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WO2003039348A3 - Intracellular signaling molecules - Google Patents

Intracellular signaling molecules Download PDF

Info

Publication number
WO2003039348A3
WO2003039348A3 PCT/US2002/036151 US0236151W WO03039348A3 WO 2003039348 A3 WO2003039348 A3 WO 2003039348A3 US 0236151 W US0236151 W US 0236151W WO 03039348 A3 WO03039348 A3 WO 03039348A3
Authority
WO
WIPO (PCT)
Prior art keywords
intracellular signaling
signaling molecules
intsig
polynucleotides
agonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/036151
Other languages
French (fr)
Other versions
WO2003039348A2 (en
Inventor
Amy E Kable
Anita Swarnakar
Ann E Gorvad
April J A Hafalia
Brendan M Duggan
Bridget A Warren
Brooke M Emerling
Craig H Ison
Danniel B Nguyen
Erika A Lindquist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Priority to EP02786702A priority Critical patent/EP1504101A2/en
Priority to AU2002350174A priority patent/AU2002350174A1/en
Publication of WO2003039348A2 publication Critical patent/WO2003039348A2/en
Anticipated expiration legal-status Critical
Publication of WO2003039348A3 publication Critical patent/WO2003039348A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Various ernbodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
PCT/US2002/036151 2001-11-09 2002-11-07 Intracellular signaling molecules Ceased WO2003039348A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02786702A EP1504101A2 (en) 2001-11-09 2002-11-07 Intracellular signaling molecules
AU2002350174A AU2002350174A1 (en) 2001-11-09 2002-11-07 Intracellular signaling molecules

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US34447201P 2001-11-09 2001-11-09
US60/344,472 2001-11-09
US33455801P 2001-11-30 2001-11-30
US60/334,558 2001-11-30
US34029601P 2001-12-14 2001-12-14
US60/340,296 2001-12-14
US34355701P 2001-12-21 2001-12-21
US60/343,557 2001-12-21
US35042002P 2002-01-18 2002-01-18
US60/350,420 2002-01-18
US35192702P 2002-01-25 2002-01-25
US60/351,927 2002-01-25

Publications (2)

Publication Number Publication Date
WO2003039348A2 WO2003039348A2 (en) 2003-05-15
WO2003039348A3 true WO2003039348A3 (en) 2004-12-02

Family

ID=27559760

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/036151 Ceased WO2003039348A2 (en) 2001-11-09 2002-11-07 Intracellular signaling molecules

Country Status (3)

Country Link
EP (1) EP1504101A2 (en)
AU (1) AU2002350174A1 (en)
WO (1) WO2003039348A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080274954A1 (en) * 2004-04-15 2008-11-06 Osamu Ohara Gene Encoding a Guanine Nucleotide Exchange Factor and Its Gene Product
JP2006212003A (en) * 2005-02-07 2006-08-17 Univ Of Tokyo Tumor suppressor gene product-related protein
AU2011305655B2 (en) 2010-09-22 2015-11-05 Alios Biopharma, Inc. Substituted nucleotide analogs
WO2013096680A1 (en) 2011-12-22 2013-06-27 Alios Biopharma, Inc. Substituted phosphorothioate nucleotide analogs
WO2013142157A1 (en) 2012-03-22 2013-09-26 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BARAN C.P. ET AL: "The Role of ROS and RNS in Regulating Life and Death of Blood Monocytes", CURRENT PHARMACEUTICAL DESIGN, vol. 10, no. 8, 2004, pages 855 - 866, XP002981281 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug

Also Published As

Publication number Publication date
WO2003039348A2 (en) 2003-05-15
EP1504101A2 (en) 2005-02-09
AU2002350174A1 (en) 2003-05-19

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