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WO2002018945A3 - Puce d'analyse - Google Patents

Puce d'analyse Download PDF

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Publication number
WO2002018945A3
WO2002018945A3 PCT/EP2001/009286 EP0109286W WO0218945A3 WO 2002018945 A3 WO2002018945 A3 WO 2002018945A3 EP 0109286 W EP0109286 W EP 0109286W WO 0218945 A3 WO0218945 A3 WO 0218945A3
Authority
WO
WIPO (PCT)
Prior art keywords
molecules
code
immobilised
chip
area
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/009286
Other languages
German (de)
English (en)
Other versions
WO2002018945A2 (fr
Inventor
Ralph Mueller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sygnis Pharma AG
Original Assignee
BASF Lynx Bioscience AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF Lynx Bioscience AG filed Critical BASF Lynx Bioscience AG
Priority to AU2002212136A priority Critical patent/AU2002212136A1/en
Publication of WO2002018945A2 publication Critical patent/WO2002018945A2/fr
Publication of WO2002018945A3 publication Critical patent/WO2002018945A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B01J2219/00529—DNA chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00542—Alphanumeric characters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00547—Bar codes
    • B01J2219/00549—2-dimensional
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00608—DNA chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/0061—The surface being organic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00702—Processes involving means for analysing and characterising the products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne une puce d'analyse (10), par exemple un jeu ordonné d'échantillons d'ADN, sur laquelle sont immobilisées différents types de molécules respectivement dans différentes zones spatiales (14). Chaque type de molécules d'une zone spatiale (24) correspondante est associé à un code correspondant qui indique le type des molécules immobilisées dans la zone respective. Ce code peut être composé selon la disposition des molécules. Si, par exemple, dans une zone de 5x5 points seuls certains points sont occupés, on a un code binaire. En variante, le code (24) est représenté sur la puce quelles que soient les molécules immobilisées, par exemple, sous forme de code binaire bidimensionnel. L'utilisation du jeu ordonné d'échantillons d'ADN permet d'augmenter le degré de sécurité. En effet, lors de la lecture de la puce à l'aide du code respectif lui-même, on peut même déterminer quelle molécule cible a été liée et donc quelles molécules sont contenues dans l'échantillon sans avoir recours à des informations extérieures.
PCT/EP2001/009286 2000-08-30 2001-08-10 Puce d'analyse Ceased WO2002018945A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002212136A AU2002212136A1 (en) 2000-08-30 2001-08-10 Analysis chip

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2000142797 DE10042797C2 (de) 2000-08-30 2000-08-30 Analysen-Chip
DE10042797.9 2000-08-30

Publications (2)

Publication Number Publication Date
WO2002018945A2 WO2002018945A2 (fr) 2002-03-07
WO2002018945A3 true WO2002018945A3 (fr) 2002-06-27

Family

ID=7654438

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/009286 Ceased WO2002018945A2 (fr) 2000-08-30 2001-08-10 Puce d'analyse

Country Status (3)

Country Link
AU (1) AU2002212136A1 (fr)
DE (1) DE10042797C2 (fr)
WO (1) WO2002018945A2 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030017455A1 (en) * 2001-01-29 2003-01-23 Webb Peter G. Chemical array fabrication with identity map
US20020142318A1 (en) * 2001-03-30 2002-10-03 Cattell Herbert F. Chemical array reading
US20050135964A1 (en) * 2003-12-22 2005-06-23 Ulrich Sieben Carrier medium for analyzing a substance
US20050049796A1 (en) * 2003-09-03 2005-03-03 Webb Peter G. Methods for encoding non-biological information on microarrays
KR100624420B1 (ko) * 2004-04-10 2006-09-19 삼성전자주식회사 마이크로어레이에 대한 정보가 스팟의 형태로 저장되어있는 마이크로어레이, 그를 제조하는 방법 및 그를이용하는 방법
WO2008096318A2 (fr) * 2007-02-09 2008-08-14 Koninklijke Philips Electronics N.V. Système d'identification
WO2009091039A1 (fr) * 2008-01-16 2009-07-23 Nippon Telegraph And Telephone Corporation Dispositif de mesure à résonance plasmonique de surface, cellule d'échantillon, et procédé de mesure
DE102009019476A1 (de) * 2009-05-04 2010-11-11 Biametrics Marken Und Rechte Gmbh Wiedererkennbarer Träger für optische Meßverfahren
EP2737082A1 (fr) * 2011-07-27 2014-06-04 Scienion AG Dispositif marqué
EP2933017A1 (fr) * 2014-04-17 2015-10-21 AyoxxA Biosystems GmbH Dispositif codé et procédé de codage et de décodage de zones de référence sur un substrat
WO2018144531A1 (fr) 2017-02-01 2018-08-09 Illumina, Inc. Système et procédé avec repères répondant à de multiples fréquences d'excitation
GB201701689D0 (en) 2017-02-01 2017-03-15 Illumia Inc System and method with fiducials of non-closed shapes
GB201701688D0 (en) 2017-02-01 2017-03-15 Illumia Inc System and method with fiducials in non-recliner layouts
GB201701686D0 (en) 2017-02-01 2017-03-15 Illunina Inc System & method with fiducials having offset layouts
GB201701691D0 (en) 2017-02-01 2017-03-15 Illumina Inc System and method with reflective fiducials

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0799897A1 (fr) * 1996-04-04 1997-10-08 Affymetrix, Inc. (a California Corporation) Méthodes et compositions pour sélectionner tag acides nucléiques et épreuves correspondantes
US5935785A (en) * 1997-04-30 1999-08-10 Motorola, Inc. Binding assay methods
WO2000014197A1 (fr) * 1998-09-09 2000-03-16 Hitachi Software Engineering Co., Ltd. Biopuce et procede d'utilisation de la biopuce
WO2000023803A1 (fr) * 1998-10-16 2000-04-27 Millstein Larry S Procedes permettant de creer des reseaux a motifs de molecules de liaison d'analytes
WO2000051058A1 (fr) * 1999-02-26 2000-08-31 General Scanning, Inc. Imagerie automatique et analyse de biopuces d'ensembles de microechantillons
WO2000073504A2 (fr) * 1999-06-01 2000-12-07 Hitachi Software Engineering Co., Ltd. Puce a microreseau et son procede d'indexation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2097925T3 (es) * 1991-09-18 1997-04-16 Affymax Tech Nv Metodo para sintetizar diversas colecciones de oligomeros.
US5736332A (en) * 1995-11-30 1998-04-07 Mandecki; Wlodek Method of determining the sequence of nucleic acids employing solid-phase particles carrying transponders

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0799897A1 (fr) * 1996-04-04 1997-10-08 Affymetrix, Inc. (a California Corporation) Méthodes et compositions pour sélectionner tag acides nucléiques et épreuves correspondantes
US5935785A (en) * 1997-04-30 1999-08-10 Motorola, Inc. Binding assay methods
WO2000014197A1 (fr) * 1998-09-09 2000-03-16 Hitachi Software Engineering Co., Ltd. Biopuce et procede d'utilisation de la biopuce
EP1048723A1 (fr) * 1998-09-09 2000-11-02 Hitachi Software Engineering Co., Ltd. Biopuce et procede d'utilisation de la biopuce
WO2000023803A1 (fr) * 1998-10-16 2000-04-27 Millstein Larry S Procedes permettant de creer des reseaux a motifs de molecules de liaison d'analytes
WO2000051058A1 (fr) * 1999-02-26 2000-08-31 General Scanning, Inc. Imagerie automatique et analyse de biopuces d'ensembles de microechantillons
WO2000073504A2 (fr) * 1999-06-01 2000-12-07 Hitachi Software Engineering Co., Ltd. Puce a microreseau et son procede d'indexation

Also Published As

Publication number Publication date
AU2002212136A1 (en) 2002-03-13
WO2002018945A2 (fr) 2002-03-07
DE10042797A1 (de) 2002-03-28
DE10042797C2 (de) 2003-12-04

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