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WO2003039577A1 - Remedies for dry eye and diseases associated with dry eye - Google Patents

Remedies for dry eye and diseases associated with dry eye Download PDF

Info

Publication number
WO2003039577A1
WO2003039577A1 PCT/JP2002/011490 JP0211490W WO03039577A1 WO 2003039577 A1 WO2003039577 A1 WO 2003039577A1 JP 0211490 W JP0211490 W JP 0211490W WO 03039577 A1 WO03039577 A1 WO 03039577A1
Authority
WO
WIPO (PCT)
Prior art keywords
asn
dry eye
leu
ser
remedies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2002/011490
Other languages
English (en)
French (fr)
Inventor
Yoko Minagawa
Atsuko Fujii
Yukuo Yoshida
Satomi Onoue
Kazuhisa Kashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Itoham Foods Inc
Original Assignee
Senju Pharmaceutical Co Ltd
Itoham Foods Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd, Itoham Foods Inc filed Critical Senju Pharmaceutical Co Ltd
Priority to KR10-2004-7006854A priority Critical patent/KR20040065212A/ko
Priority to EP02775494A priority patent/EP1462112B1/en
Priority to DE60231649T priority patent/DE60231649D1/de
Priority to JP2003541868A priority patent/JP4249025B2/ja
Priority to US10/494,634 priority patent/US7459441B2/en
Publication of WO2003039577A1 publication Critical patent/WO2003039577A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PCT/JP2002/011490 2001-11-06 2002-11-05 Remedies for dry eye and diseases associated with dry eye Ceased WO2003039577A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
KR10-2004-7006854A KR20040065212A (ko) 2001-11-06 2002-11-05 건조안 및 건조안과 연관된 질환의 치료제
EP02775494A EP1462112B1 (en) 2001-11-06 2002-11-05 Remedies for dry eye and diseases associated with dry eye
DE60231649T DE60231649D1 (de) 2001-11-06 2002-11-05 Mittel zur behandlung von augentrockenheit und damit zusammenhängenden erkrankungen
JP2003541868A JP4249025B2 (ja) 2001-11-06 2002-11-05 ドライアイおよびドライアイを伴う疾病の治療剤
US10/494,634 US7459441B2 (en) 2001-11-06 2002-11-05 Remedies for dry eye and diseases associated with dry eye

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001-340355 2001-11-06
JP2001340355 2001-11-06

Publications (1)

Publication Number Publication Date
WO2003039577A1 true WO2003039577A1 (en) 2003-05-15

Family

ID=19154565

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/011490 Ceased WO2003039577A1 (en) 2001-11-06 2002-11-05 Remedies for dry eye and diseases associated with dry eye

Country Status (8)

Country Link
US (1) US7459441B2 (ja)
EP (1) EP1462112B1 (ja)
JP (1) JP4249025B2 (ja)
KR (1) KR20040065212A (ja)
CN (1) CN1315531C (ja)
AT (1) ATE425762T1 (ja)
DE (1) DE60231649D1 (ja)
WO (1) WO2003039577A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005102375A1 (ja) * 2004-04-23 2005-11-03 Senju Pharmaceutical Co., Ltd. Ｐａｃａｐおよびその誘導体を含有する角膜神経突起形成促進剤
EP1571155A4 (en) * 2002-11-27 2005-12-28 Itoham Foods Inc PEPTIDES AND MEDICAL COMPOSITIONS WITH THE SAME
JP2008537542A (ja) * 2005-03-07 2008-09-18 モンドビーオテッヒ ライセンシング オアト アーゲー アビプタジルのための処方物

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
ES2779992T3 (es) 2005-12-20 2020-08-21 Univ Duke Métodos y composiciones para suministrar agentes activos con propiedades farmacológicas potenciadas
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
US8025915B2 (en) * 2006-01-11 2011-09-27 Schott Ag Method of preparing a macromolecule deterrent surface on a pharmaceutical package
EP4074327A1 (en) 2008-06-27 2022-10-19 Duke University Therapeutic agents comprising elastin-like peptides
ES2624478T3 (es) 2009-08-14 2017-07-14 Phasebio Pharmaceuticals, Inc. Péptidos intestinales vasoactivos modificados
ES2669190T3 (es) 2011-06-06 2018-05-24 Phasebio Pharmaceuticals, Inc. Uso de péptidos intestinales vasoactivos modificados en el tratamiento de la hipertensión
ES2818824T3 (es) 2014-05-08 2021-04-14 Phasebio Pharmaceuticals Inc Composiciones que comprenden una proteína de fusión de VIP-ELP para su uso en el tratamiento de fibrosis quística
ES2822598T3 (es) 2015-02-09 2021-05-04 Phasebio Pharmaceuticals Inc Métodos y composiciones para tratar enfermedades y trastornos musculares
TWI619503B (zh) * 2015-12-14 2018-04-01 台灣基督長老教會馬偕醫療財團法人馬偕紀念醫院 短合成胜肽及其用途

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0204447A2 (en) * 1985-05-14 1986-12-10 Eye Research Institute Of Retina Foundation Pharmaceutical preparations which may be used for stimulating tear secretion
JPH05238950A (ja) * 1991-04-22 1993-09-17 Sanwa Kagaku Kenkyusho Co Ltd 易吸収性ｖｉｐ製剤
EP0796867A1 (en) * 1995-06-09 1997-09-24 Itoham Foods Inc. Peptide, bronchodilator and blood flow ameliorant
JP2001151799A (ja) * 1999-11-22 2001-06-05 Itoham Foods Inc 新規ペプチド及びそれを含有する消化管運動抑制剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08333276A (ja) * 1995-06-09 1996-12-17 Ito Ham Kk ペプチド及び気管支拡張剤

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0204447A2 (en) * 1985-05-14 1986-12-10 Eye Research Institute Of Retina Foundation Pharmaceutical preparations which may be used for stimulating tear secretion
JPH05238950A (ja) * 1991-04-22 1993-09-17 Sanwa Kagaku Kenkyusho Co Ltd 易吸収性ｖｉｐ製剤
EP0796867A1 (en) * 1995-06-09 1997-09-24 Itoham Foods Inc. Peptide, bronchodilator and blood flow ameliorant
JP2001151799A (ja) * 1999-11-22 2001-06-05 Itoham Foods Inc 新規ペプチド及びそれを含有する消化管運動抑制剤

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1571155A4 (en) * 2002-11-27 2005-12-28 Itoham Foods Inc PEPTIDES AND MEDICAL COMPOSITIONS WITH THE SAME
WO2005102375A1 (ja) * 2004-04-23 2005-11-03 Senju Pharmaceutical Co., Ltd. Ｐａｃａｐおよびその誘導体を含有する角膜神経突起形成促進剤
JPWO2005102375A1 (ja) * 2004-04-23 2008-03-06 千寿製薬株式会社 Ｐａｃａｐおよびその誘導体を含有する角膜神経突起形成促進剤
JP2008537542A (ja) * 2005-03-07 2008-09-18 モンドビーオテッヒ ライセンシング オアト アーゲー アビプタジルのための処方物
US8178489B2 (en) * 2005-03-07 2012-05-15 Mondobiotech Ag Formulation for aviptadil

Also Published As

Publication number Publication date
EP1462112B1 (en) 2009-03-18
KR20040065212A (ko) 2004-07-21
US7459441B2 (en) 2008-12-02
CN1612748A (zh) 2005-05-04
CN1315531C (zh) 2007-05-16
JPWO2003039577A1 (ja) 2005-02-24
EP1462112A4 (en) 2007-08-01
JP4249025B2 (ja) 2009-04-02
EP1462112A1 (en) 2004-09-29
ATE425762T1 (de) 2009-04-15
US20040259796A1 (en) 2004-12-23
DE60231649D1 (de) 2009-04-30

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