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WO2002020062A3 - Coated implant - Google Patents

Coated implant Download PDF

Info

Publication number
WO2002020062A3
WO2002020062A3 PCT/EP2001/009873 EP0109873W WO0220062A3 WO 2002020062 A3 WO2002020062 A3 WO 2002020062A3 EP 0109873 W EP0109873 W EP 0109873W WO 0220062 A3 WO0220062 A3 WO 0220062A3
Authority
WO
WIPO (PCT)
Prior art keywords
coated implant
implant
layers
radioactive isotope
noble metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/009873
Other languages
German (de)
French (fr)
Other versions
WO2002020062A2 (en
Inventor
Anton Moeslang
Andreas Przykutta
Eric Walch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Karlsruher Institut fuer Technologie KIT
Original Assignee
Forschungszentrum Karlsruhe GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungszentrum Karlsruhe GmbH filed Critical Forschungszentrum Karlsruhe GmbH
Priority to EP01976155A priority Critical patent/EP1315524A2/en
Publication of WO2002020062A2 publication Critical patent/WO2002020062A2/en
Publication of WO2002020062A3 publication Critical patent/WO2002020062A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N2005/1019—Sources therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002—Intraluminal radiation therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Radiation-Therapy Devices (AREA)
  • Prostheses (AREA)

Abstract

The invention relates to a coated implant, the coating thereof consisting of at least one noble metal and one metal containing at least one radioactive isotope. The aim of the invention is to provide a coated implant having a low elution rate. In order to achieve this, the coating consists of at least two layers, one layer being made of noble metal and another being made of a metal containing at least one radioactive isotope. Said layers are electrochemically applied to the implant and are then tempered.
PCT/EP2001/009873 2000-09-08 2001-08-28 Coated implant Ceased WO2002020062A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP01976155A EP1315524A2 (en) 2000-09-08 2001-08-28 Coated implant

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2000144559 DE10044559A1 (en) 2000-09-08 2000-09-08 Coated implant
DE10044559.4 2000-09-08

Publications (2)

Publication Number Publication Date
WO2002020062A2 WO2002020062A2 (en) 2002-03-14
WO2002020062A3 true WO2002020062A3 (en) 2002-10-03

Family

ID=7655581

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/009873 Ceased WO2002020062A2 (en) 2000-09-08 2001-08-28 Coated implant

Country Status (3)

Country Link
EP (1) EP1315524A2 (en)
DE (1) DE10044559A1 (en)
WO (1) WO2002020062A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10142015C2 (en) * 2001-08-28 2003-08-28 Karlsruhe Forschzent Radioactive implant and process for its manufacture
DE10361942A1 (en) 2003-12-24 2005-07-21 Restate Patent Ag Radioopaque marker for medical implants
JP2010526625A (en) 2007-05-15 2010-08-05 カメレオン バイオサーフェセズ リミテッド Polymer coating on medical devices
DE102008054920A1 (en) * 2008-12-18 2010-07-01 Biotronik Vi Patent Ag Implant and method for producing a layer structure

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19724229C1 (en) * 1997-04-30 1999-04-01 Schering Ag Radioactive stents used in the production of implant for restenosis prophylaxis
WO2000009212A2 (en) * 1998-08-13 2000-02-24 Nycomed Amersham Plc Apparatus and methods for radiotherapy
WO2000029035A1 (en) * 1998-11-13 2000-05-25 Global Vascular Concepts, Inc. X-ray emitting surgical device
WO2000057956A1 (en) * 1999-03-26 2000-10-05 Implant Sciences Corporation Method of manufacturing radioactive medical devices
EP1149592A2 (en) * 2000-04-28 2001-10-31 MDS Nordion Inc. Radioactively coated devices

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6174329B1 (en) * 1996-08-22 2001-01-16 Advanced Cardiovascular Systems, Inc. Protective coating for a stent with intermediate radiopaque coating
US5919126A (en) * 1997-07-07 1999-07-06 Implant Sciences Corporation Coronary stent with a radioactive, radiopaque coating
DE19916086B4 (en) * 1998-04-11 2004-11-11 Inflow Dynamics Inc. Implantable prosthesis, especially vascular prosthesis (stent)
DE19906417C1 (en) * 1999-02-16 2000-06-29 Heraeus Gmbh W C Passage opening support structure, especially a medical stent, has a gold layer between a special steel substrate and a platinum surface layer to avoid platinum cracking

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19724229C1 (en) * 1997-04-30 1999-04-01 Schering Ag Radioactive stents used in the production of implant for restenosis prophylaxis
WO2000009212A2 (en) * 1998-08-13 2000-02-24 Nycomed Amersham Plc Apparatus and methods for radiotherapy
WO2000029035A1 (en) * 1998-11-13 2000-05-25 Global Vascular Concepts, Inc. X-ray emitting surgical device
WO2000057956A1 (en) * 1999-03-26 2000-10-05 Implant Sciences Corporation Method of manufacturing radioactive medical devices
EP1149592A2 (en) * 2000-04-28 2001-10-31 MDS Nordion Inc. Radioactively coated devices

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DEBBAS, N. (1) ET AL: "Production of 103Pd radioactive stents: A potential tool to prevent coronary restenosis following percutaneous transluminal coronary angioplasty.", RADIOTHERAPY & ONCOLOGY, (SEPTEMBER, 2000) VOL. 56, NO. SUPPLEMENT 1, PP. S135. PRINT. MEETING INFO.: 19TH ANNUAL MEETING OF THE EUROPEAN SOCIETY FOR THERAPEUTI RADIOLOGY AND ONCOLOGY ISTANBUL, TURKEY SEPTEMBER 19-23, 2000, XP008004592 *
FREY, A. W. (1) ET AL: "Feasability of Pd-103 coating to manufacture a new radioactive: X-ray emitting: Stent.", EUROPEAN HEART JOURNAL, (AUGUST SEPTEMBER, 2000) VOL. 21, NO. ABSTRACT SUPPLEMENT, PP. 399. PRINT. MEETING INFO.: XXII CONGRESS OF THE EUROPEAN SOCIETY OF CARDIOLOGY AMSTERDAM, NETHERLANDS AUGUST 26-30, 2000 EUROPEAN SOCIETY OF CARDIOLOGY., XP001073952 *

Also Published As

Publication number Publication date
EP1315524A2 (en) 2003-06-04
WO2002020062A2 (en) 2002-03-14
DE10044559A1 (en) 2002-04-04

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