[go: up one dir, main page]

WO2005079427A3 - Porous hybrid monolith materials with organic groups removed from the surface - Google Patents

Porous hybrid monolith materials with organic groups removed from the surface Download PDF

Info

Publication number
WO2005079427A3
WO2005079427A3 PCT/US2005/004955 US2005004955W WO2005079427A3 WO 2005079427 A3 WO2005079427 A3 WO 2005079427A3 US 2005004955 W US2005004955 W US 2005004955W WO 2005079427 A3 WO2005079427 A3 WO 2005079427A3
Authority
WO
WIPO (PCT)
Prior art keywords
organic groups
improved
stability
chromatographic
groups removed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/004955
Other languages
French (fr)
Other versions
WO2005079427A2 (en
Inventor
John E O'gara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Waters Investments Ltd
Original Assignee
Waters Investments Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Waters Investments Ltd filed Critical Waters Investments Ltd
Priority to GB0615709A priority Critical patent/GB2427611A/en
Priority to JP2006553361A priority patent/JP2007523331A/en
Priority to DE112005000269T priority patent/DE112005000269T5/en
Priority to US10/587,598 priority patent/US20070215547A1/en
Publication of WO2005079427A2 publication Critical patent/WO2005079427A2/en
Publication of WO2005079427A3 publication Critical patent/WO2005079427A3/en
Anticipated expiration legal-status Critical
Priority to US14/188,149 priority patent/US20140166581A1/en
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
    • B01J20/103—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate comprising silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28042—Shaped bodies; Monolithic structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28057—Surface area, e.g. B.E.T specific surface area
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28069—Pore volume, e.g. total pore volume, mesopore volume, micropore volume
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B01J20/28083—Pore diameter being in the range 2-50 nm, i.e. mesopores
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/283—Porous sorbents based on silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J43/00—Amphoteric ion-exchange, i.e. using ion-exchangers having cationic and anionic groups; Use of material as amphoteric ion-exchangers; Treatment of material for improving their amphoteric ion-exchange properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B3/00—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form
    • B32B3/10—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by a discontinuous layer, i.e. formed of separate pieces of material
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/04—Polysiloxanes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/14—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers in which at least two but not all the silicon atoms are connected by linkages other than oxygen atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/80—Aspects related to sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J2220/82—Shaped bodies, e.g. monoliths, plugs, tubes, continuous beds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/524—Physical parameters structural properties
    • G01N2030/528—Monolithic sorbent material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/249921—Web or sheet containing structurally defined element or component
    • Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)

Abstract

A material for chromatographic separations, processes for its preparation, and separation devices containing the chromatographic material. In particular, porous inorganic/organic hybrid monoliths are provided with a decreased concentration of surface organic groups, and have improved pH stability, improved chromatographic separation performance, and improved packed bed stability. These monoliths may be surface modified resulting in higher bonded phase surface concentrations and have enhanced stability at low pH.
PCT/US2005/004955 2004-02-17 2005-02-16 Porous hybrid monolith materials with organic groups removed from the surface Ceased WO2005079427A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB0615709A GB2427611A (en) 2004-02-17 2005-02-16 Porous hybrid monolith materials with organic groups removed from the surface
JP2006553361A JP2007523331A (en) 2004-02-17 2005-02-16 Porous hybrid monolithic material with organic groups removed from the surface
DE112005000269T DE112005000269T5 (en) 2004-02-17 2005-02-16 Porous hybrid monolith materials with surface removed organic groups
US10/587,598 US20070215547A1 (en) 2004-02-17 2005-02-16 Porous Hybrid Monolith Materials With Organic Groups Removed From the Surface
US14/188,149 US20140166581A1 (en) 2004-02-17 2014-02-24 Porous hybrid monolith materials with organic groups removed from the surface

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54559004P 2004-02-17 2004-02-17
US60/545,590 2004-02-17

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10/587,598 A-371-Of-International US20070215547A1 (en) 2004-02-17 2005-02-16 Porous Hybrid Monolith Materials With Organic Groups Removed From the Surface
US14/188,149 Continuation US20140166581A1 (en) 2004-02-17 2014-02-24 Porous hybrid monolith materials with organic groups removed from the surface

Publications (2)

Publication Number Publication Date
WO2005079427A2 WO2005079427A2 (en) 2005-09-01
WO2005079427A3 true WO2005079427A3 (en) 2006-01-12

Family

ID=34886173

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/004955 Ceased WO2005079427A2 (en) 2004-02-17 2005-02-16 Porous hybrid monolith materials with organic groups removed from the surface

Country Status (5)

Country Link
US (2) US20070215547A1 (en)
JP (1) JP2007523331A (en)
DE (1) DE112005000269T5 (en)
GB (1) GB2427611A (en)
WO (1) WO2005079427A2 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6686035B2 (en) 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
US6528167B2 (en) * 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface
US7250214B2 (en) 2001-08-09 2007-07-31 Waters Investments Limited Porous inorganic/organic hybrid monolith materials for chromatographic separations and process for their preparation
DE10393599T5 (en) 2002-10-30 2005-10-27 Waters Investments Ltd., New Castle Porous inorganic / organic homogeneous hybrid copolymeric materials for chromatographic separations and methods for their preparation
JP4538785B2 (en) * 2004-03-31 2010-09-08 和樹 中西 Method for producing organic-inorganic hybrid porous material
US10773186B2 (en) 2004-07-30 2020-09-15 Waters Technologies Corporation Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation
JP5308665B2 (en) 2004-07-30 2013-10-09 ウオーターズ・テクノロジーズ・コーポレイシヨン Porous inorganic / organic hybrid materials with ordered domains for chromatographic separation and methods for their preparation
FR2884253B1 (en) * 2005-04-08 2007-06-22 Univ Lille Sciences Tech FUNCTIONALIZABLE MONOLITHIC MATERIALS
US8697765B2 (en) 2007-01-12 2014-04-15 Waters Technologies Corporation Porous carbon-heteroatom-silicon hybrid inorganic/organic materials for chromatographic separations and process for the preparation thereof
FR2912400B1 (en) * 2007-02-14 2009-04-17 Univ Paris Curie HYBRID ALVEOLA MATERIAL, PROCESS FOR PREPARING THE SAME
US9120083B2 (en) * 2007-02-21 2015-09-01 Waters Technologies Corporation Porous inorganic/organic hybrid particles having high organic content and enhanced pore geometry for chromatographic separations
US8795410B2 (en) * 2007-06-18 2014-08-05 Gl Sciences Incorporated Monolith adsorbent and method and apparatus for adsorbing samples with the same
US8314201B2 (en) 2007-11-30 2012-11-20 The United States Of America As Represented By The Administration Of The National Aeronautics And Space Administration Highly porous ceramic oxide aerogels having improved flexibility
US8258251B2 (en) * 2007-11-30 2012-09-04 The United States Of America, As Represented By The Administrator Of The National Aeronautics And Space Administration Highly porous ceramic oxide aerogels having improved flexibility
US8435410B2 (en) * 2008-04-01 2013-05-07 Georgia State University Research Foundation, Inc. Surfactant-based monolithic columns, methods for making the same, and method for using the same
US7915318B2 (en) * 2008-09-09 2011-03-29 General Electric Company Aqueous ROMP-based monolith materials and methods for making
US11291974B2 (en) 2009-06-01 2022-04-05 Waters Technologies Corporation Hybrid inorganic/organic materials having novel surface modification; process for the preparation of inorganic/organic hybrid materials; and use of said particles for chromatographic separations
US11439977B2 (en) 2009-06-01 2022-09-13 Waters Technologies Corporation Hybrid material for chromatographic separations comprising a superficially porous core and a surrounding material
DE102009040182A1 (en) * 2009-09-07 2011-03-24 Dionex Benelux B.V. separating body
JP2012000552A (en) * 2010-06-15 2012-01-05 Asahi Kasei Chemicals Corp Method of manufacturing of protein adsorbent
EP2598440B1 (en) 2010-07-26 2020-12-30 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
WO2012170755A1 (en) 2011-06-09 2012-12-13 Waters Technologies Corporation A porous material and devices for performing separations, filtrations, and catalysis and ek pumps, and methods of making and using the same
JP6401151B2 (en) 2012-05-15 2018-10-03 ウオーターズ・テクノロジーズ・コーポレイシヨン Chromatographic material
WO2014058570A1 (en) 2012-09-17 2014-04-17 Alltech Associates, Inc. Chromatography media and devices
US11389783B2 (en) 2014-05-02 2022-07-19 W.R. Grace & Co.-Conn. Functionalized support material and methods of making and using functionalized support material
CN104211156B (en) * 2014-08-14 2016-05-04 中国科学院沈阳应用生态研究所 A kind of acid waste water Fe that removes3+The method of acidity
GB2549417B (en) * 2015-01-15 2020-10-21 Dionex Corp Chromatographic material having improved PH stability, method for preparation thereof and uses thereof
JP2018517559A (en) 2015-06-05 2018-07-05 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ Adsorbing bioprocess clarifier and method for producing and using the same
CN109070053A (en) 2016-03-06 2018-12-21 沃特世科技公司 Porous material with controlled porosity for chromatographic separation; process for its preparation; and use thereof
EP4354134A3 (en) * 2018-10-02 2024-07-24 Waters Technologies Corporation Sorbents, devices, kits and methods useful for biological sample treatment
CN109926034B (en) * 2019-04-04 2021-08-03 中国科学院兰州化学物理研究所 Preparation and application of an amphiphilic ionic liquid modified silica gel chromatography packing
CN114618455A (en) * 2020-12-11 2022-06-14 中国科学院大连化学物理研究所 Reversed phase chromatographic stationary phase embedded by multi-polar functional groups and preparation and application thereof
US20220362741A1 (en) * 2021-04-29 2022-11-17 Waters Technologies Corporation Hydrolytically stable zwitterionic chromatographic materials

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528167B2 (en) * 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US517728A (en) * 1894-04-03 Nut-lock
US519433A (en) * 1894-05-08 Thomas c
US3935299A (en) * 1972-05-11 1976-01-27 Andrei Vladimirovich Kiselev Process for preparation of wide-pore adsorbent for use in chromatography
DE2236862C2 (en) * 1972-07-27 1974-09-05 Istvan Prof. Dr. 6600 Saarbruecken Halasz Sorbents for chromatography
DE2357184A1 (en) * 1973-11-16 1975-05-22 Merck Patent Gmbh PROCESS FOR THE PRODUCTION OF ORGANICALLY MODIFIED SILICON DIOXIDES
US4029583A (en) * 1975-02-28 1977-06-14 Purdue Research Foundation Chromatographic supports and methods and apparatus for preparing the same
CS179184B1 (en) * 1975-07-25 1977-10-31 Stanislav Vozka Method for preparation of precisely spherical particles of silica gel with controlled size and controled size pores.
DE2642032C2 (en) * 1976-09-18 1987-04-30 Rupprecht, Herbert, Prof. Dr., 8400 Regensburg Process for incorporating active ingredients into silicon dioxide-containing carrier materials and a silicon dioxide-containing preparation
FR2464967A1 (en) * 1979-09-07 1981-03-20 Rhone Poulenc Ind PREPARATION OF ANION EXCHANGE RESINS BY BROMATION OF VINYLAROMATIC POLYMERS
US4324689A (en) * 1980-02-26 1982-04-13 Shah Ramesh M High carbon content chromatographic packing and method for making same
US4724207A (en) * 1984-02-02 1988-02-09 Cuno Incorporated Modified siliceous chromatographic supports
DE3616133A1 (en) * 1985-09-25 1987-11-19 Merck Patent Gmbh SPHERICAL SIO (DOWN ARROW) 2 (DOWN ARROW) PARTICLES
US5108595A (en) * 1985-11-01 1992-04-28 E. I. Du Pont De Nemours And Company Porous silica microspheres having silanol-enriched and silanized surfaces
GB8618322D0 (en) * 1986-07-28 1986-09-03 3I Res Expl Ltd Bonded chromotographic stationary phase
US5256386A (en) * 1987-06-29 1993-10-26 Eka Nobel Ab Method for preparation of silica particles
US4889632A (en) * 1987-12-10 1989-12-26 Ceskoslovenska Akademie Ved Macroporous polymeric membranes for the separation of polymers and a method of their application
EP0386926A3 (en) * 1989-03-02 1991-12-18 Supelco, Inc. Silica gel supports suitable for chromatographic separations
US6022902A (en) * 1989-10-31 2000-02-08 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Porous article with surface functionality and method for preparing same
US4983369A (en) * 1989-11-22 1991-01-08 Allied-Signal Inc. Process for forming highly uniform silica spheres
US5068387A (en) * 1989-12-01 1991-11-26 Dow Corning Corporation Production of organofunctional alkoxysilanes
US5271833A (en) * 1990-03-22 1993-12-21 Regents Of The University Of Minnesota Polymer-coated carbon-clad inorganic oxide particles
US5076980A (en) * 1990-08-01 1991-12-31 Geltech, Inc. Method of making sol-gel monoliths
JP2646150B2 (en) * 1990-08-27 1997-08-25 出光興産 株式会社 Water repellent silica sol and method for producing the same
US5071565A (en) * 1991-02-04 1991-12-10 Iowa State University Research Foundation, Inc. Modified resins for solid-phase extraction
DE69211010T2 (en) * 1991-10-21 1997-01-23 Cornell Res Foundation Inc Chromography column with macroporous polymer filling
US5734020A (en) * 1991-11-20 1998-03-31 Cpg, Inc. Production and use of magnetic porous inorganic materials
US5565142A (en) * 1992-04-01 1996-10-15 Deshpande; Ravindra Preparation of high porosity xerogels by chemical surface modification.
DE69304695T2 (en) * 1992-05-20 1997-03-20 Du Pont METHOD FOR PRODUCING INORGANIC GELS
US5298833A (en) * 1992-06-22 1994-03-29 Copytele, Inc. Black electrophoretic particles for an electrophoretic image display
US5374755A (en) * 1992-07-17 1994-12-20 Millipore Corporation Liquid chromatography stationary phases with reduced silanol interactions
US5378790A (en) * 1992-09-16 1995-01-03 E. I. Du Pont De Nemours & Co. Single component inorganic/organic network materials and precursors thereof
US5498678A (en) * 1992-12-21 1996-03-12 Rohm And Haas Company Suspension polymerization process for water-soluble monomers
DE69407295T2 (en) * 1993-07-19 1998-06-25 Merck Patent Gmbh, 64293 Darmstadt INORGANIC, POROUS MATERIAL AND METHOD FOR THE PRODUCTION THEREOF
US5425930A (en) * 1993-09-17 1995-06-20 Alliedsignal Inc. Process for forming large silica spheres by low temperature nucleation
DE69425473T3 (en) * 1993-11-05 2005-11-03 Shin-Etsu Chemical Co., Ltd. Process for the preparation of organopolysiloxanes containing organofunctional groups and organopolysiloxanes prepared therefrom, organopolysiloxanes containing mercapto and alkoxy groups and processes for their preparation
US5591453A (en) * 1994-07-27 1997-01-07 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses
US5728457A (en) * 1994-09-30 1998-03-17 Cornell Research Foundation, Inc. Porous polymeric material with gradients
US5868966A (en) * 1995-03-30 1999-02-09 Drexel University Electroactive inorganic organic hybrid materials
US5637135A (en) * 1995-06-26 1997-06-10 Capillary Technology Corporation Chromatographic stationary phases and adsorbents from hybrid organic-inorganic sol-gels
US5667674A (en) * 1996-01-11 1997-09-16 Minnesota Mining And Manufacturing Company Adsorption medium and method of preparing same
JP3818689B2 (en) * 1996-01-16 2006-09-06 富士写真フイルム株式会社 Aqueous dispersion of core / shell composite particles having colloidal silica as the core and organic polymer as the shell, and method for producing the same
US5869152A (en) * 1996-03-01 1999-02-09 The Research Foundation Of State University Of New York Silica materials
US5965202A (en) * 1996-05-02 1999-10-12 Lucent Technologies, Inc. Hybrid inorganic-organic composite for use as an interlayer dielectric
US6313219B1 (en) * 1996-05-02 2001-11-06 Lucent Technologies, Inc. Method for hybrid inorganic/organic composite materials
US5853886A (en) * 1996-06-17 1998-12-29 Claytec, Inc. Hybrid nanocomposites comprising layered inorganic material and methods of preparation
ES2183236T3 (en) * 1996-12-26 2003-03-16 Merck Patent Gmbh PROCEDURE FOR THE PRODUCTION OF INORGANIC MATERIALS.
US5976479A (en) * 1996-12-30 1999-11-02 Uop Llc Hydrothermal process for preparing a unimodal large pore silica
AU7965698A (en) * 1997-06-13 1998-12-30 California Institute Of Technology Porous silica having spatially organized organic functionalities
US6027643A (en) * 1997-09-04 2000-02-22 Dionex Corporation Ion chromatographic method and apparatus using a combined suppressor and eluent generator
US6136187A (en) * 1997-12-09 2000-10-24 The Board Of Trustees Of The Leland Stanford Junior University Separation column containing porous matrix and method of packing column
DE19756831A1 (en) * 1997-12-19 1999-07-01 Wacker Chemie Gmbh Silicon dioxide, which carries partially or completely silylated polysilicic acid chains on its surface
US6281257B1 (en) * 1998-04-27 2001-08-28 The Regents Of The University Of Michigan Porous composite materials
JP3953649B2 (en) * 1998-07-17 2007-08-08 オリヱント化学工業株式会社 Organic-inorganic hybrid component gradient polymer material and method for producing the same
US6210570B1 (en) * 1998-08-21 2001-04-03 Agilent Technologies, Inc. Monolithic silica column
US6090477A (en) * 1998-09-11 2000-07-18 Ut-Battelle, Llc Gas storage carbon with enhanced thermal conductivity
DE19856000A1 (en) * 1998-12-04 2000-06-15 Bayer Ag Hybrid paint preparation
US6686035B2 (en) * 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
ATE350154T1 (en) * 1999-02-05 2007-01-15 Waters Investments Ltd METHOD FOR PRODUCING POROUS INORGANIC/ORGANIC HYBRID PARTICLES FOR CHROMATOGRAPHIC SEPARATION
JP4214203B2 (en) * 1999-05-18 2009-01-28 オリヱント化学工業株式会社 Organic-inorganic composite material and method for producing the same
US6368535B1 (en) * 1999-08-06 2002-04-09 Dow Corning Corporation Condensation reaction curable silsesquioxane resin composition and methods for the synthesis and cure thereof
US6649083B1 (en) * 1999-08-12 2003-11-18 Board Of Trustees Of Michigan State University Combined porous organic and inorganic oxide materials prepared by non-ionic surfactant templating route
US6998040B2 (en) * 2001-01-24 2006-02-14 University Of South Florida Sol-gel open tubular ODS columns with charged inner surface for capillary electrochromatography
US7250214B2 (en) * 2001-08-09 2007-07-31 Waters Investments Limited Porous inorganic/organic hybrid monolith materials for chromatographic separations and process for their preparation
DE10393599T5 (en) * 2002-10-30 2005-10-27 Waters Investments Ltd., New Castle Porous inorganic / organic homogeneous hybrid copolymeric materials for chromatographic separations and methods for their preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528167B2 (en) * 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface

Also Published As

Publication number Publication date
JP2007523331A (en) 2007-08-16
GB2427611A (en) 2007-01-03
GB0615709D0 (en) 2006-09-20
DE112005000269T5 (en) 2007-01-25
US20070215547A1 (en) 2007-09-20
WO2005079427A2 (en) 2005-09-01
US20140166581A1 (en) 2014-06-19

Similar Documents

Publication Publication Date Title
WO2005079427A3 (en) Porous hybrid monolith materials with organic groups removed from the surface
WO2004041398A3 (en) Porous inorganic/organic hybrid materials and preparation thereof
GB2433937B (en) Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation
WO2010027955A3 (en) Chromatography membranes, devices containing them, and methods of use thereof
WO2005089237A3 (en) Device and method for removing water and carbon dioxide from a gas mixture using pressure swing adsorption
EP2101999A4 (en) Porous carbon-heteroatom-silicon hybrid inorganic/organic materials for chromatographic separations and process for the preparation thereof
ATE464118T1 (en) POROUS HYBRID PARTICLES FOR CHROMATOGRAPHIC SEPARATION
WO2008137462A3 (en) Silver-based sorbents
EP1588995A4 (en) Pore-forming material for porous body, method for producing pore-forming material for porous body, method for producing porous body, porous body and honeycomb structure
DE602004024190D1 (en) GETRÄGERTE PORÖSE GELE COMPREHENSIVE COMPOSITE MATERIALS
WO2005052543A3 (en) Affinity domain for analyte sensor
ATE546421T1 (en) SMOKE FILTERS CONTAINING POROUS CARBON MATERIALS AND SMOKE ARTICLES IN WHICH SUCH FILTERS ARE INCORPORATED
WO2007092827A3 (en) Improved separation method
WO2012037101A3 (en) Chromatography membranes for the purification of chiral compounds
WO2002032589A3 (en) Porous layers and method for production thereof by means of spin-coating
WO2004105910A3 (en) Novel nanocomposites and their application as monolith columns
ZA200705086B (en) Catalytic materials and method for the preparation thereof
ATE503547T1 (en) FILTER MATERIAL
WO2005073711A3 (en) Chromatographic material for the absorption of proteins at physiological ionic strength
WO2006125564A3 (en) Elements for separating substances by distributing between a stationary and a mobile phase, and method for the production of a separating device
PL1729879T3 (en) Zeolithic adsorbing composition, method for the preparation and the use thereof for removing h2o and/or co2 and/or h2s contained in gas or liquid mixtures
AU2002302660A1 (en) Porous crystalline material (zeolite itq-21), the preparation method thereof and use of the same in the catalytic conversion of organic compounds
WO2006119048A3 (en) Affinity foam fractionation for collection and purification of materials
PL1634859T3 (en) Porous material and method for preparation thereof, and honeycomb structure
MXPA05008157A (en) Sintered adsorbents, preparation method thereof and use of same for the drying of organic compounds.

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 2006553361

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 1120050002691

Country of ref document: DE

WWE Wipo information: entry into national phase

Ref document number: 0615709

Country of ref document: GB

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
WWE Wipo information: entry into national phase

Ref document number: 10587598

Country of ref document: US

Ref document number: 2007215547

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 10587598

Country of ref document: US