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WO2006099914A8 - Verfahren zur herstellung von naringeninderivaten aus xanthohumol - Google Patents

Verfahren zur herstellung von naringeninderivaten aus xanthohumol

Info

Publication number
WO2006099914A8
WO2006099914A8 PCT/EP2006/001061 EP2006001061W WO2006099914A8 WO 2006099914 A8 WO2006099914 A8 WO 2006099914A8 EP 2006001061 W EP2006001061 W EP 2006001061W WO 2006099914 A8 WO2006099914 A8 WO 2006099914A8
Authority
WO
WIPO (PCT)
Prior art keywords
xanthohumol
derivatives
naringenin derivatives
producing
producing naringenin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2006/001061
Other languages
English (en)
French (fr)
Other versions
WO2006099914A1 (de
Inventor
Heike Wilhelm
Ludger A Wessjohann
Martin Biendl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HOPSTEINER-HALLERTAUER HOPFENVEREDELUNGSGESELLSCHAFT MBH
HOPSTEINER HALLERTAUER HOPFENV
Original Assignee
HOPSTEINER-HALLERTAUER HOPFENVEREDELUNGSGESELLSCHAFT MBH
HOPSTEINER HALLERTAUER HOPFENV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HOPSTEINER-HALLERTAUER HOPFENVEREDELUNGSGESELLSCHAFT MBH, HOPSTEINER HALLERTAUER HOPFENV filed Critical HOPSTEINER-HALLERTAUER HOPFENVEREDELUNGSGESELLSCHAFT MBH
Priority to US11/908,427 priority Critical patent/US8067622B2/en
Priority to JP2008502261A priority patent/JP2008538208A/ja
Publication of WO2006099914A1 publication Critical patent/WO2006099914A1/de
Anticipated expiration legal-status Critical
Publication of WO2006099914A8 publication Critical patent/WO2006099914A8/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/32—2,3-Dihydro derivatives, e.g. flavanones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Die vorliegende Erfindung betrifft ein effizientes Verfahren zur Herstellung von Naringeninderivaten aus Xanthohumol bzw. dessen Derivaten. Insbesondere umfasst das Verfahren gemäß der vorliegenden Erfindung die Herstellung von Isoxanthohumol, beispielsweise auch in enantiomerenangereicherter Form, aus Xanthohumol und anschließende Demethylierung von Isoxanthohumol gemäß spezifischen Vorgehensweisen unter Erhalten von entsprechenden Naringeninderivaten, wie insbesondere 8-Prenylnaringenin.
PCT/EP2006/001061 2005-03-22 2006-02-07 Verfahren zur herstellung von naringeninderivaten aus xanthohumol Ceased WO2006099914A1 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US11/908,427 US8067622B2 (en) 2005-03-22 2006-02-07 Method for producing naringenin derivatives from xanthohumol
JP2008502261A JP2008538208A (ja) 2005-03-22 2006-02-07 キサントフモールからナリンゲニン誘導体を製造する方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005013258A DE102005013258B3 (de) 2005-03-22 2005-03-22 Verfahren zur Herstellung von Naringeninderivaten aus Xanthohumol
DE102005013258.8 2005-03-22

Publications (2)

Publication Number Publication Date
WO2006099914A1 WO2006099914A1 (de) 2006-09-28
WO2006099914A8 true WO2006099914A8 (de) 2008-04-03

Family

ID=36169171

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/001061 Ceased WO2006099914A1 (de) 2005-03-22 2006-02-07 Verfahren zur herstellung von naringeninderivaten aus xanthohumol

Country Status (4)

Country Link
US (1) US8067622B2 (de)
JP (1) JP2008538208A (de)
DE (1) DE102005013258B3 (de)
WO (1) WO2006099914A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100465185C (zh) * 2006-12-01 2009-03-04 华东理工大学 一种制备异日本獐牙菜素的方法
CZ307451B6 (cs) * 2014-12-16 2018-09-05 Vysoká škola chemicko-technologická v Praze Způsob přípravy chmelového materiálu se zvýšeným obsahem 8-prenylnaringeninu a chmelový materiál
WO2020144897A1 (ja) * 2019-01-11 2020-07-16 サントリーホールディングス株式会社 イソキサントフモールを含有する組成物の製造方法
WO2020145282A1 (ja) * 2019-01-11 2020-07-16 サントリーホールディングス株式会社 イソキサントフモールを含有する組成物の製造方法
WO2021089840A1 (en) 2019-11-08 2021-05-14 Mrm Health N.V. Fermentation method for the production of phytoestrogens
CN114230541A (zh) * 2021-12-17 2022-03-25 浙江省柑橘研究所 一种柚皮素手性拆分方法、绝对构型确定方法
CN119504731A (zh) * 2024-11-14 2025-02-25 广东省科学院测试分析研究所(中国广州分析测试中心) 一类含1,3,4-噁二唑酰腙结构的柚皮素衍生物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1543834A1 (de) * 2003-12-16 2005-06-22 Biodynamics Herstellung von Hopfenextrakten mit östrogener und antiproliferativer Bioaktivität

Also Published As

Publication number Publication date
US20090227806A1 (en) 2009-09-10
US8067622B2 (en) 2011-11-29
WO2006099914A1 (de) 2006-09-28
DE102005013258B3 (de) 2006-10-12
JP2008538208A (ja) 2008-10-16

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