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WO2005012364A3 - Matrice complexe a usage biomedical - Google Patents

Matrice complexe a usage biomedical Download PDF

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Publication number
WO2005012364A3
WO2005012364A3 PCT/FR2004/002052 FR2004002052W WO2005012364A3 WO 2005012364 A3 WO2005012364 A3 WO 2005012364A3 FR 2004002052 W FR2004002052 W FR 2004002052W WO 2005012364 A3 WO2005012364 A3 WO 2005012364A3
Authority
WO
WIPO (PCT)
Prior art keywords
polymer
complex matrix
molecular weight
chains
natural origin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2004/002052
Other languages
English (en)
Other versions
WO2005012364A2 (fr
Inventor
Laurence Hermitte
Olivier Benoit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anteis SA
Original Assignee
Anteis SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anteis SA filed Critical Anteis SA
Priority to US10/565,442 priority Critical patent/US20060246137A1/en
Priority to EP04786014A priority patent/EP1648942A2/fr
Priority to AU2004261752A priority patent/AU2004261752B2/en
Priority to CN2004800216528A priority patent/CN1829743B/zh
Priority to BRPI0413086-3A priority patent/BRPI0413086A/pt
Priority to JP2006521630A priority patent/JP2007500027A/ja
Priority to CA002534033A priority patent/CA2534033A1/fr
Publication of WO2005012364A2 publication Critical patent/WO2005012364A2/fr
Publication of WO2005012364A3 publication Critical patent/WO2005012364A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

L'invention concerne une matrice complexe constituée d'au moins un polymère biocompatible d'origine naturelle, réticulée et sur laquelle sont greffées des petites chaînes de poids moléculaire inférieur à 50 000 Da avec un taux de greffage de 10 à 40 %, ainsi qu'un procédé de préparation d'une matrice biocompatible peu dégradable constituée d'au moins un polymère d'origine naturelle, consistant : d'une part, à greffer de petites chaînes de poids moléculaire inférieur à 10 000 Da, avec un taux de greffage de 10 à 40 %, d'autre part, à réticuler les chaînes principales du polymère entre elles, pour créer une matrice homogène.
PCT/FR2004/002052 2003-07-30 2004-07-30 Matrice complexe a usage biomedical Ceased WO2005012364A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US10/565,442 US20060246137A1 (en) 2003-07-30 2004-07-30 Complex matrix for biomedical use
EP04786014A EP1648942A2 (fr) 2003-07-30 2004-07-30 Matrice complexe a usage biomedical
AU2004261752A AU2004261752B2 (en) 2003-07-30 2004-07-30 Complex matrix for biomedical use
CN2004800216528A CN1829743B (zh) 2003-07-30 2004-07-30 生物医用的复合基质
BRPI0413086-3A BRPI0413086A (pt) 2003-07-30 2004-07-30 matriz complexa, utilização da mesma, e processo de preparação de uma matriz biocompatìvel pouco biodegradável
JP2006521630A JP2007500027A (ja) 2003-07-30 2004-07-30 生物医学的な使用のための複合マトリックス
CA002534033A CA2534033A1 (fr) 2003-07-30 2004-07-30 Matrice complexe a usage biomedical

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0309401 2003-07-30
FR0309401 2003-07-30

Publications (2)

Publication Number Publication Date
WO2005012364A2 WO2005012364A2 (fr) 2005-02-10
WO2005012364A3 true WO2005012364A3 (fr) 2005-06-02

Family

ID=34112706

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2004/002052 Ceased WO2005012364A2 (fr) 2003-07-30 2004-07-30 Matrice complexe a usage biomedical

Country Status (10)

Country Link
US (1) US20060246137A1 (fr)
EP (1) EP1648942A2 (fr)
JP (1) JP2007500027A (fr)
KR (1) KR20070012306A (fr)
CN (1) CN1829743B (fr)
AU (1) AU2004261752B2 (fr)
BR (1) BRPI0413086A (fr)
CA (1) CA2534033A1 (fr)
RU (1) RU2360928C2 (fr)
WO (1) WO2005012364A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9228027B2 (en) 2008-09-02 2016-01-05 Allergan Holdings France S.A.S. Threads of Hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof

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MXPA05002361A (es) 2002-08-28 2005-09-30 Inamed Medical Products Corp Dispositivo de banda gastrica resistente a la fatiga.
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
ATE526887T1 (de) 2004-01-23 2011-10-15 Allergan Inc Lösbar befestigbares, einteiliges, verstellbares magenband
CA2559056A1 (fr) 2004-03-08 2005-09-22 Endoart S.A. Systeme de fermeture pour organes tubulaires
CA2569043C (fr) 2004-03-18 2010-08-17 Allergan, Inc. Appareil et procede de reglage du volume de ballons intragastriques
US8251888B2 (en) 2005-04-13 2012-08-28 Mitchell Steven Roslin Artificial gastric valve
US8043206B2 (en) 2006-01-04 2011-10-25 Allergan, Inc. Self-regulating gastric band with pressure data processing
US7798954B2 (en) 2006-01-04 2010-09-21 Allergan, Inc. Hydraulic gastric band with collapsible reservoir
ES2399134T3 (es) 2006-03-08 2013-03-26 Purac Biochem Bv Método para preparar un complejo de una amina orgánica y ácido láctico
FR2909285A1 (fr) * 2006-12-01 2008-06-06 Anteis Sa "utilisation d'un gel anti-adhesif et anti fibrotique"
BRPI0811784A2 (pt) 2007-05-23 2011-05-10 Allergan Inc colÁgeno reticulado e uso do mesmo
US8318695B2 (en) 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
BRPI0819075A2 (pt) 2007-11-16 2014-10-07 Vicept Therapeutics Inc Método para tratar púrpura em um indivíduo e método para diminuir a púrpura em um indivíduo antes de um procedimento cirúrgico
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
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US8450475B2 (en) * 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
AU2015252122A1 (en) * 2008-08-04 2015-11-26 Allergan Industrie Sas Hyaluronic acid-based gels including anesthetic agents
US20100305397A1 (en) * 2008-10-06 2010-12-02 Allergan Medical Sarl Hydraulic-mechanical gastric band
WO2010042493A1 (fr) 2008-10-06 2010-04-15 Allergan, Inc. Bande gastrique mécanique avec coussins
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FR2938187B1 (fr) 2008-11-07 2012-08-17 Anteis Sa Composition injectable a base d'acide hyaluronique ou l'un de ses sels, de polyols et de lidocaine, sterilisee a la chaleur
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US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US8758221B2 (en) 2010-02-24 2014-06-24 Apollo Endosurgery, Inc. Source reservoir with potential energy for remotely adjustable gastric banding system
US8840541B2 (en) * 2010-02-25 2014-09-23 Apollo Endosurgery, Inc. Pressure sensing gastric banding system
CA2792729C (fr) 2010-03-12 2016-06-28 Allergan Industrie, Sas Composition fluide pour l'amelioration d'etats cutanes
DK2550027T4 (da) 2010-03-22 2019-05-13 Allergan Inc Tværbundne polysaccharid- og protein-polysaccharid-hydrogeler til blødvævsforøgelse
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EP3653232A1 (fr) 2015-02-13 2020-05-20 Allergan Industrie, SAS Implants pour sculpter, augmenter ou corriger des caractéristiques faciales telles que le menton
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WO1987007898A1 (fr) * 1986-06-18 1987-12-30 Pharmacia Ab Materiau forme de polysaccharides contenant des groupes carboxyles, et procede de production de ces polysaccharides
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EP0341745A1 (fr) * 1988-05-13 1989-11-15 FIDIA S.p.A. Polysaccharides carboxylés réticulés
EP0749982A1 (fr) * 1995-06-22 1996-12-27 Hercules Incorporated Polysaccharides greffés avec des antioxydants et leurs utilisation
EP0939086A1 (fr) * 1998-02-27 1999-09-01 Stichting Hippomedics Procédé pour préparer un acide hyaluronique réticulé
WO2000046252A1 (fr) * 1999-02-05 2000-08-10 Vitrolife Uk Limited Procede de reticulation d'acide hyaluronique avec des polymeres
WO2002006350A1 (fr) * 2000-07-19 2002-01-24 Laboratoires D'esthetique Appliquee Reticulation de polysaccharide(s), preparation d'hydrogel(s), polysaccharide(s) et hydrogel(s) obtenu(s), leurs utilisations.

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Patent Citations (9)

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US4605691A (en) * 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
WO1987007898A1 (fr) * 1986-06-18 1987-12-30 Pharmacia Ab Materiau forme de polysaccharides contenant des groupes carboxyles, et procede de production de ces polysaccharides
US4963666A (en) * 1986-06-18 1990-10-16 Pharmacia Ab Material of polysaccharides containing carboxyl groups, and a process for producing such polysaccharides
EP0265116A2 (fr) * 1986-10-13 1988-04-27 FIDIA S.p.A. Esters réticulés d'acide hyaluronique
EP0341745A1 (fr) * 1988-05-13 1989-11-15 FIDIA S.p.A. Polysaccharides carboxylés réticulés
EP0749982A1 (fr) * 1995-06-22 1996-12-27 Hercules Incorporated Polysaccharides greffés avec des antioxydants et leurs utilisation
EP0939086A1 (fr) * 1998-02-27 1999-09-01 Stichting Hippomedics Procédé pour préparer un acide hyaluronique réticulé
WO2000046252A1 (fr) * 1999-02-05 2000-08-10 Vitrolife Uk Limited Procede de reticulation d'acide hyaluronique avec des polymeres
WO2002006350A1 (fr) * 2000-07-19 2002-01-24 Laboratoires D'esthetique Appliquee Reticulation de polysaccharide(s), preparation d'hydrogel(s), polysaccharide(s) et hydrogel(s) obtenu(s), leurs utilisations.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9228027B2 (en) 2008-09-02 2016-01-05 Allergan Holdings France S.A.S. Threads of Hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof

Also Published As

Publication number Publication date
US20060246137A1 (en) 2006-11-02
RU2360928C2 (ru) 2009-07-10
WO2005012364A2 (fr) 2005-02-10
EP1648942A2 (fr) 2006-04-26
AU2004261752A1 (en) 2005-02-10
CN1829743B (zh) 2010-06-30
CA2534033A1 (fr) 2005-02-10
KR20070012306A (ko) 2007-01-25
JP2007500027A (ja) 2007-01-11
AU2004261752B2 (en) 2010-10-28
BRPI0413086A (pt) 2006-10-03
CN1829743A (zh) 2006-09-06
RU2006102198A (ru) 2007-08-20

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