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WO2008055630A1 - Implant dentaire doté d'un revêtement - Google Patents

Implant dentaire doté d'un revêtement Download PDF

Info

Publication number
WO2008055630A1
WO2008055630A1 PCT/EP2007/009549 EP2007009549W WO2008055630A1 WO 2008055630 A1 WO2008055630 A1 WO 2008055630A1 EP 2007009549 W EP2007009549 W EP 2007009549W WO 2008055630 A1 WO2008055630 A1 WO 2008055630A1
Authority
WO
WIPO (PCT)
Prior art keywords
implant according
implant
plastic
microns
depressions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2007/009549
Other languages
German (de)
English (en)
Inventor
Dirk-Rolf Gieselmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CLINICAL HOUSE EUROPE GmbH
Original Assignee
CLINICAL HOUSE EUROPE GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CLINICAL HOUSE EUROPE GmbH filed Critical CLINICAL HOUSE EUROPE GmbH
Publication of WO2008055630A1 publication Critical patent/WO2008055630A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A61C8/0016—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy polymeric material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses

Definitions

  • the invention relates to an implant for anchoring dentures, in particular crowns, with an endosseous portion and a gingival portion, wherein the implant is equipped with a biocompatible plastic.
  • dental implants are often used today, which represent an anchoring option for dentures, such as crowns, bridges or full dentures.
  • Dental implants are in this sense anchored in the jawbone pillars, which have the function of an artificial tooth root. These are fixed posts that are inserted (implanted) in the corresponding jawbone. They enable the insertion of individual teeth as well as bridges, without having to process healthy neighboring teeth.
  • the implant usually consists of several parts, namely a base body, which represents the actual anchorage, a post which is fitted into the base body and receives the crown or bridge or prosthesis, and a fastening means, with which the post on the base body is anchored, if the construction of such an aid is required.
  • Implants have an endosseous and a gingival part.
  • the enossal part is located in the jawbone.
  • the gingival part protrudes from the jaw bone out into the gums or gingiva. While the endosseous part is subject to osseointegration, connective tissue and epithelial tissue attach to the gingival part.
  • the main body of an implant is usually completely in the jawbone, but can protrude into the gingiva with its upper, open end.
  • the post usually comes into contact only with the gingiva.
  • Dental implants are often made of titanium. Titanium and bone tissue are well tolerated so osseointegration usually progresses quickly and easily.
  • the object of the invention is to provide an implant which is suitable for promoting the healing process and counteracting como plications of the type described above.
  • biocompatible plastics are basically known from WO 00/015273 A.
  • a coating without the addition of other active pharmaceutical ingredients has an osteosynthetic and an anti-infective and thus avoiding complications.
  • a lacquer-like formation of the coating should be avoided that it is abraded during application of the implant by mechanical action or otherwise damaged.
  • the depressions are in the form of lacunae-like pores, for example with a size of 0.1 to 10 ⁇ m and in particular 0.5 to 2.5 ⁇ m.
  • Such pores can be produced for example by spark erosion or chemical etching. Very useful has been a method called anodizing under spark discharge (ANOF).
  • ANOF anodizing under spark discharge
  • the depressions in the implants according to the invention can also be produced by drilling, milling or cutting, for example in the form of elongated recesses or grooves, which for example have a length of 1 to 500 ⁇ m, in particular 5 to 150 ⁇ m, at a width and depth of 0, 1 to 10 microns, in particular 0.5 to 5 microns have.
  • milled depressions of up to 50 ⁇ m in length and up to 5 ⁇ m in width and depth are suitable.
  • Such depressions can be generated by means of CNC methods.
  • Dotted or elongated depressions formed by laser ablation are also contemplated, for example, notches or grooves that are perpendicular to or with the screw thread.
  • notches or grooves that are perpendicular to or with the screw thread.
  • milled or cut recesses it should be noted that they are not dimensioned too large in order to protect plastic materials incorporated therein from the forces that occur when anchoring the implants in the jawbone.
  • lacunae-like depressions which can be produced by means of anodic oxidation with spark discharge (ANOF process).
  • the depressions are expediently distributed uniformly over the entire surface of the implant, as far as this comes into contact with body tissue, but at least in the enossal region of the implant.
  • these are preferably arranged in the longitudinal direction, d. H. substantially perpendicular to the course of the screw thread, with which the implant is screwed into the jawbone.
  • corresponding grooves can also be provided within the turns of the screw thread, for example in the form of running with the thread elongated cuts, grooves or notches.
  • the biocompatible plastic used in the implants according to the invention can be any plastic that is approved for this purpose and in particular biodegradable.
  • the plastics mentioned in WO 00/015273 A are suitable, for example. Preference is given to poly-alpha-hydroxycarboxylic acids and polyglycols, and including polylactides, polyglycolic acids and copolymers thereof.
  • the biocompatible plastic can be distributed as a uniform layer over the entire surface, but is particularly and preferably exclusively in the inventively provided wells. If the plastic is applied as a uniform layer, the layer thickness is generally less than 20 microns and is for example in the range of 5 to 10 microns.
  • the biocompatible plastic may include a medicinal agent, particularly one that promotes the healing of the implant into the bone tissue and / or gingival tissue.
  • a medicinal agent particularly one that promotes the healing of the implant into the bone tissue and / or gingival tissue.
  • This may, for example, a Antibiotic act, which counteracts inflammatory phenomena, especially those inflammations, as they occur in the gingiva.
  • active substances which promote osteosynthesis and thus ingrowth, for example growth factors such as IGF 5 or TGF.
  • IGF 5 or TGF growth factors
  • the active ingredient content is generally 0.1 to 10 wt .-%, preferably up to 5 wt .-%, based on the mass of the biocompatible plastic.
  • the biocompatible plastic can be applied to the implant in the usual way and introduced into the wells, for example by spraying, dipping or any other treatment which leads to the desired result.
  • the flat projection can be removed by mechanical processing, for example by means of brushes, blasting, drums or the like. The removal procedure must ensure that the plastic entry in the recesses is maintained.
  • the biocompatible plastic doped with the active substance which is located in the depressions of the implant, is not further affected by the screwing in.
  • the biocompatible plastic doped with the active substance which is located in the depressions of the implant
  • the healing phase can be shortened in this way and the implant can be loaded earlier by the patient.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ceramic Engineering (AREA)
  • Dentistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dental Prosthetics (AREA)

Abstract

L'invention concerne un implant servant à ancrer une prothèse dentaire, en particulier des couronnes, comprenant une section endo-osseuse et une section gingivale, ainsi que plusieurs cavités formées au moins dans la section endo-osseuse et dans lesquelles est introduite une matière synthétique biocompatible.
PCT/EP2007/009549 2006-11-06 2007-11-05 Implant dentaire doté d'un revêtement Ceased WO2008055630A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200610052552 DE102006052552A1 (de) 2006-11-06 2006-11-06 Beschichtetes Zahnimplantat
DE102006052552.3 2006-11-06

Publications (1)

Publication Number Publication Date
WO2008055630A1 true WO2008055630A1 (fr) 2008-05-15

Family

ID=39154247

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/009549 Ceased WO2008055630A1 (fr) 2006-11-06 2007-11-05 Implant dentaire doté d'un revêtement

Country Status (2)

Country Link
DE (1) DE102006052552A1 (fr)
WO (1) WO2008055630A1 (fr)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996016611A1 (fr) * 1994-11-30 1996-06-06 Implant Innovations, Inc. Preparation d'une surface d'implant
US5766009A (en) * 1995-01-20 1998-06-16 Jeffcoat; Robert L. Elastically stabilized endosseous dental implant
US5947893A (en) * 1994-04-27 1999-09-07 Board Of Regents, The University Of Texas System Method of making a porous prothesis with biodegradable coatings
WO2000015273A1 (fr) 1998-09-11 2000-03-23 Gerhard Schmidmaier Implants a action biologique
WO2000072777A1 (fr) * 1999-05-31 2000-12-07 Nobel Biocare Ab (Publ) Implant, son procede de production et son utilisation
WO2002069817A1 (fr) * 2001-03-02 2002-09-12 Woodwelding Ag Implants, dispositif et procede permettant de relier des parties de tissu
WO2004017857A1 (fr) * 2002-08-23 2004-03-04 Woodwelding Ag Implant a implanter dans un tissu osseux ou dans un tissu osseux comble par un materiau de substitution osseuse
EP1529497A1 (fr) * 2003-11-04 2005-05-11 Friadent GmbH Composant Implant Dentaire
WO2006089380A1 (fr) * 2005-02-24 2006-08-31 Roland Dricot Implant osseux
WO2007074968A1 (fr) * 2005-12-26 2007-07-05 Cowellmedi Co., Ltd. Implant dentaire revêtu d'une protéine morphogénique osseuse recombinée et procédé de revêtement de celui-ci

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5947893A (en) * 1994-04-27 1999-09-07 Board Of Regents, The University Of Texas System Method of making a porous prothesis with biodegradable coatings
WO1996016611A1 (fr) * 1994-11-30 1996-06-06 Implant Innovations, Inc. Preparation d'une surface d'implant
US5766009A (en) * 1995-01-20 1998-06-16 Jeffcoat; Robert L. Elastically stabilized endosseous dental implant
WO2000015273A1 (fr) 1998-09-11 2000-03-23 Gerhard Schmidmaier Implants a action biologique
WO2000072777A1 (fr) * 1999-05-31 2000-12-07 Nobel Biocare Ab (Publ) Implant, son procede de production et son utilisation
WO2002069817A1 (fr) * 2001-03-02 2002-09-12 Woodwelding Ag Implants, dispositif et procede permettant de relier des parties de tissu
WO2004017857A1 (fr) * 2002-08-23 2004-03-04 Woodwelding Ag Implant a implanter dans un tissu osseux ou dans un tissu osseux comble par un materiau de substitution osseuse
EP1529497A1 (fr) * 2003-11-04 2005-05-11 Friadent GmbH Composant Implant Dentaire
WO2006089380A1 (fr) * 2005-02-24 2006-08-31 Roland Dricot Implant osseux
WO2007074968A1 (fr) * 2005-12-26 2007-07-05 Cowellmedi Co., Ltd. Implant dentaire revêtu d'une protéine morphogénique osseuse recombinée et procédé de revêtement de celui-ci

Also Published As

Publication number Publication date
DE102006052552A1 (de) 2008-05-08

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