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WO2003000859A3 - G-protein coupled receptors - Google Patents

G-protein coupled receptors Download PDF

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Publication number
WO2003000859A3
WO2003000859A3 PCT/US2002/020036 US0220036W WO03000859A3 WO 2003000859 A3 WO2003000859 A3 WO 2003000859A3 US 0220036 W US0220036 W US 0220036W WO 03000859 A3 WO03000859 A3 WO 03000859A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein coupled
coupled receptors
gcrec
polynucleotides
agonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/020036
Other languages
French (fr)
Other versions
WO2003000859A2 (en
Inventor
Mariah R Baughn
Narinder K Chawla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Priority to CA002450925A priority Critical patent/CA2450925A1/en
Priority to JP2003507246A priority patent/JP2005500037A/en
Priority to AU2002316366A priority patent/AU2002316366A1/en
Priority to EP02746660A priority patent/EP1551872A2/en
Publication of WO2003000859A2 publication Critical patent/WO2003000859A2/en
Anticipated expiration legal-status Critical
Publication of WO2003000859A3 publication Critical patent/WO2003000859A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Various embodiments of the invention provide human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
PCT/US2002/020036 2001-06-22 2002-06-20 G-protein coupled receptors Ceased WO2003000859A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002450925A CA2450925A1 (en) 2001-06-22 2002-06-20 G-protein coupled receptors
JP2003507246A JP2005500037A (en) 2001-06-22 2002-06-20 G protein coupled receptor
AU2002316366A AU2002316366A1 (en) 2001-06-22 2002-06-20 G-protein coupled receptors
EP02746660A EP1551872A2 (en) 2001-06-22 2002-06-20 G-protein coupled receptors

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US30049401P 2001-06-22 2001-06-22
US60/300,494 2001-06-22
US30532601P 2001-07-13 2001-07-13
US60/305,326 2001-07-13
US30816501P 2001-07-27 2001-07-27
US60/308,165 2001-07-27
US31011501P 2001-08-03 2001-08-03
US60/310,115 2001-08-03
US31141301P 2001-08-10 2001-08-10
US60/311,413 2001-08-10
US31467901P 2001-08-24 2001-08-24
US60/314,679 2001-08-24

Publications (2)

Publication Number Publication Date
WO2003000859A2 WO2003000859A2 (en) 2003-01-03
WO2003000859A3 true WO2003000859A3 (en) 2004-01-08

Family

ID=27559646

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/020036 Ceased WO2003000859A2 (en) 2001-06-22 2002-06-20 G-protein coupled receptors

Country Status (5)

Country Link
EP (1) EP1551872A2 (en)
JP (1) JP2005500037A (en)
AU (1) AU2002316366A1 (en)
CA (1) CA2450925A1 (en)
WO (1) WO2003000859A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
JP6395426B2 (en) * 2014-04-14 2018-09-26 花王株式会社 Search method for butyl acrylate odor suppressor
EP3997459A1 (en) * 2019-10-04 2022-05-18 Firmenich SA Method for attributing olfactory tonalities to olfactory receptor activation and methods for identifying compounds having the attributed tonalities

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001027158A2 (en) * 1999-10-08 2001-04-19 Digiscents Olfactory receptor sequences
US20020132273A1 (en) * 2000-06-22 2002-09-19 Senomyx, Inc. Receptor fingerprinting, sensory perception, and biosensors of chemical sensants

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001027158A2 (en) * 1999-10-08 2001-04-19 Digiscents Olfactory receptor sequences
US20020132273A1 (en) * 2000-06-22 2002-09-19 Senomyx, Inc. Receptor fingerprinting, sensory perception, and biosensors of chemical sensants

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZHANG ET AL.: "The olfactory receptor gene superfamily of the mouse", NATURE NEUROSCIENCE, vol. 5, no. 2, February 2002 (2002-02-01), pages 124 - 133, XP002969023 *

Also Published As

Publication number Publication date
JP2005500037A (en) 2005-01-06
AU2002316366A1 (en) 2003-01-08
CA2450925A1 (en) 2003-01-03
WO2003000859A2 (en) 2003-01-03
EP1551872A2 (en) 2005-07-13

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