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WO2002014491A3 - A hematopoietic growth factor-like protein obtained from a cdnalibrary from hs-5 stromal cell line - Google Patents

A hematopoietic growth factor-like protein obtained from a cdnalibrary from hs-5 stromal cell line Download PDF

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Publication number
WO2002014491A3
WO2002014491A3 PCT/US2001/025228 US0125228W WO0214491A3 WO 2002014491 A3 WO2002014491 A3 WO 2002014491A3 US 0125228 W US0125228 W US 0125228W WO 0214491 A3 WO0214491 A3 WO 0214491A3
Authority
WO
WIPO (PCT)
Prior art keywords
growth factor
hematopoietic growth
cell line
protein
stromal cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/025228
Other languages
French (fr)
Other versions
WO2002014491A2 (en
Inventor
Parul D Doshi
Rajeev Aurora
Martin F Meier
Cynthia L Woods
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia LLC
Original Assignee
Pharmacia LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia LLC filed Critical Pharmacia LLC
Priority to AU2001283315A priority Critical patent/AU2001283315A1/en
Publication of WO2002014491A2 publication Critical patent/WO2002014491A2/en
Anticipated expiration legal-status Critical
Publication of WO2002014491A3 publication Critical patent/WO2002014491A3/en
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to a new hematopoietic growth factor-like protein obtained from a cDNA library from HS-5 stromal cell line, nucleic acid molecules that encode the hematopoietic growth factor-like protein or a fragment thereof and nucleic acid molecules that are useful as robes or primers for detecting or amplifying the hematopoietic growth factor-like protein, respectively. The invention further relates to uses of hematopoietic growth factor-like protein. The invention also relates to applications of the factor or fragment such as forming antibodies capable of binding the factor or fragments thereof.
PCT/US2001/025228 2000-08-10 2001-08-10 A hematopoietic growth factor-like protein obtained from a cdnalibrary from hs-5 stromal cell line Ceased WO2002014491A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001283315A AU2001283315A1 (en) 2000-08-10 2001-08-10 A hematopoietic growth factor-like protein obtained from a cdnalibrary from hs-5 stromal cell line

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63642200A 2000-08-10 2000-08-10
US09/636,422 2000-08-10

Publications (2)

Publication Number Publication Date
WO2002014491A2 WO2002014491A2 (en) 2002-02-21
WO2002014491A3 true WO2002014491A3 (en) 2003-03-27

Family

ID=24551823

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/025228 Ceased WO2002014491A2 (en) 2000-08-10 2001-08-10 A hematopoietic growth factor-like protein obtained from a cdnalibrary from hs-5 stromal cell line

Country Status (2)

Country Link
AU (1) AU2001283315A1 (en)
WO (1) WO2002014491A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999006548A2 (en) * 1997-08-01 1999-02-11 Genset 5'ESTs FOR NON TISSUE SPECIFIC SECRETED PROTEINS
WO1999035252A2 (en) * 1998-01-02 1999-07-15 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO2001042451A2 (en) * 1999-12-08 2001-06-14 Genset FULL-LENGTH HUMAN cDNAs ENCODING POTENTIALLY SECRETED PROTEINS

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999006548A2 (en) * 1997-08-01 1999-02-11 Genset 5'ESTs FOR NON TISSUE SPECIFIC SECRETED PROTEINS
WO1999035252A2 (en) * 1998-01-02 1999-07-15 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO2001042451A2 (en) * 1999-12-08 2001-06-14 Genset FULL-LENGTH HUMAN cDNAs ENCODING POTENTIALLY SECRETED PROTEINS

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 28 January 1999 (1999-01-28), NCI-CGAP: "tf96a07.x1 NCI_CGAP_CLL1 Homo sapiens cDNA clone IMAGE: 2107092", XP002220808, retrieved from EBI Database accession no. AI380391 *
DATABASE EMBL [online] 31 October 1997 (1997-10-31), NCI-CGAP: "np74b10.s1 NCI_CGAP_Br2 Homo sapiens cDNA clone IMAGE: 1132027", XP002220807, retrieved from EBI Database accession no. AA632004 *
ROECKLEIN B A ET AL: "FUNCTIONALLY DISTINCT HUMAN MARROW STROMAL CELL LINES IMMORTALIZED BY TRANSDUCTION WITH THE HUMAN PAPILLOMA VIRUS E6/E7 GENES", BLOOD, W.B. SAUNDERS, PHILADELPHIA, VA, US, vol. 85, no. 4, 15 February 1995 (1995-02-15), pages 997 - 1005, XP000676357, ISSN: 0006-4971 *

Also Published As

Publication number Publication date
AU2001283315A1 (en) 2002-02-25
WO2002014491A2 (en) 2002-02-21

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