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WO2002030969A3 - Regulation une enzyme humaine de type carboxyesterase - Google Patents

Regulation une enzyme humaine de type carboxyesterase Download PDF

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Publication number
WO2002030969A3
WO2002030969A3 PCT/EP2001/011758 EP0111758W WO0230969A3 WO 2002030969 A3 WO2002030969 A3 WO 2002030969A3 EP 0111758 W EP0111758 W EP 0111758W WO 0230969 A3 WO0230969 A3 WO 0230969A3
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme
human carboxylesterase
regulation
reagents
carboxylesterase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/011758
Other languages
English (en)
Other versions
WO2002030969A2 (fr
Inventor
Zhimin Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to AU2002215942A priority Critical patent/AU2002215942A1/en
Publication of WO2002030969A2 publication Critical patent/WO2002030969A2/fr
Publication of WO2002030969A3 publication Critical patent/WO2002030969A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des réactifs régulant l'enzyme humaine de type carboxyésterase et des réactifs se liant à des produits géniques d'enzyme humaine de type carboxyésterase, pouvant intervenir dans la prévention, l'amélioration ou la correction de dysfonctionnement ou de maladies parmi lesquelles, des maladies liées à l'intoxication par organophosphores, au cancer, et à la bronchopneumopathie chronique obstructive (BPCO).
PCT/EP2001/011758 2000-10-13 2001-10-11 Regulation une enzyme humaine de type carboxyesterase Ceased WO2002030969A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002215942A AU2002215942A1 (en) 2000-10-13 2001-10-11 Regulation of human carboxylesterase-like enzyme

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23989800P 2000-10-13 2000-10-13
US60/239,898 2000-10-13
US31594701P 2001-08-31 2001-08-31
US60/315,947 2001-08-31

Publications (2)

Publication Number Publication Date
WO2002030969A2 WO2002030969A2 (fr) 2002-04-18
WO2002030969A3 true WO2002030969A3 (fr) 2002-09-12

Family

ID=26932976

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/011758 Ceased WO2002030969A2 (fr) 2000-10-13 2001-10-11 Regulation une enzyme humaine de type carboxyesterase

Country Status (2)

Country Link
AU (1) AU2002215942A1 (fr)
WO (1) WO2002030969A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110020801A1 (en) * 2007-06-08 2011-01-27 Markowitz John S Carboxylesterase-1 Polymorphisms and Methods of Use Therefor
CN114717216A (zh) * 2022-03-31 2022-07-08 石河子大学 一种棉酚降解酶CCE001a基因、氨基酸序列及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001625A (en) * 1995-05-19 1999-12-14 The United States Of America As Represented By The Secretary Of The Army Site-directed mutagenesis of esterases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001625A (en) * 1995-05-19 1999-12-14 The United States Of America As Represented By The Secretary Of The Army Site-directed mutagenesis of esterases

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] EBI, Hinxton, UK; 15 December 1992 (1992-12-15), KROETZ ET AL.: "Human carboxylesterase mRNA, complete cds.", XP002198156, Database accession no. L07765 *
DATABASE EMBL [online] EBI, Hinxton, UK; 31 July 1991 (1991-07-31), ZSCHUNKE ET AL.: "Human mRNA for monocyte/macrophage serine-esterase 1, partial", XP002198157, Database accession no. X52973 *
DATABASE EMBL [online] EBI, Hinxton, UK; 7 September 1999 (1999-09-07), ISLAM ET AL.: "Homo sapiens egasyn mRNA, complete cds.", XP002198158, Database accession no. AF177775 *

Also Published As

Publication number Publication date
WO2002030969A2 (fr) 2002-04-18
AU2002215942A1 (en) 2002-04-22

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