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WO2005014083A1 - Portable extracorporeal dialysis machine - Google Patents

Portable extracorporeal dialysis machine Download PDF

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Publication number
WO2005014083A1
WO2005014083A1 PCT/IB2004/002650 IB2004002650W WO2005014083A1 WO 2005014083 A1 WO2005014083 A1 WO 2005014083A1 IB 2004002650 W IB2004002650 W IB 2004002650W WO 2005014083 A1 WO2005014083 A1 WO 2005014083A1
Authority
WO
WIPO (PCT)
Prior art keywords
circuit
dialysis
machine
connecting means
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2004/002650
Other languages
French (fr)
Inventor
Marco Crozzoletto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fintech Srl
Original Assignee
Fintech Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fintech Srl filed Critical Fintech Srl
Publication of WO2005014083A1 publication Critical patent/WO2005014083A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • A61M1/1656Apparatus for preparing dialysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1692Detection of blood traces in dialysate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3379Masses, volumes, levels of fluids in reservoirs, flow rates
    • A61M2205/3393Masses, volumes, levels of fluids in reservoirs, flow rates by weighing the reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/50General characteristics of the apparatus with microprocessors or computers

Definitions

  • the present invention relates to a portable extracorporeal dialysis machine.
  • Dialysis treatment is normally performed using extremely complex, bulky machines, and therefore at hospitals under skilled paramedic supervision. This means regular hospital attendance by patients, who are thus committed to a life totally subordinated to treatment .
  • Dialysis machines for home use to eliminate the inconvenience of regular hospital attendance by the patient, exist, but are extremely bulky, still require paramedic supervision, and are difficult to transport.
  • DISCLOSURE OF INVENTION It is an object of the present invention to provide a portable extracorporeal dialysis machine designed to provide a straightforward, low-cost solution to the problems of the known state of the art.
  • a portable extracorporeal dialysis machine comprising a dialysis filter; a circuit for the dialysis solution flowing through said dialysis filter; first connecting means for connecting said circuit to a water source; second connecting means for connecting said circuit to concentrated saline solutions for producing a dialysis solution; third connecting means for connecting the dialysis filter to a patient's blood circuit; and a central control unit to which the machine components are connected; said portable machine being characterized by comprising fourth connecting means located between said first connecting means and the second connecting means, to connect said circuit to a demineralizing assembly; and a control assembly comprising a pump for controlling the ultrafiltration process, and a weighing device for determining the actual weight loss of the patient.
  • Figure 1 shows, schematically, a preferred embodiment of the portable extracorporeal dialysis machine
  • Figure 2 shows a view in perspective of a possible embodiment of the Figure 1 machine.
  • BEST MODE FOR CARRYING OUT THE INVENTION Number 1 in Figure 1 indicates schematically and as a whole the portable machine according to the present invention.
  • Machine 1 comprises a dialysis solution circuit 2; a water connecting member 3 for connecting circuit 2 to a water mains not shown; and a connecting system 4 for connecting a demineralizing assembly 5 comprising cartridges of anionic resin and cationic resin.
  • circuit 2 Downstream from connecting system 4, circuit 2 comprises a 5 ⁇ m sieve 4a; a pressure reducer 6; a water inlet solenoid valve 7; a flow meter 9 for regulating the operating speed of a pump 8 to maintain a constant water flow of 500 ml/min; a degasser 10; and, parallel to degasser 10, a heater 11 and a temperature sensor 12.
  • machine 1 Downstream from degasser 10 and temperature sensor 12, machine 1 comprises two connecting members 13 for connecting circuit 2 by means of two peristaltic pumps 15 to two concentrated solutions 14 - one basic and one acid - for producing the dialysis solution.
  • circuit 2 Downstream from each connecting member, circuit 2 comprises a respective conductimetric sensor 16.
  • circuit 2 comprises a pH-meter 17; a peristaltic water inlet pump 8; a pressure sensor 18; a safety solenoid valve 19; a temperature sensor 20; and a three-way solenoid valve 21 controlling flow of the dialysis solution into a dialysis filter 22.
  • Solenoid valve 21 also controls flow of the dialysis solution into a bypass circuit 23 parallel to dialysis filter 22, and along which, as is known, the dialysis solution is fed when its parameters are not yet all optimum.
  • Machine 1 also comprises two connecting members 24 for connecting filter 22 to a patient's blood circuit not " shown.
  • circuit 2 Downstream from filter 22, circuit 2 comprises a blood loss sensor 25 followed by a second three-way solenoid valve 26 to which bypass circuit 23 is also connected. Downstream from second solenoid valve 26, circuit 2 comprises a "T" connecting member 27 for directing the dialysis solution from filter 22 along two branches. A first part of the dialysis solution from the filter is pumped along circuit 2, and eventually drained, by a peristaltic pump 28 set to also permit liquid withdrawal and therefore weight reduction of the patient; and a second part of the solution is fed to a control assembly 29 comprising a pressure sensor 30, a peristaltic pump 31, a flow meter 32, and a load cell 33 in which graduated bags containing the ultrafiltrate are weighed to give the patient an immediate indication of the actual weight loss.
  • Machine 1 also comprises a connecting member 34 located along circuit 2 , downstream from connecting system 4 and upstream from pressure reducer 6, to connect circuit 2 to a disinfectant solution 35.
  • machine 1 comprises a central control unit 36 for controlling all the components referred to above, for setting operating values, and for controlling the signals from sensors such as the pH-meter, flow meters, and conductimetric sensors; a monitor 37 for displaying operation of the various components and the information recorded by central control unit 36; and a known operating current generator or connector not shown or described for the sake of simplicity.
  • Machine 1 weighs less than 15 kg, and may be in the form of a compact case 38 ( Figure 2) , the bottom portion 38a of which houses and conceals circuit 2 as described above, and the top portion 38b of which houses central control unit 36 and monitor 37.
  • Central control unit 36 and monitor 37 may be formed in one unit, which may removed from its seat and remains connected to the seat by a lead for easy manual use.
  • the machine according to the present invention has the big advantage of being portable, and of not requiring devices external to the machine for constantly weighing the patient, or other external devices for performing the dialysis treatment.
  • the machine in fact comprises everything required for diffusive dialysis with no paramedic supervision, is compact and lightweight enough to be carried easily, and so provides for a more normal life of the patient despite the necessity for constant treatment.
  • the machine comprises various safety components, such as the weighing system, and a demineralizing assembly can be connected for use with any available drinking water source.

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

A portable extracorporeal dialysis machine (1) in the form of a case, and including a dialysis filter (22); a circuit (2) for the dialysis solution flowing through the dialysis filter (22); first connecting means (3) for connecting the circuit to a water source; second connecting means (13) for connecting the circuit (2) to concentrated saline solutions (14) for producing a dialysis solution; a control assembly (29) located downstream from the dialysis filter to control the liquid withdrawn from the patient; third connecting means (24) for connecting the dialysis filter to a patient's blood circuit; a central control unit (36) to which the machine components are connected; and fourth connecting means (4) located between the first (3) and second (13) connecting means, to connect the circuit (2) to a demineralizing assembly (5).

Description

PORTABLE EXTRACORPOREAL DIALYSIS MACHINE
TECHNICAL FIELD The present invention relates to a portable extracorporeal dialysis machine. BACKGROUND ART Dialysis treatment is normally performed using extremely complex, bulky machines, and therefore at hospitals under skilled paramedic supervision. This means regular hospital attendance by patients, who are thus committed to a life totally subordinated to treatment . Dialysis machines for home use, to eliminate the inconvenience of regular hospital attendance by the patient, exist, but are extremely bulky, still require paramedic supervision, and are difficult to transport. DISCLOSURE OF INVENTION It is an object of the present invention to provide a portable extracorporeal dialysis machine designed to provide a straightforward, low-cost solution to the problems of the known state of the art. According to the present invention, there is provided a portable extracorporeal dialysis machine comprising a dialysis filter; a circuit for the dialysis solution flowing through said dialysis filter; first connecting means for connecting said circuit to a water source; second connecting means for connecting said circuit to concentrated saline solutions for producing a dialysis solution; third connecting means for connecting the dialysis filter to a patient's blood circuit; and a central control unit to which the machine components are connected; said portable machine being characterized by comprising fourth connecting means located between said first connecting means and the second connecting means, to connect said circuit to a demineralizing assembly; and a control assembly comprising a pump for controlling the ultrafiltration process, and a weighing device for determining the actual weight loss of the patient. BRIEF DESCRIPTION OF THE DRAWINGS A non-limiting embodiment of the invention will be described by way of example with reference to the accompanying drawings, in which: Figure 1 shows, schematically, a preferred embodiment of the portable extracorporeal dialysis machine; Figure 2 shows a view in perspective of a possible embodiment of the Figure 1 machine. BEST MODE FOR CARRYING OUT THE INVENTION Number 1 in Figure 1 indicates schematically and as a whole the portable machine according to the present invention. Machine 1 comprises a dialysis solution circuit 2; a water connecting member 3 for connecting circuit 2 to a water mains not shown; and a connecting system 4 for connecting a demineralizing assembly 5 comprising cartridges of anionic resin and cationic resin. Downstream from connecting system 4, circuit 2 comprises a 5 μm sieve 4a; a pressure reducer 6; a water inlet solenoid valve 7; a flow meter 9 for regulating the operating speed of a pump 8 to maintain a constant water flow of 500 ml/min; a degasser 10; and, parallel to degasser 10, a heater 11 and a temperature sensor 12. Downstream from degasser 10 and temperature sensor 12, machine 1 comprises two connecting members 13 for connecting circuit 2 by means of two peristaltic pumps 15 to two concentrated solutions 14 - one basic and one acid - for producing the dialysis solution. Downstream from each connecting member, circuit 2 comprises a respective conductimetric sensor 16. Continuing in the dialysis solution flow direction, circuit 2 comprises a pH-meter 17; a peristaltic water inlet pump 8; a pressure sensor 18; a safety solenoid valve 19; a temperature sensor 20; and a three-way solenoid valve 21 controlling flow of the dialysis solution into a dialysis filter 22. Solenoid valve 21 also controls flow of the dialysis solution into a bypass circuit 23 parallel to dialysis filter 22, and along which, as is known, the dialysis solution is fed when its parameters are not yet all optimum. Machine 1 also comprises two connecting members 24 for connecting filter 22 to a patient's blood circuit not "shown. Downstream from filter 22, circuit 2 comprises a blood loss sensor 25 followed by a second three-way solenoid valve 26 to which bypass circuit 23 is also connected. Downstream from second solenoid valve 26, circuit 2 comprises a "T" connecting member 27 for directing the dialysis solution from filter 22 along two branches. A first part of the dialysis solution from the filter is pumped along circuit 2, and eventually drained, by a peristaltic pump 28 set to also permit liquid withdrawal and therefore weight reduction of the patient; and a second part of the solution is fed to a control assembly 29 comprising a pressure sensor 30, a peristaltic pump 31, a flow meter 32, and a load cell 33 in which graduated bags containing the ultrafiltrate are weighed to give the patient an immediate indication of the actual weight loss. Machine 1 also comprises a connecting member 34 located along circuit 2 , downstream from connecting system 4 and upstream from pressure reducer 6, to connect circuit 2 to a disinfectant solution 35. Finally, machine 1 comprises a central control unit 36 for controlling all the components referred to above, for setting operating values, and for controlling the signals from sensors such as the pH-meter, flow meters, and conductimetric sensors; a monitor 37 for displaying operation of the various components and the information recorded by central control unit 36; and a known operating current generator or connector not shown or described for the sake of simplicity. Machine 1 weighs less than 15 kg, and may be in the form of a compact case 38 (Figure 2) , the bottom portion 38a of which houses and conceals circuit 2 as described above, and the top portion 38b of which houses central control unit 36 and monitor 37. Central control unit 36 and monitor 37 may be formed in one unit, which may removed from its seat and remains connected to the seat by a lead for easy manual use. As will be obvious from the foregoing description, the machine according to the present invention has the big advantage of being portable, and of not requiring devices external to the machine for constantly weighing the patient, or other external devices for performing the dialysis treatment. The machine in fact comprises everything required for diffusive dialysis with no paramedic supervision, is compact and lightweight enough to be carried easily, and so provides for a more normal life of the patient despite the necessity for constant treatment. For which purpose, the machine comprises various safety components, such as the weighing system, and a demineralizing assembly can be connected for use with any available drinking water source.

Claims

1) A portable extracorporeal dialysis machine (1) comprising a dialysis filter (22); a circuit (2) for the dialysis solution flowing through said dialysis filter (22) ; first connecting means (3) for connecting said circuit to a water source; second connecting means (13) for connecting said circuit (2) to concentrated saline solutions (14) for producing a dialysis solution; third connecting means (24) for connecting the dialysis filter to a patient's blood circuit; and a central control unit (36) to which the machine components are connected; said portable machine being characterized by comprising fourth connecting means (4) located between said first connecting means (3) and the second connecting means (13), to connect said circuit (2) to a demineralizing assembly (5) ; and a control assembly (29) comprising a pump (31) for controlling the ultrafiltration process, and a weighing device (33) for determining the actual weight loss of the patient. 2) A machine as claimed in Claim 1, characterized by comprising a monitor (37) connected to said central control unit (36) . 3) A machine as claimed in any one of the foregoing Claims, characterized by being in the form of a compact case (38) , a bottom portion (38a) of which houses and conceals said circuit (2), and a top portion (38b) of which houses said central control unit (36) . 4) A machine as claimed in Claims 4 and 2, characterized in that said top portion (38b) houses said monitor (37) .
PCT/IB2004/002650 2003-08-12 2004-08-11 Portable extracorporeal dialysis machine Ceased WO2005014083A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000009A ITRI20030009A1 (en) 2003-08-12 2003-08-12 PORTABLE DEVICE FOR EXTRACORPAL DIALYSIS.
ITRI2003A000009 2003-08-12

Publications (1)

Publication Number Publication Date
WO2005014083A1 true WO2005014083A1 (en) 2005-02-17

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ID=34131239

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/002650 Ceased WO2005014083A1 (en) 2003-08-12 2004-08-11 Portable extracorporeal dialysis machine

Country Status (2)

Country Link
IT (1) ITRI20030009A1 (en)
WO (1) WO2005014083A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8425767B2 (en) 2007-05-25 2013-04-23 Gambro Lundia Ab Device for connecting to a liquid source

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434786A (en) * 1973-04-02 1976-05-05 Lichtenstein E S Apparatus including disposable array for processing body fluids
US4229299A (en) * 1978-03-22 1980-10-21 Hoechst Aktiengesellschaft Peristaltic dialysate solution pump
US4765888A (en) * 1980-11-13 1988-08-23 Hospal Industrie Artificial kidney with integrated dialysate circuit
US20010004523A1 (en) * 1999-12-02 2001-06-21 Antonio Bosetto Method for determining a parameter indicative of the progress of an extracorporeal blood treatment

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434786A (en) * 1973-04-02 1976-05-05 Lichtenstein E S Apparatus including disposable array for processing body fluids
US4229299A (en) * 1978-03-22 1980-10-21 Hoechst Aktiengesellschaft Peristaltic dialysate solution pump
US4765888A (en) * 1980-11-13 1988-08-23 Hospal Industrie Artificial kidney with integrated dialysate circuit
US20010004523A1 (en) * 1999-12-02 2001-06-21 Antonio Bosetto Method for determining a parameter indicative of the progress of an extracorporeal blood treatment

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8425767B2 (en) 2007-05-25 2013-04-23 Gambro Lundia Ab Device for connecting to a liquid source

Also Published As

Publication number Publication date
ITRI20030009A1 (en) 2005-02-13

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