[go: up one dir, main page]

WO2008081659A1 - 内視鏡システム - Google Patents

内視鏡システム Download PDF

Info

Publication number
WO2008081659A1
WO2008081659A1 PCT/JP2007/072725 JP2007072725W WO2008081659A1 WO 2008081659 A1 WO2008081659 A1 WO 2008081659A1 JP 2007072725 W JP2007072725 W JP 2007072725W WO 2008081659 A1 WO2008081659 A1 WO 2008081659A1
Authority
WO
WIPO (PCT)
Prior art keywords
fluorescence
information
unit
concentration
observation mode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2007/072725
Other languages
English (en)
French (fr)
Inventor
Masaya Nakaoka
Koki Morishita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olympus Corp
Original Assignee
Olympus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olympus Corp filed Critical Olympus Corp
Priority to US12/521,224 priority Critical patent/US8313426B2/en
Priority to EP07832450A priority patent/EP2098156A4/en
Priority to CN2007800480187A priority patent/CN101573068B/zh
Publication of WO2008081659A1 publication Critical patent/WO2008081659A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/05—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0655—Control therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/2823—Imaging spectrometer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406—Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Endoscopes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

　混合状態で取得された蛍光画像から各蛍光薬剤毎の蛍光の分布画像を取得することを可能とし、癌細胞の診断能を向上する。光学特性の異なる２種類以上の蛍光薬剤を励起させるために分光特性の異なる２種類以上の励起光を選択的に照射する光源部と、体腔内に入れられる部位に設けられ、各励起光により観察対象から放射される２種類以上の蛍光の波長帯域に受光感度を有する撮像部と、蛍光強度と各蛍光薬剤の濃度との相対関係情報を記憶する記憶部と、撮像部により撮影された２以上の画像の蛍光強度と記憶部に記憶されている相対関係情報とに基づいて、各蛍光薬剤の濃度情報を演算して出力する濃度情報演算部と、撮像部により取得された少なくとも１つの蛍光強度画像を提示する第１の蛍光観察モードと、濃度情報演算部により演算された各蛍光薬剤の濃度情報を提示する第２の蛍光観察モードとを切替可能なモード切替部とを備える内視鏡システムを提供する。
PCT/JP2007/072725 2006-12-28 2007-11-26 内視鏡システム Ceased WO2008081659A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/521,224 US8313426B2 (en) 2006-12-28 2007-11-26 Endoscope system
EP07832450A EP2098156A4 (en) 2006-12-28 2007-11-26 ENDOSCOPE SYSTEM
CN2007800480187A CN101573068B (zh) 2006-12-28 2007-11-26 内窥镜系统

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006356139A JP2008161550A (ja) 2006-12-28 2006-12-28 内視鏡システム
JP2006-356139 2006-12-28

Publications (1)

Publication Number Publication Date
WO2008081659A1 true WO2008081659A1 (ja) 2008-07-10

Family

ID=39588343

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/072725 Ceased WO2008081659A1 (ja) 2006-12-28 2007-11-26 内視鏡システム

Country Status (5)

Country Link
US (1) US8313426B2 (ja)
EP (1) EP2098156A4 (ja)
JP (1) JP2008161550A (ja)
CN (1) CN101573068B (ja)
WO (1) WO2008081659A1 (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102164530A (zh) * 2009-03-30 2011-08-24 奥林巴斯医疗株式会社 荧光观察装置
CN103654700A (zh) * 2013-12-31 2014-03-26 中国人民武装警察部队总医院 荧光内窥成像系统及成像方法
WO2019081833A1 (fr) * 2017-10-26 2019-05-02 Fluoptics Procédé et dispositif de suivi de la fluorescence émise à la surface d'un tissu biologique
CN111122855A (zh) * 2020-01-10 2020-05-08 上海泰辉生物科技有限公司 荧光免疫层析试纸条即时检测系统
CN115825032A (zh) * 2023-02-08 2023-03-21 之江实验室 一种数字化荧光仿生模体成像方法及系统

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8498695B2 (en) 2006-12-22 2013-07-30 Novadaq Technologies Inc. Imaging system with a single color image sensor for simultaneous fluorescence and color video endoscopy
BRPI0906187A2 (pt) 2008-03-18 2020-07-14 Novadaq Technologies Inc. método e sistema de representação de imagens para aquisição de imagens nir e imagens em cor total
JP5389380B2 (ja) 2008-05-28 2014-01-15 オリンパス株式会社 信号処理システム及び信号処理プログラム
ATE506000T1 (de) 2008-06-04 2011-05-15 Fujifilm Corp Beleuchtungsvorrichtung zur verwendung in endoskopen
JP5216429B2 (ja) * 2008-06-13 2013-06-19 富士フイルム株式会社 光源装置および内視鏡装置
JP4717103B2 (ja) * 2008-07-18 2011-07-06 オリンパス株式会社 信号処理システム及び信号処理プログラム
WO2011048887A1 (ja) 2009-10-20 2011-04-28 オリンパスメディカルシステムズ株式会社 蛍光観察装置
JP2011104199A (ja) * 2009-11-19 2011-06-02 Fujifilm Corp 内視鏡装置
JP5721959B2 (ja) * 2010-03-16 2015-05-20 オリンパス株式会社 蛍光内視鏡装置
JP5432793B2 (ja) * 2010-03-29 2014-03-05 オリンパス株式会社 蛍光内視鏡装置
US10682198B2 (en) 2010-07-02 2020-06-16 Intuitive Surgical Operations, Inc. Method and system for fluorescent imaging with background surgical image composed of selective illumination spectra
US9211058B2 (en) * 2010-07-02 2015-12-15 Intuitive Surgical Operations, Inc. Method and system for fluorescent imaging with background surgical image composed of selective illumination spectra
JP2012016545A (ja) * 2010-07-09 2012-01-26 Fujifilm Corp 内視鏡装置
CN103124514B (zh) * 2010-08-24 2016-09-28 欧司朗有限公司 具有荧光单元的颜色可调光源单元
JP5685406B2 (ja) * 2010-09-06 2015-03-18 富士フイルム株式会社 画像撮像装置およびその作動方法
JP5525991B2 (ja) * 2010-10-21 2014-06-18 富士フイルム株式会社 電子内視鏡システム、電子内視鏡システムのプロセッサ装置、及び電子内視鏡システムの作動方法
EP2596739A4 (en) * 2010-12-13 2017-08-16 Olympus Corporation Medical apparatus
JP5405445B2 (ja) 2010-12-17 2014-02-05 富士フイルム株式会社 内視鏡装置
JP5309120B2 (ja) 2010-12-20 2013-10-09 富士フイルム株式会社 内視鏡装置
CN103765091B (zh) 2011-03-08 2017-09-26 诺瓦达克技术公司 全光谱led照明器
WO2012124228A1 (ja) * 2011-03-15 2012-09-20 オリンパスメディカルシステムズ株式会社 医療装置
EP2599428B1 (en) * 2011-03-15 2017-09-06 Olympus Corporation Medical apparatus
JP2012217673A (ja) * 2011-04-11 2012-11-12 Fujifilm Corp 内視鏡診断装置
RU2641603C2 (ru) 2011-09-02 2018-01-18 Куэйкер Кемикал (Острелэйше) Пти Лтд Способ обнаружения проникновения текучей среды в пациента
EP2793697A4 (en) * 2011-12-21 2015-08-19 Catherine M Shachaf SYSTEM FOR THE IMPROVEMENT OF TISSUE ELEMENTS
DE102011122602A1 (de) * 2011-12-30 2013-07-04 Karl Storz Gmbh & Co. Kg Vorrichtung und Verfahren zur endoskopischen Fluoreszenzdetektion
US11433147B2 (en) 2014-02-10 2022-09-06 Quaker Chemical (Australasia) Pty Ltd Fluorescent fluid for detecting fluid injection
JP2014161500A (ja) * 2013-02-25 2014-09-08 Canon Inc 画像処理装置、眼科撮影装置及び方法、並びにプログラム
CN104780825B (zh) * 2013-05-29 2016-09-21 奥林巴斯株式会社 内窥镜系统
EP2976989A4 (en) * 2013-07-11 2017-03-15 Olympus Corporation Light source device
JP6062076B2 (ja) * 2014-09-19 2017-01-18 オリンパス株式会社 ユニット、モジュールとコネクタとの接続方法、および内視鏡システム
CN107405053B (zh) * 2015-10-22 2019-08-02 奥林巴斯株式会社 内窥镜系统
EP4442222A3 (en) 2015-11-13 2024-12-18 Stryker Corporation Systems and methods for illumination and imaging of a target
EP3408654B1 (en) 2016-01-26 2022-08-03 Stryker European Operations Limited Fluorescence imaging system and method for fluorescence imaging
USD916294S1 (en) 2016-04-28 2021-04-13 Stryker European Operations Limited Illumination and imaging device
EP3469420A4 (en) 2016-06-14 2020-02-12 Novadaq Technologies ULC ADAPTIVE IMAGING METHODS AND SYSTEMS FOR IMPROVING LOW LIGHT SIGNALS IN MEDICAL VISUALIZATION
CN109475270B (zh) * 2016-11-01 2021-04-27 奥林巴斯株式会社 活体观察系统
EP3580609B1 (en) 2017-02-10 2023-05-24 Stryker European Operations Limited Open-field handheld fluorescence imaging systems and methods
WO2019123796A1 (ja) * 2017-12-22 2019-06-27 オリンパス株式会社 内視鏡システム
EP3731728B1 (en) * 2017-12-27 2024-09-25 Ethicon LLC Hyperspectral imaging with tool tracking in a light deficient environment
JP7549532B2 (ja) * 2018-08-17 2024-09-11 富士フイルム株式会社 内視鏡システム
US12268469B2 (en) * 2018-11-30 2025-04-08 Intuitive Surgical Operations, Inc. Medical imaging systems and methods that facilitate use of different fluorescence imaging agents

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09308604A (ja) * 1996-03-06 1997-12-02 Fuji Photo Film Co Ltd 蛍光検出装置
JPH10201707A (ja) 1996-11-20 1998-08-04 Olympus Optical Co Ltd 内視鏡装置
JP2001137173A (ja) * 1999-11-11 2001-05-22 Fuji Photo Film Co Ltd 蛍光画像測定方法および装置
JP2006025802A (ja) * 2003-06-17 2006-02-02 Olympus Corp 内視鏡装置
JP2006187598A (ja) * 2004-12-08 2006-07-20 Olympus Corp 蛍光内視鏡装置及びそれに用いる撮像ユニット

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5749830A (en) * 1993-12-03 1998-05-12 Olympus Optical Co., Ltd. Fluorescent endoscope apparatus
JP5088990B2 (ja) * 1999-01-26 2012-12-05 Ｈｏｙａ株式会社 内視鏡用の自己蛍光画像化システム
EP1301118B1 (en) * 2000-07-14 2006-09-06 Xillix Technologies Corp. Compact fluorescence endoscopy video system
US6582363B2 (en) * 2000-08-25 2003-06-24 Pentax Corporation Video endoscope system and illumination optical system
US7172553B2 (en) * 2001-05-16 2007-02-06 Olympus Corporation Endoscope system using normal light and fluorescence
US20050027166A1 (en) 2003-06-17 2005-02-03 Shinya Matsumoto Endoscope system for fluorescent observation
JP4575720B2 (ja) * 2004-07-23 2010-11-04 Ｈｏｙａ株式会社 電子内視鏡システム
JP5197916B2 (ja) * 2004-09-08 2013-05-15 オリンパス株式会社 内視鏡装置
JP4555093B2 (ja) * 2005-01-05 2010-09-29 Ｈｏｙａ株式会社 電子内視鏡システム
US20060173358A1 (en) * 2005-01-11 2006-08-03 Olympus Corporation Fluorescence observation endoscope apparatus and fluorescence observation method
JP5114024B2 (ja) * 2005-08-31 2013-01-09 オリンパス株式会社 光イメージング装置
JP4761899B2 (ja) * 2005-09-12 2011-08-31 Ｈｏｙａ株式会社 電子内視鏡システム

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09308604A (ja) * 1996-03-06 1997-12-02 Fuji Photo Film Co Ltd 蛍光検出装置
JPH10201707A (ja) 1996-11-20 1998-08-04 Olympus Optical Co Ltd 内視鏡装置
JP2001137173A (ja) * 1999-11-11 2001-05-22 Fuji Photo Film Co Ltd 蛍光画像測定方法および装置
JP2006025802A (ja) * 2003-06-17 2006-02-02 Olympus Corp 内視鏡装置
JP2006187598A (ja) * 2004-12-08 2006-07-20 Olympus Corp 蛍光内視鏡装置及びそれに用いる撮像ユニット

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2098156A4

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102164530A (zh) * 2009-03-30 2011-08-24 奥林巴斯医疗株式会社 荧光观察装置
EP2322075A4 (en) * 2009-03-30 2011-10-26 Olympus Medical Systems Corp FLUORESCENCE OBSERVATION DEVICE
CN102164530B (zh) * 2009-03-30 2014-07-30 奥林巴斯医疗株式会社 荧光观察装置
CN103654700A (zh) * 2013-12-31 2014-03-26 中国人民武装警察部队总医院 荧光内窥成像系统及成像方法
CN103654700B (zh) * 2013-12-31 2016-08-31 中国人民武装警察部队总医院 荧光内窥成像系统及成像方法
WO2019081833A1 (fr) * 2017-10-26 2019-05-02 Fluoptics Procédé et dispositif de suivi de la fluorescence émise à la surface d'un tissu biologique
US12453475B2 (en) 2017-10-26 2025-10-28 Fluoptics Method and device for monitoring fluorescence diffusion images emitted at the surface of a biological tissue and automatically determining the variations between fluorescence images
CN111122855A (zh) * 2020-01-10 2020-05-08 上海泰辉生物科技有限公司 荧光免疫层析试纸条即时检测系统
CN111122855B (zh) * 2020-01-10 2023-04-11 上海泰辉生物科技有限公司 荧光免疫层析试纸条即时检测系统
CN115825032A (zh) * 2023-02-08 2023-03-21 之江实验室 一种数字化荧光仿生模体成像方法及系统
US12109073B2 (en) 2023-02-08 2024-10-08 Zhejiang Lab Meta fluorescence tissue mimicking phantom of imaging method and system

Also Published As

Publication number Publication date
CN101573068B (zh) 2011-01-26
US20100094136A1 (en) 2010-04-15
EP2098156A4 (en) 2011-05-11
EP2098156A1 (en) 2009-09-09
JP2008161550A (ja) 2008-07-17
US8313426B2 (en) 2012-11-20
CN101573068A (zh) 2009-11-04

Similar Documents

Publication Publication Date Title
WO2008081659A1 (ja) 内視鏡システム
US8214025B2 (en) Fluorescence endoscope system
EP2105082B1 (en) Fluorescence observing device and fluorescence observing method
US8188446B2 (en) Fluorescence imaging apparatus
EP2322075B1 (en) Fluorescence observation device
CN101646379B (zh) 活体组织用荧光观察装置
EP2468186B1 (en) Endoscopic diagnosis system
US8306600B2 (en) Filter set for observing fluorescence radiation in biological tissue
US20100268091A1 (en) Fluorescence imaging apparatus and endoscope apparatus
US20120184812A1 (en) Endoscope system
US20110012025A1 (en) Fluorescence observation apparatus
US20110172492A1 (en) Medical apparatus and endoscope apparatus
WO2008093746A1 (ja) 蛍光観察装置および蛍光観察方法
US20180252909A1 (en) Microscopy system and microscopy method for quantifying a fluorescence
JP5220961B2 (ja) 生体内観察装置およびカプセル型内視鏡装置
US8105232B2 (en) Fluorescent endoscopic device and method of creating fluorescent endoscopic image
EP2952132A1 (en) Light source device, subject observation device and light source control method
US20190059712A1 (en) Endoscope light source apparatus
EP2520212A1 (en) Fluorescence endoscope device
CN106455931B (zh) 内窥镜
US20100194871A1 (en) Fluorescence endoscope system and fluorescence imaging method
US20130053703A1 (en) Endoscopic diagnosis system
US20100036203A1 (en) Endoscope system
KR101180384B1 (ko) 생체 내 ｕｃｎｐ 광학 이미징용 이중 영상장치
CN105939651A (zh) 医疗用图像形成装置

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200780048018.7

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07832450

Country of ref document: EP

Kind code of ref document: A1

REEP Request for entry into the european phase

Ref document number: 2007832450

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2007832450

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 12521224

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE