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WO2002038587A3 - Haplotypes du gene grm8 - Google Patents

Haplotypes du gene grm8 Download PDF

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Publication number
WO2002038587A3
WO2002038587A3 PCT/US2001/047325 US0147325W WO0238587A3 WO 2002038587 A3 WO2002038587 A3 WO 2002038587A3 US 0147325 W US0147325 W US 0147325W WO 0238587 A3 WO0238587 A3 WO 0238587A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
grm8
gene
disclosed
grm8 gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/047325
Other languages
English (en)
Other versions
WO2002038587A2 (fr
Inventor
Karyn M Bieglecki
Anne Chew
Julie Y Choi
Beena Koshy
Katie E Parks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cogenics Inc
Original Assignee
Genaissance Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals Inc filed Critical Genaissance Pharmaceuticals Inc
Priority to AU2002236585A priority Critical patent/AU2002236585A1/en
Publication of WO2002038587A2 publication Critical patent/WO2002038587A2/fr
Publication of WO2002038587A3 publication Critical patent/WO2002038587A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne de nouvelles variantes génétiques du gène récepteur de glutamate, métabotropique 8 (GRM8). L'invention concerne également divers génotypes, haplotypes, et paires d'haplotypes pour le gène GRM8 qui existent la population générale des Etats Unis. L'invention concerne en outre des compositions et des procédés permettant le génotypage et l'haplotypage du gène GRM8 chez un individu. Enfin, l'invention concerne des polynucléotides définis par les haplotypes de l'invention.
PCT/US2001/047325 2000-11-09 2001-11-09 Haplotypes du gene grm8 Ceased WO2002038587A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002236585A AU2002236585A1 (en) 2000-11-09 2001-11-09 Haplotypes of the grm8 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24757600P 2000-11-09 2000-11-09
US60/247,576 2000-11-09

Publications (2)

Publication Number Publication Date
WO2002038587A2 WO2002038587A2 (fr) 2002-05-16
WO2002038587A3 true WO2002038587A3 (fr) 2003-01-16

Family

ID=22935426

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/047325 Ceased WO2002038587A2 (fr) 2000-11-09 2001-11-09 Haplotypes du gene grm8

Country Status (2)

Country Link
AU (1) AU2002236585A1 (fr)
WO (1) WO2002038587A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2471198A1 (fr) * 2001-12-20 2003-07-03 Merck & Co., Inc. Identification de sites polymorphes dans le gene humain mglur8 et utilisations associees

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BOLONNA ET AL.: "Polymorphisms in the genes ofr mGluR types 7 and 8: association studies with schizophrenia", SCHIZOPHRENIA RESEARCH, vol. 47, no. 1, 2001, pages 99 - 103, XP002951217 *
GOODWIN ET AL.: "No association found between polymorphisms in genes encoding mGluR7 and mGluR8 and idiopathic generalised epilepsy in a case control study", EPILEPSY RESEARCH, vol. 39, 2000, pages 27 - 31, XP002951216 *
SCHERER ET AL.: "The human metabotropic glutamate receptor 8 (GRM8) gene: a disproportionately large gene located at 7q31.3-q32.1", GENOMICS, vol. 44, 1997, pages 232 - 236, XP002104697 *

Also Published As

Publication number Publication date
AU2002236585A1 (en) 2002-05-21
WO2002038587A2 (fr) 2002-05-16

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