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WO2004069184A3 - Methods for treating, preventing and detecting helicobacter infection - Google Patents

Methods for treating, preventing and detecting helicobacter infection Download PDF

Info

Publication number
WO2004069184A3
WO2004069184A3 PCT/US2004/002867 US2004002867W WO2004069184A3 WO 2004069184 A3 WO2004069184 A3 WO 2004069184A3 US 2004002867 W US2004002867 W US 2004002867W WO 2004069184 A3 WO2004069184 A3 WO 2004069184A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
treating
preventing
helicobacter infection
detecting helicobacter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/002867
Other languages
French (fr)
Other versions
WO2004069184A2 (en
Inventor
John Ellis
George Krakowka
Kathyrn Eaton
Joel Flores
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cerebus Biologicals Inc
Original Assignee
Cerebus Biologicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA2514576A priority Critical patent/CA2514576C/en
Priority to MXPA05008252A priority patent/MXPA05008252A/en
Priority to BR0407207-3A priority patent/BRPI0407207A/en
Priority to DK04707401.8T priority patent/DK1599164T3/en
Priority to AU2004209985A priority patent/AU2004209985B2/en
Priority to EP04707401.8A priority patent/EP1599164B1/en
Priority to UAA200508503A priority patent/UA84284C2/en
Application filed by Cerebus Biologicals Inc filed Critical Cerebus Biologicals Inc
Publication of WO2004069184A2 publication Critical patent/WO2004069184A2/en
Anticipated expiration legal-status Critical
Priority to US11/196,722 priority patent/US20070026018A1/en
Priority to US11/360,366 priority patent/US7749512B2/en
Publication of WO2004069184A3 publication Critical patent/WO2004069184A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Compositions and methods for treating, preventing and diagnosing Hlicobacter infection are disclosed. The methods use proteins and/or nucleic acids derived from Helicobacter cerdo, a new pathogen isolated from swine.
PCT/US2004/002867 2003-02-03 2004-02-02 Methods for treating, preventing and detecting helicobacter infection Ceased WO2004069184A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
MXPA05008252A MXPA05008252A (en) 2003-02-03 2004-02-02 Methods for treating, preventing and detecting helicobacter infection.
BR0407207-3A BRPI0407207A (en) 2003-02-03 2004-02-02 Method to Treat, Prevent, and Diagnose a Heliocobacter Infection
DK04707401.8T DK1599164T3 (en) 2003-02-03 2004-02-02 METHODS OF TREATMENT, PREVENTION AND DETECTION OF HELICOBACTER INFECTION
AU2004209985A AU2004209985B2 (en) 2003-02-03 2004-02-02 Methods for treating, preventing and detecting Helicobacter infection
EP04707401.8A EP1599164B1 (en) 2003-02-03 2004-02-02 Methods for treating, preventing and detecting helicobacter infection
CA2514576A CA2514576C (en) 2003-02-03 2004-02-02 Methods for treating, preventing and diagnosing helicobacter infection
UAA200508503A UA84284C2 (en) 2003-02-03 2004-02-02 Methods for treating, preventing and detecting helicobacter infection
US11/196,722 US20070026018A1 (en) 2003-02-03 2005-08-03 Methods for treating, preventing and diagnosing Helicobacter infection
US11/360,366 US7749512B2 (en) 2003-02-03 2006-02-23 Porcine Helicobacter infection

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US44419003P 2003-02-03 2003-02-03
US60/444,190 2003-02-03
US51815603P 2003-11-07 2003-11-07
US60/518,156 2003-11-07

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/196,722 Continuation-In-Part US20070026018A1 (en) 2003-02-03 2005-08-03 Methods for treating, preventing and diagnosing Helicobacter infection

Publications (2)

Publication Number Publication Date
WO2004069184A2 WO2004069184A2 (en) 2004-08-19
WO2004069184A3 true WO2004069184A3 (en) 2006-12-21

Family

ID=32853359

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/002867 Ceased WO2004069184A2 (en) 2003-02-03 2004-02-02 Methods for treating, preventing and detecting helicobacter infection

Country Status (11)

Country Link
US (1) US20070026018A1 (en)
EP (1) EP1599164B1 (en)
AU (1) AU2004209985B2 (en)
BR (1) BRPI0407207A (en)
CA (1) CA2514576C (en)
DK (1) DK1599164T3 (en)
HU (1) HUE026171T2 (en)
MX (1) MXPA05008252A (en)
RU (1) RU2005127573A (en)
UA (1) UA84284C2 (en)
WO (1) WO2004069184A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060029617A1 (en) * 1997-10-03 2006-02-09 Charreyre Catherine E Porcine circovirus and Helicobacter combination vaccines and methods of use
EP1789094B1 (en) 2004-08-13 2014-12-10 MARSHALL, Barry J. Bacterial delivery system
US8029777B2 (en) 2004-08-13 2011-10-04 Marshall Barry J Helicobacter system and uses thereof
US7833707B2 (en) 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
UA95602C2 (en) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Pcv2 immunogenic compositions and methods of producing such compositions
SI1860951T1 (en) * 2005-02-23 2013-02-28 Cerebus Biologicals, Inc. Animal model for porcine helicobacter infection
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
ATE516817T1 (en) 2005-06-16 2011-08-15 Univ Gent VACCINES FOR IMMUNIZATION AGAINST HELICOBACTER
US7790143B2 (en) 2005-06-16 2010-09-07 Universiteit Gent Vaccines for immunization against helicobacter
DK3127551T3 (en) 2005-12-29 2020-10-12 Boehringer Ingelheim Animal Health Usa Inc PCV2 IMMUNOGENE COMPOSITION TO REDUCE CLINICAL SYMPTOMS IN PIGS
US20080226669A1 (en) 2005-12-29 2008-09-18 Boehringer Ingelheim Vetmedica, Inc. Multivalent pcv2 immunogenic compositions and methods of producing such compositions
EP1996228A4 (en) * 2006-03-17 2009-08-26 Cerebus Biolog Inc CAMPYLOBACTER VACCINES AND METHODS OF USE
US20080170996A1 (en) * 2006-07-28 2008-07-17 The Board Of Regents Of The University Of Texas System Compositions and Methods for Stimulation of Lung Innate Immunity
US20100129397A1 (en) 2006-12-11 2010-05-27 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
DK2094872T4 (en) 2006-12-15 2020-05-18 Boehringer Ingelheim Animal Health Usa Inc Treatment of anti-PCV2 antibody seropositive pigs with PCV2 antigen
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
US7829274B2 (en) 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
JP5613061B2 (en) 2008-01-23 2014-10-22 ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド PCV2 Mycoplasma hyopneumoniae immunogenic composition and method for producing said composition
US20110105383A1 (en) * 2008-09-10 2011-05-05 Magnus Hook Methods and compositions for stimulation of mammalian innate immune resistance to pathogens
KR101730351B1 (en) 2009-03-25 2017-04-28 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 Compositions for stimulation of mammalian innate immune resistance to pathogens
AR078253A1 (en) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed METHODS TO REDUCE ANTIVIRICAL ACTIVITY IN PCV-2 COMPOSITIONS AND PCV-2 COMPOSITIONS WITH BETTER IMMUNOGENICITY
JP6778104B2 (en) 2013-10-02 2020-10-28 ベーリンガー・インゲルハイム・アニマル・ヘルス・ユーエスエー・インコーポレイテッドＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ Ａｎｉｍａｌ Ｈｅａｌｔｈ Ｕｓａ Ｉｎｃ． PCV2 ORF2 protein variant and virus-like particles containing the above
US10286065B2 (en) 2014-09-19 2019-05-14 Board Of Regents, The University Of Texas System Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
US10828358B2 (en) 2015-12-14 2020-11-10 Technische Universität München Helicobacter pylori vaccines
EP3272354A1 (en) 2016-07-20 2018-01-24 Technische Universität München Agents and methods for the prevention or treatment of h. pylori infections
CN111793137A (en) * 2019-12-12 2020-10-20 南京蛋球球生物医学技术合伙企业(有限合伙) Hp tetravalent antigen and preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6130059A (en) * 1992-03-02 2000-10-10 Covacci; Antonello Helicobacter pylori proteins useful for vaccines and diagnostics
US20020107368A1 (en) * 2000-12-07 2002-08-08 Jing-Hui Tian Helicobacter proteins, gene sequences and uses thereof
US20020187161A1 (en) * 1997-01-24 2002-12-12 Cripps Allan William H. pylori antigens

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6130059A (en) * 1992-03-02 2000-10-10 Covacci; Antonello Helicobacter pylori proteins useful for vaccines and diagnostics
US20020187161A1 (en) * 1997-01-24 2002-12-12 Cripps Allan William H. pylori antigens
US20020107368A1 (en) * 2000-12-07 2002-08-08 Jing-Hui Tian Helicobacter proteins, gene sequences and uses thereof

Also Published As

Publication number Publication date
EP1599164B1 (en) 2015-04-08
MXPA05008252A (en) 2006-05-22
AU2004209985A1 (en) 2004-08-19
WO2004069184A2 (en) 2004-08-19
HUE026171T2 (en) 2016-05-30
CA2514576C (en) 2015-07-21
EP1599164A4 (en) 2007-08-01
CA2514576A1 (en) 2004-08-19
RU2005127573A (en) 2006-01-27
BRPI0407207A (en) 2006-01-24
AU2004209985B2 (en) 2008-09-18
US20070026018A1 (en) 2007-02-01
DK1599164T3 (en) 2015-04-27
UA84284C2 (en) 2008-10-10
EP1599164A2 (en) 2005-11-30

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