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WO2005040789A3 - Diagnostics et traitements de maladies associees a un transporteur d'ion organique putatif okb1 (okb1) - Google Patents

Diagnostics et traitements de maladies associees a un transporteur d'ion organique putatif okb1 (okb1) Download PDF

Info

Publication number
WO2005040789A3
WO2005040789A3 PCT/EP2004/011013 EP2004011013W WO2005040789A3 WO 2005040789 A3 WO2005040789 A3 WO 2005040789A3 EP 2004011013 W EP2004011013 W EP 2004011013W WO 2005040789 A3 WO2005040789 A3 WO 2005040789A3
Authority
WO
WIPO (PCT)
Prior art keywords
diseases
okb1
therapeutics
diagnostics
diseases associated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2004/011013
Other languages
English (en)
Other versions
WO2005040789A2 (fr
Inventor
Stefan Golz
Ulf Brueggemeier
Andreas Geerts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Publication of WO2005040789A2 publication Critical patent/WO2005040789A2/fr
Publication of WO2005040789A3 publication Critical patent/WO2005040789A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne un OKB1 humain associé à des maladies cardiovasculaires, à des maladies gastroentérologiques, à des maladies métaboliques, à des maladies hématologiques, à des inflammations, à des troubles de la reproduction, à des cancers et à des maladies urologiques. L'invention concerne également des dosages destinés à identifier des composés utiles dans le traitement ou la prévention de maladies cardiovasculaires, de maladies gastroentérologiques, de maladies métaboliques, de maladies hématologiques, d'inflammations, de troubles de la reproduction, de cancers et de maladies urologiques. Cette invention concerne aussi des composés qui se lient et/ou activent ou inhibent l'activité de OKB1, ainsi que des compositions pharmaceutiques contenant ces composés.
PCT/EP2004/011013 2003-10-17 2004-10-02 Diagnostics et traitements de maladies associees a un transporteur d'ion organique putatif okb1 (okb1) Ceased WO2005040789A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03023810.9 2003-10-17
EP03023810 2003-10-17

Publications (2)

Publication Number Publication Date
WO2005040789A2 WO2005040789A2 (fr) 2005-05-06
WO2005040789A3 true WO2005040789A3 (fr) 2005-06-16

Family

ID=34486077

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/011013 Ceased WO2005040789A2 (fr) 2003-10-17 2004-10-02 Diagnostics et traitements de maladies associees a un transporteur d'ion organique putatif okb1 (okb1)

Country Status (1)

Country Link
WO (1) WO2005040789A2 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002062999A2 (fr) * 2000-12-29 2002-08-15 Curagen Corporation Proteines et acides nucleiques codant pour celles-ci

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002062999A2 (fr) * 2000-12-29 2002-08-15 Curagen Corporation Proteines et acides nucleiques codant pour celles-ci

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ENOMOTO ATSUSHI ET AL: "Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, no. 39, 27 September 2002 (2002-09-27), pages 36262 - 36271, XP002312925, ISSN: 0021-9258 *
ERALY SATISH A ET AL: "Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 297, no. 5, 11 October 2002 (2002-10-11), pages 1159 - 1166, XP002312926, ISSN: 0006-291X *
GONG SHIMEI ET AL: "Identification of OCT6 as a novel organic cation transporter preferentially expressed in hematopoietic cells and leukemias", EXPERIMENTAL HEMATOLOGY (NEW YORK), vol. 30, no. 10, October 2002 (2002-10-01), pages 1162 - 1169, XP002312927, ISSN: 0301-472X *

Also Published As

Publication number Publication date
WO2005040789A2 (fr) 2005-05-06

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