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WO2008057003A1 - Composition de soin pour les ongles - Google Patents

Composition de soin pour les ongles Download PDF

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Publication number
WO2008057003A1
WO2008057003A1 PCT/RU2006/000585 RU2006000585W WO2008057003A1 WO 2008057003 A1 WO2008057003 A1 WO 2008057003A1 RU 2006000585 W RU2006000585 W RU 2006000585W WO 2008057003 A1 WO2008057003 A1 WO 2008057003A1
Authority
WO
WIPO (PCT)
Prior art keywords
composition
nail
water
nail care
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/RU2006/000585
Other languages
English (en)
Inventor
Tatyana Vyacheslavovna Popkova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to PCT/RU2006/000585 priority Critical patent/WO2008057003A1/fr
Publication of WO2008057003A1 publication Critical patent/WO2008057003A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q3/00—Manicure or pedicure preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/362—Polycarboxylic acids

Definitions

  • the present invention provides a nail care composition. More particularly, the invention provides aqueous alcohol-free compositions comprising succinic acid or salts thereof, which compositions are useful for improving nail health and appearance.
  • Nails are often subjected to a wide variety of conditions that can cause damage. These include exposure of nails to chemicals such as nail polish removers (e.g. acetone), detergents, and alkaline conditions; the use of glues and adhesives for the attachment of plastic artificial nails over the true natural nail; traumas; and stresses. Moreover, nail health can be affected with aging. Thus, there is the great need in accelerating nail growth and regeneration, and improving nail health and appearance.
  • nail polish removers e.g. acetone
  • detergents e.g. acetone
  • nail care compositions contain alcohols.
  • Alcohols having about 2-8 carbon atoms e.g. ethanol, butanol, or isopropanol
  • solvents are typically used to solubilize components of compositions and enhance absorption of active components of compositions through a skin barrier.
  • alcohols are irritants for skin and nails.
  • alcohol is toxic for skin cells and consequently may be harmful to the skin and nails after repeated use.
  • 957905 in Bulletin of Inventions, Discoveries, Industrial Prototypes, and Trade Marks [in Russian], No. 34, 1982) teaches an alcohol containing herbal lotion for nail care, the lotion contains 5 to 10% w/w extract of hops, 5 to 10% w/w extract of coltsfoot, 30-40% w/w polyethyleneglycol-40, 0.1 to 0.2% w/w fragrances, 0.1 to 0.2% w/w succinic acid, and ethyl alcohol/water up to 100% w/w.
  • U.S.S.R. Pat. No. 957905 teaches that the goal to use of this composition is to prevent a nail splitting and fragility arising from the use of a previously known lotion for nails comprising alcohol, water, and fragrance.
  • the herbal extracts of the lotion are multicomponent compositions of biologically active organic substances. Extract of coltsfoot (Tussilago farfara) contains substances: mucilage, inulin, tannins, flavonoids, triterpenes, pyrrolizidine alkaloids, bitter glycosides, choline, phytosterols, and tussilagone (sesquiterpene).
  • Extract of hops contains substances: more of 150 aroma substances; tannins; flavonoids including kaempferol and quercetin mono- and diglycosides; xanthohumol and other chalcones; phenol-carboxylic acids (ferulic and chlorogenic acids); phytoestrogen flavonoids including 8-prenylnaringenin, and structurally related hop flavonoids, 6-prenylnaringenin, 6,8-diprenylnaringenin and 8-geranylnaringenin. Accordingly U.S.S.R. Pat. No. 957905, the effect of the lotion is achieved as a total effect of all active substances which are included in the lotion, whereas the effect of each substance is unknown.
  • aqueous compositions are not effective for topical use in the absence of promoters of absorption (e.g. alcohols) because of barrier function of skin and nail.
  • promoters of absorption e.g. alcohols
  • alcohol-free aqueous composition of succinic acid is effective for improvement of nail health and appearance. Accordingly, it is an object of the invention to provide an aqueous alcohol-free nail care composition comprising an effective amount of succinic acid or salt thereof.
  • the present invention provides an aqueous alcohol-free nail care composition comprising an effective amount of succinic acid or salt thereof.
  • nail means fingernail or toenail.
  • aqueous means that water is used as a major carrier or diluent in compositions of the invention.
  • Nonexclusive examples of water suitable for the use in the compositions of the invention are distilled water, deionized water, pharmaceutical water, water with content of heavy water isotopes distinct of the natural such as deuterium depleted water, oxygen- 17 depleted water, and oxygen- 18 depleted water.
  • alcohol-free means that compositions of the inventions do not contains alcohols having about 2-8 carbon atoms, e.g. ethanol, butanol, or isopropanol.
  • nail care composition refers to any composition which comprises one or more agents which, when transferred from an article to a nail or skin surrounding the nail, provide a nail benefit. Representative materials are discussed in detail below.
  • the salts of succinic acid suitable for use herein are those salts prepared by the reaction of succinic acid with safe and non-toxic organic or inorganic base.
  • examples of such bases include, but are not limited to, sodium hydroxide, potassium hydroxide, ammonium hydroxide, monoethanolamine, diethanolamine and triethanolamine.
  • the effective amount of succinic acid or salts thereof is from about 0.21 to about 10 % by weight.
  • the composition has a pH from about 3.8 to about 7.5.
  • the composition of the present invention is a solution.
  • composition of the present invention is a spray.
  • composition of the present invention is an emulsion.
  • the composition of the present invention is a gel.
  • the composition of the present invention additionally comprising from about 0.01 to 10% by weight a gelling agent, preferably from about 0.2% to about 5.0% by weight.
  • Nonexclusive examples of suitable gelling agents include crosslinked carboxylic acid polymers; unneutralized crosslinked carboxylic acid polymers; unneutralized modified crosslinked carboxylic acid polymers; unneutralized crosslinked allyl ether/acrylate copolymers (e.g., Salcare SC90 commercially available from Allied Colloids); crosslinked ethylene/maleic anhydride copolymers; unneutralized crosslinked ethylene/maleic anhydride copolymers (e.g., EMA 81 commercially available from Monsanto); unneutralized crosslinked copolymers of sodium polyacrylate, mineral oil, and PEG-I trideceth-6 (e.g., Salcare SC91 commercially available from Allied Colloids); unneutralized crosslinked copolymers of methyl vinyl ether and maleic anhydride (e.g., Stabileze QM-PVM/MA copolymer commercially available from International Specialty Products); hydrophobically modified nonionic cellulose polymers; hydrophobically modified e
  • Preferred gelling agents include water-soluble unneutralized crosslinked ethylene/maleic anhydride copolymers, water-soluble unneutralized crosslinked carboxylic acid polymers, and water-soluble hydrophobically modified nonionic cellulose polymers.
  • the crosslinked carboxylic acid polymers and hydrophobically modified nonionic cellulose polymers are described in detail hereinbelow.
  • the carboxylic acid polymers suitable for use herein are those crosslinked compounds containing one or more monomers derived from acrylic acid, substituted acrylic acids, esters of acrylic acid, esters of substituted acrylic acids, corresponding salts thereof, and combinations thereof, wherein the crosslinking agent contains two or more carbon-carbon double bonds and is derived from a polyhydric alcohol.
  • carboxylic acid polymers include crosslinked carboxylic acid homopolymers and crosslinked carboxylic acid copolymers. Combinations of these two types of polymers are also useful herein.
  • carboxylic acid polymers include, but are not limited to, acrylic acid/ethyl aery late copolymers and the carboxy vinyl polymers sold by the B. F. Goodrich Company under the trade mark of Carbopol resins such as Carbopol 934, Carbopol 940, Carbopol 950, Carbopol 954, Carbopol 980, Carbopol 951 and Carbopol 981.
  • Neutralizing agents suitable for use in neutralizing acidic group containing hydrophilic gelling agents herein include sodium hydroxide, potassium hydroxide, ammonium hydroxide, monoethanolamine, diethanolamine and triethanolamine.
  • the hydrophobically modified nonionic cellulose polymers suitable for use herein are those compounds which have been modified to comprise substituted hydrophobic groups to make the polymer less soluble in water.
  • the nonionic cellulose polymers comprise a water-soluble cellulosic chain (or hydrophilic cellulosic chain) which forms the backbone, wherein the backbone comprise substituted hydrophobic groups.
  • Suitable cellulose ether substrates include any known or otherwise effective water-soluble nonionic cellulose ether.
  • Nonlimiting examples of suitable water-soluble nonionic cellulose ethers include, but are not limited to, hydroxyethyl cellulose, hydroxypropyl cellulose, methyl cellulose, hydroxypropyl methyl cellulose, ethyl hydroxyethyl cellulose, and methyl hydroxyethyl cellulose.
  • the amount of the nonionic substituent e.g., methyl, hydroxyethyl, or hydroxypropyl substituent
  • Optional materials suitable for use in the aqueous alcohol-free nail care composition of the present invention include, but are not limited to, preservatives, surfactants, conditioning polymers, electrolytes, pH adjusting agents, perfume oils, perfume solubilizing agents, protein derivatives, and colouring agents.
  • concentration of such optional ingredients generally ranges from zero to about 25%, more typically from about 0.05% to about 25%, even more typically from about 0.1% to about 15%, by weight of the composition.
  • compositions of the invention are prepared by methods well-known from the art. Such methods include, but are not limited to, mixing the ingredients of the composition and packaging resulted mixtures to suitable packages, e.g. tubes.
  • the present invention provides a method for nail care, which method comprises a step of applying an effective amount of the composition of the invention to the nail and skin surrounding the nail.
  • an effective amount of the composition of the invention for example, 0.5 g of the composition of the invention is applied onto nail plate (e.g. fingernail or toenail) and skin surrounding the nail plate for one time per day or several times per day.
  • the composition may be applied for one day or longer, preferably for 30 days.
  • the term "effective amount” means an amount sufficient to provide the desired effect on nail health and appearance.
  • compositions and methods of the present invention it is possible to improve nail health and appearance, accelerate nail growth and regeneration, to make nails more strength and flexible, and eliminate nail problems such as changes in the shape and texture of nails, thickened nails, nail fragility, and brittle nails.
  • This example shows a representative gel for nail care.
  • the method for preparing the gel was as follows: the succinic acid, water, carboxyethylcellulose and other components were mixed.
  • This example shows a representative solution for nail care. Content, % w/w
  • the method for preparing the solution was as follows: the succinic acid, water, and other components were mixed.
  • This example shows a representative emulsion for nail care.
  • the method for preparing the emulsion was as follows: the succinic acid, almond oil, water, and other components were mixed.
  • This example shows a representative spray for nail care.
  • the method for preparing the spray was as follows: the succinic acid, water, carboxyethylcellulose and other components were mixed.
  • This example demonstrates the method for nail care.
  • Gel of the example 1 of the invention was used.
  • the 0.5 g of the gel is applied onto fingernail nail plate and skin surrounding the nail plate one time per day for 4 weeks.
  • the use of the gel of the invention improved nail health and appearance.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

Cette invention concerne une composition aqueuse sans alcool destinée au soin des ongles et comprenant une quantité efficace d'acide succinique ou de l'un de ses sels. L'invention concerne également le procédé de soin des ongles, ledit procédé comprenant l'étape consistant à appliquer une quantité efficace des compositions de l'invention sur les ongles et sur la peau qui entoure les ongles.
PCT/RU2006/000585 2006-11-08 2006-11-08 Composition de soin pour les ongles Ceased WO2008057003A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/RU2006/000585 WO2008057003A1 (fr) 2006-11-08 2006-11-08 Composition de soin pour les ongles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU2006/000585 WO2008057003A1 (fr) 2006-11-08 2006-11-08 Composition de soin pour les ongles

Publications (1)

Publication Number Publication Date
WO2008057003A1 true WO2008057003A1 (fr) 2008-05-15

Family

ID=38476971

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2006/000585 Ceased WO2008057003A1 (fr) 2006-11-08 2006-11-08 Composition de soin pour les ongles

Country Status (1)

Country Link
WO (1) WO2008057003A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3206350A1 (de) * 1981-02-23 1982-09-23 Kao Soap Co., Ltd., Tokyo Fluessige reinigungsmittelmischung
WO1994010971A1 (fr) * 1992-11-11 1994-05-26 Unilever Plc Composition cosmetique renfermant des esters d'acide succinique
WO2001028339A2 (fr) * 1999-10-19 2001-04-26 The Procter & Gamble Company Composition antimicrobienne comprenant un acide organique biologiquement actif
EP1262166A1 (fr) * 2001-06-01 2002-12-04 Cognis France S.A. Compositions cosmétiques et/ou pharmaceutiques contenant un extrait de Pterocarpus marsupium

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3206350A1 (de) * 1981-02-23 1982-09-23 Kao Soap Co., Ltd., Tokyo Fluessige reinigungsmittelmischung
WO1994010971A1 (fr) * 1992-11-11 1994-05-26 Unilever Plc Composition cosmetique renfermant des esters d'acide succinique
WO2001028339A2 (fr) * 1999-10-19 2001-04-26 The Procter & Gamble Company Composition antimicrobienne comprenant un acide organique biologiquement actif
EP1262166A1 (fr) * 2001-06-01 2002-12-04 Cognis France S.A. Compositions cosmétiques et/ou pharmaceutiques contenant un extrait de Pterocarpus marsupium

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