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WO2002032395A3 - Sustained release delivery system and uses thereof - Google Patents

Sustained release delivery system and uses thereof Download PDF

Info

Publication number
WO2002032395A3
WO2002032395A3 PCT/IL2001/000966 IL0100966W WO0232395A3 WO 2002032395 A3 WO2002032395 A3 WO 2002032395A3 IL 0100966 W IL0100966 W IL 0100966W WO 0232395 A3 WO0232395 A3 WO 0232395A3
Authority
WO
WIPO (PCT)
Prior art keywords
delivery system
sustained release
release delivery
bicellar
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2001/000966
Other languages
French (fr)
Other versions
WO2002032395A2 (en
Inventor
Frederic Amnon Kestel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADVANCED DELIVERY SYSTEMS APS
Original Assignee
ADVANCED DELIVERY SYSTEMS APS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADVANCED DELIVERY SYSTEMS APS filed Critical ADVANCED DELIVERY SYSTEMS APS
Priority to AU2002210894A priority Critical patent/AU2002210894A1/en
Publication of WO2002032395A2 publication Critical patent/WO2002032395A2/en
Publication of WO2002032395A3 publication Critical patent/WO2002032395A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to a sustained release delivery system for the delivery of an active agent to a warm-blooded animal and to uses thereof. The delivery system comprises an aqueous bicellar matrix that is liquid at temperatures below ambient temperature and forms a biodegradable gel at body temperature of said animal and an active agent, and optionally further comprises pharmaceutically acceptable additive, carrier and/or diluent. The aqueous bicellar matrix is preferably a mixture of a lipid, preferably phospholipid, and a detergent in water.
PCT/IL2001/000966 2000-10-20 2001-10-18 Sustained release delivery system and uses thereof Ceased WO2002032395A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002210894A AU2002210894A1 (en) 2000-10-20 2001-10-18 Sustained release delivery system and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13917700A IL139177A0 (en) 2000-10-20 2000-10-20 Sustained release drug delivery system
IL139177 2000-10-20

Publications (2)

Publication Number Publication Date
WO2002032395A2 WO2002032395A2 (en) 2002-04-25
WO2002032395A3 true WO2002032395A3 (en) 2002-12-19

Family

ID=11074743

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2001/000966 Ceased WO2002032395A2 (en) 2000-10-20 2001-10-18 Sustained release delivery system and uses thereof

Country Status (3)

Country Link
AU (1) AU2002210894A1 (en)
IL (1) IL139177A0 (en)
WO (1) WO2002032395A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1888038A2 (en) * 2005-05-10 2008-02-20 Novartis AG Modified release famciclovir pharmaceutical compositions
EP2040725B1 (en) 2006-06-23 2014-01-15 EnGeneIC Molecular Delivery Pty Ltd. Targeted delivery of drugs, therapeutic nucleic acids and functional nucleic acids to mammalian cells via intact killed bacterial cells
ES2364771B1 (en) * 2010-03-01 2013-01-29 Consejo Superior De Investigaciones Científicas (Csic) BICELAS ENCAPSULADAS IN LIPOSOMAS AND ITS APPLICATION IN DILUIDED SYSTEMS.
RU2595865C2 (en) 2010-08-20 2016-08-27 Др. Редди'З Лабораториз, Лтд. Phospholipid depot preparation
CA2814577C (en) 2010-10-22 2019-06-04 Dr. Reddy`S Laboratories, Inc. Use of storage stable viscous phospholipid depot to treat wounds
JP2015516411A (en) 2012-05-10 2015-06-11 ペインレフォーム リミテッド Depot formulation of hydrophobic active ingredient and method for preparing the same
JP6539274B2 (en) 2013-08-12 2019-07-03 ファーマシューティカル マニュファクチュアリング リサーチ サービシズ，インコーポレーテッド Extruded immediate release abuse deterrent pills
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
EA201692083A1 (en) 2014-04-16 2017-03-31 Вейкс-Фарма Гмбх PHARMACEUTICAL COMPOSITION FOR VETERINARY AND ITS APPLICATION
WO2016010771A1 (en) 2014-07-17 2016-01-21 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
JP2017531026A (en) 2014-10-20 2017-10-19 ファーマシューティカル マニュファクチュアリング リサーチ サービシズ，インコーポレーテッド Sustained release abuse deterrent liquid filler form

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0475160A1 (en) * 1990-08-24 1992-03-18 Gregor Prof. Dr. Cevc Preparation for drug application in minute droplet form
EP0730860A2 (en) * 1995-03-07 1996-09-11 F. Hoffmann-La Roche Ag Mixed micelles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0475160A1 (en) * 1990-08-24 1992-03-18 Gregor Prof. Dr. Cevc Preparation for drug application in minute droplet form
EP0730860A2 (en) * 1995-03-07 1996-09-11 F. Hoffmann-La Roche Ag Mixed micelles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FRANK RINALDI; ET AL.: "Delta-Opiate DPDPE in Magnetically Oriented Phospholipid Micelles: Binding and Arrangement of Aromatic Pharmacophores", BIOPHYSICAL JOURNAL, vol. 73, no. 6, December 1997 (1997-12-01), pages 3337 - 3348, XP008008942 *

Also Published As

Publication number Publication date
AU2002210894A1 (en) 2002-04-29
WO2002032395A2 (en) 2002-04-25
IL139177A0 (en) 2001-11-25

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