[go: up one dir, main page]

WO2002038767A3 - Nouvelles proteine recepteur couplee a une proteine g et molecules d'acides nucleiques, et utilisations associees - Google Patents

Nouvelles proteine recepteur couplee a une proteine g et molecules d'acides nucleiques, et utilisations associees Download PDF

Info

Publication number
WO2002038767A3
WO2002038767A3 PCT/US2001/049696 US0149696W WO0238767A3 WO 2002038767 A3 WO2002038767 A3 WO 2002038767A3 US 0149696 W US0149696 W US 0149696W WO 0238767 A3 WO0238767 A3 WO 0238767A3
Authority
WO
WIPO (PCT)
Prior art keywords
c5rl
nucleic acid
acid molecules
protein
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/049696
Other languages
English (en)
Other versions
WO2002038767A2 (fr
Inventor
Kamalakar Gulukota
Harleen Kaur
Brian G Bates
Janet E Paulsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetics Institute LLC
Original Assignee
Genetics Institute LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Institute LLC filed Critical Genetics Institute LLC
Priority to AU2002231194A priority Critical patent/AU2002231194A1/en
Publication of WO2002038767A2 publication Critical patent/WO2002038767A2/fr
Anticipated expiration legal-status Critical
Publication of WO2002038767A3 publication Critical patent/WO2002038767A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne de nouveaux polypeptides, protéines, et molécules d'acides nucléiques C5RL. En plus des protéines C5RL pleine longueur isolées, l'invention concerne des protéines de fusion C5RL isolées, des peptides antigéniques et des anticorps anti-C5RL. Par ailleurs, l'invention concerne des molécules d'acides nucléiques C5RL, des vecteurs d'expression recombinés contenant les molécules d'acides nucléiques de l'invention, des cellules hôtes dans lesquelles ont a introduit les vecteurs d'expression et des animaux transgéniques dans lesquels un gène C5RL à été introduit ou dissocié. Enfin, l'invention concerne des méthodes diagnostiques, thérapeutiques et de criblage faisant intervenir les compositions de l'invention.
PCT/US2001/049696 2000-11-07 2001-11-07 Nouvelles proteine recepteur couplee a une proteine g et molecules d'acides nucleiques, et utilisations associees Ceased WO2002038767A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002231194A AU2002231194A1 (en) 2000-11-07 2001-11-07 G protein-coupled receptor protein and nucleic acid molecules and uses therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24655300P 2000-11-07 2000-11-07
US60/246,553 2000-11-07

Publications (2)

Publication Number Publication Date
WO2002038767A2 WO2002038767A2 (fr) 2002-05-16
WO2002038767A3 true WO2002038767A3 (fr) 2003-09-04

Family

ID=22931171

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/049696 Ceased WO2002038767A2 (fr) 2000-11-07 2001-11-07 Nouvelles proteine recepteur couplee a une proteine g et molecules d'acides nucleiques, et utilisations associees

Country Status (2)

Country Link
AU (1) AU2002231194A1 (fr)
WO (1) WO2002038767A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2561828T3 (es) 2002-01-25 2016-03-01 Novo Nordisk A/S Anticuerpos monoclonales contra bucles extracelulares de C5aR
WO2005050199A1 (fr) * 2003-10-31 2005-06-02 Bayer Healthcare Ag Diagnostics et traitements de maladies associees au recepteur 77 lie a une proteine g (gpr77)
EP1782072A2 (fr) * 2004-04-15 2007-05-09 Reglia AB Substances et procedes pour le criblage de modulateurs de la regeneration neuronale
KR20090053899A (ko) 2006-08-22 2009-05-28 지투 인플레메이션 피티와이 엘티디 개선된 특성을 갖는 항-ｃ５ａｒ 항체
CN101970494B (zh) 2008-02-20 2015-01-21 G2炎症私人有限公司 人源化抗-C5aR抗体
DK2718322T3 (en) 2011-06-06 2018-12-03 Novo Nordisk As THERAPEUTIC ANTIBODIES

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1111049A1 (fr) * 1998-09-03 2001-06-27 Asahi Kasei Kabushiki Kaisha Nouvelle proteine de recepteur et procede servant a diagnostiquer des maladies inflammatoires au moyen de cette proteine
WO2001049847A2 (fr) * 1999-12-30 2001-07-12 Millennium Pharmaceuticals, Inc. 26904, 38911 et 39404, nouvelles proteines a sept segments transmembranaires/recepteurs couples aux proteines g

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1111049A1 (fr) * 1998-09-03 2001-06-27 Asahi Kasei Kabushiki Kaisha Nouvelle proteine de recepteur et procede servant a diagnostiquer des maladies inflammatoires au moyen de cette proteine
WO2001049847A2 (fr) * 1999-12-30 2001-07-12 Millennium Pharmaceuticals, Inc. 26904, 38911 et 39404, nouvelles proteines a sept segments transmembranaires/recepteurs couples aux proteines g

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BOULAY F ET AL: "EXPRESSION CLONING OF A RECEPTOR FOR C5A ANAPHYLATOXIN ON DIFFERENTIATED HL-60 CELLS", BIOCHEMISTRY, vol. 30, no. 12, 1991, pages 2993 - 2999, XP000828087, ISSN: 0006-2960 *
OHNO MITSUHARU ET AL: "A putative chemoattractant receptor, C5L2, is expressed in granulocyte and immature dendritic cells, but not in mature dendritic cells.", MOLECULAR IMMUNOLOGY, vol. 37, no. 8, June 2000 (2000-06-01), pages 407 - 412, XP002224051, ISSN: 0161-5890 *

Also Published As

Publication number Publication date
WO2002038767A2 (fr) 2002-05-16
AU2002231194A1 (en) 2002-05-21

Similar Documents

Publication Publication Date Title
WO1999066025A3 (fr) NOUVELLES MOLECULES PROTEIQUES ET NUCLEOTIDIQUES MTbx ET LEURS APPLICATIONS
WO2002008279A3 (fr) Molecules b7-h2, nouveaux membres de la famille b7 et leurs utilisations
WO2002070652A3 (fr) Nouvelles molecules de la famille de proteines de type card et utilisations de celles-ci
EP1009752A4 (fr) Nouvelles molecules de la famille des proteines de type tango-77 et utilisations de ces molecules
WO2000052047A3 (fr) Proteine humaine et molecules d'acide nucleique associees a dickkopf et leurs utilisations
AU3217100A (en) Methods of use of a novel lysyl oxidase-related protein
WO2002044354A3 (fr) Nouvelles molecules de la famille de proteines relatives a card et leurs utilisations
WO2001000826A3 (fr) Nouvelles molecules de la famille de proteines liee a la card et utilisations de ces dernieres
WO2000019988A8 (fr) NOUVELLES MOLECULES SPECIFIQUES DE Th2 ET LEURS UTILISATIONS
WO2000046236A3 (fr) Nouvelles molecules contenant des regulateurs de signalisation de proteine g (rgs) et leurs utilisations
WO2001009328A8 (fr) Nouvelle molecule 15571 de type gpcr de la famille secretine et utilisations de cette derniere
WO2001061005A3 (fr) Nouvelles molecules de la famille de proteines du domaine pyrine, et leurs utilisations
WO2000012544A3 (fr) Nouvelles molecules d'acides nucleiques et de polypeptides irap-bp et leurs utilisations
WO2000008045A3 (fr) Nouvelles molecules de la famille de proteines apparentees a tango-93 et leurs utilisations
WO2001018216A3 (fr) Nouvelle protease calpaine 26176 et utilisations
WO2002070657A3 (fr) 93870, recepteur couple a la proteine g humaine et ses utilisations
WO1999054437A3 (fr) Nouvelles molecules de la famille des proteines liees a t125 et utilisations de celles-ci
WO2002038767A3 (fr) Nouvelles proteine recepteur couplee a une proteine g et molecules d'acides nucleiques, et utilisations associees
WO2002068591A3 (fr) Acides nucleiques du recepteur complexe a la proteine g, polypeptides, anticorps et leurs utilisations
WO2001030971A3 (fr) Nouvelles molecules de la famille des proteines se rapportant aux card et leurs utilisations
WO2001077151A3 (fr) Nouvelles molecules de proteines et d'acide nucleique fdrg et utilisation desdites molecules
WO2003029434A3 (fr) Nouvelles molecules de la famille de proteines associee a la hkid-1 et utilisations desdites molecules
WO2002085939A8 (fr) Nouvelles molecules de la famille des proteines relatives au domaine card et leurs utilisations
WO2001085768A3 (fr) Nouveaux recepteurs couples a la proteine g et utilisations de ceux-ci
WO2001059065A3 (fr) Nouvelles molecules de la famille des proteines apparentees a card et leurs utilisations

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP