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WO2003013239A3 - Verfahren zur devitalisierung natürlicher organe und/oder zur bereitstellung extrazellulärer matrices zum 'tissue-engineering' - Google Patents

Verfahren zur devitalisierung natürlicher organe und/oder zur bereitstellung extrazellulärer matrices zum 'tissue-engineering' Download PDF

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Publication number
WO2003013239A3
WO2003013239A3 PCT/EP2002/008781 EP0208781W WO03013239A3 WO 2003013239 A3 WO2003013239 A3 WO 2003013239A3 EP 0208781 W EP0208781 W EP 0208781W WO 03013239 A3 WO03013239 A3 WO 03013239A3
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WO
WIPO (PCT)
Prior art keywords
organs
devitalisation
preparation
tissue engineering
natural
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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PCT/EP2002/008781
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English (en)
French (fr)
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WO2003013239A2 (de
Inventor
Peter Lamm
Gerd Juchem
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Individual
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Application filed by Individual filed Critical Individual
Priority to US10/485,947 priority Critical patent/US20050009000A1/en
Priority to AU2002340807A priority patent/AU2002340807A1/en
Priority to EP02774502A priority patent/EP1414295A2/de
Publication of WO2003013239A2 publication Critical patent/WO2003013239A2/de
Publication of WO2003013239A3 publication Critical patent/WO2003013239A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A01N1/143—Apparatus for organ perfusion
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Die Erfindung betrifft Verfahren zur Devitalisierung und Konservierung menschlicher und Tierischer Organe und Gewebe, bevorzugt jedoch natürlicher Hohlorgane und deren sämtlicher Bestandteile, insbesondere von Blutgefässen und Herzklappen. Des weiteren betrifft die Erfindung Verfahren zur Herstellung von Matrices für den Teil- und Neuaufbau von Organen und Geweben. Darüber hinaus betrifft die Erfindung Organe und Gewebe, insbesondere natürliche und künstliche Hohlorgane, die nach den erfindungsgemässen Verfahren erhältlich sind. Weiterhin betrifft die Erfindung den klinischen Einsatz und die Verwendung der hergestellten Organe und Gewebe in der Medizin und Veterinärmedizin, vorzugsweise in der Herz- und Gefässchirurgie. Weiterhin betrifft die Erfindung neue Kulturmedien.
PCT/EP2002/008781 2001-08-06 2002-08-06 Verfahren zur devitalisierung natürlicher organe und/oder zur bereitstellung extrazellulärer matrices zum 'tissue-engineering' Ceased WO2003013239A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/485,947 US20050009000A1 (en) 2001-08-06 2002-08-06 Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering
AU2002340807A AU2002340807A1 (en) 2001-08-06 2002-08-06 Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering
EP02774502A EP1414295A2 (de) 2001-08-06 2002-08-06 Verfahren zur devitalisierung natürlicher organe und/oder zur bereitstellung extrazellulärer matrices zum "tissue-engineering"

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10138564.1 2001-08-06
DE10138564A DE10138564B4 (de) 2001-08-06 2001-08-06 Verfahren zur Devitalisierung natürlicher Organe und/oder zur Bereitstellung extrazellulärer Matrices zum "Tissue-Engineering"

Publications (2)

Publication Number Publication Date
WO2003013239A2 WO2003013239A2 (de) 2003-02-20
WO2003013239A3 true WO2003013239A3 (de) 2003-10-02

Family

ID=7694560

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/008781 Ceased WO2003013239A2 (de) 2001-08-06 2002-08-06 Verfahren zur devitalisierung natürlicher organe und/oder zur bereitstellung extrazellulärer matrices zum 'tissue-engineering'

Country Status (5)

Country Link
US (1) US20050009000A1 (de)
EP (1) EP1414295A2 (de)
AU (1) AU2002340807A1 (de)
DE (1) DE10138564B4 (de)
WO (1) WO2003013239A2 (de)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE45130E1 (en) 2000-02-28 2014-09-09 Jenavalve Technology Gmbh Device for fastening and anchoring cardiac valve prostheses
US8834561B2 (en) 2005-10-28 2014-09-16 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US9138315B2 (en) 2007-04-13 2015-09-22 Jenavalve Technology Gmbh Medical device for treating a heart valve insufficiency or stenosis
US9168130B2 (en) 2008-02-26 2015-10-27 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9265631B2 (en) 2008-02-26 2016-02-23 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9295551B2 (en) 2007-04-13 2016-03-29 Jenavalve Technology Gmbh Methods of implanting an endoprosthesis
US9339386B2 (en) 2007-04-13 2016-05-17 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficency
US9439759B2 (en) 2008-02-26 2016-09-13 Jenavalve Technology, Inc. Endoprosthesis for implantation in the heart of a patient
US9510947B2 (en) 2011-10-21 2016-12-06 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient
US9597182B2 (en) 2010-05-20 2017-03-21 Jenavalve Technology Inc. Catheter system for introducing an expandable stent into the body of a patient

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DE10010073B4 (de) 2000-02-28 2005-12-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verankerung für implantierbare Herzklappenprothesen
US7968329B2 (en) * 2000-10-06 2011-06-28 Michael Dancu Method of conditioning a hybrid synthetic tubular structure to yield a functional human hybrid coronary bypass graft
US7964387B2 (en) * 2000-10-06 2011-06-21 Michael Dancu Method of conditioning a hybrid synthetic tubular structure to yield a functional human hybrid hemodialysis access graft
FR2828263B1 (fr) 2001-08-03 2007-05-11 Philipp Bonhoeffer Dispositif d'implantation d'un implant et procede d'implantation du dispositif
DE10326764A1 (de) * 2003-06-13 2004-12-30 Biotest Ag Endothel-protektive Perfusionslösung, eine Apparatur und Verfahren zur Konservierung des Endothels in isolierten Hohlorganen und biologischen Gefäßen
DE102005003632A1 (de) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Katheter für die transvaskuläre Implantation von Herzklappenprothesen
DE102005052628B4 (de) 2005-11-04 2014-06-05 Jenavalve Technology Inc. Selbstexpandierendes, flexibles Drahtgeflecht mit integrierter Klappenprothese für den transvaskulären Herzklappenersatz und ein System mit einer solchen Vorrichtung und einem Einführkatheter
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US20100260815A1 (en) * 2007-06-22 2010-10-14 Circle Biologics , LLC Fluid concentrator, autologous concentrated body fluids, and uses thereof
US8398704B2 (en) 2008-02-26 2013-03-19 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
WO2011104269A1 (en) 2008-02-26 2011-09-01 Jenavalve Technology Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US8468667B2 (en) * 2009-05-15 2013-06-25 Jenavalve Technology, Inc. Device for compressing a stent
JP2013524784A (ja) * 2010-04-08 2013-06-20 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 血小板の保存のためのゼオドレーション法
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US11278406B2 (en) 2010-05-20 2022-03-22 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
US9744031B2 (en) 2010-05-25 2017-08-29 Jenavalve Technology, Inc. Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent
US8834928B1 (en) 2011-05-16 2014-09-16 Musculoskeletal Transplant Foundation Tissue-derived tissugenic implants, and methods of fabricating and using same
CN104470471B (zh) 2012-05-16 2017-05-31 耶拿阀门科技有限责任公司 用于引入可扩张的心脏瓣膜假体的导管递送系统和用于治疗心脏瓣膜缺陷的医疗设备
US20150037436A1 (en) 2013-07-30 2015-02-05 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US9867694B2 (en) 2013-08-30 2018-01-16 Jenavalve Technology Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
EP3730094B1 (de) 2015-03-20 2024-04-24 JenaValve Technology, Inc. Herzklappenprothesenabgabesystem
EP4403138A3 (de) 2015-05-01 2024-10-09 JenaValve Technology, Inc. Vorrichtung und verfahren mit reduzierter herzschrittmacherrate bei herzklappenersatz
WO2016187413A1 (en) 2015-05-21 2016-11-24 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
WO2017011653A1 (en) * 2015-07-15 2017-01-19 The University Of Florida Research Foundation, Inc. Tissue decellularization methods
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
CN105638641B (zh) * 2016-03-16 2018-05-29 麦重伟 葡甘露胶在标本保存中的应用及其使用方法
US11065138B2 (en) 2016-05-13 2021-07-20 Jenavalve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
WO2018138658A1 (en) 2017-01-27 2018-08-02 Jenavalve Technology, Inc. Heart valve mimicry
US11369107B2 (en) * 2019-05-09 2022-06-28 Restoration Biologies LLC Live tissue storage solution
WO2024102411A1 (en) 2022-11-09 2024-05-16 Jenavalve Technology, Inc. Catheter system for sequential deployment of an expandable implant

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Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE45130E1 (en) 2000-02-28 2014-09-09 Jenavalve Technology Gmbh Device for fastening and anchoring cardiac valve prostheses
USRE45790E1 (en) 2005-10-28 2015-11-03 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US8834561B2 (en) 2005-10-28 2014-09-16 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US9402717B2 (en) 2005-10-28 2016-08-02 Jenavalve Technology, Inc. Device for the implantation and fixation of prosthetic valves
US9044320B2 (en) 2005-10-28 2015-06-02 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
USRE45962E1 (en) 2005-10-28 2016-04-05 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US9295551B2 (en) 2007-04-13 2016-03-29 Jenavalve Technology Gmbh Methods of implanting an endoprosthesis
US9138315B2 (en) 2007-04-13 2015-09-22 Jenavalve Technology Gmbh Medical device for treating a heart valve insufficiency or stenosis
US9339386B2 (en) 2007-04-13 2016-05-17 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficency
US9445896B2 (en) 2007-04-13 2016-09-20 Jenavalve Technology, Inc. Methods for treating a heart valve insufficiency or stenosis
US9265631B2 (en) 2008-02-26 2016-02-23 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9168130B2 (en) 2008-02-26 2015-10-27 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US9439759B2 (en) 2008-02-26 2016-09-13 Jenavalve Technology, Inc. Endoprosthesis for implantation in the heart of a patient
US9597182B2 (en) 2010-05-20 2017-03-21 Jenavalve Technology Inc. Catheter system for introducing an expandable stent into the body of a patient
US9510947B2 (en) 2011-10-21 2016-12-06 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient

Also Published As

Publication number Publication date
WO2003013239A2 (de) 2003-02-20
DE10138564B4 (de) 2007-07-12
AU2002340807A1 (en) 2003-02-24
US20050009000A1 (en) 2005-01-13
EP1414295A2 (de) 2004-05-06
DE10138564A1 (de) 2003-02-27

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