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WO2003018037A3 - Regulation method of cell growth - Google Patents

Regulation method of cell growth Download PDF

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Publication number
WO2003018037A3
WO2003018037A3 PCT/IB2002/003656 IB0203656W WO03018037A3 WO 2003018037 A3 WO2003018037 A3 WO 2003018037A3 IB 0203656 W IB0203656 W IB 0203656W WO 03018037 A3 WO03018037 A3 WO 03018037A3
Authority
WO
WIPO (PCT)
Prior art keywords
rate
regulating
growth
cell growth
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2002/003656
Other languages
French (fr)
Other versions
WO2003018037A2 (en
Inventor
Stephen Cohen
Aurelio Teleman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Europaisches Laboratorium fuer Molekularbiologie EMBL
Original Assignee
Europaisches Laboratorium fuer Molekularbiologie EMBL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0119446.3A external-priority patent/GB0119446D0/en
Priority claimed from GBGB0124259.3A external-priority patent/GB0124259D0/en
Application filed by Europaisches Laboratorium fuer Molekularbiologie EMBL filed Critical Europaisches Laboratorium fuer Molekularbiologie EMBL
Priority to AU2002330693A priority Critical patent/AU2002330693A1/en
Publication of WO2003018037A2 publication Critical patent/WO2003018037A2/en
Publication of WO2003018037A3 publication Critical patent/WO2003018037A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to methods of regulating the rate of growth of cells, tissues and organisms by regulating the rate of cell mass accumulation and the rate of cell cycle progression in a co-ordinated manner. In particular, the invention relates to methods of regulating the rate of growth of cells, tissues and organisms by modulating the level and the activity of specific proteins. The invention also relates to the use of these proteins, for example, in the treatment of diseases and conditions associated with an aberrant rate of cell growth.
PCT/IB2002/003656 2001-08-09 2002-08-08 Regulation method of cell growth Ceased WO2003018037A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002330693A AU2002330693A1 (en) 2001-08-09 2002-08-08 Regulation method of cell growth

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0119446.3 2001-08-09
GBGB0119446.3A GB0119446D0 (en) 2001-08-09 2001-08-09 Binding proteins
GB0124259.3 2001-10-09
GBGB0124259.3A GB0124259D0 (en) 2001-10-09 2001-10-09 Regulation method

Publications (2)

Publication Number Publication Date
WO2003018037A2 WO2003018037A2 (en) 2003-03-06
WO2003018037A3 true WO2003018037A3 (en) 2003-10-02

Family

ID=26246421

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2002/003656 Ceased WO2003018037A2 (en) 2001-08-09 2002-08-08 Regulation method of cell growth

Country Status (2)

Country Link
AU (1) AU2002330693A1 (en)
WO (1) WO2003018037A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1754487A1 (en) * 2005-07-27 2007-02-21 The European Molecular Biology Laboratory Modulators of the Melted protein and uses thereof

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 January 1998 (1998-01-01), "Hypothetical 93.1 kDA protein", XP002235338, retrieved from EBI Database accession no. O17237 *
DATABASE EMBL [online] 1 May 2000 (2000-05-01), ADAMS M ET AL: "Melt protein", XP002235337, retrieved from EBI Database accession no. Q9VS24 *
DATABASE EMBL [online] 12 December 1999 (1999-12-12), PROKOPENKO S ET AL: "Drosophila melnogaster Melted (melt) mRNA, partial cds.", XP002235336, retrieved from EBI Database accession no. AF205831 *
DATABASE EMBL [online] 15 May 2001 (2001-05-15), ISOGAI T ET AL: "Homo sapiens cDNA FLJ14719 fis, clone NT2RP3001457, weakly similar to Drosophila melanogaster Melted mRNA", XP002235334, retrieved from EBI Database accession no. AK027625 *
DATABASE EMBL [online] 7 February 2001 (2001-02-07), OHARA O ET AL: "Homo sapiens mRNA for KIAA1692", XP002235333, retrieved from EBI Database accession no. AB051479 *
DATABASE EMBL [online] 7 February 2001 (2001-02-07), OTA T ET AL: "Human cDNA sequence SEQ ID No:11990", XP002235335, retrieved from EBI Database accession no. AAH14484 *
NAGASE T ET AL: "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro", DNA RESEARCH, vol. 6, 1999, pages 337 - 345, XP000865804 *
PROKOPENKO S ET AL: "Mutations affecting the development of the peripheral nervous system in Drosophila: A molecular screen for novel proteins", GENETICS, vol. 156, December 2000 (2000-12-01), pages 1691 - 1715 *
STOCKER HUGO ET AL: "Genetic control of cell size.", CURRENT OPINION IN GENETICS & DEVELOPMENT, vol. 10, no. 5, October 2000 (2000-10-01), pages 529 - 535, XP002235332, ISSN: 0959-437X *

Also Published As

Publication number Publication date
AU2002330693A1 (en) 2003-03-10
WO2003018037A2 (en) 2003-03-06

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