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WO2004061088A3 - Compositions and methods for inhibiting human immunodeficiency virus infection by down-regulating human cellular genes - Google Patents

Compositions and methods for inhibiting human immunodeficiency virus infection by down-regulating human cellular genes Download PDF

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Publication number
WO2004061088A3
WO2004061088A3 PCT/US2003/041790 US0341790W WO2004061088A3 WO 2004061088 A3 WO2004061088 A3 WO 2004061088A3 US 0341790 W US0341790 W US 0341790W WO 2004061088 A3 WO2004061088 A3 WO 2004061088A3
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WIPO (PCT)
Prior art keywords
immunodeficiency virus
methods
compositions
cellular genes
virus infection
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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PCT/US2003/041790
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French (fr)
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WO2004061088A2 (en
Inventor
Stephen J Dunn
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PPD Development LP
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PPD Development LP
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Filing date
Publication date
Application filed by PPD Development LP filed Critical PPD Development LP
Priority to AU2003300178A priority Critical patent/AU2003300178A1/en
Publication of WO2004061088A2 publication Critical patent/WO2004061088A2/en
Anticipated expiration legal-status Critical
Publication of WO2004061088A3 publication Critical patent/WO2004061088A3/en
Ceased legal-status Critical Current

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    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01012—Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (1.2.1.12)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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    • C12Y401/02—Aldehyde-lyases (4.1.2)
    • C12Y401/02013—Fructose-bisphosphate aldolase (4.1.2.13)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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  • Chemical & Material Sciences (AREA)
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  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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Abstract

The invention provides methods for identifying human cellular genes and their encoded for use as targets in the design of therapeutic agents for suppressing human immunodeficiency virus (HIV) infection. The invention also provides mehtods for identifying protective compounds that inhibit HIV infection. The invention further provides compounds for use in the treatment or prevention of HIV.
PCT/US2003/041790 2002-12-30 2003-12-30 Compositions and methods for inhibiting human immunodeficiency virus infection by down-regulating human cellular genes Ceased WO2004061088A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003300178A AU2003300178A1 (en) 2002-12-30 2003-12-30 Compositions and methods for inhibiting human immunodeficiency virus infection by down-regulating human cellular genes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43693602P 2002-12-30 2002-12-30
US60/436,936 2002-12-30

Publications (2)

Publication Number Publication Date
WO2004061088A2 WO2004061088A2 (en) 2004-07-22
WO2004061088A3 true WO2004061088A3 (en) 2006-03-23

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ID=32713107

Family Applications (1)

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PCT/US2003/041790 Ceased WO2004061088A2 (en) 2002-12-30 2003-12-30 Compositions and methods for inhibiting human immunodeficiency virus infection by down-regulating human cellular genes

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AU (1) AU2003300178A1 (en)
WO (1) WO2004061088A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2603452A1 (en) * 2005-04-04 2006-10-12 Julius-Maximillians-Universitat Wurzburg Tripeptides that down regulate the activity of plasma membrane transporters including sodium-d-glucose cotransporter sglt1
CN112336851A (en) 2014-01-13 2021-02-09 博格有限责任公司 Enolase 1(ENO1) compositions and uses thereof
WO2022272056A2 (en) * 2021-06-24 2022-12-29 University Of Utah Research Foundation Compositions and methods for treating pgm1 deficiency

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LEE K.H. ET AL: "Human alpha-Enolase From Endothelial Cells as a Target Antigen of Anti-Enothelial Cell Antibody in Behcet's Disease", ARTHRITIS AND RHEUMATISM, vol. 48, no. 7, July 2003 (2003-07-01), pages 2025 - 2035, XP002995517 *
SGADARI C. ET AL: "HIV protease inhibitors are potent anti-angiogenic molecule and promote regression of Kaposi sarcoma", NATURE MEDICINE, vol. 8, no. 3, March 2002 (2002-03-01), pages 225 - 232, XP002214286 *

Also Published As

Publication number Publication date
AU2003300178A1 (en) 2004-07-29
WO2004061088A2 (en) 2004-07-22
AU2003300178A8 (en) 2004-07-29

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