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WO2003000842A3 - Nouvelles proteines et acides nucleiques codant pour de telles proteines - Google Patents

Nouvelles proteines et acides nucleiques codant pour de telles proteines Download PDF

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Publication number
WO2003000842A3
WO2003000842A3 PCT/US2002/017443 US0217443W WO03000842A3 WO 2003000842 A3 WO2003000842 A3 WO 2003000842A3 US 0217443 W US0217443 W US 0217443W WO 03000842 A3 WO03000842 A3 WO 03000842A3
Authority
WO
WIPO (PCT)
Prior art keywords
small molecule
molecule target
nucleic acids
acids encoding
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/017443
Other languages
English (en)
Other versions
WO2003000842A2 (fr
Inventor
Michele L Agee
David W Anderson
Constance Berghs
Stacie J Casman
Elina Catterton
Vincent A Dipippo
Shlomit R Edinger
Andrew Eisen
Karen Ellerman
Esha A Gangolli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CuraGen Corp
Original Assignee
CuraGen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CuraGen Corp filed Critical CuraGen Corp
Priority to JP2003507229A priority Critical patent/JP2005518185A/ja
Priority to CA002447941A priority patent/CA2447941A1/fr
Priority to EP02765778A priority patent/EP1578905A2/fr
Publication of WO2003000842A2 publication Critical patent/WO2003000842A2/fr
Anticipated expiration legal-status Critical
Publication of WO2003000842A3 publication Critical patent/WO2003000842A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne de nouveaux polynucléotides isolés et des polypeptides cibles à petites molécules codés par les polynucléotides. L'invention concerne également des anticorps de liaison immunospécifique au polypeptide cible à petites molécules ou tout dérivé, variant, mutant ou fragment dudit polypeptide, polynucléotide ou anticorps ainsi que des procédés dans lesquels le polypeptide cible, polynucléotide et anticorps sont utilisés dans la détection et le traitement d'une large gamme de conditions pathologiques. Plus précisément, la présente invention décrit des procédés d'utilisation de protéines exprimées de manière recombinante et/ou endogène dans divers procédés permettant l'identification d'anticorps thérapeutiques et de petites molécules thérapeutiques associés aux maladies.
PCT/US2002/017443 2001-06-04 2002-06-04 Nouvelles proteines et acides nucleiques codant pour de telles proteines Ceased WO2003000842A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2003507229A JP2005518185A (ja) 2001-06-04 2002-06-04 新規タンパク質およびそれをコード化する核酸
CA002447941A CA2447941A1 (fr) 2001-06-04 2002-06-04 Nouvelles proteines et acides nucleiques codant pour de telles proteines
EP02765778A EP1578905A2 (fr) 2001-06-04 2002-06-04 Nouvelles proteines et acides nucleiques codant pour de telles proteines

Applications Claiming Priority (72)

Application Number Priority Date Filing Date Title
US29560701P 2001-06-04 2001-06-04
US29566101P 2001-06-04 2001-06-04
US60/295,607 2001-06-04
US60/295,661 2001-06-04
US60/295,573 2001-06-05
US29641801P 2001-06-06 2001-06-06
US29640401P 2001-06-06 2001-06-06
US60/296,418 2001-06-06
US60/296,404 2001-06-06
US29657501P 2001-06-07 2001-06-07
US60/296,575 2001-06-07
US29741401P 2001-06-11 2001-06-11
US60/297,414 2001-06-11
US29757301P 2001-06-12 2001-06-12
US29756701P 2001-06-12 2001-06-12
US60/297,567 2001-06-12
US29828501P 2001-06-14 2001-06-14
US60/298,285 2001-06-14
US29852801P 2001-06-15 2001-06-15
US60/298,528 2001-06-15
US29913301P 2001-06-18 2001-06-18
US60/299,133 2001-06-18
US29923001P 2001-06-19 2001-06-19
US60/299,230 2001-06-19
US29994901P 2001-06-21 2001-06-21
US60/299,949 2001-06-21
US30017701P 2001-06-22 2001-06-22
US60/300,177 2001-06-22
US30088301P 2001-06-26 2001-06-26
US60/300,883 2001-06-26
US30153001P 2001-06-28 2001-06-28
US30155001P 2001-06-28 2001-06-28
US60/301,530 2001-06-28
US60/301,550 2001-06-28
US30295101P 2001-07-03 2001-07-03
US60/302,951 2001-07-03
US30889001P 2001-07-31 2001-07-31
US60/308,890 2001-07-31
US32229701P 2001-09-14 2001-09-14
US60/322,297 2001-09-14
US32466901P 2001-09-25 2001-09-25
US60/324,669 2001-09-25
US33747701P 2001-12-03 2001-12-03
US60/337,477 2001-12-03
US34156201P 2001-12-14 2001-12-14
US60/341,562 2001-12-14
US35865602P 2002-02-21 2002-02-21
US35912202P 2002-02-21 2002-02-21
US60/358,656 2002-02-21
US60/359,122 2002-02-21
US35903502P 2002-02-22 2002-02-22
US35903402P 2002-02-22 2002-02-22
US35897802P 2002-02-22 2002-02-22
US35912102P 2002-02-22 2002-02-22
US60/359,121 2002-02-22
US60/359,035 2002-02-22
US60/359,034 2002-02-22
US60/358,978 2002-02-22
US35996402P 2002-02-27 2002-02-27
US60/359,964 2002-02-27
US36085802P 2002-03-01 2002-03-01
US60/360,858 2002-03-01
US36367602P 2002-03-12 2002-03-12
US36343002P 2002-03-12 2002-03-12
US60/363,676 2002-03-12
US60/363,430 2002-03-12
US37134602P 2002-04-10 2002-04-10
US60/371,346 2002-04-10
US37944402P 2002-05-10 2002-05-10
US60/379,444 2002-05-10
US16061902A 2002-06-03 2002-06-03
US10/160,619 2002-06-03

Publications (2)

Publication Number Publication Date
WO2003000842A2 WO2003000842A2 (fr) 2003-01-03
WO2003000842A3 true WO2003000842A3 (fr) 2005-11-03

Family

ID=34744079

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/017443 Ceased WO2003000842A2 (fr) 2001-06-04 2002-06-04 Nouvelles proteines et acides nucleiques codant pour de telles proteines

Country Status (2)

Country Link
JP (1) JP2005518185A (fr)
WO (1) WO2003000842A2 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9056138B2 (en) 2002-03-01 2015-06-16 Bracco Suisse Sa Multivalent constructs for therapeutic and diagnostic applications
US9295737B2 (en) 2002-03-01 2016-03-29 Bracco Suisse Sa Targeting vector-phospholipid conjugates
US9408926B2 (en) 2002-03-01 2016-08-09 Bracco Suisse S.A. KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US9446155B2 (en) 2002-03-01 2016-09-20 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US9562049B2 (en) 2012-12-21 2017-02-07 Medimmune Limited Pyrrolobenzodiazepines and conjugates thereof
US9567340B2 (en) 2012-12-21 2017-02-14 Medimmune Limited Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases

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DK2284180T3 (en) 2003-03-03 2015-12-21 Dyax Corp Uses of peptides that specifically bind to the HGF receptor (cMET)
DK1725249T3 (en) 2003-11-06 2014-03-17 Seattle Genetics Inc Monomethylvaline compounds capable of conjugating to ligands.
KR101200133B1 (ko) 2004-06-01 2012-11-13 제넨테크, 인크. 항체 약물 접합체 및 방법
ES2579805T3 (es) 2004-09-23 2016-08-16 Genentech, Inc. Anticuerpos y conjugados modificados por ingeniería genética con cisteína
US20100111856A1 (en) 2004-09-23 2010-05-06 Herman Gill Zirconium-radiolabeled, cysteine engineered antibody conjugates
JP2006217859A (ja) * 2005-02-10 2006-08-24 Japan Health Science Foundation アルツハイマー病の治療薬または予防薬のスクリーニング方法、およびアルツハイマー病を診断する方法、アルツハイマー病発症の危険度を予測する方法
EP1849877A1 (fr) * 2006-04-24 2007-10-31 Erasmus University Medical Center Rotterdam Histoire réplicative de sous-ensembles de lymphocytes T et B
DE102007017433A1 (de) * 2007-04-03 2008-10-09 Eberhard-Karls-Universität Tübingen Universitätsklinikum PIKfyve als pharmakologisches Target zur Behandlung von glucosestoffwechselassoziierten Krankheiten
WO2011031870A1 (fr) 2009-09-09 2011-03-17 Centrose, Llc Conjugués médicamenteux ciblés à visée extracellulaire
MA34277B1 (fr) 2010-04-15 2013-06-01 Spirogen Developments Sarl Pyrrolobenzodiazépines et conjugués de celles-ci
MX336540B (es) 2010-06-08 2016-01-22 Genentech Inc Conjugados y anticuerpos manipulados geneticamente con cisteina.
ES2544608T3 (es) 2010-11-17 2015-09-02 Genentech, Inc. Conjugados de anticuerpo y de alaninil-maitansinol
WO2012112955A2 (fr) 2011-02-17 2012-08-23 The Trustees Of Columbia University In The City Of New York Procédés d'identification de sujets présentant un risque génétique de développer une néphropathie à iga
KR101992502B1 (ko) 2011-05-12 2019-06-24 제넨테크, 인크. 프레임워크 시그너처 펩티드를 사용하여 동물 샘플에서 치료 항체를 검출하기 위한 다중 반응 모니터링 lc-ms/ms 방법
JP5864918B2 (ja) * 2011-07-06 2016-02-17 国立大学法人東北大学 オートタキシンアイソフォーム特異的抗体および検出方法
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9056138B2 (en) 2002-03-01 2015-06-16 Bracco Suisse Sa Multivalent constructs for therapeutic and diagnostic applications
US9295737B2 (en) 2002-03-01 2016-03-29 Bracco Suisse Sa Targeting vector-phospholipid conjugates
US9381258B2 (en) 2002-03-01 2016-07-05 Bracco Suisse S.A. Targeting vector-phospholipid conjugates
US9408926B2 (en) 2002-03-01 2016-08-09 Bracco Suisse S.A. KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US9446155B2 (en) 2002-03-01 2016-09-20 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US9562049B2 (en) 2012-12-21 2017-02-07 Medimmune Limited Pyrrolobenzodiazepines and conjugates thereof
US9567340B2 (en) 2012-12-21 2017-02-14 Medimmune Limited Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases

Also Published As

Publication number Publication date
JP2005518185A (ja) 2005-06-23
WO2003000842A2 (fr) 2003-01-03

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