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WO2003009100A3 - Methodes, appareil et programmes informatiques de verification de l'integrite d'une sonde - Google Patents

Methodes, appareil et programmes informatiques de verification de l'integrite d'une sonde Download PDF

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Publication number
WO2003009100A3
WO2003009100A3 PCT/US2002/022728 US0222728W WO03009100A3 WO 2003009100 A3 WO2003009100 A3 WO 2003009100A3 US 0222728 W US0222728 W US 0222728W WO 03009100 A3 WO03009100 A3 WO 03009100A3
Authority
WO
WIPO (PCT)
Prior art keywords
probe
apparatuses
computer programs
methods
verifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/022728
Other languages
English (en)
Other versions
WO2003009100A2 (fr
Inventor
Stanley H Sakai
William Mcmillan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cepheid
Original Assignee
Cepheid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cepheid filed Critical Cepheid
Priority to EP02752409A priority Critical patent/EP1415152B1/fr
Priority to AT02752409T priority patent/ATE508360T1/de
Priority to AU2002355109A priority patent/AU2002355109B2/en
Priority to CA2453366A priority patent/CA2453366C/fr
Priority to JP2003514378A priority patent/JP4392240B2/ja
Priority to DE60239940T priority patent/DE60239940D1/de
Publication of WO2003009100A2 publication Critical patent/WO2003009100A2/fr
Publication of WO2003009100A3 publication Critical patent/WO2003009100A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medical Informatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Tests Of Electronic Circuits (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)

Abstract

La présente invention concerne des méthodes, des appareils et des programmes informatiques de vérification de l'intégrité d'une sonde par comparaison de la valeur du signal d'une sonde à une valeur seuil. L'invention concerne également des méthodes, des appareils et des programmes informatiques de normalisation de la valeur du signal d'une sonde et de détection d'un acide nucléique cible dans un échantillon.
PCT/US2002/022728 2001-07-16 2002-07-16 Methodes, appareil et programmes informatiques de verification de l'integrite d'une sonde Ceased WO2003009100A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP02752409A EP1415152B1 (fr) 2001-07-16 2002-07-16 Methodes, appareil et programmes informatiques de verification de l'integrite d'une sonde
AT02752409T ATE508360T1 (de) 2001-07-16 2002-07-16 Verfahren, vorrichtungen und computerprogramme zum verifizieren der integrität einer sonde
AU2002355109A AU2002355109B2 (en) 2001-07-16 2002-07-16 Methods, apparatuses, and computer programs for verifying the integrity of a probe
CA2453366A CA2453366C (fr) 2001-07-16 2002-07-16 Methodes, appareil et programmes informatiques de verification de l'integrite d'une sonde
JP2003514378A JP4392240B2 (ja) 2001-07-16 2002-07-16 プローブの完全性を検証するための方法、装置、およびコンピュータプログラム
DE60239940T DE60239940D1 (de) 2001-07-16 2002-07-16 Verfahren, vorrichtungen und computerprogramme zum verifizieren der integrität einer sonde

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/906,897 US7226732B2 (en) 2001-07-16 2001-07-16 Methods, apparatus, and computer programs for verifying the integrity of a probe
US09/906,897 2001-07-16

Publications (2)

Publication Number Publication Date
WO2003009100A2 WO2003009100A2 (fr) 2003-01-30
WO2003009100A3 true WO2003009100A3 (fr) 2003-11-27

Family

ID=25423168

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/022728 Ceased WO2003009100A2 (fr) 2001-07-16 2002-07-16 Methodes, appareil et programmes informatiques de verification de l'integrite d'une sonde

Country Status (9)

Country Link
US (3) US7226732B2 (fr)
EP (1) EP1415152B1 (fr)
JP (4) JP4392240B2 (fr)
AT (1) ATE508360T1 (fr)
AU (1) AU2002355109B2 (fr)
CA (1) CA2453366C (fr)
DE (1) DE60239940D1 (fr)
ES (1) ES2365699T3 (fr)
WO (1) WO2003009100A2 (fr)

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US7226732B2 (en) * 2001-07-16 2007-06-05 Cepheid Methods, apparatus, and computer programs for verifying the integrity of a probe
US20080193961A1 (en) * 2004-09-29 2008-08-14 Easley Christopher J Localized Control of Thermal Properties on Microdevices and Applications Thereof
WO2006044458A2 (fr) 2004-10-13 2006-04-27 University Of Virginia Patent Foundation ACTIONNEMENT ELECTROSTATIQUE DESTINE A LA REGULATION D'UN FLUX DANS DES SYSTEMES D'ANALYSE MICRO-TOTALE (µ-TAS) ET PROCEDE CORRESPONDANT
US8084260B2 (en) * 2004-11-24 2011-12-27 Applied Biosystems, Llc Spectral calibration method and system for multiple instruments
US20080277387A1 (en) * 2004-12-22 2008-11-13 Landers James P Use of Microwaves For Thermal and Non-Thermal Applications in Micro and Nanoscale Devices
US8343755B2 (en) * 2005-08-01 2013-01-01 University Of Virginia Patent Foundation Microdevices for chemical sensing and chemical actuation
WO2007024829A2 (fr) 2005-08-23 2007-03-01 University Of Virginia Patent Foundation Composants passifs pour profilage d'un debit microfluide, et procede associe
CA2624914A1 (fr) * 2005-10-04 2007-04-12 University Of Virginia Patent Foundation Piegeage acoustique fonde sur une micropuce ou capture de cellules pour une analyse medico-legale et methodes associees
WO2007047336A2 (fr) * 2005-10-12 2007-04-26 University Of Virginia Patent Foundation Systemes d'analyse microfluidique integres
WO2007103430A2 (fr) * 2006-03-06 2007-09-13 Applera Corporation Procédé et système de production d'une topologie de porte-échantillons destinés à la validation
WO2007114338A1 (fr) 2006-03-31 2007-10-11 Takeda Pharmaceutical Company Limited Inhibiteur de secretion d'acide
JP2008180677A (ja) * 2007-01-26 2008-08-07 Konica Minolta Medical & Graphic Inc マイクロチップ検査システム、マイクロチップ検査装置及びプログラム
FR2922897B1 (fr) * 2007-10-25 2009-11-27 Bio Rad Pasteur Mesure d'une population d'acides nucleiques,en particulier par pcr en temps reel.
US10388403B2 (en) 2010-01-19 2019-08-20 Verinata Health, Inc. Analyzing copy number variation in the detection of cancer
WO2011090556A1 (fr) 2010-01-19 2011-07-28 Verinata Health, Inc. Procédés pour déterminer une fraction d'acide nucléique fœtal dans des échantillons maternels
US9260745B2 (en) 2010-01-19 2016-02-16 Verinata Health, Inc. Detecting and classifying copy number variation
CA2786564A1 (fr) 2010-01-19 2011-07-28 Verinata Health, Inc. Identification de cellules polymorphes dans des melanges d'adn genomique par sequencage du genome entier
US9323888B2 (en) 2010-01-19 2016-04-26 Verinata Health, Inc. Detecting and classifying copy number variation
CA2786565C (fr) 2010-01-19 2017-04-25 Verinata Health, Inc. Procedes de detection definis par des partitions
CA2786544C (fr) 2010-01-19 2020-11-10 Verinata Health, Inc. Methodes de preparation de bibliotheque ameliorees destinees a la detection d'aneuploidie foetale
US20120100548A1 (en) * 2010-10-26 2012-04-26 Verinata Health, Inc. Method for determining copy number variations
CN102985566B (zh) 2010-06-30 2015-06-17 简.探针公司 使用分析物和过程控制信号的单次读取确定而鉴定含分析物的样品的方法和设备
CA2832468C (fr) 2011-04-12 2023-10-31 Verinata Health, Inc. Resolution de fractions du genome a l'aide des nombres de polymorphismes
US9411937B2 (en) 2011-04-15 2016-08-09 Verinata Health, Inc. Detecting and classifying copy number variation
WO2014093360A1 (fr) 2012-12-10 2014-06-19 Landers James P Filtrage à base de fréquence d'un actionnement mécanique utilisant un dispositif fluidique
GB201403076D0 (en) * 2014-02-21 2014-04-09 ALERE TECHNOLOGIES GmbH Methods for detecting multiple nucleic acids in a sample
ES2896198T3 (es) * 2014-10-10 2022-02-24 Univ Rutgers Cebadores y sondas de reacción en cadena de polimerasa para Mycobacterium tuberculosis
US20190093155A1 (en) * 2017-05-25 2019-03-28 Roche Molecular Systems, Inc. Multiplex Nucleic Acid Amplification Assay
US11667945B2 (en) 2017-08-28 2023-06-06 Shizuoka Prefecture Public University Corporation Detection method and detection probe for colibactin and colibactin-producing bacteria

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Publication number Priority date Publication date Assignee Title
US6312929B1 (en) * 2000-12-22 2001-11-06 Cepheid Compositions and methods enabling a totally internally controlled amplification reaction

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Also Published As

Publication number Publication date
US20030064368A1 (en) 2003-04-03
JP2013188228A (ja) 2013-09-26
AU2002355109B2 (en) 2007-05-31
JP4392240B2 (ja) 2009-12-24
US9206470B2 (en) 2015-12-08
DE60239940D1 (de) 2011-06-16
EP1415152A4 (fr) 2005-03-23
JP2016154550A (ja) 2016-09-01
JP2005515404A (ja) 2005-05-26
US9464317B2 (en) 2016-10-11
US20070259362A1 (en) 2007-11-08
ES2365699T3 (es) 2011-10-10
CA2453366C (fr) 2013-04-16
EP1415152A2 (fr) 2004-05-06
WO2003009100A2 (fr) 2003-01-30
JP6434930B2 (ja) 2018-12-05
US7226732B2 (en) 2007-06-05
JP5955274B2 (ja) 2016-07-20
CA2453366A1 (fr) 2003-01-30
ATE508360T1 (de) 2011-05-15
US20080227090A1 (en) 2008-09-18
JP2009165475A (ja) 2009-07-30
EP1415152B1 (fr) 2011-05-04
JP5328412B2 (ja) 2013-10-30

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