an intermittent cardiac event, i.e. heart palpitation, dizziness, syncope, chest pain, etc.
  • cardiac event monitors There are generally two types of cardiac event monitors; (1) post-symptom event recorder and (2) looping memory (pre-symptom) recorder.
  • the postsymptom event recorder is simple to use and may be handheld and applied by the patient on the chest upon the occurrence of a cardiac event.
  • the metal feet allow conduction of the ECG signal into the monitor's memory. Since the recording is post-symptomatic, the cardiac events may be missed if too short or if there is a delay in the response by the patient.
  • the looping memory event recorder resolves the delay issue by pre- attaching the monitor to the patient's chest via two electrodes for the duration of monitoring.
  • These devices therefore continuously monitor the ECG and have the ability to retain the most recent segment of the ECG just prior to the activation of the recording switch. For example, when a patient experiences a palpitation, the device keeps in memory the prior 45 seconds of ECG as well as 15 seconds post the activation. With this method of monitoring, many transitory symptoms can be documented. A patient with symptoms of syncope would be given this type of monitor programmed to record several minutes before activation. This is to allow sufficient time for the person to recover from a faint episode, which may last several minutes.
  • These monitors may have a display to inform the patient if and how many events have been recorded and the status of the battery life.
  • Long-term cardiac monitoring is typically 30 days, although some patients with less frequent symptoms may be monitored for several months.
  • Holter monitors are generally more diagnostic than event recorders but are limited to 1 or 2 days of recording. Event recorders are less bulky and more comfortable to wear but lack the diagnostic capabilities of Holter monitors. Daily or periodic trans- telephonic data transmission of ECG data is employed for individuals who require long term monitoring of their ECG. The patches (electrodes) employed with these monitors are disposable. However, the electronic base unit is reusable as it is loaned to patients as part of the diagnostic service provided by the clinic.
  • ECG monitors that are not only expensive but also require additional specialized instruments comprising hardware and software to retrieve, store, and produce patient reports.
  • the cost and training requirement for these ambulatory ECG systems presents a major barrier for individuals and many in the medical community, particularly those not specializing in cardiac care.
  • the above prior art instruments and methods and others discussed below fall short of providing low cost effective long term cardiac monitoring.
  • U.S. patent application publication no. 2003/0069510 to Semler discloses a disposable vital signs monitor in the form of a patch that is a "flexible, nominally flat planer form having integral gel electrodes, a sticky-back rear surface, an internal flex circuit capable of sensing, recording, and play out several minutes of the most recently acquired ECG waveform data and a front surface that includes an output port preferably having one or more snap connectors compatible with lead harness ... .”
  • the monitor disclosed by Semler is designed for short term applications as stated: "a relatively short term battery life, as it is intended for limited-term use.” This and other limitations render Semler' s invention inadequate for long-term assessment of intermittent cardiac abnormalities.
  • U.S. patent No. 5,634,468 to Platt et al. discloses a sensor patch for obtaining physiologic data, including temperature, and transmitting a conditioned signal to a nearby portable unit and subsequently to a remote monitoring equipment.
  • Platt' s patch neither saves ECG data nor performs ECG analysis for detecting cardiac abnormalities. For these purposes, it relies on external devices as disclosed.
  • U.S. patent application publication no. 2003/0083559 to Thompson discloses a peripheral monitor patch for attachment to a patient including high capacity memory for storage and later retrieval of the sensed ECG data.
  • the patch comprises non- contact electrodes.
  • the disclosed patch neither provides diagnostic capability nor means for long term wear and monitoring.
  • the invention provides a disposable sensor patch for non-invasive monitoring and recording of intermittent cardiac events.
  • the patch is thin and flexible for comfortable wear on the person's chest for analysis and recording of ECG signals present on the surface of the body.
  • the self-adhered patch is inexpensive and simple for self- administration.
  • the patch incorporates a battery, ECG amplifier, and a processor for analyzing ECG waveform and recording events.
  • a software algorithm searches for a cardiac abnormality and records the corresponding ECG segment.
  • the patch is designed for continuous long-term wear. Li a preferred embodiment, a preformatted report is automatically generated by the patch and transmitted wirelessly to a generic reporting device such as a printer or a wireless network system using infrared or RF signals.
  • the patch may also incorporate a marker switch to correlate recorded ECG data with the patient' s perception of a cardiac event. Because of the extreme comfort of wear, a multi-lead configuration can be worn for periods exceeding 48 hours thus providing improved diagnostics when compared to standard Holter monitors. A single lead configuration, targeting arrhythmia detection, can be worn for at least 14 days and preferably 30 days or more, thus providing a non-invasive alternative to standard event recorders and implant monitors.
  • the patch is preferably treated with medication material to minimize possible contamination and infections of the skin since it is worn for extended periods.
  • the medication may include anti-bacterial, anti-microbial and like agents such as zinc oxide.
  • the invented patch is totally unobtrusive, comfortable to wear and waterproof for continuous uninterrupted wear, even during bathing.
  • the patch may also include an indicator for alerting the user of a detected event. This allows the user with suspected heart abnormality to wear several patches sequentially until a cardiac event is detected and recorded by the patch.
  • Fig. 1 is a view of the extended wear ECG monitor patch placed on the chest of a person
  • Fig.2 is a top view of the extended wear ECG monitor patch having 3 electrodes, flexible circuit, battery, recording switch and other major components;
  • FIG. 3 is a cross section view of the patch of Fig. 2, showing the various layers with thickness exaggerated for clarity;
  • Fig. 4 shows a two-electrode band-shaped embodiment
  • Fig. 5 shows an embodiment of the ECG patch with 4 electrodes and an LCD indicator
  • Fig. 6 shows a C-shaped multi-lead diagnostic embodiment of the patch
  • Fig. 7 shows the C-patch diagnostic embodiment of Fig. 6 placed on the chest and encompassing the left breast of a female;
  • Fig. 8 shows optical transmission of a preformatted ECG report to a printer device
  • Fig.9 shows wireless transmission of ECG data, recorded by the patch to a computer via a receiver wand.
  • the invention shown in various embodiments of Figs. 1-9 is a disposable non-invasive patch for detection of intermittent cardiac abnormalities.
  • the patch 10 is thin, flat, and flexible for placement on the chest area 2 of a person 1 whose heart is being examined for possible abnormality.
  • the sensor patch relies on a surface electrocardiogram (ECG) for detecting and analyzing non-invasively the electrical activity of the heart.
  • ECG surface electrocardiogram
  • the smart patch is fully self-contained and self-powered.
  • the patch analyzes the ECG for an extended period of time depending on the application. Patterns of ECG abnormalities are recorded automatically and a report is generated by the patch and transmitted to a reporting device directly.
  • the sensor patch is low cost for disposable applications and self-administration.
  • the sensor patch 10 comprises three ECG electrodes 21 , 22, and 23, an ECG amplifier 31 , a processor 33, and a battery 35.
  • the processor 33 is typically a microprocessor or a digital signal processor for performing numerical computation on data obtained from an analog-to-digital converter 32.
  • the sensor patch 10 also incorporates a memory 34, referring generally here to all types of solid-state memory for storage of program data and acquired ECG data.
  • a record switch 50 allows the user to record a cardiac event whenever felt
  • the electronic assembly of the patch is formed of a flexible circuit substrate 20 with trace extensions to the electrodes 21, 22, 23, and to the battery 35.
  • Conductive gel 25, 26 covers the electrodes 21 , 22, respectively, as well as the other electrode not shown in the view of Fig. 3.
  • the conductive gel 25 and 26 contacts the person's skin directly to conduct surface ECG potentials to the electrodes and subsequently to the ECG amplifier 31.
  • the electrodes may be pre-gelled as shown or alternately made for dry contact (not shown) with electrodes directly contacting the skin.
  • a non-conductive pad 27 electrically separates the electrodes and may comprise an adhesive gel, i.e. Hydrogel, for enhancing adhesion of the patch 10 to the skin.
  • the non-conductive pad 27 may also be made of soft low-durometer rubber or elastomeric material.
  • the patch 10 also comprises a thin substrate 28 for providing structural support.
  • the substrate 28 is made of soft flexible sheath material, such as polyurethane, cotton, cloth or made from the same material as the pad 27.
  • the thickness of the patch device 10 (not shown to scale for clarity) is preferably in the range of 1.5 and 2.5 mm, but preferably no more than 3 mm.
  • Non-conductive waterproof adhesive 39 present at the perimeter of the interior side of the patch prevents water entry and provides long term adhesion to the skin.
  • the waterproof skin adhesive 39 prevents contamination of electrodes thus maintaining long- term integrity of the skin-electrode electrical conductivity. This is critical for providing long term function of the monitor patch while allowing the user to be exposed to water such as during bathing and swimming.
  • the substrate 28, adhesive 39 and other materials used in the design of the patch are preferably air permeable with respect to the skin in order to prevent moisture accumulation and contamination due to perspiration.
  • Anti-microbial and antibacterial agents are preferably incorporated in the design of the patch, particularly at the skin contact areas, to prevent contamination of the patch and infection of the skin during the extended wear of the device.
  • the patch is self-adhered.
  • a porous and/or air permeable waterproof cover 29 protects the outer surface of the patch from external water exposure while allowing drying of the skin.
  • the extended wear heart monitor patch 10 comprises three ECG electrodes for placement on the heart area 3 as shown in Fig. 1.
  • the electrodes are arranged to provide a modified three-lead configuration with the electrodes 21, 22, 23 representing right arm (RA), left arm (LA) and left leg (LL) leads as in standard ECG instrumentation.
  • This configuration results in standard, direct lead measurements Lead-L, Lead-II, Lead-IU.
  • Other electrode placements and lead configurations are possible.
  • Fig. 4- shows a band-shaped patch 11 with a two-electrode embodiment, E 1 and E 2 , for sensing the surface ECG.
  • a multi-color LED 40 is used to indicate heart activity and event detection.
  • the invented patch is particularly suited to detect infrequent and rare events such as atrial fibrillation and syncope. These events often elude conventional ECG instruments. Since the invented patch is waterproof and can be worn continuously, even during showering and swimming, cardiac events are readily detected and documented. The detection occurs automatically and optionally manually. Automatic detection and recording occurs by continuously monitoring and analyzing ECG data by the processor 33. Manually recording is provided by an optional switch 50, which is activated when the patient becomes aware of a cardiac episode. The activation of the switch 50 triggers a recording session of a predetermined length, for example 3 minutes prior activation plus 2 minutes post activation. This method ensures detection and recording of even the most transient episodes such as syncope, which is accompanied by a temporary loss of consciousness.
  • cardiac abnormalities can be detected by comparing the characteristics of sensed ECG with predetermined limits and patterns. For example, shifts in certain segments of the ECG, such as the ST-segment, QT interval and QRS width, can be used to determine and record a cardiac event. By focusing on recording mostly cardiac events, memory size is reduced for producing smaller and more wearable device than those of conventional monitors.
  • a light emitting diode (LED) indicator 36 is provided.
  • the indictor many be multi-colored to indicate different levels of indication. For example, a blinking green LED light can indicate a normal heart function and while a red LED light indicates a cardiac event condition.
  • the LED can also be used to indicate proper path operation during the collection of ECG data. For example, the LED can be flashing in synchrony with QRS pulses upon proper placement of the smart patch and upon detection of ECG signals.
  • buttons include audible transducers, such as a buzzer
  • Fig. 5 shows a 4-electrode embodiment of the patch including a right leg (RL) electrode.
  • Fig. 6 & 7 show a nine-electrode patch 12 arranged in a "C" configuration.
  • the electrodes are arranged to obtain modified twelve-lead measurements, excluding the V6 lead.
  • This and other multi-lead configurations provide multi-axis or vectorcardiograph capability for improved diagnostics.
  • the electrodes 21, 22, 23, 24 offer binoiar frontal niane RCG (lead-I, II, and IQ) while electrodes 45, 46, 47, 48, and 49 offer unipolar precordial ECG, generally representing the horizontal plane, for leads Vl, V2, V3, V4, and V5, respectively.
  • the "C” patch encompasses the left breast 6 having an upper segment 42, lower segment 43, and sternum segment 44.
  • the "C” patch 12 is particularly suitable for fitting on a female 5 as shown in Fig. 7.
  • Electrodes are integrated within the patch of the invention, motion artifact is significantly reduced when compared to standard ECG with separate electrodes and cabling. Furthermore, the integrated patch allows for inconspicuous, convenient long-term ambulatory applications.
  • Multi-lead patch configurations are particularly suited for diagnostic monitoring extended beyond 24 to 48 hours offered by conventional Holter monitors. This is possible by the present invention for at least three reasons.
  • First, the invented patch is flexible and more comfortable to wear.
  • Third, the patch is waterproof thus can be worn continuously without removal.
  • Signal processing by processor 33 is particularly suited for performing signal averaging to enhance certain details of the sensed ECG.
  • Signal-averaged ECG involves the averaging of a large number of ECG periods, particularly for QRS, ST or QT segments, to enhance the detection of small fluctuations.
  • a unique feature of the present invention is the wireless transmission of preformatted report to a reporting device such as a printer or a wireless network. This allows for generation of a cardiac test report 53 without resorting to any specialized instruments.
  • Fig 8 shows the invented patch 10 having an infrared LED 37 for sending infrared signal 52 to a printer 51 for printing a cardiac report 53.
  • Many standard printers are currently equipped with wireless sensors and respond to standard wireless protocols, such as IrDA (Infrared Data Association).
  • An optocoupler tranceiver incorporating an infrared LED and an optocoupler sensor, allows for bi-directional wireless communication of the patch with a reporting device.
  • a report can be sent to a wireless printer or wireless network using standard RF protocols such as Bluetooth® and IEEE802®.
  • RF radio frequency
  • a user or clinician can place the patch in proximity to a wireless reporting device for obtaining a cardiac report 53.
  • This report is generated internally by the processor 33 and sent wirelessly, either automatically when in proximity to a reporting device, or manually by activating a switch. For example by incorporating a reed-switch in the patch (not shown), which can be activated by a magnet placed in proximity to the patch when printing or reporting is desired.
  • the cardiac report in this preferred embodiment is automatically generated and formatted by the processor 33 of the invented patch.
  • Prior art reporting involves transmission of either raw ECG data or summary data for graphical formatting by a computer or microprocessor based device prior to sending to a printer or a display device.
  • the invented patch performs the analysis and formatting of results internally and sends directly to a generic printer or a generic Internet browser such as Microsoft® Internet Explorer, hi the later case, a capture screen is sent to the browser application by the invented patch. Once the capture screen is loaded, a report can then be printed or relayed to a medical monitoring station via the Internet.
  • the ability to generate a cardiac report wirelessly and directly to a generic reporting device simplifies the delivery of heart health care services. For example, an individual suspecting a cardiac abnormality, can purchase a disposable ECG patch and generate a report using standard printer available in most homes. A report can also be generated and broadcast to a wireless network. To ensue privacy, an access code can be provided with each patch for entering into the capture screen prior to viewing, printing, or forwarding to remote monitoring station. Similarly, non-cardiac medical practice, such as primary physician, family physician, nursing center, etc. can not perform a basic cardiac test and obtain a report without resorting to any specialized instruments or training.
  • ECG data can also be sent to a remote location via standard trans- telephonic methods (not shown) whereby a telephone line adapter device can be used to send translate ECG reports from the patch to the telephone line.
  • the adapter unit can communicate wirelessly to the patch via infrared or RS signals and subsequently dial the reporting center and transmit the cardiac report thereto.
  • An ECG report may also be retrieved by an interrogation device as shown in Fig. 9 (not to scale), hi this example, optical signal 19 representing ECG data from an infrared LED 37 incorporated within the disposable patch 10 is sent to an optical receiver 18 incorporated in the interrogation wand 16 of the external interrogation device 15.
  • the activation of the data transmission is preferably automatic.
  • a magnetic field 14 from a magnet 17 within the interface 16 triggers an activation sensor 41, i.e. a reed-switch, to initiate the ECG data transmission.
  • Activation can also be by manual means, such as by pressing an electromechanical switch (not shown) incorporated onto the flexible substrate 20.
  • the wireless transmission of cardiac data may be accomplished in numerous ways and methods known in the field of medical devices and wireless data transmission. This includes optical means as shown above, radio frequency (RF), magnetic, ultrasonic, and acoustic transmission. Inductive coupling through a coil (not shown) can also be used to transmit data, as well as for powering the patch externally during the transmission.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

La présente invention concerne un timbre à capteur jetable pour une surveillance non invasive et un enregistrement d'événements cardiaques peu fréquents. Le timbre est mince et souple afin d'être confortablement porté sur la poitrine d'une personne pour une analyse automatique et un enregistrement d'un ECG. Le timbre est bon marché et simple à s'autoadministrer. Le timbre contient une batterie, un amplificateur d'ECG et un processeur pour analyser la forme d'onde d'ECG et enregistrer des événements. Un algorithme logiciel recherche une anomalie cardiaque. Le timbre est conçu pour un port continu long dépassant 3 jours pour une surveillance diagnostique et dépassant 14 jours pour une détection d'événements. Dans un mode de réalisation, un rapport formaté au préalable est automatiquement généré par le timbre pour une transmission sans fil vers un dispositif de rapport tel qu'une imprimante générique ou un système en réseau sans fil. Le timbre peut également contenir un commutateur marqueur pour mettre en corrélation les données d'ECG enregistrées avec la perception du patient d'un événement cardiaque.
PCT/US2006/026249 2006-07-05 2006-07-05 timbre de surveillance cardiaque jetable à port prolongé Ceased WO2008005016A1 (fr)

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Application Number Priority Date Filing Date Title
PCT/US2006/026249 WO2008005016A1 (fr) 2006-07-05 2006-07-05 timbre de surveillance cardiaque jetable à port prolongé

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Application Number Priority Date Filing Date Title
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Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2465415A1 (fr) * 2010-12-20 2012-06-20 General Electric Company Capteurs biomédicaux à usage unique
US9226679B2 (en) 2010-05-21 2016-01-05 Medicomp, Inc. Systems and methods for interelectrode distance optimization in a retractable multi-use cardiac monitor
US9585584B2 (en) 2010-05-21 2017-03-07 Medicomp, Inc. Physiological signal monitor with retractable wires
US9955887B2 (en) 2014-10-31 2018-05-01 Irhythm Technologies, Inc. Wearable monitor
US10244986B2 (en) 2013-01-23 2019-04-02 Avery Dennison Corporation Wireless sensor patches and methods of manufacturing
US10271754B2 (en) 2013-01-24 2019-04-30 Irhythm Technologies, Inc. Physiological monitoring device
US10405799B2 (en) 2010-05-12 2019-09-10 Irhythm Technologies, Inc. Device features and design elements for long-term adhesion
EP3689227A4 (fr) * 2017-09-29 2021-06-16 Maxell Holdings, Ltd. Dispositif étanche à l'eau
US11083371B1 (en) 2020-02-12 2021-08-10 Irhythm Technologies, Inc. Methods and systems for processing data via an executable file on a monitor to reduce the dimensionality of the data and encrypting the data being transmitted over the wireless network
US11246523B1 (en) 2020-08-06 2022-02-15 Irhythm Technologies, Inc. Wearable device with conductive traces and insulator
US11350864B2 (en) 2020-08-06 2022-06-07 Irhythm Technologies, Inc. Adhesive physiological monitoring device
WO2022214850A1 (fr) * 2021-04-07 2022-10-13 Smartcardia Sa Système de surveillance d'un signe vital
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